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The map label for this gene is cymR [H]

Identifier: 158335568

GI number: 158335568

Start: 2423644

End: 2424081

Strand: Reverse

Name: cymR [H]

Synonym: AM1_2418

Alternate gene names: 158335568

Gene position: 2424081-2423644 (Counterclockwise)

Preceding gene: 158335569

Following gene: 158335567

Centisome position: 37.27

GC content: 47.03

Gene sequence:

>438_bases
GTGGAATTGTCATGTAAATGTGAATATGCGGTGCTGGCATTGCTGTCACTGGTGGATCACTACCCTCAAGGGGAGCCGCT
ACGAATCCGCCAAATTGCAGCTCAACAACATATTCCCGATCGATATTTAGAACAACTCCTGGCCATTCTGCGCCGTTCAG
GTTTAGTCTGTTCTCAGCGAGGGGCGCGCGGAGGATATTTATTGGCCCGGGAACCTTGGAAAATTACCCTACTAGAAATC
ATTAACTGTATAGAAGGCAGAGATCCGCAATCGAACGCTTTACCCCAAACAGGTCTGACAACGGAGAAAGCGGTGGTCCA
GGAACTTTGGCAAGAAGCGGATCAAGCAGCGAGCAAGATCCTCAAGAATTGTACGTTGCAAGATCTTTGCGATCGTAGAG
ATGCTAAAAAACAAATTGACCTGATGTATTACATCTAA

Upstream 100 bases:

>100_bases
TAGAGCACTAAGAAGGCTAGGCAGGATAATCCCTAAACTCCGATGGAGAACCGGAGTATACTAGGTCCAAGGCTGTTGTT
GCCTCAGGGGGGCTTGCCCT

Downstream 100 bases:

>100_bases
GCTAAGAGCACAGCTCAGCTGCCTGGGCCGCGTTCTCTTCCTTGATTGCACTGATAAGCAGAGACTGTCACTATGCGTAT
TGCCCACGATATTACCGAGC

Product: BadM/Rrf2 family transcriptional regulator

Products: NA

Alternate protein names: Cysteine metabolism repressor [H]

Number of amino acids: Translated: 145; Mature: 145

Protein sequence:

>145_residues
MELSCKCEYAVLALLSLVDHYPQGEPLRIRQIAAQQHIPDRYLEQLLAILRRSGLVCSQRGARGGYLLAREPWKITLLEI
INCIEGRDPQSNALPQTGLTTEKAVVQELWQEADQAASKILKNCTLQDLCDRRDAKKQIDLMYYI

Sequences:

>Translated_145_residues
MELSCKCEYAVLALLSLVDHYPQGEPLRIRQIAAQQHIPDRYLEQLLAILRRSGLVCSQRGARGGYLLAREPWKITLLEI
INCIEGRDPQSNALPQTGLTTEKAVVQELWQEADQAASKILKNCTLQDLCDRRDAKKQIDLMYYI
>Mature_145_residues
MELSCKCEYAVLALLSLVDHYPQGEPLRIRQIAAQQHIPDRYLEQLLAILRRSGLVCSQRGARGGYLLAREPWKITLLEI
INCIEGRDPQSNALPQTGLTTEKAVVQELWQEADQAASKILKNCTLQDLCDRRDAKKQIDLMYYI

Specific function: Master repressor of cysteine metabolism in B.subtilis. Controls the expression of genes involved either in cysteine synthesis from sulfide (cysK), sulfonates (ssu), or methionine (mccAB) or in cystine uptake (tcyP). Activity of CymR is positively regulate

COG id: COG1959

COG function: function code K; Predicted transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH rrf2-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1788880, Length=135, Percent_Identity=32.5925925925926, Blast_Score=70, Evalue=6e-14,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000944 [H]

Pfam domain/function: PF02082 Rrf2 [H]

EC number: NA

Molecular weight: Translated: 16524; Mature: 16524

Theoretical pI: Translated: 7.21; Mature: 7.21

Prosite motif: PS01332 UPF0074

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.1 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
4.1 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELSCKCEYAVLALLSLVDHYPQGEPLRIRQIAAQQHIPDRYLEQLLAILRRSGLVCSQR
CCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCC
GARGGYLLAREPWKITLLEIINCIEGRDPQSNALPQTGLTTEKAVVQELWQEADQAASKI
CCCCCEEEECCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
LKNCTLQDLCDRRDAKKQIDLMYYI
HHCCCHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MELSCKCEYAVLALLSLVDHYPQGEPLRIRQIAAQQHIPDRYLEQLLAILRRSGLVCSQR
CCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCC
GARGGYLLAREPWKITLLEIINCIEGRDPQSNALPQTGLTTEKAVVQELWQEADQAASKI
CCCCCEEEECCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
LKNCTLQDLCDRRDAKKQIDLMYYI
HHCCCHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]