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The map label for this gene is cobF [H]

Identifier: 158335004

GI number: 158335004

Start: 1832254

End: 1832994

Strand: Reverse

Name: cobF [H]

Synonym: AM1_1842

Alternate gene names: 158335004

Gene position: 1832994-1832254 (Counterclockwise)

Preceding gene: 158335006

Following gene: 158335003

Centisome position: 28.18

GC content: 46.29

Gene sequence:

>741_bases
TTGGCAATATCCCCTCAGATTGGTACGTTATATGGGATTGGTGTAGGTCCTGGAGACTCAGATTTAATTAGTGTAAAAGG
CCTCAATCGTCTACAAAATTGTCCTATTGTTGCCTATCCTGCCGGTCTTCAGGGTAAGCCTGGAATTGCCGAACAAATTA
TTTCCCCTTGGTTGTCTTCACAATATCGCTTACCCCTAATCTTTCCTTATGTTCAGGAGCCTGAACAACTGAACGAGGCC
TGGCAGCGAGCGGCAAAAATCGTTTGGAAGTTTCTTGGTAAAGGGCAAGATATTGCCTTTGCCTGTGAAGGCGATATTGG
CATGTACAGTACCTTCACCTATCTCGCTGATACCCTGATCAACCTCCATCCCCAAGCGCTTATCCAACGGATTCCGGGGA
TAAGCTCACCGATGGCGGCAGCGGCAGCCTTGAATGTGCCTCTGACCTACCAGCGCGATCGATTAGCTATTTTGCCGACG
CTCCAAAGACTAGAAAATTTAACAGAAGCACTAACTTGGGCTGATGTCGTGGTCTTGTTTAAGGTGAGCAGCGTTTATCC
ACAGGTTTGGCAAGTTTTAAAACAGCACAACCTCTTACAGTCGAGTTCTATTGTCATCCGAGCCAGTACGGCTGAGCAAG
AAATCTATCATAATCTTGAGCAGTACCCAGACTTAGAACTACCCTATTTTTCTCTCCTGATTATTACCAAGCCTACAGGT
TCAAAATCCAGCTCAGGCTGA

Upstream 100 bases:

>100_bases
ACTGTATTGGGAACAAACCGCCGATAAGATACCCTATAAACTCAAGCTTTGGTGACGATTCCCCATCACTTGGTTATCAC
TATTGGGAGACAACATTATT

Downstream 100 bases:

>100_bases
TAGTCAGGTCATCTTTTTTCTCCGAAGAAGACCTCATCCCAGGAATTCTGTTTTGCGTTAATCGTGGCACCTATCACACT
TCCGAAAATGGATAATTTCT

Product: precorrin-2 methyltransferase

Products: NA

Alternate protein names: S-adenosyl-L-methionine--precorrin-2 methyltransferase; SP2MT [H]

Number of amino acids: Translated: 246; Mature: 245

Protein sequence:

>246_residues
MAISPQIGTLYGIGVGPGDSDLISVKGLNRLQNCPIVAYPAGLQGKPGIAEQIISPWLSSQYRLPLIFPYVQEPEQLNEA
WQRAAKIVWKFLGKGQDIAFACEGDIGMYSTFTYLADTLINLHPQALIQRIPGISSPMAAAAALNVPLTYQRDRLAILPT
LQRLENLTEALTWADVVVLFKVSSVYPQVWQVLKQHNLLQSSSIVIRASTAEQEIYHNLEQYPDLELPYFSLLIITKPTG
SKSSSG

Sequences:

>Translated_246_residues
MAISPQIGTLYGIGVGPGDSDLISVKGLNRLQNCPIVAYPAGLQGKPGIAEQIISPWLSSQYRLPLIFPYVQEPEQLNEA
WQRAAKIVWKFLGKGQDIAFACEGDIGMYSTFTYLADTLINLHPQALIQRIPGISSPMAAAAALNVPLTYQRDRLAILPT
LQRLENLTEALTWADVVVLFKVSSVYPQVWQVLKQHNLLQSSSIVIRASTAEQEIYHNLEQYPDLELPYFSLLIITKPTG
SKSSSG
>Mature_245_residues
AISPQIGTLYGIGVGPGDSDLISVKGLNRLQNCPIVAYPAGLQGKPGIAEQIISPWLSSQYRLPLIFPYVQEPEQLNEAW
QRAAKIVWKFLGKGQDIAFACEGDIGMYSTFTYLADTLINLHPQALIQRIPGISSPMAAAAALNVPLTYQRDRLAILPTL
QRLENLTEALTWADVVVLFKVSSVYPQVWQVLKQHNLLQSSSIVIRASTAEQEIYHNLEQYPDLELPYFSLLIITKPTGS
KSSSG

Specific function: Methylates precorrin-2 at the C-20 position to produce precorrin-3A [H]

COG id: COG2243

COG function: function code H; Precorrin-2 methylase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the precorrin methyltransferase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000878
- InterPro:   IPR014777
- InterPro:   IPR012382
- InterPro:   IPR006364 [H]

Pfam domain/function: PF00590 TP_methylase [H]

EC number: =2.1.1.130 [H]

Molecular weight: Translated: 27123; Mature: 26991

Theoretical pI: Translated: 6.26; Mature: 6.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAISPQIGTLYGIGVGPGDSDLISVKGLNRLQNCPIVAYPAGLQGKPGIAEQIISPWLSS
CCCCCCCCCEEEECCCCCCCCEEEECCCHHHCCCCEEEECCCCCCCCCHHHHHHHHHHCC
QYRLPLIFPYVQEPEQLNEAWQRAAKIVWKFLGKGQDIAFACEGDIGMYSTFTYLADTLI
CCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHH
NLHPQALIQRIPGISSPMAAAAALNVPLTYQRDRLAILPTLQRLENLTEALTWADVVVLF
CCCHHHHHHHCCCCCCCHHHHHHCCCCCEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
KVSSVYPQVWQVLKQHNLLQSSSIVIRASTAEQEIYHNLEQYPDLELPYFSLLIITKPTG
HHHHHHHHHHHHHHHHCCCCCCCEEEEECCHHHHHHHHHHHCCCCCCCEEEEEEEECCCC
SKSSSG
CCCCCC
>Mature Secondary Structure 
AISPQIGTLYGIGVGPGDSDLISVKGLNRLQNCPIVAYPAGLQGKPGIAEQIISPWLSS
CCCCCCCCEEEECCCCCCCCEEEECCCHHHCCCCEEEECCCCCCCCCHHHHHHHHHHCC
QYRLPLIFPYVQEPEQLNEAWQRAAKIVWKFLGKGQDIAFACEGDIGMYSTFTYLADTLI
CCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHH
NLHPQALIQRIPGISSPMAAAAALNVPLTYQRDRLAILPTLQRLENLTEALTWADVVVLF
CCCHHHHHHHCCCCCCCHHHHHHCCCCCEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
KVSSVYPQVWQVLKQHNLLQSSSIVIRASTAEQEIYHNLEQYPDLELPYFSLLIITKPTG
HHHHHHHHHHHHHHHHCCCCCCCEEEEECCHHHHHHHHHHHCCCCCCCEEEEEEEECCCC
SKSSSG
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]