Click here to switch to the map view.

The map label for this gene is glpD [H]

Identifier: 158337881

GI number: 158337881

Start: 4808054

End: 4809736

Strand: Direct

Name: glpD [H]

Synonym: AM1_4767

Alternate gene names: 158337881

Gene position: 4808054-4809736 (Clockwise)

Preceding gene: 158337879

Following gene: 158337882

Centisome position: 73.93

GC content: 50.09

Gene sequence:

>1683_bases
ATGTGCTCACACATGAGAAATTGGCAAACGATTGAGAACACGGCCTTTGACCTCATCGTGATTGGGGGAGGCAGTAATGG
AGCAGGGGTGGCCCGTGATGCGGCTCTGCGAGGCCTTAAAACTCTGCTGATCGATAAAGATGATTTCGGCAGCGGCACCA
CAGGCTGGTCGAGCCGGTTGATTCATGGCGGGCTGCGCTATCTGGAATACTTTGAATTCAACCTGGTCCGGGAATCCTTG
CGAGAGCGGGAAGTGCTATTACGGGTGGCCCCCCATTTAGTCCGGCCTCTACAGATGTCGATTCCCGTCTATGCCAGCGG
CTCGCGAGCTTTCTGGGAAATTCAGGCCGGAATGCTGCTCTATGATGTTCTCAGTTTTGATAAATCCCTACCCAATCACC
GGATTTTGCCTCTGCAAAAGTGCTTGCAGCTATTTCGGCACCTGAATCCAAAAGGGTTAAAAGGGGCAGCCCAATATTTT
GATGCCCAAGTCGTTCATGCTGAGCGCCTCTGTTTGGAATTAGTGCTGTCGGCCCAAACTGCAGGGGCGACAACCCTGAA
CTATGCCCAAGTGTCTCAGCTTCAAGTCGAAGGAGATCGAGTCACAGGCATTACTCTTGACGACTTGATTGCAGAGACCA
CCCATACAGTCCAACTATCCCCCCAAACCGTGGTGATTAATACGGCAGGTCCCTGGGTCGATCAGGTTTTACAAGGGATA
CAGTCTCCAACCCCGAAACAAGAGCGAAAAATCGGCGGTACTAAAGGCAGCCATATTATCGTCGATCCCTTTCCCGGAGC
CCCCGACGCTGCCCTTTATGCGGAAGCCGAAGTCGATAACCGTCCCTTTTTCATTCTGCCCTGGGCCAATCAATATCTGA
TTGGGACTACAGATATTCGGTATAGCGGTGATTTAGATCGGGTTAAGGCCGATGACGCTGAAATTGATTATTTGCTGAAT
GAAACCAATCGAGTGATTCCCTGTGCCCAACTGTCTCGGGCTGATATTCGCTTTACCTATGCCGGTGTCCGACCGCTCCC
CTATAGCGAAGGGAAAAAGACCAGCAGTATTACCCGCAGCCATGTTCTCTACGATCACTGCAAAGACGGCATTACCAATT
TAATTTCTTTAATTGGCGGTAAGCTTACCACCTATCGGCAGGTGGCAGAAGAAATGGTGGATGCTGTGTTGAAGAAGCAA
GGTCGCGGCCCAATTCCTTGTGTAACCAAGCAAGAGCTATTTCCAGGTGCGATCTCACTCAACGATACCTTGATCGAAAC
CATGATCAGCAAATACCAGTCCCTCGTTAGCCGAGAGACTGTCTTTCATCTGTTCTCTATCTATGGCAGTTTTGCTGTGA
AGATTTTGGCTCTTATTGATGAAACCCCAGAACTAGCCGAGCCGATTACCCCATCCCTACTCGATATTAAGGCCCAAGTG
GTCTATGCGGTCCAATCTGAACACGCCCACACCCTCGTCGATATATGCGTGCGGCGAACGATTTTGGCGATGCAAACCAA
TTATGGTTTTGATGTGCTGCCAGCAGTGACGGCAATTTTGAAGCAATACTGCAACTGGAGTGACGCAGATTGTGATCACC
ACATCCAACACTATCATCGGTTTATGGAAGCCAATAGTTTGCCTGATTTTGTGACGGCTCAGACAACAGCGCCTATCCGT
TGA

Upstream 100 bases:

>100_bases
GTGAAAGAGATGAAGAAAACGCCTTAAATTAGAGATCTATGTCATCTTGTTGGCAGTGCCACAGCCCAAAATCCTGGGTT
CAAATGTAAATCACAACAGA

Downstream 100 bases:

>100_bases
CGTTCTCTCCAGTTAGGATTTTGCTTGCATGTCCACAACAGCCATCACTATCTTGGGCACAGGGGTGTGGGGGTCTGCCT
TAGGAACCCTAGCTCAAGCC

Product: glycerol-3-phosphate dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 560; Mature: 560

Protein sequence:

>560_residues
MCSHMRNWQTIENTAFDLIVIGGGSNGAGVARDAALRGLKTLLIDKDDFGSGTTGWSSRLIHGGLRYLEYFEFNLVRESL
REREVLLRVAPHLVRPLQMSIPVYASGSRAFWEIQAGMLLYDVLSFDKSLPNHRILPLQKCLQLFRHLNPKGLKGAAQYF
DAQVVHAERLCLELVLSAQTAGATTLNYAQVSQLQVEGDRVTGITLDDLIAETTHTVQLSPQTVVINTAGPWVDQVLQGI
QSPTPKQERKIGGTKGSHIIVDPFPGAPDAALYAEAEVDNRPFFILPWANQYLIGTTDIRYSGDLDRVKADDAEIDYLLN
ETNRVIPCAQLSRADIRFTYAGVRPLPYSEGKKTSSITRSHVLYDHCKDGITNLISLIGGKLTTYRQVAEEMVDAVLKKQ
GRGPIPCVTKQELFPGAISLNDTLIETMISKYQSLVSRETVFHLFSIYGSFAVKILALIDETPELAEPITPSLLDIKAQV
VYAVQSEHAHTLVDICVRRTILAMQTNYGFDVLPAVTAILKQYCNWSDADCDHHIQHYHRFMEANSLPDFVTAQTTAPIR

Sequences:

>Translated_560_residues
MCSHMRNWQTIENTAFDLIVIGGGSNGAGVARDAALRGLKTLLIDKDDFGSGTTGWSSRLIHGGLRYLEYFEFNLVRESL
REREVLLRVAPHLVRPLQMSIPVYASGSRAFWEIQAGMLLYDVLSFDKSLPNHRILPLQKCLQLFRHLNPKGLKGAAQYF
DAQVVHAERLCLELVLSAQTAGATTLNYAQVSQLQVEGDRVTGITLDDLIAETTHTVQLSPQTVVINTAGPWVDQVLQGI
QSPTPKQERKIGGTKGSHIIVDPFPGAPDAALYAEAEVDNRPFFILPWANQYLIGTTDIRYSGDLDRVKADDAEIDYLLN
ETNRVIPCAQLSRADIRFTYAGVRPLPYSEGKKTSSITRSHVLYDHCKDGITNLISLIGGKLTTYRQVAEEMVDAVLKKQ
GRGPIPCVTKQELFPGAISLNDTLIETMISKYQSLVSRETVFHLFSIYGSFAVKILALIDETPELAEPITPSLLDIKAQV
VYAVQSEHAHTLVDICVRRTILAMQTNYGFDVLPAVTAILKQYCNWSDADCDHHIQHYHRFMEANSLPDFVTAQTTAPIR
>Mature_560_residues
MCSHMRNWQTIENTAFDLIVIGGGSNGAGVARDAALRGLKTLLIDKDDFGSGTTGWSSRLIHGGLRYLEYFEFNLVRESL
REREVLLRVAPHLVRPLQMSIPVYASGSRAFWEIQAGMLLYDVLSFDKSLPNHRILPLQKCLQLFRHLNPKGLKGAAQYF
DAQVVHAERLCLELVLSAQTAGATTLNYAQVSQLQVEGDRVTGITLDDLIAETTHTVQLSPQTVVINTAGPWVDQVLQGI
QSPTPKQERKIGGTKGSHIIVDPFPGAPDAALYAEAEVDNRPFFILPWANQYLIGTTDIRYSGDLDRVKADDAEIDYLLN
ETNRVIPCAQLSRADIRFTYAGVRPLPYSEGKKTSSITRSHVLYDHCKDGITNLISLIGGKLTTYRQVAEEMVDAVLKKQ
GRGPIPCVTKQELFPGAISLNDTLIETMISKYQSLVSRETVFHLFSIYGSFAVKILALIDETPELAEPITPSLLDIKAQV
VYAVQSEHAHTLVDICVRRTILAMQTNYGFDVLPAVTAILKQYCNWSDADCDHHIQHYHRFMEANSLPDFVTAQTTAPIR

Specific function: Conversion Of Glycerol 3-Phosphate To Dihydroxyacetone. Uses Molecular Oxygen Or Nitrate As Electron Acceptor. [C]

COG id: COG0578

COG function: function code C; Glycerol-3-phosphate dehydrogenase

Gene ontology:
GO:0004368: Glycerol-3-phosphate dehydrogenase
GO:0006072: Glycerol-3-phosphate dehydrogenase
GO:0009331: Glycerol-3-phosphate dehydrogenase
GO:0016491: Glycerol-3-phosphate dehydrogenase
GO:0055114: Glycerol-3-phosphate dehydrogenase

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI285002233, Length=564, Percent_Identity=31.2056737588652, Blast_Score=242, Evalue=6e-64,
Organism=Homo sapiens, GI285002231, Length=564, Percent_Identity=31.2056737588652, Blast_Score=242, Evalue=6e-64,
Organism=Escherichia coli, GI2367226, Length=472, Percent_Identity=33.4745762711864, Blast_Score=208, Evalue=9e-55,
Organism=Escherichia coli, GI1788574, Length=497, Percent_Identity=26.9617706237425, Blast_Score=124, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI17509253, Length=549, Percent_Identity=32.6047358834244, Blast_Score=221, Evalue=6e-58,
Organism=Caenorhabditis elegans, GI115534726, Length=549, Percent_Identity=30.6010928961749, Blast_Score=211, Evalue=7e-55,
Organism=Saccharomyces cerevisiae, GI6322036, Length=593, Percent_Identity=29.8482293423271, Blast_Score=191, Evalue=3e-49,
Organism=Drosophila melanogaster, GI161077125, Length=571, Percent_Identity=31.6987740805604, Blast_Score=226, Evalue=2e-59,
Organism=Drosophila melanogaster, GI24653942, Length=571, Percent_Identity=31.6987740805604, Blast_Score=226, Evalue=2e-59,
Organism=Drosophila melanogaster, GI24653944, Length=571, Percent_Identity=31.6987740805604, Blast_Score=226, Evalue=2e-59,
Organism=Drosophila melanogaster, GI20130025, Length=571, Percent_Identity=31.6987740805604, Blast_Score=226, Evalue=2e-59,
Organism=Drosophila melanogaster, GI24586295, Length=573, Percent_Identity=27.7486910994764, Blast_Score=173, Evalue=2e-43,
Organism=Drosophila melanogaster, GI19921278, Length=554, Percent_Identity=26.7148014440433, Blast_Score=147, Evalue=2e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006076
- InterPro:   IPR000447 [H]

Pfam domain/function: PF01266 DAO [H]

EC number: =1.1.5.3 [H]

Molecular weight: Translated: 62250; Mature: 62250

Theoretical pI: Translated: 6.46; Mature: 6.46

Prosite motif: PS00977 FAD_G3PDH_1 ; PS00978 FAD_G3PDH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCSHMRNWQTIENTAFDLIVIGGGSNGAGVARDAALRGLKTLLIDKDDFGSGTTGWSSRL
CCCCCCCCCHHCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHEECCCCCCCCCCCHHHHH
IHGGLRYLEYFEFNLVRESLREREVLLRVAPHLVRPLQMSIPVYASGSRAFWEIQAGMLL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCEEECCCCEEEEECCCHHH
YDVLSFDKSLPNHRILPLQKCLQLFRHLNPKGLKGAAQYFDAQVVHAERLCLELVLSAQT
HHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCC
AGATTLNYAQVSQLQVEGDRVTGITLDDLIAETTHTVQLSPQTVVINTAGPWVDQVLQGI
CCCCEECHHHHHEEEECCCEEECEEHHHHHHCCCCEEEECCCEEEEECCCHHHHHHHHHH
QSPTPKQERKIGGTKGSHIIVDPFPGAPDAALYAEAEVDNRPFFILPWANQYLIGTTDIR
CCCCCHHHHHCCCCCCCEEEEECCCCCCCCEEEEEEECCCCCEEEEECCCCEEEECCCEE
YSGDLDRVKADDAEIDYLLNETNRVIPCAQLSRADIRFTYAGVRPLPYSEGKKTSSITRS
ECCCCCCCCCCCCHHHHHCCCCCCEECHHHCCCCCEEEEEECCCCCCCCCCCCHHHHHHH
HVLYDHCKDGITNLISLIGGKLTTYRQVAEEMVDAVLKKQGRGPIPCVTKQELFPGAISL
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHCCCCCCCC
NDTLIETMISKYQSLVSRETVFHLFSIYGSFAVKILALIDETPELAEPITPSLLDIKAQV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCHHHHHHHHE
VYAVQSEHAHTLVDICVRRTILAMQTNYGFDVLPAVTAILKQYCNWSDADCDHHIQHYHR
EEEECCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHH
FMEANSLPDFVTAQTTAPIR
HHHHCCCCCCEECCCCCCCC
>Mature Secondary Structure
MCSHMRNWQTIENTAFDLIVIGGGSNGAGVARDAALRGLKTLLIDKDDFGSGTTGWSSRL
CCCCCCCCCHHCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHEECCCCCCCCCCCHHHHH
IHGGLRYLEYFEFNLVRESLREREVLLRVAPHLVRPLQMSIPVYASGSRAFWEIQAGMLL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCEEECCCCEEEEECCCHHH
YDVLSFDKSLPNHRILPLQKCLQLFRHLNPKGLKGAAQYFDAQVVHAERLCLELVLSAQT
HHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCC
AGATTLNYAQVSQLQVEGDRVTGITLDDLIAETTHTVQLSPQTVVINTAGPWVDQVLQGI
CCCCEECHHHHHEEEECCCEEECEEHHHHHHCCCCEEEECCCEEEEECCCHHHHHHHHHH
QSPTPKQERKIGGTKGSHIIVDPFPGAPDAALYAEAEVDNRPFFILPWANQYLIGTTDIR
CCCCCHHHHHCCCCCCCEEEEECCCCCCCCEEEEEEECCCCCEEEEECCCCEEEECCCEE
YSGDLDRVKADDAEIDYLLNETNRVIPCAQLSRADIRFTYAGVRPLPYSEGKKTSSITRS
ECCCCCCCCCCCCHHHHHCCCCCCEECHHHCCCCCEEEEEECCCCCCCCCCCCHHHHHHH
HVLYDHCKDGITNLISLIGGKLTTYRQVAEEMVDAVLKKQGRGPIPCVTKQELFPGAISL
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHCCCCCCCC
NDTLIETMISKYQSLVSRETVFHLFSIYGSFAVKILALIDETPELAEPITPSLLDIKAQV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCHHHHHHHHE
VYAVQSEHAHTLVDICVRRTILAMQTNYGFDVLPAVTAILKQYCNWSDADCDHHIQHYHR
EEEECCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHH
FMEANSLPDFVTAQTTAPIR
HHHHCCCCCCEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]