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The map label for this gene is cph2 [H]

Identifier: 158335003

GI number: 158335003

Start: 1829811

End: 1831703

Strand: Reverse

Name: cph2 [H]

Synonym: AM1_1841

Alternate gene names: 158335003

Gene position: 1831703-1829811 (Counterclockwise)

Preceding gene: 158335004

Following gene: 158335001

Centisome position: 28.16

GC content: 47.81

Gene sequence:

>1893_bases
ATGAAGGCTATTTCTACACATTCATCTCAGCAACTCGCGGTTAATCATGCGGCCAACAACACACCGCAATTTTTGACGCA
AGTCGGTCAACCCAAACCTATACCTGGCAGATTTGCGCAACTGTTGGCTCCATTAACCCAACAAACCTTTCGTCAAGTGG
TTCAGCAAGTCCAACAGGAACTCAGCATTGTCCATCAAACCCTATGCATGTTGGAGGATCAGGGATTCCAGGGTGTTTTG
AATGACTTACTCCATTCCATGGCCCTCAAAATAGGTGAACTGCTCGATGCCGATCGAACCACGATTTTTATGTTTGATGC
GGAGCAGCAAGAGCTATGGTCTATGGTCCAAGAAGAGAGTGGGTCGAACTCCATTGAAATTCGTCTTCCGGCTAATCGGG
GGATTGCGGGTCACGTGGCAACTCACCAAGAGACCCTTAATATTCCCTATGACTTCTATGATGATCCCCGCTCGGAAGAA
GCCAAAAAGCAAGATCGGCGCACAGGGTACCGAACCTATACCCTATTGGCAATCCCGGTTTTAGATCAACAGGGACAGCT
ACTGGCCGTTGTCCAAATGTTGAACAAAATCCGTCCAGGTGTACATCCCACCCTTCCCATCCAGGATCGAATTCATCACC
AGGGATTTGGGGCAGCTGATGAGAAAATTTTTGCAGAATTTGTAGAAGTGATCGGTCTTTTACTTGAGAGTTCTAAAGCG
TTCTATGCCGCAGCCCAAAAACAGCGCGCTGCCAATGCATTGATGGCCTCTACTCAAGTGCTAGGCCAAAGCGGCTTATC
TCTACAGGAGACTCTTCTTCACATCATGGCGGAAGCCAAACAATTAATGCAGGCTGAGCACTCCATTTTGTGGCTCGTGG
ATCAAGATCATCATCGGCTGTGGACCTATGCCAATATTCCCCATCAACAAATTCCTCTAGGGACAGGGCTTTTGGGTAAA
TTGGTGGAGACTCAGCACCCCCTGAATTATGCCTTTAACCATCTGCCCTTATCCACTCATCAATTTGGGTGTAATACCCC
CCTTTATAGTGTGTTGTGCATGCCTGTTCTGAACGCCCATGGCAAACTGATCGCCATTGCACAATTGGCGAATAAATATC
GTCCTAGTATTGCTAACGCAGAATCTAGACGAGGAGAAGTGCCGGAGCGGTATCGGATAAATTTCAGTAAGACAGATGAG
ACCTTTTTGATGGCCTTTAATACCCAAGCCGGCAGTATTTTAGACCGTGCCATCATTAATGCCGATTTAGAAGACAAAGT
CCGAGAGAGGACCCAGGCCCTTTATGATCGTAATTTACAGCTGCAACAAGAAATTGAAGAGCGCCATCGTGCAGAAGCAA
AACTGAAGCAACTGAATCAGCAATTACAACAGCTCAGCCGCATTGATGGACTGACGTCGATCCATAATCGCCGTAGCTTT
GATGAATCCTTAGACAAGGAGTGGAGGCGACTGCGGCGCGAACAACAGCCCTTGTCCATTATTTTGTGTGACGTAGACCA
TTTCAAACAATATAACGATACCTATGGGCATCAGGCGGGAGATACCTGTTTGCAGGAAGTTGCCTTAGCCATCGATAAAA
GCGTTAAACGTCCTGCGGATATGGTAGCCCGCTATGGCGGGGAAGAGTTTGTAGTGTTGCTTCCCAATACGCCCCTTCCT
GGCGCCACCCACATTGCTGAGATGATACGCACAGCTATCGAAGTCCTCAGGATTCCCCATAAGACCTCATCTGCTAGCGA
CCAGGTCACCCTGAGTTTAGGAGTAGCAACTGTCATCCCTAATACTCAACAGACCTACACAGAATTATTGGAAGCAGCCG
ATGCTGCCCTTTATCGGGCTAAACAACAAGGTCGCAATCGGGTTATTTCGTGA

Upstream 100 bases:

>100_bases
TATTTGATTTAGATTAAGCACTCTTTCATCTGGATTGTTTCTGGGTGGGTGGCCTTGGGTCCTTACCTGACAGTCTGCTG
GTCTTGCGTATAGGTTTGGT

Downstream 100 bases:

>100_bases
CTATTTAGGGATTTTAGTAGCTTGAAGGATTGGCCGATAAACCATGAACAGAATCCGTCACAGACGGCTGAGAAGTACCT
GCCCACCTCAAGTAATCCTC

Product: diguanylate cyclase

Products: NA

Alternate protein names: Bacteriophytochrome cph2 [H]

Number of amino acids: Translated: 630; Mature: 630

Protein sequence:

>630_residues
MKAISTHSSQQLAVNHAANNTPQFLTQVGQPKPIPGRFAQLLAPLTQQTFRQVVQQVQQELSIVHQTLCMLEDQGFQGVL
NDLLHSMALKIGELLDADRTTIFMFDAEQQELWSMVQEESGSNSIEIRLPANRGIAGHVATHQETLNIPYDFYDDPRSEE
AKKQDRRTGYRTYTLLAIPVLDQQGQLLAVVQMLNKIRPGVHPTLPIQDRIHHQGFGAADEKIFAEFVEVIGLLLESSKA
FYAAAQKQRAANALMASTQVLGQSGLSLQETLLHIMAEAKQLMQAEHSILWLVDQDHHRLWTYANIPHQQIPLGTGLLGK
LVETQHPLNYAFNHLPLSTHQFGCNTPLYSVLCMPVLNAHGKLIAIAQLANKYRPSIANAESRRGEVPERYRINFSKTDE
TFLMAFNTQAGSILDRAIINADLEDKVRERTQALYDRNLQLQQEIEERHRAEAKLKQLNQQLQQLSRIDGLTSIHNRRSF
DESLDKEWRRLRREQQPLSIILCDVDHFKQYNDTYGHQAGDTCLQEVALAIDKSVKRPADMVARYGGEEFVVLLPNTPLP
GATHIAEMIRTAIEVLRIPHKTSSASDQVTLSLGVATVIPNTQQTYTELLEAADAALYRAKQQGRNRVIS

Sequences:

>Translated_630_residues
MKAISTHSSQQLAVNHAANNTPQFLTQVGQPKPIPGRFAQLLAPLTQQTFRQVVQQVQQELSIVHQTLCMLEDQGFQGVL
NDLLHSMALKIGELLDADRTTIFMFDAEQQELWSMVQEESGSNSIEIRLPANRGIAGHVATHQETLNIPYDFYDDPRSEE
AKKQDRRTGYRTYTLLAIPVLDQQGQLLAVVQMLNKIRPGVHPTLPIQDRIHHQGFGAADEKIFAEFVEVIGLLLESSKA
FYAAAQKQRAANALMASTQVLGQSGLSLQETLLHIMAEAKQLMQAEHSILWLVDQDHHRLWTYANIPHQQIPLGTGLLGK
LVETQHPLNYAFNHLPLSTHQFGCNTPLYSVLCMPVLNAHGKLIAIAQLANKYRPSIANAESRRGEVPERYRINFSKTDE
TFLMAFNTQAGSILDRAIINADLEDKVRERTQALYDRNLQLQQEIEERHRAEAKLKQLNQQLQQLSRIDGLTSIHNRRSF
DESLDKEWRRLRREQQPLSIILCDVDHFKQYNDTYGHQAGDTCLQEVALAIDKSVKRPADMVARYGGEEFVVLLPNTPLP
GATHIAEMIRTAIEVLRIPHKTSSASDQVTLSLGVATVIPNTQQTYTELLEAADAALYRAKQQGRNRVIS
>Mature_630_residues
MKAISTHSSQQLAVNHAANNTPQFLTQVGQPKPIPGRFAQLLAPLTQQTFRQVVQQVQQELSIVHQTLCMLEDQGFQGVL
NDLLHSMALKIGELLDADRTTIFMFDAEQQELWSMVQEESGSNSIEIRLPANRGIAGHVATHQETLNIPYDFYDDPRSEE
AKKQDRRTGYRTYTLLAIPVLDQQGQLLAVVQMLNKIRPGVHPTLPIQDRIHHQGFGAADEKIFAEFVEVIGLLLESSKA
FYAAAQKQRAANALMASTQVLGQSGLSLQETLLHIMAEAKQLMQAEHSILWLVDQDHHRLWTYANIPHQQIPLGTGLLGK
LVETQHPLNYAFNHLPLSTHQFGCNTPLYSVLCMPVLNAHGKLIAIAQLANKYRPSIANAESRRGEVPERYRINFSKTDE
TFLMAFNTQAGSILDRAIINADLEDKVRERTQALYDRNLQLQQEIEERHRAEAKLKQLNQQLQQLSRIDGLTSIHNRRSF
DESLDKEWRRLRREQQPLSIILCDVDHFKQYNDTYGHQAGDTCLQEVALAIDKSVKRPADMVARYGGEEFVVLLPNTPLP
GATHIAEMIRTAIEVLRIPHKTSSASDQVTLSLGVATVIPNTQQTYTELLEAADAALYRAKQQGRNRVIS

Specific function: Photoreceptor which exists in two forms that are reversibly interconvertible by light:the R form that absorbs maximally in the red region of the spectrum and the FR form that absorbs maximally in the far-red region [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Integral Membrane Protein [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 GGDEF domains [H]

Homologues:

Organism=Homo sapiens, GI61744432, Length=381, Percent_Identity=25.9842519685039, Blast_Score=100, Evalue=8e-21,
Organism=Homo sapiens, GI61744430, Length=381, Percent_Identity=25.9842519685039, Blast_Score=99, Evalue=1e-20,
Organism=Homo sapiens, GI61744435, Length=381, Percent_Identity=25.9842519685039, Blast_Score=99, Evalue=1e-20,
Organism=Homo sapiens, GI116536085, Length=340, Percent_Identity=24.4117647058824, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI5729972, Length=171, Percent_Identity=31.5789473684211, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI194595488, Length=171, Percent_Identity=31.5789473684211, Blast_Score=77, Evalue=3e-14,
Organism=Escherichia coli, GI1786584, Length=185, Percent_Identity=36.2162162162162, Blast_Score=120, Evalue=2e-28,
Organism=Escherichia coli, GI145693134, Length=202, Percent_Identity=34.6534653465347, Blast_Score=117, Evalue=3e-27,
Organism=Escherichia coli, GI87081881, Length=175, Percent_Identity=40, Blast_Score=115, Evalue=1e-26,
Organism=Escherichia coli, GI87082007, Length=185, Percent_Identity=36.7567567567568, Blast_Score=105, Evalue=9e-24,
Organism=Escherichia coli, GI1787262, Length=161, Percent_Identity=39.1304347826087, Blast_Score=105, Evalue=1e-23,
Organism=Escherichia coli, GI1787802, Length=179, Percent_Identity=34.0782122905028, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI1788381, Length=173, Percent_Identity=32.9479768786127, Blast_Score=88, Evalue=2e-18,
Organism=Escherichia coli, GI1787816, Length=164, Percent_Identity=34.7560975609756, Blast_Score=87, Evalue=4e-18,
Organism=Escherichia coli, GI1788085, Length=173, Percent_Identity=32.9479768786127, Blast_Score=82, Evalue=9e-17,
Organism=Escherichia coli, GI1787541, Length=182, Percent_Identity=30.7692307692308, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI87081974, Length=159, Percent_Identity=29.559748427673, Blast_Score=69, Evalue=7e-13,
Organism=Escherichia coli, GI87081977, Length=174, Percent_Identity=29.3103448275862, Blast_Score=66, Evalue=8e-12,
Organism=Escherichia coli, GI1787056, Length=161, Percent_Identity=30.4347826086957, Blast_Score=66, Evalue=8e-12,
Organism=Escherichia coli, GI1788956, Length=223, Percent_Identity=25.5605381165919, Blast_Score=63, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI193202333, Length=177, Percent_Identity=32.2033898305085, Blast_Score=72, Evalue=8e-13,
Organism=Drosophila melanogaster, GI161076953, Length=364, Percent_Identity=23.9010989010989, Blast_Score=102, Evalue=1e-21,
Organism=Drosophila melanogaster, GI161076955, Length=364, Percent_Identity=23.9010989010989, Blast_Score=101, Evalue=1e-21,
Organism=Drosophila melanogaster, GI281361762, Length=228, Percent_Identity=25, Blast_Score=79, Evalue=7e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR003018
- InterPro:   IPR016132
- InterPro:   IPR001294
- InterPro:   IPR013515 [H]

Pfam domain/function: PF00563 EAL; PF01590 GAF; PF00990 GGDEF; PF00360 Phytochrome [H]

EC number: NA

Molecular weight: Translated: 70967; Mature: 70967

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAISTHSSQQLAVNHAANNTPQFLTQVGQPKPIPGRFAQLLAPLTQQTFRQVVQQVQQE
CCCCCCCCCCCEEHHHCCCCCHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
LSIVHQTLCMLEDQGFQGVLNDLLHSMALKIGELLDADRTTIFMFDAEQQELWSMVQEES
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHCC
GSNSIEIRLPANRGIAGHVATHQETLNIPYDFYDDPRSEEAKKQDRRTGYRTYTLLAIPV
CCCEEEEEECCCCCCCCCEECCHHHCCCCCCCCCCCCCHHHHHHHHHCCCEEEEEEEEEE
LDQQGQLLAVVQMLNKIRPGVHPTLPIQDRIHHQGFGAADEKIFAEFVEVIGLLLESSKA
ECCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCHH
FYAAAQKQRAANALMASTQVLGQSGLSLQETLLHIMAEAKQLMQAEHSILWLVDQDHHRL
HHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCEE
WTYANIPHQQIPLGTGLLGKLVETQHPLNYAFNHLPLSTHQFGCNTPLYSVLCMPVLNAH
EEEECCCCHHCCCCCHHHHHHHHCCCCHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCC
GKLIAIAQLANKYRPSIANAESRRGEVPERYRINFSKTDETFLMAFNTQAGSILDRAIIN
CCEEHHHHHHHHHCCCCCCCHHHCCCCCHHEEEEECCCCCEEEEEECCCHHHHHHHHHHC
ADLEDKVRERTQALYDRNLQLQQEIEERHRAEAKLKQLNQQLQQLSRIDGLTSIHNRRSF
CCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
DESLDKEWRRLRREQQPLSIILCDVDHFKQYNDTYGHQAGDTCLQEVALAIDKSVKRPAD
HHHHHHHHHHHHHHCCCCEEEEECHHHHHHHCHHCCCCHHHHHHHHHHHHHHHHHCCHHH
MVARYGGEEFVVLLPNTPLPGATHIAEMIRTAIEVLRIPHKTSSASDQVTLSLGVATVIP
HHHHCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECHHEECC
NTQQTYTELLEAADAALYRAKQQGRNRVIS
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MKAISTHSSQQLAVNHAANNTPQFLTQVGQPKPIPGRFAQLLAPLTQQTFRQVVQQVQQE
CCCCCCCCCCCEEHHHCCCCCHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
LSIVHQTLCMLEDQGFQGVLNDLLHSMALKIGELLDADRTTIFMFDAEQQELWSMVQEES
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHCC
GSNSIEIRLPANRGIAGHVATHQETLNIPYDFYDDPRSEEAKKQDRRTGYRTYTLLAIPV
CCCEEEEEECCCCCCCCCEECCHHHCCCCCCCCCCCCCHHHHHHHHHCCCEEEEEEEEEE
LDQQGQLLAVVQMLNKIRPGVHPTLPIQDRIHHQGFGAADEKIFAEFVEVIGLLLESSKA
ECCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCHH
FYAAAQKQRAANALMASTQVLGQSGLSLQETLLHIMAEAKQLMQAEHSILWLVDQDHHRL
HHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCEE
WTYANIPHQQIPLGTGLLGKLVETQHPLNYAFNHLPLSTHQFGCNTPLYSVLCMPVLNAH
EEEECCCCHHCCCCCHHHHHHHHCCCCHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCC
GKLIAIAQLANKYRPSIANAESRRGEVPERYRINFSKTDETFLMAFNTQAGSILDRAIIN
CCEEHHHHHHHHHCCCCCCCHHHCCCCCHHEEEEECCCCCEEEEEECCCHHHHHHHHHHC
ADLEDKVRERTQALYDRNLQLQQEIEERHRAEAKLKQLNQQLQQLSRIDGLTSIHNRRSF
CCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
DESLDKEWRRLRREQQPLSIILCDVDHFKQYNDTYGHQAGDTCLQEVALAIDKSVKRPAD
HHHHHHHHHHHHHHCCCCEEEEECHHHHHHHCHHCCCCHHHHHHHHHHHHHHHHHCCHHH
MVARYGGEEFVVLLPNTPLPGATHIAEMIRTAIEVLRIPHKTSSASDQVTLSLGVATVIP
HHHHCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECHHEECC
NTQQTYTELLEAADAALYRAKQQGRNRVIS
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231; 10978170; 11063585 [H]