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The map label for this gene is torS [H]

Identifier: 158336699

GI number: 158336699

Start: 3615243

End: 3616517

Strand: Direct

Name: torS [H]

Synonym: AM1_3567

Alternate gene names: 158336699

Gene position: 3615243-3616517 (Clockwise)

Preceding gene: 158336698

Following gene: 158336700

Centisome position: 55.59

GC content: 46.35

Gene sequence:

>1275_bases
ATGCCTAAACCCATAATTGTTTGTGTGGATGATGAAATCGCAGTCCTAGATAGCCTCAGACGTGAGCTATCTGAAGTGTT
TGAAGATACCTGCGAAATAGAAACTGCTATGGGGGGCAAGGATGCCATTGCCCTGGTCCATGACCTGATCGAAGATGAAT
GCGATTTATCGGTCATCATTGCTGATTATCTGATGCCAGACATCAAAGGAGACGCAGTCTTACAACAAGTCCATCAGCTC
TCTCCCCAAACTTTGACCATTATGTTGACGGGGCAAGCGAATGTTGATGGTATTTCCAATGCCATCAATACGGCCCAGCT
GTATCACTACATTGCCAAACCCTGGCAACCTGAAGCGTTACAGTTAACGGTGCGAGAGGCTCTCAATCGCTATCAACTCT
CTAAAAAAATTAAAGACTATCAACAAACCCTCGAACGTAAAGTTGAAGAGCGTACCCAGGAATTATCCGAAACGTTGCAT
ACCCTGCAAACCACCCAATCAGAACTGATTCAGGCGGAAAAAATGGCTGCCCTAGGCCAGTTAGTGGCGGGCGTAGCCCA
TGAAATTAATACCCCTGTGGGCAATGCCCTGTTAGCCGCCTCGGTATTGAATAATGAAACCAGTTCTTTAACTCAAGCCT
TTGAGCAAGGAGCGTTAAAACGATCGGCCTTAGTGGGTTATTTGCAGACTGCTCAAGAGAGTAGTGATCTGATCTTGCAA
AATCTGCATGGGGCGGCGGCCCTCATTCAAAACTTCAAGCAAGTTGCGGTGGATCAAACCAGTCATGAGCAACGAGAGTT
TCAGATCATCCCGTATATTGAGAGTGTATTGACCAATTTGGAACCGAAATTAAAACGGACTCGCCATACGGTGACGGTTT
CAGGGGATGCTGCTCTAAAAACCACTAGTTATCCAGGAGCACTGTCACAAGTTGTGACTAATTTTGTCATGAATTCCCTT
ATGCATGCCTACCAACCTGGAGAGGCAGGGCAATTAAAATTTGAAGTGACTCAACAACAAGATCGGATTATTCTCGAATA
TACCGATGATGGTTGTGGCATTCCAGCAGAACATCAGCCTAAGATTTATGAACCTTTTTTTACCACGGGTCGAGATCGGG
GCGGCAGTGGTTTAGGTCTGCATATTGTTCACAATCTGGTCACCCAGTCCCTTGGAGGAACCTTGTCTTGCCAGAGTGAG
GTTTCCGTAGGAACTCAGTTTATGCTGCAGTTACCCTTGACCTTAAGGAAGGGGGAGGCTCATGCCCGAGGATAA

Upstream 100 bases:

>100_bases
AGCCAATCTGTTTAATTGTTTACGCAAACCCTGGAATGAAAGTGATCTGATCCAATGTATTCAATCAGCCTTAGGAACAG
TGTAAAGACTAATCAGGACG

Downstream 100 bases:

>100_bases
ATCCTTGCTTTCTGCAGGAACTCTAGAAGCCGATGATGAACTCCAGTTTTTGGAAGAGTTAGCCTGCCATTCCCAGAGGG
AGGTGATTCCAGGAGGATGG

Product: multi-sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 424; Mature: 423

Protein sequence:

>424_residues
MPKPIIVCVDDEIAVLDSLRRELSEVFEDTCEIETAMGGKDAIALVHDLIEDECDLSVIIADYLMPDIKGDAVLQQVHQL
SPQTLTIMLTGQANVDGISNAINTAQLYHYIAKPWQPEALQLTVREALNRYQLSKKIKDYQQTLERKVEERTQELSETLH
TLQTTQSELIQAEKMAALGQLVAGVAHEINTPVGNALLAASVLNNETSSLTQAFEQGALKRSALVGYLQTAQESSDLILQ
NLHGAAALIQNFKQVAVDQTSHEQREFQIIPYIESVLTNLEPKLKRTRHTVTVSGDAALKTTSYPGALSQVVTNFVMNSL
MHAYQPGEAGQLKFEVTQQQDRIILEYTDDGCGIPAEHQPKIYEPFFTTGRDRGGSGLGLHIVHNLVTQSLGGTLSCQSE
VSVGTQFMLQLPLTLRKGEAHARG

Sequences:

>Translated_424_residues
MPKPIIVCVDDEIAVLDSLRRELSEVFEDTCEIETAMGGKDAIALVHDLIEDECDLSVIIADYLMPDIKGDAVLQQVHQL
SPQTLTIMLTGQANVDGISNAINTAQLYHYIAKPWQPEALQLTVREALNRYQLSKKIKDYQQTLERKVEERTQELSETLH
TLQTTQSELIQAEKMAALGQLVAGVAHEINTPVGNALLAASVLNNETSSLTQAFEQGALKRSALVGYLQTAQESSDLILQ
NLHGAAALIQNFKQVAVDQTSHEQREFQIIPYIESVLTNLEPKLKRTRHTVTVSGDAALKTTSYPGALSQVVTNFVMNSL
MHAYQPGEAGQLKFEVTQQQDRIILEYTDDGCGIPAEHQPKIYEPFFTTGRDRGGSGLGLHIVHNLVTQSLGGTLSCQSE
VSVGTQFMLQLPLTLRKGEAHARG
>Mature_423_residues
PKPIIVCVDDEIAVLDSLRRELSEVFEDTCEIETAMGGKDAIALVHDLIEDECDLSVIIADYLMPDIKGDAVLQQVHQLS
PQTLTIMLTGQANVDGISNAINTAQLYHYIAKPWQPEALQLTVREALNRYQLSKKIKDYQQTLERKVEERTQELSETLHT
LQTTQSELIQAEKMAALGQLVAGVAHEINTPVGNALLAASVLNNETSSLTQAFEQGALKRSALVGYLQTAQESSDLILQN
LHGAAALIQNFKQVAVDQTSHEQREFQIIPYIESVLTNLEPKLKRTRHTVTVSGDAALKTTSYPGALSQVVTNFVMNSLM
HAYQPGEAGQLKFEVTQQQDRIILEYTDDGCGIPAEHQPKIYEPFFTTGRDRGGSGLGLHIVHNLVTQSLGGTLSCQSEV
SVGTQFMLQLPLTLRKGEAHARG

Specific function: Member of the two-component regulatory system torS/torR involved in the anaerobic utilization of trimethylamine-N-oxide (TMAO). Detects the presence of TMAO in the medium and, in response, activates torR via a four-step phosphorelay. When TMAO is removed,

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI87081816, Length=290, Percent_Identity=28.9655172413793, Blast_Score=88, Evalue=9e-19,
Organism=Escherichia coli, GI1790436, Length=265, Percent_Identity=28.3018867924528, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI145693157, Length=274, Percent_Identity=26.2773722627737, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI1789149, Length=300, Percent_Identity=23.6666666666667, Blast_Score=68, Evalue=9e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR008207
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR014302
- InterPro:   IPR001789 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF01627 Hpt; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 46624; Mature: 46492

Theoretical pI: Translated: 4.82; Mature: 4.82

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPKPIIVCVDDEIAVLDSLRRELSEVFEDTCEIETAMGGKDAIALVHDLIEDECDLSVII
CCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCEEHH
ADYLMPDIKGDAVLQQVHQLSPQTLTIMLTGQANVDGISNAINTAQLYHYIAKPWQPEAL
HHHHCCCCCHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCHHH
QLTVREALNRYQLSKKIKDYQQTLERKVEERTQELSETLHTLQTTQSELIQAEKMAALGQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LVAGVAHEINTPVGNALLAASVLNNETSSLTQAFEQGALKRSALVGYLQTAQESSDLILQ
HHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
NLHGAAALIQNFKQVAVDQTSHEQREFQIIPYIESVLTNLEPKLKRTRHTVTVSGDAALK
HHHHHHHHHHHHHHHHHCCCCCHHHHEEEHHHHHHHHHCCCHHHHHCCEEEEECCCCEEE
TTSYPGALSQVVTNFVMNSLMHAYQPGEAGQLKFEVTQQQDRIILEYTDDGCGIPAEHQP
ECCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCEEEEECCCCCCCCCCCCC
KIYEPFFTTGRDRGGSGLGLHIVHNLVTQSLGGTLSCQSEVSVGTQFMLQLPLTLRKGEA
CCCCCHHHCCCCCCCCCCHHHHHHHHHHHHCCCCEECCHHHHHHHHHHHHCCCCEECCCC
HARG
CCCC
>Mature Secondary Structure 
PKPIIVCVDDEIAVLDSLRRELSEVFEDTCEIETAMGGKDAIALVHDLIEDECDLSVII
CCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCEEHH
ADYLMPDIKGDAVLQQVHQLSPQTLTIMLTGQANVDGISNAINTAQLYHYIAKPWQPEAL
HHHHCCCCCHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCHHH
QLTVREALNRYQLSKKIKDYQQTLERKVEERTQELSETLHTLQTTQSELIQAEKMAALGQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LVAGVAHEINTPVGNALLAASVLNNETSSLTQAFEQGALKRSALVGYLQTAQESSDLILQ
HHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
NLHGAAALIQNFKQVAVDQTSHEQREFQIIPYIESVLTNLEPKLKRTRHTVTVSGDAALK
HHHHHHHHHHHHHHHHHCCCCCHHHHEEEHHHHHHHHHCCCHHHHHCCEEEEECCCCEEE
TTSYPGALSQVVTNFVMNSLMHAYQPGEAGQLKFEVTQQQDRIILEYTDDGCGIPAEHQP
ECCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCEEEEECCCCCCCCCCCCC
KIYEPFFTTGRDRGGSGLGLHIVHNLVTQSLGGTLSCQSEVSVGTQFMLQLPLTLRKGEA
CCCCCHHHCCCCCCCCCCHHHHHHHHHHHHCCCCEECCHHHHHHHHHHHHCCCCEECCCC
HARG
CCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]