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The map label for this gene is dapL [H]

Identifier: 158337123

GI number: 158337123

Start: 4044691

End: 4045860

Strand: Reverse

Name: dapL [H]

Synonym: AM1_3997

Alternate gene names: 158337123

Gene position: 4045860-4044691 (Counterclockwise)

Preceding gene: 158337125

Following gene: 158337122

Centisome position: 62.21

GC content: 50.09

Gene sequence:

>1170_bases
ATGAAATTTGCCGATCGCATTCAACGATTCCAAGCCAATGTCTTTGCGGACATGGATCAGGCTAAGCGCCAAGCCCTTGA
TACCGGTCAATCTTTGATTGACTTGTCCTTGGGATCTTCAGATTTGCCTGTTGCTGCGCCGATTTTGGAGACGATTAGCC
AGTCATTACAAGACCCATCGACCCATGGGTATTTGCTCTTTCATGGCACCCGCTCTTTTCGAGAGGCAGTCGCGGCCTGG
TATGAGCAGCGGTTTGGGCTATCCGTCGATCCAGAAACGGAGGTATTGCCTCTAATTGGATCCCAAGAAGGAACGGCTCA
TTTACCCCTTGCCATTCTCAATCCTGGTGATATTGCCTTACTGCAAGATCCGGGCTATCCCTCCCACGCGGGCGGGGTCT
ATCTAGCAGGCGGGGAAATGTATGGCATGCCCCTATTAGCTGAAAATCAATTTCTTCCAGTATTTAGCGAGATCCCAACT
GAGGTGCGACAGAAGGCCCGGATGATGGTGCTCAGCTATCCCCACAATCCCACTACTGCGATCGCACCCCTGTCTTTCTT
CCAGGAAGCCGTTCAATTTTGCCAAGACCATGACTTAGTCCTCGTTCACGACTTCCCCTACGTTGACTTTGTCTTCTCGG
AGCAAAAAATGCCGTCGATCCTGCAAGCCGATCGCCATCGGCAGTGCTCCATCGAATTTTTTACGTTTTCCAAGTCCTAC
AGCATGGGAGGCTTTCGAATTGGGTTTGCCGTTGGCAATGCCGACCTCATTACCAGTTTGAGAAAAATTAAAGCCATTGT
CGATTTCAACCAATATCTGGGCATTTTAAATGGTGCCGTTACGGCTCTCAAGACAAGTGATGCTGAACTGCAACAGACCT
TATCCATTTTTCAAAAACGTCGCGATGTTTTTGTCACGGCCCTAGCCAAGATAGGTTGGGTCATCCCCAAACCCACGGCC
ACCATGTACATTTGGGCACCTTTACCGGAACCTTGGCAACAACAATCAGTCGAATTCTGTAAGCAGCTCGTCCTTCAAAC
GGGTGTCGCTGCCTCACCAGGAGCCGGTTTTGGTCCAGCAGGAGAAGGATATGTGCGCTTTGCCTTAGTCCAAGATCCTG
ACACGCTAAACACAGCCGTTGACCGAATCGATTCCTTCCTGCATACTTGA

Upstream 100 bases:

>100_bases
ACAAGCGTCCCATACCAACGGATTACCCCGGAAGCTAGTCATCAGTTAACCTCATTTTGGGCAGATCTAAGGTTGTCTTA
GATCTGCAATGTTTTAGCGG

Downstream 100 bases:

>100_bases
CCATGCAGAAAGGGCAGTCCTGTATTAATCCGACTTGATTTAGATATACTCCCCTCACAGCAAAGGAAATCAGTCTTTAT
GAGTTATTCTCGCCGTTTAC

Product: succinyldiaminopimelate transaminase

Products: NA

Alternate protein names: DAP-AT; DAP-aminotransferase; LL-DAP-aminotransferase [H]

Number of amino acids: Translated: 389; Mature: 389

Protein sequence:

>389_residues
MKFADRIQRFQANVFADMDQAKRQALDTGQSLIDLSLGSSDLPVAAPILETISQSLQDPSTHGYLLFHGTRSFREAVAAW
YEQRFGLSVDPETEVLPLIGSQEGTAHLPLAILNPGDIALLQDPGYPSHAGGVYLAGGEMYGMPLLAENQFLPVFSEIPT
EVRQKARMMVLSYPHNPTTAIAPLSFFQEAVQFCQDHDLVLVHDFPYVDFVFSEQKMPSILQADRHRQCSIEFFTFSKSY
SMGGFRIGFAVGNADLITSLRKIKAIVDFNQYLGILNGAVTALKTSDAELQQTLSIFQKRRDVFVTALAKIGWVIPKPTA
TMYIWAPLPEPWQQQSVEFCKQLVLQTGVAASPGAGFGPAGEGYVRFALVQDPDTLNTAVDRIDSFLHT

Sequences:

>Translated_389_residues
MKFADRIQRFQANVFADMDQAKRQALDTGQSLIDLSLGSSDLPVAAPILETISQSLQDPSTHGYLLFHGTRSFREAVAAW
YEQRFGLSVDPETEVLPLIGSQEGTAHLPLAILNPGDIALLQDPGYPSHAGGVYLAGGEMYGMPLLAENQFLPVFSEIPT
EVRQKARMMVLSYPHNPTTAIAPLSFFQEAVQFCQDHDLVLVHDFPYVDFVFSEQKMPSILQADRHRQCSIEFFTFSKSY
SMGGFRIGFAVGNADLITSLRKIKAIVDFNQYLGILNGAVTALKTSDAELQQTLSIFQKRRDVFVTALAKIGWVIPKPTA
TMYIWAPLPEPWQQQSVEFCKQLVLQTGVAASPGAGFGPAGEGYVRFALVQDPDTLNTAVDRIDSFLHT
>Mature_389_residues
MKFADRIQRFQANVFADMDQAKRQALDTGQSLIDLSLGSSDLPVAAPILETISQSLQDPSTHGYLLFHGTRSFREAVAAW
YEQRFGLSVDPETEVLPLIGSQEGTAHLPLAILNPGDIALLQDPGYPSHAGGVYLAGGEMYGMPLLAENQFLPVFSEIPT
EVRQKARMMVLSYPHNPTTAIAPLSFFQEAVQFCQDHDLVLVHDFPYVDFVFSEQKMPSILQADRHRQCSIEFFTFSKSY
SMGGFRIGFAVGNADLITSLRKIKAIVDFNQYLGILNGAVTALKTSDAELQQTLSIFQKRRDVFVTALAKIGWVIPKPTA
TMYIWAPLPEPWQQQSVEFCKQLVLQTGVAASPGAGFGPAGEGYVRFALVQDPDTLNTAVDRIDSFLHT

Specific function: Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate, a reaction that requires three enzymes in E.coli

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. LL-diaminopimelate aminotransferase subfamily [H]

Homologues:

Organism=Homo sapiens, GI56713256, Length=421, Percent_Identity=20.6650831353919, Blast_Score=79, Evalue=8e-15,
Organism=Homo sapiens, GI56713254, Length=421, Percent_Identity=20.6650831353919, Blast_Score=79, Evalue=8e-15,
Organism=Escherichia coli, GI1788722, Length=387, Percent_Identity=37.7260981912145, Blast_Score=294, Evalue=7e-81,
Organism=Escherichia coli, GI1786816, Length=367, Percent_Identity=25.3405994550409, Blast_Score=115, Evalue=5e-27,
Organism=Escherichia coli, GI1788627, Length=242, Percent_Identity=27.2727272727273, Blast_Score=75, Evalue=7e-15,
Organism=Caenorhabditis elegans, GI71994472, Length=270, Percent_Identity=24.8148148148148, Blast_Score=91, Evalue=8e-19,
Organism=Caenorhabditis elegans, GI71994476, Length=270, Percent_Identity=24.8148148148148, Blast_Score=91, Evalue=8e-19,
Organism=Caenorhabditis elegans, GI17567369, Length=240, Percent_Identity=22.5, Blast_Score=72, Evalue=5e-13,
Organism=Saccharomyces cerevisiae, GI6322401, Length=390, Percent_Identity=20.5128205128205, Blast_Score=69, Evalue=1e-12,
Organism=Drosophila melanogaster, GI28573069, Length=388, Percent_Identity=22.1649484536082, Blast_Score=90, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24646114, Length=388, Percent_Identity=22.1649484536082, Blast_Score=90, Evalue=2e-18,
Organism=Drosophila melanogaster, GI28573067, Length=388, Percent_Identity=22.1649484536082, Blast_Score=90, Evalue=2e-18,
Organism=Drosophila melanogaster, GI28573065, Length=388, Percent_Identity=22.1649484536082, Blast_Score=90, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR019881
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.83 [H]

Molecular weight: Translated: 42954; Mature: 42954

Theoretical pI: Translated: 5.04; Mature: 5.04

Prosite motif: PS00599 AA_TRANSFER_CLASS_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFADRIQRFQANVFADMDQAKRQALDTGQSLIDLSLGSSDLPVAAPILETISQSLQDPS
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHHHHCCCC
THGYLLFHGTRSFREAVAAWYEQRFGLSVDPETEVLPLIGSQEGTAHLPLAILNPGDIAL
CCCEEEEECCHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCCCCCEEEECCCCEEE
LQDPGYPSHAGGVYLAGGEMYGMPLLAENQFLPVFSEIPTEVRQKARMMVLSYPHNPTTA
EECCCCCCCCCCEEEECCCEECCCEEECCCCCCHHHHCCHHHHHHHCEEEEECCCCCCHH
IAPLSFFQEAVQFCQDHDLVLVHDFPYVDFVFSEQKMPSILQADRHRQCSIEFFTFSKSY
HHHHHHHHHHHHHHCCCCEEEEECCCCEEEEECCCCCHHHHHHCCCCEEEEEEEEEECCC
SMGGFRIGFAVGNADLITSLRKIKAIVDFNQYLGILNGAVTALKTSDAELQQTLSIFQKR
CCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCHHHHHHHHHHHHHH
RDVFVTALAKIGWVIPKPTATMYIWAPLPEPWQQQSVEFCKQLVLQTGVAASPGAGFGPA
HHHHHHHHHHHCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
GEGYVRFALVQDPDTLNTAVDRIDSFLHT
CCCEEEEEEEECCCHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKFADRIQRFQANVFADMDQAKRQALDTGQSLIDLSLGSSDLPVAAPILETISQSLQDPS
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHHHHCCCC
THGYLLFHGTRSFREAVAAWYEQRFGLSVDPETEVLPLIGSQEGTAHLPLAILNPGDIAL
CCCEEEEECCHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCCCCCEEEECCCCEEE
LQDPGYPSHAGGVYLAGGEMYGMPLLAENQFLPVFSEIPTEVRQKARMMVLSYPHNPTTA
EECCCCCCCCCCEEEECCCEECCCEEECCCCCCHHHHCCHHHHHHHCEEEEECCCCCCHH
IAPLSFFQEAVQFCQDHDLVLVHDFPYVDFVFSEQKMPSILQADRHRQCSIEFFTFSKSY
HHHHHHHHHHHHHHCCCCEEEEECCCCEEEEECCCCCHHHHHHCCCCEEEEEEEEEECCC
SMGGFRIGFAVGNADLITSLRKIKAIVDFNQYLGILNGAVTALKTSDAELQQTLSIFQKR
CCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCHHHHHHHHHHHHHH
RDVFVTALAKIGWVIPKPTATMYIWAPLPEPWQQQSVEFCKQLVLQTGVAASPGAGFGPA
HHHHHHHHHHHCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
GEGYVRFALVQDPDTLNTAVDRIDSFLHT
CCCEEEEEEEECCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA