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The map label for this gene is folB [H]

Identifier: 158338028

GI number: 158338028

Start: 4961582

End: 4961941

Strand: Direct

Name: folB [H]

Synonym: AM1_4915

Alternate gene names: 158338028

Gene position: 4961582-4961941 (Clockwise)

Preceding gene: 158338026

Following gene: 158338029

Centisome position: 76.29

GC content: 47.22

Gene sequence:

>360_bases
ATGGATTGTATACACTTGAACGGCATCCGCAGCTACGGATACACAGGGTTTTTACCAGAAGAACAAGTTTTGGGGCAGTG
GTTTGAAGTTGATTTAGTCTTGTGGGTAAATTTAGCCGCGGCTGGTAGGAGCGATCGCATTGAAGATACGGTGGATTATC
GCCAAACTATTGAGCAGGTAAAACAGCTGATTCACCAGTCCAAATATGCGTTAATCGAGCGCCTAGCAACTGCCATCGCT
GAACAGCTACTGCACCACTCCAGCCTTGAAAAGGTCAGCGTCAAACTGACGAAAGTTGCTGCTCCTATTCCTGACTTTTC
GGGTCGTATCACCATCGAAATAACGCGAAACCGGTCTTGA

Upstream 100 bases:

>100_bases
GATTTGAGGTTAATTCGAGTAGTTATTTCTTAAGTTGATTATTCATCTATCAACTTTATGTCTATGAGGGACTATAATCC
ACAACTTTAGAGGTATCCGG

Downstream 100 bases:

>100_bases
GTAAAACTTTTCGCCCTGTTCATTTTTCTAGAAGAGGTCACCTCAAATCTAAGGGTGGCGAGCTATCTTTACCTTGAAGA
AATTGATACTATTGGCTACG

Product: dihydroneopterin aldolase

Products: NA

Alternate protein names: DHNA [H]

Number of amino acids: Translated: 119; Mature: 119

Protein sequence:

>119_residues
MDCIHLNGIRSYGYTGFLPEEQVLGQWFEVDLVLWVNLAAAGRSDRIEDTVDYRQTIEQVKQLIHQSKYALIERLATAIA
EQLLHHSSLEKVSVKLTKVAAPIPDFSGRITIEITRNRS

Sequences:

>Translated_119_residues
MDCIHLNGIRSYGYTGFLPEEQVLGQWFEVDLVLWVNLAAAGRSDRIEDTVDYRQTIEQVKQLIHQSKYALIERLATAIA
EQLLHHSSLEKVSVKLTKVAAPIPDFSGRITIEITRNRS
>Mature_119_residues
MDCIHLNGIRSYGYTGFLPEEQVLGQWFEVDLVLWVNLAAAGRSDRIEDTVDYRQTIEQVKQLIHQSKYALIERLATAIA
EQLLHHSSLEKVSVKLTKVAAPIPDFSGRITIEITRNRS

Specific function: Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin [H]

COG id: COG1539

COG function: function code H; Dihydroneopterin aldolase

Gene ontology:
GO:0004150: Dihydroneopterin aldolase
GO:0006760: Dihydroneopterin aldolase

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DHNA family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006156
- InterPro:   IPR006157 [H]

Pfam domain/function: PF02152 FolB [H]

EC number: =4.1.2.25 [H]

Molecular weight: Translated: 13536; Mature: 13536

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDCIHLNGIRSYGYTGFLPEEQVLGQWFEVDLVLWVNLAAAGRSDRIEDTVDYRQTIEQV
CCEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHEEHHHHCCCCCCCHHHHHHHHHHHHH
KQLIHQSKYALIERLATAIAEQLLHHSSLEKVSVKLTKVAAPIPDFSGRITIEITRNRS
HHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCEEEEEEECCCC
>Mature Secondary Structure
MDCIHLNGIRSYGYTGFLPEEQVLGQWFEVDLVLWVNLAAAGRSDRIEDTVDYRQTIEQV
CCEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHEEHHHHCCCCCCCHHHHHHHHHHHHH
KQLIHQSKYALIERLATAIAEQLLHHSSLEKVSVKLTKVAAPIPDFSGRITIEITRNRS
HHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCEEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]