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The map label for this gene is btuR [C]

Identifier: 158335998

GI number: 158335998

Start: 2897817

End: 2898146

Strand: Direct

Name: btuR [C]

Synonym: AM1_2856

Alternate gene names: 158335998

Gene position: 2897817-2898146 (Clockwise)

Preceding gene: 158335995

Following gene: 158335999

Centisome position: 44.56

GC content: 47.58

Gene sequence:

>330_bases
ATGCATCTCTGTCAAAATTTGGACTGGTATCGCTGCAATTTACCGCGCTGTATTGATACACCAGAGTTAGAGGCCGATGA
AATGCAGGCCATGGAAGATCTTTGGCAGCATACAAAAACTGCGATCGCAGATGGGGATTACTCCCTTGTGATTTTGGATG
AACTCAGTTTGGCCCTCCACCTCAATCTCATTCCCGAATCAGAAGTCTTAGGGTTGATTAAGCAACGTCCTCAGCATATT
GATATGATTTTGACGGGGCCGAATATGCCCTCGTCCCTGATGGATGTCGCCGACCAAATTACTGAGATGCGACGCAGCGT
TTGCCCTTAG

Upstream 100 bases:

>100_bases
TTCGGTGATGGCGCAAGCACTTCGGGAGGCTGGGCAAGGGACGCGGGTACTCGTCGTCCAATTTTTGAAAGGGGGCATCA
ATATGGGCCACCACCACCCC

Downstream 100 bases:

>100_bases
TCCTGAAGAGGTTTCTGTGATCAAAAATGATGCCTGGATCACCAGGATGGCTAGTCAAGGCATGATTAGCCCTTTTGAAC
CCCAGCTCGTACGGGAAGTG

Product: cob(I)yrinic acid a,c-diamide adenosyltransferase

Products: triphosphate; adenosylcob(III)yrinic acid a,c-diamide; Adenosyl cobinamide

Alternate protein names: NA

Number of amino acids: Translated: 109; Mature: 109

Protein sequence:

>109_residues
MHLCQNLDWYRCNLPRCIDTPELEADEMQAMEDLWQHTKTAIADGDYSLVILDELSLALHLNLIPESEVLGLIKQRPQHI
DMILTGPNMPSSLMDVADQITEMRRSVCP

Sequences:

>Translated_109_residues
MHLCQNLDWYRCNLPRCIDTPELEADEMQAMEDLWQHTKTAIADGDYSLVILDELSLALHLNLIPESEVLGLIKQRPQHI
DMILTGPNMPSSLMDVADQITEMRRSVCP
>Mature_109_residues
MHLCQNLDWYRCNLPRCIDTPELEADEMQAMEDLWQHTKTAIADGDYSLVILDELSLALHLNLIPESEVLGLIKQRPQHI
DMILTGPNMPSSLMDVADQITEMRRSVCP

Specific function: Required For Both De Novo Synthesis Of The Corrin Ring For The Assimilation Of Exogenous Corrinoids. Participates In The Adenosylation Of A Variety Of Incomplete And Complete Corrinoids (By Similarity). [C]

COG id: COG2109

COG function: function code H; ATP:corrinoid adenosyltransferase

Gene ontology:
GO:0005524: Cob(I)yrinic acid a,c-diamide adenosyltransferase
GO:0008817: Cob(I)yrinic acid a,c-diamide adenosyltransferase
GO:0009236: Cob(I)yrinic acid a,c-diamide adenosyltransferase
GO:0016740: Cob(I)yrinic acid a,c-diamide adenosyltransferase

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003724 [H]

Pfam domain/function: PF02572 CobA_CobO_BtuR [H]

EC number: 2.5.1.17

Molecular weight: Translated: 12461; Mature: 12461

Theoretical pI: Translated: 4.21; Mature: 4.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.7 %Cys     (Translated Protein)
6.4 %Met     (Translated Protein)
10.1 %Cys+Met (Translated Protein)
3.7 %Cys     (Mature Protein)
6.4 %Met     (Mature Protein)
10.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHLCQNLDWYRCNLPRCIDTPELEADEMQAMEDLWQHTKTAIADGDYSLVILDELSLALH
CCCCCCCCEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCEEEE
LNLIPESEVLGLIKQRPQHIDMILTGPNMPSSLMDVADQITEMRRSVCP
EECCCCHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MHLCQNLDWYRCNLPRCIDTPELEADEMQAMEDLWQHTKTAIADGDYSLVILDELSLALH
CCCCCCCCEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCEEEE
LNLIPESEVLGLIKQRPQHIDMILTGPNMPSSLMDVADQITEMRRSVCP
EECCCCHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; cob(I)yrinic acid a,c-diamide; cobinamide

Specific reaction: (1) ATP + cob(I)yrinic acid a,c-diamide = triphosphate + adenosylcob(III)yrinic acid a,c-diamide; (2) ATP + cobinamide = triphosphate + adenosylcobinamide

General reaction: Adenosyl group transfer [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11759840; 7883709 [H]