Click here to switch to the map view.

The map label for this gene is arsC [H]

Identifier: 158333786

GI number: 158333786

Start: 581687

End: 582088

Strand: Reverse

Name: arsC [H]

Synonym: AM1_0594

Alternate gene names: 158333786

Gene position: 582088-581687 (Counterclockwise)

Preceding gene: 158333787

Following gene: 158333785

Centisome position: 8.95

GC content: 48.01

Gene sequence:

>402_bases
ATGATGAAACGCATCATGTTTGTTTGTAAGCATAATTCGCGCCGTTCCCACATGGCTGAGGGTTATGCCCGATCAATGGC
AGGAGACAAGCTAGAAGTGGCTAGTGCAGGATTAGACGGAAGTCAAGTCGATCCCCTTACCATTCAAGTGATGCAAGAAG
AAGGCATCGACATTAGCAATCACACCTCTAACGCCTTAACTGAATTTAAGCCAGAGGATTTTGAGGCCGTCATTTCTTTA
TGCGGTTGTGGGGTGAATCTACCAGAGGCGTGGGTAACTCGACCGATATTTGCAGATTGGCAACTAGACGATCCTGCGGG
TCAATCGATTGAAGTCTTTCGCACCATCCGCGATCAGGTCAGGCAGCATGTCAAAACATTAGTCGAGACTGTCAGCCCTT
AG

Upstream 100 bases:

>100_bases
AAGCGCACGGCTTTTTGGTTCCCCAGAGATCCTGAAAAAGCGACGCTTTTAGATCCTCGTTGTTCTCGTCCTTTGGCTTA
ATTCACATTCCTGGGAGTAA

Downstream 100 bases:

>100_bases
GTGAGATTAGTATCCTGACCTAGTCATGGTCTAGAACCCGTCATGACTTAGAAATAGTTATCTAGTCATCTGTAGTTAGG
GCTGCTATTCTACCCATTAC

Product: arsenate reductase

Products: NA

Alternate protein names: Arsenate reductase; Arsenical pump modifier; Low molecular weight protein-tyrosine-phosphatase [H]

Number of amino acids: Translated: 133; Mature: 133

Protein sequence:

>133_residues
MMKRIMFVCKHNSRRSHMAEGYARSMAGDKLEVASAGLDGSQVDPLTIQVMQEEGIDISNHTSNALTEFKPEDFEAVISL
CGCGVNLPEAWVTRPIFADWQLDDPAGQSIEVFRTIRDQVRQHVKTLVETVSP

Sequences:

>Translated_133_residues
MMKRIMFVCKHNSRRSHMAEGYARSMAGDKLEVASAGLDGSQVDPLTIQVMQEEGIDISNHTSNALTEFKPEDFEAVISL
CGCGVNLPEAWVTRPIFADWQLDDPAGQSIEVFRTIRDQVRQHVKTLVETVSP
>Mature_133_residues
MMKRIMFVCKHNSRRSHMAEGYARSMAGDKLEVASAGLDGSQVDPLTIQVMQEEGIDISNHTSNALTEFKPEDFEAVISL
CGCGVNLPEAWVTRPIFADWQLDDPAGQSIEVFRTIRDQVRQHVKTLVETVSP

Specific function: Reduces arsenate [As(V)] to arsenite [As(III)] and dephosphorylates tyrosine phosphorylated proteins, low-MW aryl phosphates and natural and synthetic acyl phosphates. Could switch between different functions in different circumstances [H]

COG id: COG0394

COG function: function code T; Protein-tyrosine-phosphatase

Gene ontology:
GO:0004725: Arsenate reductase
GO:0006470: Arsenate reductase
GO:0016787: Arsenate reductase
GO:0035335: Arsenate reductase

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the low molecular weight phosphotyrosine protein phosphatase superfamily. ArsC family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014064
- InterPro:   IPR017867 [H]

Pfam domain/function: PF01451 LMWPc [H]

EC number: =3.1.3.48 [H]

Molecular weight: Translated: 14834; Mature: 14834

Theoretical pI: Translated: 4.93; Mature: 4.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
6.8 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
6.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMKRIMFVCKHNSRRSHMAEGYARSMAGDKLEVASAGLDGSQVDPLTIQVMQEEGIDISN
CCCHHEEECCCCCCHHHHHHHHHHHHCCCCEEEHHCCCCCCCCCCEEEEEECCCCCCCCC
HTSNALTEFKPEDFEAVISLCGCGVNLPEAWVTRPIFADWQLDDPAGQSIEVFRTIRDQV
CCCCHHHCCCCHHHHHHHHHHCCCCCCCHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHH
RQHVKTLVETVSP
HHHHHHHHHHCCC
>Mature Secondary Structure
MMKRIMFVCKHNSRRSHMAEGYARSMAGDKLEVASAGLDGSQVDPLTIQVMQEEGIDISN
CCCHHEEECCCCCCHHHHHHHHHHHHCCCCEEEHHCCCCCCCCCCEEEEEECCCCCCCCC
HTSNALTEFKPEDFEAVISLCGCGVNLPEAWVTRPIFADWQLDDPAGQSIEVFRTIRDQV
CCCCHHHCCCCHHHHHHHHHHCCCCCCCHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHH
RQHVKTLVETVSP
HHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]