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The map label for this gene is cph2 [H]

Identifier: 158336630

GI number: 158336630

Start: 3536794

End: 3538095

Strand: Direct

Name: cph2 [H]

Synonym: AM1_3498

Alternate gene names: 158336630

Gene position: 3536794-3538095 (Clockwise)

Preceding gene: 158336627

Following gene: 158336631

Centisome position: 54.38

GC content: 48.0

Gene sequence:

>1302_bases
ATGTTAGGTACATTCCTAAATCGGCTGCTTCAGCGTTTGTACCAGCGGGTGATTATGATTATGATCATCTTGTTCAGTCT
AGGGCTAGGAGTCGCTTTTGTAGGTACCTACTATCTCTCCATATATTGGGTAGATAGCCAAGCGGTGCAATATTCAAGCG
TTGTTATTCAGACCTTAAATCAGGCCCGGCGGTTCTATAGCGAAGATGTTGTTGATCGCCTAGAGTCTATCAAGGGTGTG
CAAGTTATCCCTGAATATCATGCTGTCAGTGGCGGCATTCCCAACCCCGCCACCTTTACGATTGAATTGGGTGAATTGCT
GAGTAATCAGTCCACAGGGACCATCTTCCGACTCTATAGCAACTTTCCGTTTCCCCATCGACAGGCCACAGGAGGCCCTC
AAGATCAATTTGAACGGGCTGCACTCAACTATCTCCAAAATCATCCCCAGGCCGCTTACTATCGCAAAGAGCGAGTGGGA
GATCGTCTTTCATTTCGATATACAGAAGCTGTTTTGATGGAACCCAGTTGTGTCGCATGCCACAATACATTGCCCAGTAG
CCCCAAAAAAGACTGGAAGGTTGGTCAGGTTCGAGGGATTGCCGAAATCACACAGCCTCTCGAACAGGGCCTACAAACGG
CTCAGGGAGGTTTAAAGACTATCTATCTGGCCCTGACCATCATCATCACGTTGGCCATGATGGGGTTGGGGCTGGCTGTG
GGTCGGTTCCGCACCCTTAATCAGGAACTAGAGAAGAAAGTTGCGGAAAGAACAGCTGCCCTTGAGCGATTAGCCATGGT
GGATGAGCTGACTCAATTGGCCAACCGACGCCAATTTGATCAGCGTTTAGAGCAGGCCTGGAAAGTCGCTCGGAGACAGC
AGCACCCTTTATCTTTAATTTTGTGTGATGTTGATTATTTCAAAAACTACAACGATACCTATGGTCATCCAGCCGGAGAT
GAATGCTTGCGGTCGATAGCCAAAGTCTTAGACAGGAGCATCAGACGTCCTGGAGAATTTTCTGCCCGGTATGGTGGTGA
AGAGTTTGCCATAGTTTTACCCAATGTCAGTCGTATGGATGCCATCCAAATCGTCACGACGATTCAAACGGCCATTCACC
AACTCCAAATTCCTCATCGCTCATCTTTAAACCATGCTTCTGTCACGCTAAGCCTGGGCATTGCCACGATGATTCCCAAT
GCTAATTATTCCCCTGAACAATTGATACAAGCAGCGGATGAAGCCCTATACCAAGCTAAGCATCAAGGGCGAGATCGATA
TGTTGTCTGGGATAACCCGTAA

Upstream 100 bases:

>100_bases
AAGCCTAGACCATTGGAGAATTGTAATTTTTAGCTAGAATCATCATCCTTGATATAAGAGTGGGCAACCTGATTTATCCC
AACTCCACCCTGGTTTGATG

Downstream 100 bases:

>100_bases
GGAGCATTACCGTAGATAAAATTTATGATGCCGCTGATGGGTGAATTGGTTGAGTGTCTTGCTCAGAGTGTCGGACTCAA
ACCCTGAACTCTACAATATT

Product: diguanylate cyclase

Products: NA

Alternate protein names: Bacteriophytochrome cph2 [H]

Number of amino acids: Translated: 433; Mature: 433

Protein sequence:

>433_residues
MLGTFLNRLLQRLYQRVIMIMIILFSLGLGVAFVGTYYLSIYWVDSQAVQYSSVVIQTLNQARRFYSEDVVDRLESIKGV
QVIPEYHAVSGGIPNPATFTIELGELLSNQSTGTIFRLYSNFPFPHRQATGGPQDQFERAALNYLQNHPQAAYYRKERVG
DRLSFRYTEAVLMEPSCVACHNTLPSSPKKDWKVGQVRGIAEITQPLEQGLQTAQGGLKTIYLALTIIITLAMMGLGLAV
GRFRTLNQELEKKVAERTAALERLAMVDELTQLANRRQFDQRLEQAWKVARRQQHPLSLILCDVDYFKNYNDTYGHPAGD
ECLRSIAKVLDRSIRRPGEFSARYGGEEFAIVLPNVSRMDAIQIVTTIQTAIHQLQIPHRSSLNHASVTLSLGIATMIPN
ANYSPEQLIQAADEALYQAKHQGRDRYVVWDNP

Sequences:

>Translated_433_residues
MLGTFLNRLLQRLYQRVIMIMIILFSLGLGVAFVGTYYLSIYWVDSQAVQYSSVVIQTLNQARRFYSEDVVDRLESIKGV
QVIPEYHAVSGGIPNPATFTIELGELLSNQSTGTIFRLYSNFPFPHRQATGGPQDQFERAALNYLQNHPQAAYYRKERVG
DRLSFRYTEAVLMEPSCVACHNTLPSSPKKDWKVGQVRGIAEITQPLEQGLQTAQGGLKTIYLALTIIITLAMMGLGLAV
GRFRTLNQELEKKVAERTAALERLAMVDELTQLANRRQFDQRLEQAWKVARRQQHPLSLILCDVDYFKNYNDTYGHPAGD
ECLRSIAKVLDRSIRRPGEFSARYGGEEFAIVLPNVSRMDAIQIVTTIQTAIHQLQIPHRSSLNHASVTLSLGIATMIPN
ANYSPEQLIQAADEALYQAKHQGRDRYVVWDNP
>Mature_433_residues
MLGTFLNRLLQRLYQRVIMIMIILFSLGLGVAFVGTYYLSIYWVDSQAVQYSSVVIQTLNQARRFYSEDVVDRLESIKGV
QVIPEYHAVSGGIPNPATFTIELGELLSNQSTGTIFRLYSNFPFPHRQATGGPQDQFERAALNYLQNHPQAAYYRKERVG
DRLSFRYTEAVLMEPSCVACHNTLPSSPKKDWKVGQVRGIAEITQPLEQGLQTAQGGLKTIYLALTIIITLAMMGLGLAV
GRFRTLNQELEKKVAERTAALERLAMVDELTQLANRRQFDQRLEQAWKVARRQQHPLSLILCDVDYFKNYNDTYGHPAGD
ECLRSIAKVLDRSIRRPGEFSARYGGEEFAIVLPNVSRMDAIQIVTTIQTAIHQLQIPHRSSLNHASVTLSLGIATMIPN
ANYSPEQLIQAADEALYQAKHQGRDRYVVWDNP

Specific function: Photoreceptor which exists in two forms that are reversibly interconvertible by light:the R form that absorbs maximally in the red region of the spectrum and the FR form that absorbs maximally in the far-red region [H]

COG id: COG3706

COG function: function code T; Response regulator containing a CheY-like receiver domain and a GGDEF domain

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 GGDEF domains [H]

Homologues:

Organism=Escherichia coli, GI145693134, Length=191, Percent_Identity=35.0785340314136, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI1786584, Length=205, Percent_Identity=28.2926829268293, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI87082007, Length=242, Percent_Identity=29.7520661157025, Blast_Score=102, Evalue=4e-23,
Organism=Escherichia coli, GI1787262, Length=170, Percent_Identity=33.5294117647059, Blast_Score=102, Evalue=6e-23,
Organism=Escherichia coli, GI87081881, Length=168, Percent_Identity=39.2857142857143, Blast_Score=99, Evalue=5e-22,
Organism=Escherichia coli, GI1788381, Length=221, Percent_Identity=30.316742081448, Blast_Score=89, Evalue=6e-19,
Organism=Escherichia coli, GI1788956, Length=195, Percent_Identity=34.3589743589744, Blast_Score=87, Evalue=3e-18,
Organism=Escherichia coli, GI1787802, Length=184, Percent_Identity=32.0652173913043, Blast_Score=83, Evalue=3e-17,
Organism=Escherichia coli, GI1787816, Length=167, Percent_Identity=34.7305389221557, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI1787056, Length=160, Percent_Identity=33.125, Blast_Score=78, Evalue=9e-16,
Organism=Escherichia coli, GI1787541, Length=180, Percent_Identity=30.5555555555556, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI87081977, Length=187, Percent_Identity=31.0160427807487, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI1788085, Length=170, Percent_Identity=27.0588235294118, Blast_Score=64, Evalue=3e-11,
Organism=Escherichia coli, GI87081974, Length=166, Percent_Identity=28.3132530120482, Blast_Score=62, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR003018
- InterPro:   IPR016132
- InterPro:   IPR001294
- InterPro:   IPR013515 [H]

Pfam domain/function: PF00563 EAL; PF01590 GAF; PF00990 GGDEF; PF00360 Phytochrome [H]

EC number: NA

Molecular weight: Translated: 48924; Mature: 48924

Theoretical pI: Translated: 8.74; Mature: 8.74

Prosite motif: PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLGTFLNRLLQRLYQRVIMIMIILFSLGLGVAFVGTYYLSIYWVDSQAVQYSSVVIQTLN
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCHHHHHHHHHHHHHH
QARRFYSEDVVDRLESIKGVQVIPEYHAVSGGIPNPATFTIELGELLSNQSTGTIFRLYS
HHHHHHHHHHHHHHHHCCCCEECCCHHHHCCCCCCCCEEEEEHHHHHCCCCCCCEEEEEC
NFPFPHRQATGGPQDQFERAALNYLQNHPQAAYYRKERVGDRLSFRYTEAVLMEPSCVAC
CCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHHHCCCCHHHH
HNTLPSSPKKDWKVGQVRGIAEITQPLEQGLQTAQGGLKTIYLALTIIITLAMMGLGLAV
HCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHH
GRFRTLNQELEKKVAERTAALERLAMVDELTQLANRRQFDQRLEQAWKVARRQQHPLSLI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEE
LCDVDYFKNYNDTYGHPAGDECLRSIAKVLDRSIRRPGEFSARYGGEEFAIVLPNVSRMD
EECHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHCCCCEEEEECCCCCHHH
AIQIVTTIQTAIHQLQIPHRSSLNHASVTLSLGIATMIPNANYSPEQLIQAADEALYQAK
HHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEHHHHHCCCCCCCHHHHHHHHHHHHHHHH
HQGRDRYVVWDNP
HCCCCCEEEECCC
>Mature Secondary Structure
MLGTFLNRLLQRLYQRVIMIMIILFSLGLGVAFVGTYYLSIYWVDSQAVQYSSVVIQTLN
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCHHHHHHHHHHHHHH
QARRFYSEDVVDRLESIKGVQVIPEYHAVSGGIPNPATFTIELGELLSNQSTGTIFRLYS
HHHHHHHHHHHHHHHHCCCCEECCCHHHHCCCCCCCCEEEEEHHHHHCCCCCCCEEEEEC
NFPFPHRQATGGPQDQFERAALNYLQNHPQAAYYRKERVGDRLSFRYTEAVLMEPSCVAC
CCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHHHCCCCHHHH
HNTLPSSPKKDWKVGQVRGIAEITQPLEQGLQTAQGGLKTIYLALTIIITLAMMGLGLAV
HCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHH
GRFRTLNQELEKKVAERTAALERLAMVDELTQLANRRQFDQRLEQAWKVARRQQHPLSLI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEE
LCDVDYFKNYNDTYGHPAGDECLRSIAKVLDRSIRRPGEFSARYGGEEFAIVLPNVSRMD
EECHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHCCCCEEEEECCCCCHHH
AIQIVTTIQTAIHQLQIPHRSSLNHASVTLSLGIATMIPNANYSPEQLIQAADEALYQAK
HHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEHHHHHCCCCCCCHHHHHHHHHHHHHHHH
HQGRDRYVVWDNP
HCCCCCEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231; 10978170; 11063585 [H]