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The map label for this gene is 158338486

Identifier: 158338486

GI number: 158338486

Start: 5449117

End: 5450742

Strand: Reverse

Name: 158338486

Synonym: AM1_5388

Alternate gene names: NA

Gene position: 5450742-5449117 (Counterclockwise)

Preceding gene: 158338487

Following gene: 158338477

Centisome position: 83.81

GC content: 52.77

Gene sequence:

>1626_bases
GTGGGACCGTTGCTGTGGGGGTTGGCCTTCGCCCTGCTCCCCCTACCGCTCAAAGCTCAGGAAGGACTGCAGGACTATGA
TCATTGGGCAGGATTATGTCAGAGCCTGACTCAGCAGAAGCAATATGAAGACGCTCTGAAAGCCTGTGACCAGGCGATTG
CCTTAAATACCAACGATCCGCAGACATGGATAGATCGCAGCACAATTGTATTTGCCCTAGCCAAACATTCAGATGCCGTT
GCCGCTTTTAACCAGGTGCTCAAGCTGAAGCCGGATGAGCCCCAGATTTTGGCAAAGCGTTGTATCAGCCTTTTTAAATT
GAAAAACTATGAGCCCGCGCTTAAGGATTGTGAGTTGGCCCTCCAAGTGGCGGATCAACGAGGGCAATCGCTACCAGATC
AAGCCTGGTATTACCGGAGTGCAGCTCTGTTTAAGCTGGAGCGGTTAGAGGAAGCCCTGGCTGCTTATGACTGGGCCACC
CATATTCATAGCCGAGATGGCCGGGCTTGGGCCGATCGCTGTCAGGTCTTGGCCGCACTCAAGCAATATTCCTTGGCGTT
TCAATCCTGCGATCGCGCCCTCCGAGGCGACAGTGATTGGGGAGGCAGTTCTCCCGCAATAGGCTGGTCCCAACTTGCTC
AACTACACCGACAATTAGGGGATTACAACCAGGCCCTCAAAGGTTATGACAAGGCGCTTGCCTTTGCGCCTAAGGATTCC
CAACTATGGTCTCAGCAAGGGATTTTGCTGGATCAATTGGGAGAACATCAACAGGCTCAAGCTTCCCACGGGTTTGCTGT
TACCCTGGCCCCGACCTCTTCAGCGGCTCTGATTCAGCAATGTGCCAATGCCAACCAGCTTCGCCAGTTTGAGATGGCCT
TAGCCAGTTGCGAAAAAGCGTTCCAAGAAGGGGACGGAGACTGGGGAGAAGCAGGTTTAGAGTTTGCCTGGAGCCAACGG
GGAACAGCCCTGATTGGTCTGGGTCGGTTTGAAGAAGCGCTGACCTCCATTGATCGAGCGTTAGCCTTAACGCCAAAAGA
TGCCCATTCTTGGAGTGCAAGGGCCTTGTCTCTCTGGCGTCTAGGCCGATTTGATGAAGCCCTGGATGCTGCTGCCCAAG
GGGTAGACGTCGATCCGCAATCTTCTTTAGCTTGGTTTAACCAGGGCCGGATTCTGACGACTCTGGGCAAGTTAGAGGAA
GCTGTTGCGGCTTACGACCAGGCATTAAAAGGAGATGCCAATGCGGGGAAGCAGCCGACGCTAGTGGAGATCTGGATTAA
TCAAAGTGCAGCTTATTGGCGGCTGGAAGATTATGGTCAGGCCTTATCGGCTGCAGATCAGGCGGTGGCTCTGGATGCTA
AATCCGATCGCGCTTGGTATAACAAAGCCCTGGCTCTGATGGGGTTACGCTCCTATAGTCGGGCGGTGACGGCCTATAAT
AAAGCCCTTGCCTTTAACGAAAAAAATGCTGATTATTGGACCGGGAAAGGGATTGCCCTCAAGGCTTTAGGAAATTTTCC
TGAAGCCCTTGCCAGCTTAGAACAAGCCCTTAGTCTGAATCCCAACCATTCCCTAGCTTTGCTGAATCAAGAGCGGGTTA
AGAAGCAAATTGAGCCTTCCCAGTAG

Upstream 100 bases:

>100_bases
GCCATAATGCCTGATGGAACAACCCACTCCTGTCCTTAGGGAAAGAGTCTCAGTAGTTACTAGAAATCGGAATTGCCGAT
TGCGACGGTATAGATGGTCT

Downstream 100 bases:

>100_bases
GGGGTTAGGGTTTGCGGGCTGTGATCGCTTTGCGTGCGATCGCAAGTTCGTATTCACCATAGGTATTAGAAATCTGAACC
TGAAAGCCGATCTGTTTCAG

Product: TPR domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 541; Mature: 540

Protein sequence:

>541_residues
MGPLLWGLAFALLPLPLKAQEGLQDYDHWAGLCQSLTQQKQYEDALKACDQAIALNTNDPQTWIDRSTIVFALAKHSDAV
AAFNQVLKLKPDEPQILAKRCISLFKLKNYEPALKDCELALQVADQRGQSLPDQAWYYRSAALFKLERLEEALAAYDWAT
HIHSRDGRAWADRCQVLAALKQYSLAFQSCDRALRGDSDWGGSSPAIGWSQLAQLHRQLGDYNQALKGYDKALAFAPKDS
QLWSQQGILLDQLGEHQQAQASHGFAVTLAPTSSAALIQQCANANQLRQFEMALASCEKAFQEGDGDWGEAGLEFAWSQR
GTALIGLGRFEEALTSIDRALALTPKDAHSWSARALSLWRLGRFDEALDAAAQGVDVDPQSSLAWFNQGRILTTLGKLEE
AVAAYDQALKGDANAGKQPTLVEIWINQSAAYWRLEDYGQALSAADQAVALDAKSDRAWYNKALALMGLRSYSRAVTAYN
KALAFNEKNADYWTGKGIALKALGNFPEALASLEQALSLNPNHSLALLNQERVKKQIEPSQ

Sequences:

>Translated_541_residues
MGPLLWGLAFALLPLPLKAQEGLQDYDHWAGLCQSLTQQKQYEDALKACDQAIALNTNDPQTWIDRSTIVFALAKHSDAV
AAFNQVLKLKPDEPQILAKRCISLFKLKNYEPALKDCELALQVADQRGQSLPDQAWYYRSAALFKLERLEEALAAYDWAT
HIHSRDGRAWADRCQVLAALKQYSLAFQSCDRALRGDSDWGGSSPAIGWSQLAQLHRQLGDYNQALKGYDKALAFAPKDS
QLWSQQGILLDQLGEHQQAQASHGFAVTLAPTSSAALIQQCANANQLRQFEMALASCEKAFQEGDGDWGEAGLEFAWSQR
GTALIGLGRFEEALTSIDRALALTPKDAHSWSARALSLWRLGRFDEALDAAAQGVDVDPQSSLAWFNQGRILTTLGKLEE
AVAAYDQALKGDANAGKQPTLVEIWINQSAAYWRLEDYGQALSAADQAVALDAKSDRAWYNKALALMGLRSYSRAVTAYN
KALAFNEKNADYWTGKGIALKALGNFPEALASLEQALSLNPNHSLALLNQERVKKQIEPSQ
>Mature_540_residues
GPLLWGLAFALLPLPLKAQEGLQDYDHWAGLCQSLTQQKQYEDALKACDQAIALNTNDPQTWIDRSTIVFALAKHSDAVA
AFNQVLKLKPDEPQILAKRCISLFKLKNYEPALKDCELALQVADQRGQSLPDQAWYYRSAALFKLERLEEALAAYDWATH
IHSRDGRAWADRCQVLAALKQYSLAFQSCDRALRGDSDWGGSSPAIGWSQLAQLHRQLGDYNQALKGYDKALAFAPKDSQ
LWSQQGILLDQLGEHQQAQASHGFAVTLAPTSSAALIQQCANANQLRQFEMALASCEKAFQEGDGDWGEAGLEFAWSQRG
TALIGLGRFEEALTSIDRALALTPKDAHSWSARALSLWRLGRFDEALDAAAQGVDVDPQSSLAWFNQGRILTTLGKLEEA
VAAYDQALKGDANAGKQPTLVEIWINQSAAYWRLEDYGQALSAADQAVALDAKSDRAWYNKALALMGLRSYSRAVTAYNK
ALAFNEKNADYWTGKGIALKALGNFPEALASLEQALSLNPNHSLALLNQERVKKQIEPSQ

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 9 TPR repeats [H]

Homologues:

Organism=Homo sapiens, GI32307150, Length=395, Percent_Identity=24.3037974683544, Blast_Score=71, Evalue=3e-12,
Organism=Homo sapiens, GI32307148, Length=395, Percent_Identity=24.3037974683544, Blast_Score=70, Evalue=4e-12,
Organism=Homo sapiens, GI224809432, Length=218, Percent_Identity=28.4403669724771, Blast_Score=68, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI115532690, Length=433, Percent_Identity=23.7875288683603, Blast_Score=69, Evalue=5e-12,
Organism=Drosophila melanogaster, GI17647755, Length=395, Percent_Identity=24.5569620253165, Blast_Score=71, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24585827, Length=395, Percent_Identity=24.5569620253165, Blast_Score=71, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24585829, Length=395, Percent_Identity=24.5569620253165, Blast_Score=71, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008940
- InterPro:   IPR001440
- InterPro:   IPR013026
- InterPro:   IPR011990
- InterPro:   IPR019734 [H]

Pfam domain/function: PF00515 TPR_1 [H]

EC number: NA

Molecular weight: Translated: 59584; Mature: 59453

Theoretical pI: Translated: 5.51; Mature: 5.51

Prosite motif: PS50005 TPR L=RR ; PS50293 TPR_REGION

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
0.4 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGPLLWGLAFALLPLPLKAQEGLQDYDHWAGLCQSLTQQKQYEDALKACDQAIALNTNDP
CCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCC
QTWIDRSTIVFALAKHSDAVAAFNQVLKLKPDEPQILAKRCISLFKLKNYEPALKDCELA
HHHHCCHHEEEEEHHCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHH
LQVADQRGQSLPDQAWYYRSAALFKLERLEEALAAYDWATHIHSRDGRAWADRCQVLAAL
HHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
KQYSLAFQSCDRALRGDSDWGGSSPAIGWSQLAQLHRQLGDYNQALKGYDKALAFAPKDS
HHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCH
QLWSQQGILLDQLGEHQQAQASHGFAVTLAPTSSAALIQQCANANQLRQFEMALASCEKA
HHHHHCCCHHHHHCCHHHHHCCCCEEEEECCCCHHHHHHHHHCHHHHHHHHHHHHHHHHH
FQEGDGDWGEAGLEFAWSQRGTALIGLGRFEEALTSIDRALALTPKDAHSWSARALSLWR
HHCCCCCCCCHHHHHHHCCCCCEEEECHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHH
LGRFDEALDAAAQGVDVDPQSSLAWFNQGRILTTLGKLEEAVAAYDQALKGDANAGKQPT
HCCHHHHHHHHHCCCCCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
LVEIWINQSAAYWRLEDYGQALSAADQAVALDAKSDRAWYNKALALMGLRSYSRAVTAYN
EEEEEECCCCCEEEHHHHHHHHHHCCHHEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHH
KALAFNEKNADYWTGKGIALKALGNFPEALASLEQALSLNPNHSLALLNQERVKKQIEPS
HHHEECCCCCCEECCCCEEEEECCCCHHHHHHHHHHHCCCCCCCEEECCHHHHHHHCCCC
Q
C
>Mature Secondary Structure 
GPLLWGLAFALLPLPLKAQEGLQDYDHWAGLCQSLTQQKQYEDALKACDQAIALNTNDP
CHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCC
QTWIDRSTIVFALAKHSDAVAAFNQVLKLKPDEPQILAKRCISLFKLKNYEPALKDCELA
HHHHCCHHEEEEEHHCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHH
LQVADQRGQSLPDQAWYYRSAALFKLERLEEALAAYDWATHIHSRDGRAWADRCQVLAAL
HHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
KQYSLAFQSCDRALRGDSDWGGSSPAIGWSQLAQLHRQLGDYNQALKGYDKALAFAPKDS
HHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCH
QLWSQQGILLDQLGEHQQAQASHGFAVTLAPTSSAALIQQCANANQLRQFEMALASCEKA
HHHHHCCCHHHHHCCHHHHHCCCCEEEEECCCCHHHHHHHHHCHHHHHHHHHHHHHHHHH
FQEGDGDWGEAGLEFAWSQRGTALIGLGRFEEALTSIDRALALTPKDAHSWSARALSLWR
HHCCCCCCCCHHHHHHHCCCCCEEEECHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHH
LGRFDEALDAAAQGVDVDPQSSLAWFNQGRILTTLGKLEEAVAAYDQALKGDANAGKQPT
HCCHHHHHHHHHCCCCCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
LVEIWINQSAAYWRLEDYGQALSAADQAVALDAKSDRAWYNKALALMGLRSYSRAVTAYN
EEEEEECCCCCEEEHHHHHHHHHHCCHHEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHH
KALAFNEKNADYWTGKGIALKALGNFPEALASLEQALSLNPNHSLALLNQERVKKQIEPS
HHHEECCCCCCEECCCCEEEEECCCCHHHHHHHHHHHCCCCCCCEEECCHHHHHHHCCCC
Q
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087; 9697413 [H]