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The map label for this gene is hypA [H]

Identifier: 158335976

GI number: 158335976

Start: 2877319

End: 2877699

Strand: Direct

Name: hypA [H]

Synonym: AM1_2834

Alternate gene names: 158335976

Gene position: 2877319-2877699 (Clockwise)

Preceding gene: 158335975

Following gene: 158335977

Centisome position: 44.24

GC content: 49.34

Gene sequence:

>381_bases
ATGCATGAAACGGATATGACCAAGGCCCTAATTATGACGGTCAAGGACTGGTACGATTCCCAGCCTGAAGATCCACAAAT
CACCAAAATTCATTTGGTGGTGGGTCGGTTTACCTGTGTGGAACCTGTCAGTTTGCAGTTCGCTTATGAAGTCCAGACTC
GGGACACCTTCTTAGCGGGGACAGAGTTGGTGATTCGGGAGACCCCTTTAATCGCTTTTTGCCACCCCTGTCAGCAGGAA
TATTCTCCTGAAATGGGCTTGCAATATGCCTGTCCCACGTGTGGAGCCCCCATGGAAGATATCCGGTCCGGCCGCGAACT
CAAAATTGACCACATCGAATATTGTTCTGATTCAGCCCAAACCTATGCACCAAACTGTTGA

Upstream 100 bases:

>100_bases
GGCCCATCTTGTGCTGTCGGGGCAACTTCCCCGGCAAAAAGCACCAGACTATATTCATCCTGAAGCCAATATGGCAGTAG
GTTCTGAGTGGGTTTAGGCC

Downstream 100 bases:

>100_bases
CGCCGCCCTCGGCATTAACCTCTTACATGCCAATCAAGAAGGGGCCGATCACAACCAGGCTCACTTTAACGAATGGGGAG
TGACCTGCTTTAACGTCATG

Product: hydrogenase nickel insertion protein HypA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 126; Mature: 126

Protein sequence:

>126_residues
MHETDMTKALIMTVKDWYDSQPEDPQITKIHLVVGRFTCVEPVSLQFAYEVQTRDTFLAGTELVIRETPLIAFCHPCQQE
YSPEMGLQYACPTCGAPMEDIRSGRELKIDHIEYCSDSAQTYAPNC

Sequences:

>Translated_126_residues
MHETDMTKALIMTVKDWYDSQPEDPQITKIHLVVGRFTCVEPVSLQFAYEVQTRDTFLAGTELVIRETPLIAFCHPCQQE
YSPEMGLQYACPTCGAPMEDIRSGRELKIDHIEYCSDSAQTYAPNC
>Mature_126_residues
MHETDMTKALIMTVKDWYDSQPEDPQITKIHLVVGRFTCVEPVSLQFAYEVQTRDTFLAGTELVIRETPLIAFCHPCQQE
YSPEMGLQYACPTCGAPMEDIRSGRELKIDHIEYCSDSAQTYAPNC

Specific function: Probably plays a role in an hydrogenase nickel cofactor insertion step [H]

COG id: COG0375

COG function: function code R; Zn finger protein HypA/HybF (possibly regulating hydrogenase expression)

Gene ontology:
GO:0006464: Probable hydrogenase nickel incorporation protein hypA 1
GO:0016151: Probable hydrogenase nickel incorporation protein hypA 1
GO:0046872: Probable hydrogenase nickel incorporation protein hypA 1

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hypA/hybF family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000688
- InterPro:   IPR020538 [H]

Pfam domain/function: PF01155 HypA [H]

EC number: NA

Molecular weight: Translated: 14339; Mature: 14339

Theoretical pI: Translated: 4.37; Mature: 4.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

5.6 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
9.5 %Cys+Met (Translated Protein)
5.6 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
9.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHETDMTKALIMTVKDWYDSQPEDPQITKIHLVVGRFTCVEPVSLQFAYEVQTRDTFLAG
CCCCHHHHHHHHHHHHHCCCCCCCCCEEEEEEEEECEEECCCCEEEEEEEECCCCEEECC
TELVIRETPLIAFCHPCQQEYSPEMGLQYACPTCGAPMEDIRSGRELKIDHIEYCSDSAQ
CEEEEECCCEEEEECCHHHHCCCCCCCEEECCCCCCCHHHHCCCCEEEEHHHHHCCCCCC
TYAPNC
CCCCCC
>Mature Secondary Structure
MHETDMTKALIMTVKDWYDSQPEDPQITKIHLVVGRFTCVEPVSLQFAYEVQTRDTFLAG
CCCCHHHHHHHHHHHHHCCCCCCCCCEEEEEEEEECEEECCCCEEEEEEEECCCCEEECC
TELVIRETPLIAFCHPCQQEYSPEMGLQYACPTCGAPMEDIRSGRELKIDHIEYCSDSAQ
CEEEEECCCEEEEECCHHHHCCCCCCCEEECCCCCCCHHHHCCCCEEEEHHHHHCCCCCC
TYAPNC
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]