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The map label for this gene is cph2 [H]

Identifier: 158336700

GI number: 158336700

Start: 3616504

End: 3617766

Strand: Direct

Name: cph2 [H]

Synonym: AM1_3568

Alternate gene names: 158336700

Gene position: 3616504-3617766 (Clockwise)

Preceding gene: 158336699

Following gene: 158336701

Centisome position: 55.61

GC content: 46.63

Gene sequence:

>1263_bases
ATGCCCGAGGATAAATCCTTGCTTTCTGCAGGAACTCTAGAAGCCGATGATGAACTCCAGTTTTTGGAAGAGTTAGCCTG
CCATTCCCAGAGGGAGGTGATTCCAGGAGGATGGAAAGTCATTGTAGTGGACGATGAAGAACAGGTTCATGAGGTGACGC
GTCTCGCCCTGAAAAACTTCAAATTTGCTGATAAGCCCCTGGAAATTATTTCGGCTTATTCCAGTGAAGAAGCTCAGCAG
TTATTGAATCAAAACCCAGATACAGCGGTGTTGCTGTTAGATGTGGTGATGGAGACGGATGAAGCTGGCCTAGAGCTGGT
CAAGCATATCCGTGATCATTTACACAACATCTTTGTGCGGATTATTTTACGCACTGGTCAGCCGGGTATCGCTCCCGAAA
AATCGGTGATTGAAGGGTATGACATTAATGACTACAAAACTAAAACCGAACTCACCCAACAAAAACTTTTTTCCACGTTA
ATTACGGCTATTCGATCGTATCGAGATTTACTGACTGTTGAAGAGAGCCGTCAACAGATTGCGTATTTAAATCAACAGTT
AGAAGATGCCAAACTCAGTTTGGAGAATAAGGTTAAAGAACGCACCCAAGCGCTGCAGCAGCAAACCTTAGCCTTAGCAG
CTAAAAACAAGCAGCTAGAAGAAGAGATTCAGGCCAAGCTCTATGCCCAGCAGGCTTTAGAAGCGACCAATAAGAAGTTG
GATGAAGCCAATAAGCAGCTGTCTCTGATTGCGAATCATGATGCCCTCACGGGGTTGGCGAACCGCCGTCGTTTTGATGA
GTATTTACAACAAATTTGGAAGCAAACTCAGCGGGAACAACAGCCCTTAAGCCTTTTAATTTGCGATATTGATTTTTTCA
AGCAGTATAACGATACCTATGGTCACCTAGAGGGAGATATTTGCCTCCGAACGGTGGCCCAAAAGATTCACCAAACCATT
GTGCGTCCTTTGGATTTAGTGGCCCGCTTTGGAGGGGAAGAATTTGCGATTGTGTTGCCCAATACCGATTTAGAGGGAGG
GCAAGTGGTGGCGGAGCGCCTGAGAATGATCATCCAGAAGTCTCAACTTCCCCATCGTGGATCTTCTGTGAGCGAATTTG
TGACCGTTAGCATTGGGGCCGCTACGGTGCGATCACATCCCCATACCTCCGTATCGAGCTTAATCAGCCGAGCCGATCAG
GCCCTCTATCAAGCGAAACAATCTGGACGAGACCAGGTGGTTGCTCTATCGATAACGGAGTAG

Upstream 100 bases:

>100_bases
ACCCAGTCCCTTGGAGGAACCTTGTCTTGCCAGAGTGAGGTTTCCGTAGGAACTCAGTTTATGCTGCAGTTACCCTTGAC
CTTAAGGAAGGGGGAGGCTC

Downstream 100 bases:

>100_bases
GTTTTTCAGCAGGAGAAGAGTGCGATTTACAGACAGCCGGGGAACACTGGATGTAATTCGCGAGATCAGCCGAACGGCCA
TGCAAGACGTCAATGCTCCA

Product: diguanylate cyclase

Products: NA

Alternate protein names: Bacteriophytochrome cph2 [H]

Number of amino acids: Translated: 420; Mature: 419

Protein sequence:

>420_residues
MPEDKSLLSAGTLEADDELQFLEELACHSQREVIPGGWKVIVVDDEEQVHEVTRLALKNFKFADKPLEIISAYSSEEAQQ
LLNQNPDTAVLLLDVVMETDEAGLELVKHIRDHLHNIFVRIILRTGQPGIAPEKSVIEGYDINDYKTKTELTQQKLFSTL
ITAIRSYRDLLTVEESRQQIAYLNQQLEDAKLSLENKVKERTQALQQQTLALAAKNKQLEEEIQAKLYAQQALEATNKKL
DEANKQLSLIANHDALTGLANRRRFDEYLQQIWKQTQREQQPLSLLICDIDFFKQYNDTYGHLEGDICLRTVAQKIHQTI
VRPLDLVARFGGEEFAIVLPNTDLEGGQVVAERLRMIIQKSQLPHRGSSVSEFVTVSIGAATVRSHPHTSVSSLISRADQ
ALYQAKQSGRDQVVALSITE

Sequences:

>Translated_420_residues
MPEDKSLLSAGTLEADDELQFLEELACHSQREVIPGGWKVIVVDDEEQVHEVTRLALKNFKFADKPLEIISAYSSEEAQQ
LLNQNPDTAVLLLDVVMETDEAGLELVKHIRDHLHNIFVRIILRTGQPGIAPEKSVIEGYDINDYKTKTELTQQKLFSTL
ITAIRSYRDLLTVEESRQQIAYLNQQLEDAKLSLENKVKERTQALQQQTLALAAKNKQLEEEIQAKLYAQQALEATNKKL
DEANKQLSLIANHDALTGLANRRRFDEYLQQIWKQTQREQQPLSLLICDIDFFKQYNDTYGHLEGDICLRTVAQKIHQTI
VRPLDLVARFGGEEFAIVLPNTDLEGGQVVAERLRMIIQKSQLPHRGSSVSEFVTVSIGAATVRSHPHTSVSSLISRADQ
ALYQAKQSGRDQVVALSITE
>Mature_419_residues
PEDKSLLSAGTLEADDELQFLEELACHSQREVIPGGWKVIVVDDEEQVHEVTRLALKNFKFADKPLEIISAYSSEEAQQL
LNQNPDTAVLLLDVVMETDEAGLELVKHIRDHLHNIFVRIILRTGQPGIAPEKSVIEGYDINDYKTKTELTQQKLFSTLI
TAIRSYRDLLTVEESRQQIAYLNQQLEDAKLSLENKVKERTQALQQQTLALAAKNKQLEEEIQAKLYAQQALEATNKKLD
EANKQLSLIANHDALTGLANRRRFDEYLQQIWKQTQREQQPLSLLICDIDFFKQYNDTYGHLEGDICLRTVAQKIHQTIV
RPLDLVARFGGEEFAIVLPNTDLEGGQVVAERLRMIIQKSQLPHRGSSVSEFVTVSIGAATVRSHPHTSVSSLISRADQA
LYQAKQSGRDQVVALSITE

Specific function: Photoreceptor which exists in two forms that are reversibly interconvertible by light:the R form that absorbs maximally in the red region of the spectrum and the FR form that absorbs maximally in the far-red region [H]

COG id: COG2199

COG function: function code T; FOG: GGDEF domain

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 GGDEF domains [H]

Homologues:

Organism=Escherichia coli, GI87081881, Length=178, Percent_Identity=41.0112359550562, Blast_Score=112, Evalue=7e-26,
Organism=Escherichia coli, GI145693134, Length=161, Percent_Identity=40.9937888198758, Blast_Score=107, Evalue=2e-24,
Organism=Escherichia coli, GI1787262, Length=166, Percent_Identity=37.3493975903614, Blast_Score=106, Evalue=2e-24,
Organism=Escherichia coli, GI1787816, Length=170, Percent_Identity=35.2941176470588, Blast_Score=101, Evalue=8e-23,
Organism=Escherichia coli, GI1786584, Length=178, Percent_Identity=32.0224719101124, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1788381, Length=169, Percent_Identity=33.7278106508876, Blast_Score=96, Evalue=5e-21,
Organism=Escherichia coli, GI87082007, Length=166, Percent_Identity=36.144578313253, Blast_Score=95, Evalue=8e-21,
Organism=Escherichia coli, GI1787802, Length=176, Percent_Identity=34.6590909090909, Blast_Score=93, Evalue=4e-20,
Organism=Escherichia coli, GI1787541, Length=175, Percent_Identity=31.4285714285714, Blast_Score=88, Evalue=8e-19,
Organism=Escherichia coli, GI1788085, Length=166, Percent_Identity=31.9277108433735, Blast_Score=76, Evalue=4e-15,
Organism=Escherichia coli, GI1788956, Length=179, Percent_Identity=33.5195530726257, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI87081977, Length=174, Percent_Identity=31.0344827586207, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1787056, Length=162, Percent_Identity=33.9506172839506, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI87081974, Length=101, Percent_Identity=36.6336633663366, Blast_Score=65, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR003018
- InterPro:   IPR016132
- InterPro:   IPR001294
- InterPro:   IPR013515 [H]

Pfam domain/function: PF00563 EAL; PF01590 GAF; PF00990 GGDEF; PF00360 Phytochrome [H]

EC number: NA

Molecular weight: Translated: 47458; Mature: 47327

Theoretical pI: Translated: 5.05; Mature: 5.05

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPEDKSLLSAGTLEADDELQFLEELACHSQREVIPGGWKVIVVDDEEQVHEVTRLALKNF
CCCCHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCCCCCEEEEECCHHHHHHHHHHHHHHC
KFADKPLEIISAYSSEEAQQLLNQNPDTAVLLLDVVMETDEAGLELVKHIRDHLHNIFVR
CCCCCHHHHHHHHCHHHHHHHHHCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
IILRTGQPGIAPEKSVIEGYDINDYKTKTELTQQKLFSTLITAIRSYRDLLTVEESRQQI
HHHHCCCCCCCCCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AYLNQQLEDAKLSLENKVKERTQALQQQTLALAAKNKQLEEEIQAKLYAQQALEATNKKL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DEANKQLSLIANHDALTGLANRRRFDEYLQQIWKQTQREQQPLSLLICDIDFFKQYNDTY
HHHHHHEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECHHHHHHHCCCC
GHLEGDICLRTVAQKIHQTIVRPLDLVARFGGEEFAIVLPNTDLEGGQVVAERLRMIIQK
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHHHHHHH
SQLPHRGSSVSEFVTVSIGAATVRSHPHTSVSSLISRADQALYQAKQSGRDQVVALSITE
HCCCCCCCCHHHHHEEEECHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECC
>Mature Secondary Structure 
PEDKSLLSAGTLEADDELQFLEELACHSQREVIPGGWKVIVVDDEEQVHEVTRLALKNF
CCCHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCCCCCEEEEECCHHHHHHHHHHHHHHC
KFADKPLEIISAYSSEEAQQLLNQNPDTAVLLLDVVMETDEAGLELVKHIRDHLHNIFVR
CCCCCHHHHHHHHCHHHHHHHHHCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
IILRTGQPGIAPEKSVIEGYDINDYKTKTELTQQKLFSTLITAIRSYRDLLTVEESRQQI
HHHHCCCCCCCCCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AYLNQQLEDAKLSLENKVKERTQALQQQTLALAAKNKQLEEEIQAKLYAQQALEATNKKL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DEANKQLSLIANHDALTGLANRRRFDEYLQQIWKQTQREQQPLSLLICDIDFFKQYNDTY
HHHHHHEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECHHHHHHHCCCC
GHLEGDICLRTVAQKIHQTIVRPLDLVARFGGEEFAIVLPNTDLEGGQVVAERLRMIIQK
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHHHHHHH
SQLPHRGSSVSEFVTVSIGAATVRSHPHTSVSSLISRADQALYQAKQSGRDQVVALSITE
HCCCCCCCCHHHHHEEEECHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231; 10978170; 11063585 [H]