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The map label for this gene is bla [H]

Identifier: 158337427

GI number: 158337427

Start: 4326731

End: 4327456

Strand: Direct

Name: bla [H]

Synonym: AM1_4306

Alternate gene names: 158337427

Gene position: 4326731-4327456 (Clockwise)

Preceding gene: 158337426

Following gene: 158337434

Centisome position: 66.53

GC content: 49.31

Gene sequence:

>726_bases
TTGGCTCAGCAGACGGTTTCCCTGGCCCAGCCTTTTCAAGATCTCAAGGTCAACGGCTCGATTTTGATTTACGACCTCAA
ACGCAACCGCACCTATCAGCACAATCCGGCTCGCAATACCCAGCCGTTTTTACCTGCATCCACCTTTAAGATCCTCAACT
CCCTGATTGCCCTAGAAACAGGGGTGATTGCTAATGACCTTGCTATTCTGACCTGGGATGGGGTGGAACGCAGTTTCCCC
ACTTGGAATCGAGACCTGAATTTGCAAACCGCGTTTAAGGTATCGGCAGTCTGGTTCTACCAGGTATTAGCGCGTCGCAT
TGGCTTTCAGCGGATGCAGCAATGGGTGACTAAAGTCGGCTACGGCAATCAATCCATTGGCAAGGCCGATGAGATAGATA
CCTTTTGGCTGACGGGAGATTTACGGATTTCACCGACGGAACAGATTCAGTTCCTCCAGCGGTTGTATCGCAATGAACTC
CCTTTTTCAGAATCTGCGATCGCAACGGTGAAACAGATCATGATTGTGGAGCAAACACCTGAGTACACCATCCGAGCGAA
GACGGGTTGGGCACTTCAGCCTGGCATTGGTTGGTATGTGGGTTATGTCGAGCAAAATGACAATGTCTATTTCTTTGCCA
CCAATCTCGATATCGGTGATCAGAAAGATTTACCCGCTCGGGCAGAAGTAACGCGTCGCAGTTTGAAAGCTTTAAATCTG
TTGTAG

Upstream 100 bases:

>100_bases
TAAAAAGTTGGGGTACAGGGTTGCCCGGTGTTTGGCGATCGCAAGTCTATCTGTAACCGCCATCCCCTGGGGCGAACTAT
CTGTTGCAGCCACTCCCCAA

Downstream 100 bases:

>100_bases
ATGAATTGTCATTCGTTTGATCCGATCCATCCTGTGTTGTCATCAGCATTAATCGTGAGAGTTTAAAGCTAGCAATTAGT
CTGTATTGTCCACGAGAACG

Product: beta-lactamase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 241; Mature: 240

Protein sequence:

>241_residues
MAQQTVSLAQPFQDLKVNGSILIYDLKRNRTYQHNPARNTQPFLPASTFKILNSLIALETGVIANDLAILTWDGVERSFP
TWNRDLNLQTAFKVSAVWFYQVLARRIGFQRMQQWVTKVGYGNQSIGKADEIDTFWLTGDLRISPTEQIQFLQRLYRNEL
PFSESAIATVKQIMIVEQTPEYTIRAKTGWALQPGIGWYVGYVEQNDNVYFFATNLDIGDQKDLPARAEVTRRSLKALNL
L

Sequences:

>Translated_241_residues
MAQQTVSLAQPFQDLKVNGSILIYDLKRNRTYQHNPARNTQPFLPASTFKILNSLIALETGVIANDLAILTWDGVERSFP
TWNRDLNLQTAFKVSAVWFYQVLARRIGFQRMQQWVTKVGYGNQSIGKADEIDTFWLTGDLRISPTEQIQFLQRLYRNEL
PFSESAIATVKQIMIVEQTPEYTIRAKTGWALQPGIGWYVGYVEQNDNVYFFATNLDIGDQKDLPARAEVTRRSLKALNL
L
>Mature_240_residues
AQQTVSLAQPFQDLKVNGSILIYDLKRNRTYQHNPARNTQPFLPASTFKILNSLIALETGVIANDLAILTWDGVERSFPT
WNRDLNLQTAFKVSAVWFYQVLARRIGFQRMQQWVTKVGYGNQSIGKADEIDTFWLTGDLRISPTEQIQFLQRLYRNELP
FSESAIATVKQIMIVEQTPEYTIRAKTGWALQPGIGWYVGYVEQNDNVYFFATNLDIGDQKDLPARAEVTRRSLKALNLL

Specific function: Hydrolyzes both oxacillin and methicillin [H]

COG id: COG2602

COG function: function code V; Beta-lactamase class D

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-D beta-lactamase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR002137
- InterPro:   IPR001460 [H]

Pfam domain/function: PF00905 Transpeptidase [H]

EC number: =3.5.2.6 [H]

Molecular weight: Translated: 27625; Mature: 27494

Theoretical pI: Translated: 9.46; Mature: 9.46

Prosite motif: PS00337 BETA_LACTAMASE_D

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
0.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAQQTVSLAQPFQDLKVNGSILIYDLKRNRTYQHNPARNTQPFLPASTFKILNSLIALET
CCCCHHHHHCCHHHHCCCCCEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHC
GVIANDLAILTWDGVERSFPTWNRDLNLQTAFKVSAVWFYQVLARRIGFQRMQQWVTKVG
CCEECCEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
YGNQSIGKADEIDTFWLTGDLRISPTEQIQFLQRLYRNELPFSESAIATVKQIMIVEQTP
CCCCCCCCCCCCCEEEEECCEEECCHHHHHHHHHHHHCCCCCCHHHHHHHHHHEEEECCC
EYTIRAKTGWALQPGIGWYVGYVEQNDNVYFFATNLDIGDQKDLPARAEVTRRSLKALNL
CEEEEECCCCEECCCCCEEEEEEEECCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHCC
L
C
>Mature Secondary Structure 
AQQTVSLAQPFQDLKVNGSILIYDLKRNRTYQHNPARNTQPFLPASTFKILNSLIALET
CCCHHHHHCCHHHHCCCCCEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHC
GVIANDLAILTWDGVERSFPTWNRDLNLQTAFKVSAVWFYQVLARRIGFQRMQQWVTKVG
CCEECCEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
YGNQSIGKADEIDTFWLTGDLRISPTEQIQFLQRLYRNELPFSESAIATVKQIMIVEQTP
CCCCCCCCCCCCCEEEEECCEEECCHHHHHHHHHHHHCCCCCCHHHHHHHHHHEEEECCC
EYTIRAKTGWALQPGIGWYVGYVEQNDNVYFFATNLDIGDQKDLPARAEVTRRSLKALNL
CEEEEECCCCEECCCCCEEEEEEEECCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHCC
L
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1495394 [H]