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The map label for this gene is gpsA

Identifier: 158337882

GI number: 158337882

Start: 4809765

End: 4810697

Strand: Direct

Name: gpsA

Synonym: AM1_4768

Alternate gene names: 158337882

Gene position: 4809765-4810697 (Clockwise)

Preceding gene: 158337881

Following gene: 158337883

Centisome position: 73.95

GC content: 52.73

Gene sequence:

>933_bases
ATGTCCACAACAGCCATCACTATCTTGGGCACAGGGGTGTGGGGGTCTGCCTTAGGAACCCTAGCTCAAGCCAATCACCA
TACAGTGACGGCTTGGTCCCGCCGAGGACCGTTAACTTTGACCCAGAGCCTTGCCCAAGCCCAGGTGCTGGTGGTTGCCA
TCTCCATGAAGGGCATTCCTGACCTTGCAGCCCAACTGCAACAACTCAAGCTACCGACCTCAACCATTATCGTCAGTGCG
ACAAAAGGGTTAGATCCGGCGACCCTCCGCACACCTTCCCAAATTTGGCAGGCCACTTTCCCCAACAACCCTGTTTTGGT
TCTTTCGGGTCCCAATTTATCGAAAGAGATTGAGCAAAGGTTACCTGCTGCAACAGTGGTTGCAGGTCCTAATCAGGCTG
CCGTAGAAACGGTGCAACAGCTGTTTTCCTCTGACTGTTTTCGGGTCTATACCAACCCTGACCAGCTGGGGACTGAATTG
GGGGGGACCCTGAAGAACGTGATTGCGATCTCAGTCGGGGTTTGCGAAGGTCTTAAACTCGGCACCAATGCCCGTGCCGC
CCTGATTACCCGAGCGCTGCCAGAGATGATTCGAGTCGGCACCCATCTGGGCGGACAAGCCGAAACCTTTTTTGGGCTAT
CCGGCTTAGGAGATTTGTTAGCCACCTGTACCAGTCCCCTCAGCCGTAACTATCAAGTGGGATATCAACTGGCTCAAGGC
AAATCTCTACCTGAAATTTTGGATCAACTTCATGGCACCGCAGAAGGGGTGAATACCACCAATGTGCTGGTCGATTTGGC
CAATCGAGAAGGCATCCCCATTCCCATTGCCCGCCAAGTTCATCGACTTTTGAAGGGACGAATTACCCCCCAGGAAGCTT
TAGAAAGTTTGATGGATCGAGAATTAAAGCCGGAAGCTTGCGATTTGCTTTAG

Upstream 100 bases:

>100_bases
TATCATCGGTTTATGGAAGCCAATAGTTTGCCTGATTTTGTGACGGCTCAGACAACAGCGCCTATCCGTTGACGTTCTCT
CCAGTTAGGATTTTGCTTGC

Downstream 100 bases:

>100_bases
TGTGGCCCCAATCTATCCATTTCTTAGTATTGGCATCCCTTTAGGAGACTTACTGGATATAGGTTAGAGACTGTTGCAAC
TCCGTTGGACTCATAAAAAG

Product: NAD(P)H-dependent glycerol-3-phosphate dehydrogenase

Products: NA

Alternate protein names: NAD(P)H-dependent glycerol-3-phosphate dehydrogenase

Number of amino acids: Translated: 310; Mature: 309

Protein sequence:

>310_residues
MSTTAITILGTGVWGSALGTLAQANHHTVTAWSRRGPLTLTQSLAQAQVLVVAISMKGIPDLAAQLQQLKLPTSTIIVSA
TKGLDPATLRTPSQIWQATFPNNPVLVLSGPNLSKEIEQRLPAATVVAGPNQAAVETVQQLFSSDCFRVYTNPDQLGTEL
GGTLKNVIAISVGVCEGLKLGTNARAALITRALPEMIRVGTHLGGQAETFFGLSGLGDLLATCTSPLSRNYQVGYQLAQG
KSLPEILDQLHGTAEGVNTTNVLVDLANREGIPIPIARQVHRLLKGRITPQEALESLMDRELKPEACDLL

Sequences:

>Translated_310_residues
MSTTAITILGTGVWGSALGTLAQANHHTVTAWSRRGPLTLTQSLAQAQVLVVAISMKGIPDLAAQLQQLKLPTSTIIVSA
TKGLDPATLRTPSQIWQATFPNNPVLVLSGPNLSKEIEQRLPAATVVAGPNQAAVETVQQLFSSDCFRVYTNPDQLGTEL
GGTLKNVIAISVGVCEGLKLGTNARAALITRALPEMIRVGTHLGGQAETFFGLSGLGDLLATCTSPLSRNYQVGYQLAQG
KSLPEILDQLHGTAEGVNTTNVLVDLANREGIPIPIARQVHRLLKGRITPQEALESLMDRELKPEACDLL
>Mature_309_residues
STTAITILGTGVWGSALGTLAQANHHTVTAWSRRGPLTLTQSLAQAQVLVVAISMKGIPDLAAQLQQLKLPTSTIIVSAT
KGLDPATLRTPSQIWQATFPNNPVLVLSGPNLSKEIEQRLPAATVVAGPNQAAVETVQQLFSSDCFRVYTNPDQLGTELG
GTLKNVIAISVGVCEGLKLGTNARAALITRALPEMIRVGTHLGGQAETFFGLSGLGDLLATCTSPLSRNYQVGYQLAQGK
SLPEILDQLHGTAEGVNTTNVLVDLANREGIPIPIARQVHRLLKGRITPQEALESLMDRELKPEACDLL

Specific function: De novo phospholipid biosynthesis; glycerol-3 phosphate formation. [C]

COG id: COG0240

COG function: function code C; Glycerol-3-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family

Homologues:

Organism=Homo sapiens, GI33695088, Length=295, Percent_Identity=24.406779661017, Blast_Score=79, Evalue=5e-15,
Organism=Homo sapiens, GI24307999, Length=218, Percent_Identity=27.5229357798165, Blast_Score=77, Evalue=2e-14,
Organism=Escherichia coli, GI1790037, Length=330, Percent_Identity=33.6363636363636, Blast_Score=174, Evalue=5e-45,
Organism=Caenorhabditis elegans, GI32564399, Length=351, Percent_Identity=25.6410256410256, Blast_Score=89, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI193210134, Length=318, Percent_Identity=26.1006289308176, Blast_Score=88, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI193210136, Length=360, Percent_Identity=25, Blast_Score=86, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI32564403, Length=360, Percent_Identity=25, Blast_Score=85, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI17507425, Length=350, Percent_Identity=24, Blast_Score=80, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6324513, Length=228, Percent_Identity=28.9473684210526, Blast_Score=68, Evalue=2e-12,
Organism=Drosophila melanogaster, GI17136200, Length=355, Percent_Identity=24.7887323943662, Blast_Score=92, Evalue=3e-19,
Organism=Drosophila melanogaster, GI17136202, Length=347, Percent_Identity=24.4956772334294, Blast_Score=92, Evalue=5e-19,
Organism=Drosophila melanogaster, GI17136204, Length=347, Percent_Identity=24.4956772334294, Blast_Score=92, Evalue=5e-19,
Organism=Drosophila melanogaster, GI22026922, Length=201, Percent_Identity=27.363184079602, Blast_Score=75, Evalue=5e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GPDA_ACAM1 (B0C2F0)

Other databases:

- EMBL:   CP000828
- RefSeq:   YP_001519058.1
- ProteinModelPortal:   B0C2F0
- SMR:   B0C2F0
- GeneID:   5683568
- GenomeReviews:   CP000828_GR
- KEGG:   amr:AM1_4768
- HOGENOM:   HBG586392
- OMA:   NYRVGYG
- ProtClustDB:   PRK14619
- BioCyc:   AMAR329726:AM1_4768-MONOMER
- HAMAP:   MF_00394
- InterPro:   IPR008927
- InterPro:   IPR013328
- InterPro:   IPR006168
- InterPro:   IPR006109
- InterPro:   IPR011128
- InterPro:   IPR016040
- Gene3D:   G3DSA:3.40.50.720
- Gene3D:   G3DSA:1.10.1040.10
- PANTHER:   PTHR11728
- PIRSF:   PIRSF000114

Pfam domain/function: PF07479 NAD_Gly3P_dh_C; PF01210 NAD_Gly3P_dh_N; SSF48179 6DGDH_C_like

EC number: =1.1.1.94

Molecular weight: Translated: 32845; Mature: 32714

Theoretical pI: Translated: 7.51; Mature: 7.51

Prosite motif: PS00957 NAD_G3PDH

Important sites: ACT_SITE 165-165 BINDING 82-82 BINDING 82-82 BINDING 114-114 BINDING 229-229 BINDING 255-255

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTTAITILGTGVWGSALGTLAQANHHTVTAWSRRGPLTLTQSLAQAQVLVVAISMKGIP
CCCEEEEEEECCHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHEEEEEEEECCCCH
DLAAQLQQLKLPTSTIIVSATKGLDPATLRTPSQIWQATFPNNPVLVLSGPNLSKEIEQR
HHHHHHHHHCCCCCEEEEEECCCCCCHHCCCHHHHHHHCCCCCCEEEEECCCHHHHHHHH
LPAATVVAGPNQAAVETVQQLFSSDCFRVYTNPDQLGTELGGTLKNVIAISVGVCEGLKL
CCCEEEEECCCHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCC
GTNARAALITRALPEMIRVGTHLGGQAETFFGLSGLGDLLATCTSPLSRNYQVGYQLAQG
CCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHCHHHHHHHHHHHHHHHCCCHHHCEEECCC
KSLPEILDQLHGTAEGVNTTNVLVDLANREGIPIPIARQVHRLLKGRITPQEALESLMDR
CCHHHHHHHHCCCCCCCCHHHHEEEECCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHCC
ELKPEACDLL
CCCCHHHCCC
>Mature Secondary Structure 
STTAITILGTGVWGSALGTLAQANHHTVTAWSRRGPLTLTQSLAQAQVLVVAISMKGIP
CCEEEEEEECCHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHEEEEEEEECCCCH
DLAAQLQQLKLPTSTIIVSATKGLDPATLRTPSQIWQATFPNNPVLVLSGPNLSKEIEQR
HHHHHHHHHCCCCCEEEEEECCCCCCHHCCCHHHHHHHCCCCCCEEEEECCCHHHHHHHH
LPAATVVAGPNQAAVETVQQLFSSDCFRVYTNPDQLGTELGGTLKNVIAISVGVCEGLKL
CCCEEEEECCCHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCC
GTNARAALITRALPEMIRVGTHLGGQAETFFGLSGLGDLLATCTSPLSRNYQVGYQLAQG
CCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHCHHHHHHHHHHHHHHHCCCHHHCEEECCC
KSLPEILDQLHGTAEGVNTTNVLVDLANREGIPIPIARQVHRLLKGRITPQEALESLMDR
CCHHHHHHHHCCCCCCCCHHHHEEEECCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHCC
ELKPEACDLL
CCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA