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The map label for this gene is dapB

Identifier: 158338647

GI number: 158338647

Start: 5603781

End: 5604608

Strand: Direct

Name: dapB

Synonym: AM1_5551

Alternate gene names: 158338647

Gene position: 5603781-5604608 (Clockwise)

Preceding gene: 158338640

Following gene: 158338648

Centisome position: 86.16

GC content: 46.5

Gene sequence:

>828_bases
ATGACAAATGCAACGCCAACTCCCGTTATCGTCACTGGAGCCGCTGGCAAAATGGGGCGGGAAGTGATCAAAGCTGTAGT
CCAGGCCGATGACTTGAGACTCTATGCTGCGGTTGACCGCAATCCTGACGTGTTTAGTCTAGATGCAGGGGAGCTTGTTG
GTCTTGACACTTTAAATATTGAATTGACCAATGAACTTGAACCGGTTTTAGCAGCAGCGGCCCAAGAGAAACAGCCCTGT
GTCATGGTGGACTTTACCCATCCCAGCTCCGTTTACAGCAATATCAGATCTGCGATCGCATATGGAGTATTTCCAGTAAT
CGGCACCACTGGCCTTAGCGATGAGCAAATGAATGATCTGACTGAATTTACTGAAAAAGCCAGTATGGGTTGTTTGGTCA
TTCCCAACTTCTCCATTGGTATGGTGCTATTACAACAGGCTGCCGTTCAAGCCTCCCAATATTTTGACCATGTCGAAATT
ATTGAACTACACCACAATCAGAAAGCAGATGCACCCAGTGGAACTGCCGTTAAAACGGCTCAATTACTCGGTGATTTAGG
CAAAACCTATAACCCTGCCCTGGTCGAAGAGAAAGAGCATTTAGCTGGTGCTAGGGGTAGTCTAGGTAGCGAAAATATTC
GAATTCATAGTATTCGGCTGCCAGGATTAATTGCTCACCAAGAAGTTTTATTTGGTGCCCCTGGTCAACTCTATACCTTG
CGCCATGACACGAGCGATCGGGCCTGCTATATGCCGGGTGTTCTGCTTTCTATTCGAAAAGTTACCCAGTTACAAACTCT
GAGTTATGGATTGGAGAAAATCCTGTAG

Upstream 100 bases:

>100_bases
CTCGAGTCAGAGATCCACCGTCATATTTATACTCAGGGCAATTCAAGATGGCCTCTATATTGATAAAGTCAGATCAGTAG
GTCAATCGAGCAGTTCAACC

Downstream 100 bases:

>100_bases
CTCTCTAAAAAACCTGGGTTATGCAACAGCATGAAGCTGGACTGATAGACCGGCAGACGTTCAAATTGAGGTGAATACGT
TTGTCTATGATTATCCTCTA

Product: dihydrodipicolinate reductase

Products: NA

Alternate protein names: DHPR

Number of amino acids: Translated: 275; Mature: 274

Protein sequence:

>275_residues
MTNATPTPVIVTGAAGKMGREVIKAVVQADDLRLYAAVDRNPDVFSLDAGELVGLDTLNIELTNELEPVLAAAAQEKQPC
VMVDFTHPSSVYSNIRSAIAYGVFPVIGTTGLSDEQMNDLTEFTEKASMGCLVIPNFSIGMVLLQQAAVQASQYFDHVEI
IELHHNQKADAPSGTAVKTAQLLGDLGKTYNPALVEEKEHLAGARGSLGSENIRIHSIRLPGLIAHQEVLFGAPGQLYTL
RHDTSDRACYMPGVLLSIRKVTQLQTLSYGLEKIL

Sequences:

>Translated_275_residues
MTNATPTPVIVTGAAGKMGREVIKAVVQADDLRLYAAVDRNPDVFSLDAGELVGLDTLNIELTNELEPVLAAAAQEKQPC
VMVDFTHPSSVYSNIRSAIAYGVFPVIGTTGLSDEQMNDLTEFTEKASMGCLVIPNFSIGMVLLQQAAVQASQYFDHVEI
IELHHNQKADAPSGTAVKTAQLLGDLGKTYNPALVEEKEHLAGARGSLGSENIRIHSIRLPGLIAHQEVLFGAPGQLYTL
RHDTSDRACYMPGVLLSIRKVTQLQTLSYGLEKIL
>Mature_274_residues
TNATPTPVIVTGAAGKMGREVIKAVVQADDLRLYAAVDRNPDVFSLDAGELVGLDTLNIELTNELEPVLAAAAQEKQPCV
MVDFTHPSSVYSNIRSAIAYGVFPVIGTTGLSDEQMNDLTEFTEKASMGCLVIPNFSIGMVLLQQAAVQASQYFDHVEII
ELHHNQKADAPSGTAVKTAQLLGDLGKTYNPALVEEKEHLAGARGSLGSENIRIHSIRLPGLIAHQEVLFGAPGQLYTLR
HDTSDRACYMPGVLLSIRKVTQLQTLSYGLEKIL

Specific function: Biosynthesis of diaminopimelate and lysine from aspartate semialdehyde; second step. [C]

COG id: COG0289

COG function: function code E; Dihydrodipicolinate reductase

Gene ontology:
GO:0005488: Dihydrodipicolinate reductase
GO:0005737: Dihydrodipicolinate reductase
GO:0008652: Dihydrodipicolinate reductase
GO:0008839: Dihydrodipicolinate reductase
GO:0009085: Dihydrodipicolinate reductase
GO:0009089: Dihydrodipicolinate reductase
GO:0016491: Dihydrodipicolinate reductase
GO:0019877: Dihydrodipicolinate reductase
GO:0055114: Dihydrodipicolinate reductase
GO:0070402: Dihydrodipicolinate reductase

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dihydrodipicolinate reductase family

Homologues:

Organism=Escherichia coli, GI1786214, Length=275, Percent_Identity=27.6363636363636, Blast_Score=95, Evalue=6e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DAPB_ACAM1 (B0CE31)

Other databases:

- EMBL:   CP000828
- RefSeq:   YP_001519824.1
- ProteinModelPortal:   B0CE31
- SMR:   B0CE31
- GeneID:   5684342
- GenomeReviews:   CP000828_GR
- KEGG:   amr:AM1_5551
- HOGENOM:   HBG594002
- OMA:   NGAAKEI
- BioCyc:   AMAR329726:AM1_5551-MONOMER
- GO:   GO:0005737
- GO:   GO:0005488
- HAMAP:   MF_00102
- InterPro:   IPR022663
- InterPro:   IPR000846
- InterPro:   IPR022664
- InterPro:   IPR011770
- InterPro:   IPR016040
- Gene3D:   G3DSA:3.40.50.720
- PANTHER:   PTHR20836
- TIGRFAMs:   TIGR00036

Pfam domain/function: PF05173 DapB_C; PF01113 DapB_N

EC number: =1.3.1.26

Molecular weight: Translated: 29639; Mature: 29508

Theoretical pI: Translated: 4.96; Mature: 4.96

Prosite motif: PS01298 DAPB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNATPTPVIVTGAAGKMGREVIKAVVQADDLRLYAAVDRNPDVFSLDAGELVGLDTLNI
CCCCCCCCEEEECCCCHHHHHHHHHHHHHCCEEEEEEECCCCCEEEECCCCEECCEEEEE
ELTNELEPVLAAAAQEKQPCVMVDFTHPSSVYSNIRSAIAYGVFPVIGTTGLSDEQMNDL
EECCHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
TEFTEKASMGCLVIPNFSIGMVLLQQAAVQASQYFDHVEIIELHHNQKADAPSGTAVKTA
HHHHHHHCCCEEEECCCCHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCHHHHH
QLLGDLGKTYNPALVEEKEHLAGARGSLGSENIRIHSIRLPGLIAHQEVLFGAPGQLYTL
HHHHHHCCCCCCHHHCCHHHHCCCCCCCCCCCEEEEEEECCCEEEHHHHHCCCCCCEEEE
RHDTSDRACYMPGVLLSIRKVTQLQTLSYGLEKIL
EECCCCCEEECCHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TNATPTPVIVTGAAGKMGREVIKAVVQADDLRLYAAVDRNPDVFSLDAGELVGLDTLNI
CCCCCCCEEEECCCCHHHHHHHHHHHHHCCEEEEEEECCCCCEEEECCCCEECCEEEEE
ELTNELEPVLAAAAQEKQPCVMVDFTHPSSVYSNIRSAIAYGVFPVIGTTGLSDEQMNDL
EECCHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
TEFTEKASMGCLVIPNFSIGMVLLQQAAVQASQYFDHVEIIELHHNQKADAPSGTAVKTA
HHHHHHHCCCEEEECCCCHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCHHHHH
QLLGDLGKTYNPALVEEKEHLAGARGSLGSENIRIHSIRLPGLIAHQEVLFGAPGQLYTL
HHHHHHCCCCCCHHHCCHHHHCCCCCCCCCCCEEEEEEECCCEEEHHHHHCCCCCCEEEE
RHDTSDRACYMPGVLLSIRKVTQLQTLSYGLEKIL
EECCCCCEEECCHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA