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The map label for this gene is speB [H]

Identifier: 158335975

GI number: 158335975

Start: 2876119

End: 2877315

Strand: Direct

Name: speB [H]

Synonym: AM1_2833

Alternate gene names: 158335975

Gene position: 2876119-2877315 (Clockwise)

Preceding gene: 158335974

Following gene: 158335976

Centisome position: 44.22

GC content: 51.21

Gene sequence:

>1197_bases
ATGGCTGAAAACTCGACCTTTGGTCCTCCCAATTCTGATCCTAATTTTTCGTCCACTGAGGCCAATCGTGCTTTAGAGAA
AGAAGCACAATTGCCCCTCACGGGCTGGCAACAAGAAGTTGACCGGGGATTAGAACTGGGGTTAGAAGCGGCGGCTAGTA
TTCGCGATCGGAGCATCCCCACCTTCTCGCGAGGCGAGCTGCCCCACTATGCGGGCATCAATACCTTCCTCAAAGCGCCT
TACCTAGAAGATGTGCGTAAAGTCGATGAATACGATATTGCTGTAGTAGGCGTTCCCCATGACTCCGGCACCACTTATCG
TCCCGGTACGCGCTTCGGCCCCCAGGGTATTCGTCGGATTTCAGCCCTGTATACTCCTTATAATTTCGAGCTGGGTATCG
ATTTACGAGAGCAGATCACCCTCTGCGATGTTGGGGATATCTTCACCATCCCCGCCAATAATGAGAAATCTTTTGACCAA
ATTTCCAAAGGAGTCGCCCATATCTTCAGTTCTGGCGCTTTCCCTATCATCTTAGGGGGCGATCATTCCATTGGTTTCCC
CACTGTTCGAGGGGTTTGCCGCCATTTAGGGGACAAGAAAGTCGGTATCATCCACTTCGATCGCCATGTGGATACCCAAG
AAACGGATTTAGACGAGCGCATGCATACCTGCCCTTGGTTTCATGCCACTAACATGGCCAATGCTCCGGCTAAAAACTTA
GTGCAATTAGGCATTGGCGGTTGGCAAGTGCCTCGACAAGGGGTCAAGGTCTGTCGAGAGCGAGCCACGAATATTCTCAC
CGTCACCGATATCACTGAAATTGGACTTGATGCTGCCGTTGACTTCGCCTTAGAACGAGCCTTAGACGGCACAGACTGCG
TCTATATCAGCTTTGATATTGACTGTATTGATGCTGGATTTGTCCCCGGTACCGGCTGGCCAGAACCCGGCGGTCTGATG
CCCCGAGAAGCTCTCTATATGTTGGGCAAAATTATTCAAAAAGCCCCCGTCTGCGGCTTGGAAATCGTTGAAGTGTCACC
CCCTTATGACATCAGCGATATGACCTCGCTCATGGCCACTCGGGTCATTTGCGATACCATGGCCCATCTTGTGCTGTCGG
GGCAACTTCCCCGGCAAAAAGCACCAGACTATATTCATCCTGAAGCCAATATGGCAGTAGGTTCTGAGTGGGTTTAG

Upstream 100 bases:

>100_bases
TTTTAAATTGACACGTCTCATCTTCCTCTAAAATGGCTGAGAAACAACATGAAGAAAGAAATTAACGTGACAAAGTAAAA
ACCCTAAATTTTCCGATATT

Downstream 100 bases:

>100_bases
GCCATGCATGAAACGGATATGACCAAGGCCCTAATTATGACGGTCAAGGACTGGTACGATTCCCAGCCTGAAGATCCACA
AATCACCAAAATTCATTTGG

Product: agmatinase

Products: NA

Alternate protein names: Agmatine ureohydrolase 2; AUH 2 [H]

Number of amino acids: Translated: 398; Mature: 397

Protein sequence:

>398_residues
MAENSTFGPPNSDPNFSSTEANRALEKEAQLPLTGWQQEVDRGLELGLEAAASIRDRSIPTFSRGELPHYAGINTFLKAP
YLEDVRKVDEYDIAVVGVPHDSGTTYRPGTRFGPQGIRRISALYTPYNFELGIDLREQITLCDVGDIFTIPANNEKSFDQ
ISKGVAHIFSSGAFPIILGGDHSIGFPTVRGVCRHLGDKKVGIIHFDRHVDTQETDLDERMHTCPWFHATNMANAPAKNL
VQLGIGGWQVPRQGVKVCRERATNILTVTDITEIGLDAAVDFALERALDGTDCVYISFDIDCIDAGFVPGTGWPEPGGLM
PREALYMLGKIIQKAPVCGLEIVEVSPPYDISDMTSLMATRVICDTMAHLVLSGQLPRQKAPDYIHPEANMAVGSEWV

Sequences:

>Translated_398_residues
MAENSTFGPPNSDPNFSSTEANRALEKEAQLPLTGWQQEVDRGLELGLEAAASIRDRSIPTFSRGELPHYAGINTFLKAP
YLEDVRKVDEYDIAVVGVPHDSGTTYRPGTRFGPQGIRRISALYTPYNFELGIDLREQITLCDVGDIFTIPANNEKSFDQ
ISKGVAHIFSSGAFPIILGGDHSIGFPTVRGVCRHLGDKKVGIIHFDRHVDTQETDLDERMHTCPWFHATNMANAPAKNL
VQLGIGGWQVPRQGVKVCRERATNILTVTDITEIGLDAAVDFALERALDGTDCVYISFDIDCIDAGFVPGTGWPEPGGLM
PREALYMLGKIIQKAPVCGLEIVEVSPPYDISDMTSLMATRVICDTMAHLVLSGQLPRQKAPDYIHPEANMAVGSEWV
>Mature_397_residues
AENSTFGPPNSDPNFSSTEANRALEKEAQLPLTGWQQEVDRGLELGLEAAASIRDRSIPTFSRGELPHYAGINTFLKAPY
LEDVRKVDEYDIAVVGVPHDSGTTYRPGTRFGPQGIRRISALYTPYNFELGIDLREQITLCDVGDIFTIPANNEKSFDQI
SKGVAHIFSSGAFPIILGGDHSIGFPTVRGVCRHLGDKKVGIIHFDRHVDTQETDLDERMHTCPWFHATNMANAPAKNLV
QLGIGGWQVPRQGVKVCRERATNILTVTDITEIGLDAAVDFALERALDGTDCVYISFDIDCIDAGFVPGTGWPEPGGLMP
REALYMLGKIIQKAPVCGLEIVEVSPPYDISDMTSLMATRVICDTMAHLVLSGQLPRQKAPDYIHPEANMAVGSEWV

Specific function: Catalyzes The Formation Of Putrescine From Agmatine. [C]

COG id: COG0010

COG function: function code E; Arginase/agmatinase/formimionoglutamate hydrolase, arginase family

Gene ontology:
GO:0016813: Agmatinase, putative
GO:0046872: Agmatinase, putative
GO:0016787: Agmatinase, putative

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the arginase family. Agmatinase subfamily [H]

Homologues:

Organism=Homo sapiens, GI37537722, Length=281, Percent_Identity=33.8078291814947, Blast_Score=155, Evalue=8e-38,
Organism=Homo sapiens, GI10947139, Length=319, Percent_Identity=24.7648902821317, Blast_Score=82, Evalue=9e-16,
Organism=Homo sapiens, GI4502215, Length=354, Percent_Identity=22.316384180791, Blast_Score=76, Evalue=5e-14,
Organism=Escherichia coli, GI1789306, Length=270, Percent_Identity=30.3703703703704, Blast_Score=125, Evalue=7e-30,
Organism=Saccharomyces cerevisiae, GI6325146, Length=214, Percent_Identity=24.2990654205607, Blast_Score=76, Evalue=7e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006035
- InterPro:   IPR020855 [H]

Pfam domain/function: PF00491 Arginase [H]

EC number: =3.5.3.11 [H]

Molecular weight: Translated: 43625; Mature: 43494

Theoretical pI: Translated: 4.74; Mature: 4.74

Prosite motif: PS01053 ARGINASE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAENSTFGPPNSDPNFSSTEANRALEKEAQLPLTGWQQEVDRGLELGLEAAASIRDRSIP
CCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCC
TFSRGELPHYAGINTFLKAPYLEDVRKVDEYDIAVVGVPHDSGTTYRPGTRFGPQGIRRI
CCCCCCCCCCCCCHHHHCCCHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCCCHHHHHHH
SALYTPYNFELGIDLREQITLCDVGDIFTIPANNEKSFDQISKGVAHIFSSGAFPIILGG
HHHCCCCCEEECCCHHHCEEEEECCCEEEECCCCCHHHHHHHHHHHHHHCCCCEEEEECC
DHSIGFPTVRGVCRHLGDKKVGIIHFDRHVDTQETDLDERMHTCPWFHATNMANAPAKNL
CCCCCCHHHHHHHHHCCCCCEEEEEECCCCCCCCCCHHHHHHHCCCEECCCCCCCCHHHH
VQLGIGGWQVPRQGVKVCRERATNILTVTDITEIGLDAAVDFALERALDGTDCVYISFDI
HHHCCCCCCCCHHHHHHHHHHCCCEEEEECHHHHHHHHHHHHHHHHCCCCCCEEEEEEEE
DCIDAGFVPGTGWPEPGGLMPREALYMLGKIIQKAPVCGLEIVEVSPPYDISDMTSLMAT
EEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHH
RVICDTMAHLVLSGQLPRQKAPDYIHPEANMAVGSEWV
HHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
AENSTFGPPNSDPNFSSTEANRALEKEAQLPLTGWQQEVDRGLELGLEAAASIRDRSIP
CCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCC
TFSRGELPHYAGINTFLKAPYLEDVRKVDEYDIAVVGVPHDSGTTYRPGTRFGPQGIRRI
CCCCCCCCCCCCCHHHHCCCHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCCCHHHHHHH
SALYTPYNFELGIDLREQITLCDVGDIFTIPANNEKSFDQISKGVAHIFSSGAFPIILGG
HHHCCCCCEEECCCHHHCEEEEECCCEEEECCCCCHHHHHHHHHHHHHHCCCCEEEEECC
DHSIGFPTVRGVCRHLGDKKVGIIHFDRHVDTQETDLDERMHTCPWFHATNMANAPAKNL
CCCCCCHHHHHHHHHCCCCCEEEEEECCCCCCCCCCHHHHHHHCCCEECCCCCCCCHHHH
VQLGIGGWQVPRQGVKVCRERATNILTVTDITEIGLDAAVDFALERALDGTDCVYISFDI
HHHCCCCCCCCHHHHHHHHHHCCCEEEEECHHHHHHHHHHHHHHHHCCCCCCEEEEEEEE
DCIDAGFVPGTGWPEPGGLMPREALYMLGKIIQKAPVCGLEIVEVSPPYDISDMTSLMAT
EEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHH
RVICDTMAHLVLSGQLPRQKAPDYIHPEANMAVGSEWV
HHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]