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The map label for this gene is acr3

Identifier: 158333787

GI number: 158333787

Start: 582108

End: 583259

Strand: Reverse

Name: acr3

Synonym: AM1_0595

Alternate gene names: NA

Gene position: 583259-582108 (Counterclockwise)

Preceding gene: 158333788

Following gene: 158333786

Centisome position: 8.97

GC content: 48.7

Gene sequence:

>1152_bases
ATGACCACTCAAAAAACTCGATTTCCCCCACCAGTCCAGGCAGGGGGCCAGCTTAATGTCTTTGAACGCTACCTCACCCT
GTGGGTCGGTCTATGCATTGGTGTGGGGATTCTTTTGGGACGCATTGCCCCTGGAATTGCAGTGAGCCTAAATGCTGCCA
GTATTCACCAGGTCTCTATCCCCATTGCGGTGTGTCTCTTTTTTATGATGTATCCCATCATGGTCAAGATTGATTTTAGC
CAAGCTCGCCGAGCAGCTCGCACCCCAAAACCAGTGCTATTAACCCTTGGCATCAATTGGCTCGTCAAACCCTTCACCAT
GGTTATATTTGCGCAGTTCTTTCTAGGACAGCTCTTTGCCCCACTCCTGCAAGGGACTGAACTTGTTCGCGGGAGTGATA
TAACCTTAGCCAATTCCTACATTGCTGGCGCTATTTTATTAGGGATTGCCCCCTGCACAGCCATGGTCTTGATGTGGGGA
TATCTGTCCTACAGCAATCAGGGACATACCTTAGTAATGGTTGCCGTCAATTCTCTAGCCATGCTTTTTTTGTACGCCCC
ATTGGGACGTTGGCTATTAGCAGCCAATGATTTAGACGTGCCTTGGCAGACCATCGTGCTATCTGTATTGATCTATGTCG
GCTTACCTTTAATCGCGGGCATGAGTTCTCGACACTGGATTCTGAAGCACCAAGGTCAACAGTGGTTCGAACAAGTTTTT
CTCAAAAGACTCAGTCCCATGGCCGTGATCGCCCTTTTGGTGACCTTGGTGCTATTGTTCGCCCTCAAAGGGGAATTAAT
CGTGAACAACCCGCTACATATTGTTCTGATTGCAGTTCCACTCTTTTTACAAACGAACTTTATCTTTCTCATAACCTATG
TCATCGCTCAAAAGTTGGGATTAACCTATGAGGATGCAGCCCCAGCAGCGCTGATTGGAGCCAGCAATCACTTTGAGGTC
GCCATTGCCACCGCTGTGATGCTATTCGGACTAAATTCGGGGGCAGCCCTAGCCACAGTGGTTGGAGTTCTGATCGAAGT
CCCCGTTATGCTGGCTTTGGTTGAGGTCTGTAAGCGCACGGCTTTTTGGTTCCCCAGAGATCCTGAAAAAGCGACGCTTT
TAGATCCTCGTTGTTCTCGTCCTTTGGCTTAA

Upstream 100 bases:

>100_bases
CGGCGTCTTGGCAGAAGAAATATCCGTAGGCAAAAGTTAGATCGTTTTTGATTCTTAAAAATTTTCCAAGTTGAGCTATT
TCTAGAACACTTCACCCGTC

Downstream 100 bases:

>100_bases
TTCACATTCCTGGGAGTAAATGATGAAACGCATCATGTTTGTTTGTAAGCATAATTCGCGCCGTTCCCACATGGCTGAGG
GTTATGCCCGATCAATGGCA

Product: arsenical-resistance protein ACR3

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 383; Mature: 382

Protein sequence:

>383_residues
MTTQKTRFPPPVQAGGQLNVFERYLTLWVGLCIGVGILLGRIAPGIAVSLNAASIHQVSIPIAVCLFFMMYPIMVKIDFS
QARRAARTPKPVLLTLGINWLVKPFTMVIFAQFFLGQLFAPLLQGTELVRGSDITLANSYIAGAILLGIAPCTAMVLMWG
YLSYSNQGHTLVMVAVNSLAMLFLYAPLGRWLLAANDLDVPWQTIVLSVLIYVGLPLIAGMSSRHWILKHQGQQWFEQVF
LKRLSPMAVIALLVTLVLLFALKGELIVNNPLHIVLIAVPLFLQTNFIFLITYVIAQKLGLTYEDAAPAALIGASNHFEV
AIATAVMLFGLNSGAALATVVGVLIEVPVMLALVEVCKRTAFWFPRDPEKATLLDPRCSRPLA

Sequences:

>Translated_383_residues
MTTQKTRFPPPVQAGGQLNVFERYLTLWVGLCIGVGILLGRIAPGIAVSLNAASIHQVSIPIAVCLFFMMYPIMVKIDFS
QARRAARTPKPVLLTLGINWLVKPFTMVIFAQFFLGQLFAPLLQGTELVRGSDITLANSYIAGAILLGIAPCTAMVLMWG
YLSYSNQGHTLVMVAVNSLAMLFLYAPLGRWLLAANDLDVPWQTIVLSVLIYVGLPLIAGMSSRHWILKHQGQQWFEQVF
LKRLSPMAVIALLVTLVLLFALKGELIVNNPLHIVLIAVPLFLQTNFIFLITYVIAQKLGLTYEDAAPAALIGASNHFEV
AIATAVMLFGLNSGAALATVVGVLIEVPVMLALVEVCKRTAFWFPRDPEKATLLDPRCSRPLA
>Mature_382_residues
TTQKTRFPPPVQAGGQLNVFERYLTLWVGLCIGVGILLGRIAPGIAVSLNAASIHQVSIPIAVCLFFMMYPIMVKIDFSQ
ARRAARTPKPVLLTLGINWLVKPFTMVIFAQFFLGQLFAPLLQGTELVRGSDITLANSYIAGAILLGIAPCTAMVLMWGY
LSYSNQGHTLVMVAVNSLAMLFLYAPLGRWLLAANDLDVPWQTIVLSVLIYVGLPLIAGMSSRHWILKHQGQQWFEQVFL
KRLSPMAVIALLVTLVLLFALKGELIVNNPLHIVLIAVPLFLQTNFIFLITYVIAQKLGLTYEDAAPAALIGASNHFEVA
IATAVMLFGLNSGAALATVVGVLIEVPVMLALVEVCKRTAFWFPRDPEKATLLDPRCSRPLA

Specific function: Unknown

COG id: COG0798

COG function: function code P; Arsenite efflux pump ACR3 and related permeases

Gene ontology:
GO:0006814: Arsenical-resistance protein ACR3, putative
GO:0008508: Arsenical-resistance protein ACR3, putative
GO:0016020: Arsenical-resistance protein ACR3, putative
GO:0016021: Arsenical-resistance protein ACR3, putative

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ACR3 family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6325459, Length=339, Percent_Identity=26.5486725663717, Blast_Score=96, Evalue=1e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004706
- InterPro:   IPR002657 [H]

Pfam domain/function: PF01758 SBF [H]

EC number: NA

Molecular weight: Translated: 41880; Mature: 41749

Theoretical pI: Translated: 9.55; Mature: 9.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTQKTRFPPPVQAGGQLNVFERYLTLWVGLCIGVGILLGRIAPGIAVSLNAASIHQVSI
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCHHHHHHH
PIAVCLFFMMYPIMVKIDFSQARRAARTPKPVLLTLGINWLVKPFTMVIFAQFFLGQLFA
HHHHHHHHHHHHHHEEEEHHHHHHHHCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHH
PLLQGTELVRGSDITLANSYIAGAILLGIAPCTAMVLMWGYLSYSNQGHTLVMVAVNSLA
HHHCCCHHCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEHHHHHH
MLFLYAPLGRWLLAANDLDVPWQTIVLSVLIYVGLPLIAGMSSRHWILKHQGQQWFEQVF
HHHHHHHHHHHHEECCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHCCHHHHHHHH
LKRLSPMAVIALLVTLVLLFALKGELIVNNPLHIVLIAVPLFLQTNFIFLITYVIAQKLG
HHHCCHHHHHHHHHHHHHHHHHCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
LTYEDAAPAALIGASNHFEVAIATAVMLFGLNSGAALATVVGVLIEVPVMLALVEVCKRT
CCCCCCCCEEEECCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
AFWFPRDPEKATLLDPRCSRPLA
CCCCCCCCCCCCEECCCCCCCCC
>Mature Secondary Structure 
TTQKTRFPPPVQAGGQLNVFERYLTLWVGLCIGVGILLGRIAPGIAVSLNAASIHQVSI
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCHHHHHHH
PIAVCLFFMMYPIMVKIDFSQARRAARTPKPVLLTLGINWLVKPFTMVIFAQFFLGQLFA
HHHHHHHHHHHHHHEEEEHHHHHHHHCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHH
PLLQGTELVRGSDITLANSYIAGAILLGIAPCTAMVLMWGYLSYSNQGHTLVMVAVNSLA
HHHCCCHHCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEHHHHHH
MLFLYAPLGRWLLAANDLDVPWQTIVLSVLIYVGLPLIAGMSSRHWILKHQGQQWFEQVF
HHHHHHHHHHHHEECCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHCCHHHHHHHH
LKRLSPMAVIALLVTLVLLFALKGELIVNNPLHIVLIAVPLFLQTNFIFLITYVIAQKLG
HHHCCHHHHHHHHHHHHHHHHHCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
LTYEDAAPAALIGASNHFEVAIATAVMLFGLNSGAALATVVGVLIEVPVMLALVEVCKRT
CCCCCCCCEEEECCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
AFWFPRDPEKATLLDPRCSRPLA
CCCCCCCCCCCCEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]