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The map label for this gene is cph2 [H]

Identifier: 158334802

GI number: 158334802

Start: 1605817

End: 1606755

Strand: Direct

Name: cph2 [H]

Synonym: AM1_1639

Alternate gene names: 158334802

Gene position: 1605817-1606755 (Clockwise)

Preceding gene: 158334801

Following gene: 158334808

Centisome position: 24.69

GC content: 44.09

Gene sequence:

>939_bases
ATGAGTCAGCAATCCATCATCTTAATTGCAGAGCCTGATCAAGAAATCAGTAATCATATAGCCCAACTTCTGGAGAAGGA
TGGTCATCTAGTGATGACCACATCCAACGGGGAAGAGTGTCTAGAAGCATACAAAAGCATAATGCCGAACCTTGTGATTC
TAGACGCCATGATGCCCAAGATAAACGGTTTTGAATGTTGCAGAAAACTTTTGAAATTATCTAGTGGTTCTCCCCCCCTA
ACCCTAATAATTACAGGGTTAGACGAAGAGGAATCAGTGAATTTAGCTTTTGAGAGTGGCGCATCTGATTTCATTACCAA
ACCTATTCGCTGGCCTATTCTGAAGCAGCGTGTGCGTATCCATTTTGAGAATAATCGACTTAAGAGACAACTCGAAGAGA
CAACTCAAAAACTGCTCCAACTCTCCTCTATGGATGAGTTTAAGCAACTGACCAATCGACAGTTTTTTCTAAAACAAATC
CAAGTTGAATGGCTTCGGATGGTCAGAGAGGAATCTCATCTATCCCTGATGGTTTGCGAGATTGATGGCTTCGAAACTTA
CGCTGATACCTACGGCCATATACAAGCCGACCAATGTTTATCCCAAGTCGATGGGGCCATCCATCAGAGTCTCAATCGTC
CGGCTGACCTGATTACCCGATATGGTGGCGGGAAAATTGCAGCCCTTCTCCCAAATACATCTTTAGAAGGGTCCCTCCAC
ATCACAGAGAAAATTCGAGGAGCTGTAGCTGCTCTGGCCATTCCCCATCAATCTAATGCTTTCTCAGATATCATCACGAT
TAGCTTGGGGATTGCTAGTGTGCTTCCTTGTACTCAATTGATGGGGGCTGGAAGCTTTTATCAATCTGCTGATAAAGCCC
TGTCTAAAGCCAAATCTGAAGGAGGAGATCGGATAGTAGTGGGTACTCCGATAGATTGA

Upstream 100 bases:

>100_bases
ATCATTTGTGCTCTAACAACACGTACTGCAAGACTCTAAATCCTTTCGCCTCGTGAAGATGACTCAGGACAATTTATTCT
CCTTAGCTGACAGAGATATC

Downstream 100 bases:

>100_bases
TGCCGCTGTATCTTTATGGGGGGCAGGGAAGTGTTGACGTTGGTCTGGTGAAAAAGAACACCTAAATCTTGATATCTACT
GAGACGACCCAACCTATTTC

Product: diguanylate cyclase

Products: NA

Alternate protein names: Bacteriophytochrome cph2 [H]

Number of amino acids: Translated: 312; Mature: 311

Protein sequence:

>312_residues
MSQQSIILIAEPDQEISNHIAQLLEKDGHLVMTTSNGEECLEAYKSIMPNLVILDAMMPKINGFECCRKLLKLSSGSPPL
TLIITGLDEEESVNLAFESGASDFITKPIRWPILKQRVRIHFENNRLKRQLEETTQKLLQLSSMDEFKQLTNRQFFLKQI
QVEWLRMVREESHLSLMVCEIDGFETYADTYGHIQADQCLSQVDGAIHQSLNRPADLITRYGGGKIAALLPNTSLEGSLH
ITEKIRGAVAALAIPHQSNAFSDIITISLGIASVLPCTQLMGAGSFYQSADKALSKAKSEGGDRIVVGTPID

Sequences:

>Translated_312_residues
MSQQSIILIAEPDQEISNHIAQLLEKDGHLVMTTSNGEECLEAYKSIMPNLVILDAMMPKINGFECCRKLLKLSSGSPPL
TLIITGLDEEESVNLAFESGASDFITKPIRWPILKQRVRIHFENNRLKRQLEETTQKLLQLSSMDEFKQLTNRQFFLKQI
QVEWLRMVREESHLSLMVCEIDGFETYADTYGHIQADQCLSQVDGAIHQSLNRPADLITRYGGGKIAALLPNTSLEGSLH
ITEKIRGAVAALAIPHQSNAFSDIITISLGIASVLPCTQLMGAGSFYQSADKALSKAKSEGGDRIVVGTPID
>Mature_311_residues
SQQSIILIAEPDQEISNHIAQLLEKDGHLVMTTSNGEECLEAYKSIMPNLVILDAMMPKINGFECCRKLLKLSSGSPPLT
LIITGLDEEESVNLAFESGASDFITKPIRWPILKQRVRIHFENNRLKRQLEETTQKLLQLSSMDEFKQLTNRQFFLKQIQ
VEWLRMVREESHLSLMVCEIDGFETYADTYGHIQADQCLSQVDGAIHQSLNRPADLITRYGGGKIAALLPNTSLEGSLHI
TEKIRGAVAALAIPHQSNAFSDIITISLGIASVLPCTQLMGAGSFYQSADKALSKAKSEGGDRIVVGTPID

Specific function: Photoreceptor which exists in two forms that are reversibly interconvertible by light:the R form that absorbs maximally in the red region of the spectrum and the FR form that absorbs maximally in the far-red region [H]

COG id: COG3706

COG function: function code T; Response regulator containing a CheY-like receiver domain and a GGDEF domain

Gene ontology:

Cell location: Integral Membrane Protein [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 GGDEF domains [H]

Homologues:

Organism=Escherichia coli, GI1787262, Length=163, Percent_Identity=30.0613496932515, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI87081881, Length=186, Percent_Identity=27.4193548387097, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1786584, Length=175, Percent_Identity=26.8571428571429, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1790860, Length=107, Percent_Identity=32.7102803738318, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI145693134, Length=166, Percent_Identity=28.9156626506024, Blast_Score=65, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR003018
- InterPro:   IPR016132
- InterPro:   IPR001294
- InterPro:   IPR013515 [H]

Pfam domain/function: PF00563 EAL; PF01590 GAF; PF00990 GGDEF; PF00360 Phytochrome [H]

EC number: NA

Molecular weight: Translated: 34539; Mature: 34408

Theoretical pI: Translated: 5.40; Mature: 5.40

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQQSIILIAEPDQEISNHIAQLLEKDGHLVMTTSNGEECLEAYKSIMPNLVILDAMMPK
CCCCCEEEEECCCHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHCCCEEEHHHHCCC
INGFECCRKLLKLSSGSPPLTLIITGLDEEESVNLAFESGASDFITKPIRWPILKQRVRI
CCHHHHHHHHHHHCCCCCCEEEEEECCCCCCCEEEEEECCCHHHHCCCCCCHHHHHHHHE
HFENNRLKRQLEETTQKLLQLSSMDEFKQLTNRQFFLKQIQVEWLRMVREESHLSLMVCE
EECCHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEE
IDGFETYADTYGHIQADQCLSQVDGAIHQSLNRPADLITRYGGGKIAALLPNTSLEGSLH
ECCCHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHCCCCEEEEEECCCCCCCCEE
ITEKIRGAVAALAIPHQSNAFSDIITISLGIASVLPCTQLMGAGSFYQSADKALSKAKSE
HHHHHHHHHHHEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHC
GGDRIVVGTPID
CCCEEEEECCCC
>Mature Secondary Structure 
SQQSIILIAEPDQEISNHIAQLLEKDGHLVMTTSNGEECLEAYKSIMPNLVILDAMMPK
CCCCEEEEECCCHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHCCCEEEHHHHCCC
INGFECCRKLLKLSSGSPPLTLIITGLDEEESVNLAFESGASDFITKPIRWPILKQRVRI
CCHHHHHHHHHHHCCCCCCEEEEEECCCCCCCEEEEEECCCHHHHCCCCCCHHHHHHHHE
HFENNRLKRQLEETTQKLLQLSSMDEFKQLTNRQFFLKQIQVEWLRMVREESHLSLMVCE
EECCHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEE
IDGFETYADTYGHIQADQCLSQVDGAIHQSLNRPADLITRYGGGKIAALLPNTSLEGSLH
ECCCHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHCCCCEEEEEECCCCCCCCEE
ITEKIRGAVAALAIPHQSNAFSDIITISLGIASVLPCTQLMGAGSFYQSADKALSKAKSE
HHHHHHHHHHHEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHC
GGDRIVVGTPID
CCCEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231; 10978170; 11063585 [H]