Click here to switch to the map view.

The map label for this gene is hypB [H]

Identifier: 158335977

GI number: 158335977

Start: 2877683

End: 2878381

Strand: Direct

Name: hypB [H]

Synonym: AM1_2835

Alternate gene names: 158335977

Gene position: 2877683-2878381 (Clockwise)

Preceding gene: 158335976

Following gene: 158335978

Centisome position: 44.25

GC content: 50.21

Gene sequence:

>699_bases
ATGCACCAAACTGTTGACGCCGCCCTCGGCATTAACCTCTTACATGCCAATCAAGAAGGGGCCGATCACAACCAGGCTCA
CTTTAACGAATGGGGAGTGACCTGCTTTAACGTCATGAGCAGTCCAGGTGCAGGGAAAACGGTTCTGTTAGAGAAAACTC
TGGCAGCTCTCAGCCCAGACCTCAATCTGGCCGTCATTGAAGGGGACATGACTACAGAACTGGATGCTGATCGCTTGCGA
GCTTACGATGTCCCTGTGGTGGCAATTAACACGGGGCGGTCCTGCCATCTAGACGCCAAGATGGTGGCGGGCGGTATCCA
CCAATTGGAGCATTGCACCAATCCTAGAGAGTTGGATTTAGTGCTAGTAGAGAATGTCGGAAATCTTGTATGTCCGGCAG
AATTCGAAGTAGGGGAGCATGCCAAAGTTGCCCTACTCAGCGTGACAGAGGGGGAAGATAAGCCGCTGAAATATCCAGTG
ATGTTTCAAGCAGCCGATTGTCTGTTGGTGACCAAGATAGATTTAGTTCCTTATCTAAATATTGATATTGAGCAGATTGT
CCAAAATGTCCGTCAGCTCAATCCCCATGCCACGATTTTGCCAGTGTCTGCCCAAACAGGGACAGGACTTTCTGAATGGT
TTGAGTGGGTTCGTCAGCAGGTTGTCCACCTCAAACGGACTGCAGTCGGTAGTCACTAG

Upstream 100 bases:

>100_bases
TATGCCTGTCCCACGTGTGGAGCCCCCATGGAAGATATCCGGTCCGGCCGCGAACTCAAAATTGACCACATCGAATATTG
TTCTGATTCAGCCCAAACCT

Downstream 100 bases:

>100_bases
TTGTTTGTAAGCAGGTAAAAGATTTCTATGAAGCGACGAAATTTTCTATCCCTATGTTTAGTATTTTTTTGCAGTTTACT
GCTGACGATCAGTTGTAGCC

Product: hydrogenase accessory protein HypB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 232; Mature: 232

Protein sequence:

>232_residues
MHQTVDAALGINLLHANQEGADHNQAHFNEWGVTCFNVMSSPGAGKTVLLEKTLAALSPDLNLAVIEGDMTTELDADRLR
AYDVPVVAINTGRSCHLDAKMVAGGIHQLEHCTNPRELDLVLVENVGNLVCPAEFEVGEHAKVALLSVTEGEDKPLKYPV
MFQAADCLLVTKIDLVPYLNIDIEQIVQNVRQLNPHATILPVSAQTGTGLSEWFEWVRQQVVHLKRTAVGSH

Sequences:

>Translated_232_residues
MHQTVDAALGINLLHANQEGADHNQAHFNEWGVTCFNVMSSPGAGKTVLLEKTLAALSPDLNLAVIEGDMTTELDADRLR
AYDVPVVAINTGRSCHLDAKMVAGGIHQLEHCTNPRELDLVLVENVGNLVCPAEFEVGEHAKVALLSVTEGEDKPLKYPV
MFQAADCLLVTKIDLVPYLNIDIEQIVQNVRQLNPHATILPVSAQTGTGLSEWFEWVRQQVVHLKRTAVGSH
>Mature_232_residues
MHQTVDAALGINLLHANQEGADHNQAHFNEWGVTCFNVMSSPGAGKTVLLEKTLAALSPDLNLAVIEGDMTTELDADRLR
AYDVPVVAINTGRSCHLDAKMVAGGIHQLEHCTNPRELDLVLVENVGNLVCPAEFEVGEHAKVALLSVTEGEDKPLKYPV
MFQAADCLLVTKIDLVPYLNIDIEQIVQNVRQLNPHATILPVSAQTGTGLSEWFEWVRQQVVHLKRTAVGSH

Specific function: Could be involved in nickel binding and accumulation [H]

COG id: COG0378

COG function: function code OK; Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hypB/hupM family [H]

Homologues:

Organism=Escherichia coli, GI1789082, Length=210, Percent_Identity=47.6190476190476, Blast_Score=202, Evalue=1e-53,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR003495
- InterPro:   IPR004392
- InterPro:   IPR012202 [H]

Pfam domain/function: PF02492 cobW [H]

EC number: NA

Molecular weight: Translated: 25323; Mature: 25323

Theoretical pI: Translated: 4.92; Mature: 4.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHQTVDAALGINLLHANQEGADHNQAHFNEWGVTCFNVMSSPGAGKTVLLEKTLAALSPD
CCCCHHHHHCEEEEECCCCCCCCCCCCHHHCCCEEEEHHCCCCCCCEEEHHHHHHHHCCC
LNLAVIEGDMTTELDADRLRAYDVPVVAINTGRSCHLDAKMVAGGIHQLEHCTNPRELDL
CEEEEEECCCCCCCCHHHHEEECCCEEEEECCCCEEECHHHHHHHHHHHHHCCCCCCEEE
VLVENVGNLVCPAEFEVGEHAKVALLSVTEGEDKPLKYPVMFQAADCLLVTKIDLVPYLN
EEEECCCCEECCCCCCCCCCCEEEEEEEECCCCCCEECCEEEECCCEEEEEEECEEEECC
IDIEQIVQNVRQLNPHATILPVSAQTGTGLSEWFEWVRQQVVHLKRTAVGSH
CCHHHHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MHQTVDAALGINLLHANQEGADHNQAHFNEWGVTCFNVMSSPGAGKTVLLEKTLAALSPD
CCCCHHHHHCEEEEECCCCCCCCCCCCHHHCCCEEEEHHCCCCCCCEEEHHHHHHHHCCC
LNLAVIEGDMTTELDADRLRAYDVPVVAINTGRSCHLDAKMVAGGIHQLEHCTNPRELDL
CEEEEEECCCCCCCCHHHHEEECCCEEEEECCCCEEECHHHHHHHHHHHHHCCCCCCEEE
VLVENVGNLVCPAEFEVGEHAKVALLSVTEGEDKPLKYPVMFQAADCLLVTKIDLVPYLN
EEEECCCCEECCCCCCCCCCCEEEEEEEECCCCCCEECCEEEECCCEEEEEEECEEEECC
IDIEQIVQNVRQLNPHATILPVSAQTGTGLSEWFEWVRQQVVHLKRTAVGSH
CCHHHHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8486288 [H]