Click here to switch to the map view.

The map label for this gene is pgm [H]

Identifier: 158333314

GI number: 158333314

Start: 89647

End: 91185

Strand: Direct

Name: pgm [H]

Synonym: AM1_0084

Alternate gene names: 158333314

Gene position: 89647-91185 (Clockwise)

Preceding gene: 158333313

Following gene: 158333316

Centisome position: 1.38

GC content: 48.41

Gene sequence:

>1539_bases
ATGACCCTGACCGCATTTAACTGGCCTCAACTTCAGAATGGTTCAGATATTCGAGGCGTTGCATTAGAGGGGGTTGAAGG
GGAAGCCGTAAACCTAACCCCAGAGATCGCCCAGATCCTAGGAATGGCTTTTGTCCATTGGCTCTCCCAAACTCTGAATA
AATCTACTAGTGAACTAACCGTTGGTGTGGGTCGAGATAGCCGCATTTCTGGCCCCACTTTGATGGACGCTGTTCTGGCC
GGAATTACCAAAATGGGGAGTAACGGCTATAACTTTGGGTTAGCCTCCACCCCAGCCATGTTTAAAAGCACGGTTACCGA
TGGCTTTAACTGTGATGGGGCTATTATGCTAACCGCCAGTCATTTGCCCTTTAATCGCAATGGCCTCAAGTTCTTTACCG
CCCAAGGGGGCCTAGGCAAAGGCGATATCACCCAAATCCTCAGTCTGGCTGCTGAGCAGACATTTGAAAAAGCTGCAGAT
CCGGGTCAGGTGTCTGAGCATAACTTTATTGGCGTGTACGCAGCAGAACTCGTCAGCCAGATTCGCGCAGCCGTTAATCA
TCCAGATCAGTTTGAGCAACCCTTGCAAGGGCTCCACATTGTGGTCGATGCTGGCAATGGAGCTGGAGGGTTTTATGCGG
AGCAAGTCTTAAAGCCCCTGGGAGCAGATATAACGGGCAGTCAATTCTTAGACCCAGATGGCACGTTCCCCAACCATATT
CCAAATCCTGAGAACAAAGAAGCAATGGCGGCCATTTGCCAAGCCGTAACAGAACAGCAGGCTGACTTTGGCATTATTTT
CGATACAGATGTTGATCGGGCTGCTGCTGTCGATCATTTGGGTCAAGACCTCAATCGCAATCGGCTAATTGCCTTGATCT
CTGCTGTGGTATTGAGAGAACATCCGGGCTCCACCATTGTTACGGATTCCATTACCTCCGATGGGCTCTCCCAATTTATT
GGAGATGAGTTAGGCGGCGTCCATCATCGGTTTAAGCGGGGCTACAAAAATGTGATCAATGAGTCCGTTCGCTTAAACCA
ATCTGGTCAAGAATCTTGGTTAGCCATTGAGACCTCCGGTCACGGGGCGATGAAGGAGAACTATTTTCTGGATGATGGGG
CTTATTTGATCAGTAAACTGCTTGTCGAACTGGCTAAGTCTAAGATGGCAGGTCGCAACATCACGGACTTGATCGCCAAC
CTCACAGAACCTCAGGAAAGTGAAGAATATCGCATCAAGATCCAGACGGATGATTTTAAAGCCCATGGCAACTCGGTGAT
TTCTAAGTTAGAAGAATTTGCTGGTCAACAAACAGACTGGCAGATCGTTCCCAATAACTATGAAGGGATTCGGATCGCCT
TAAACTCGCCCTCAGAGCAAGGCTGGTTGTTACTGCGATTATCACTCCACGATCCCGTTTTACCTCTAAATATTGAATCC
AATGTAGAGGGAGGTGTGGCCAGTATTTCGGCTAAACTCACTTCCTTTTTCCAAAGTATCGATGGACTGAACTTGCCTCC
AGAGCTTATCAGTTCCTAG

Upstream 100 bases:

>100_bases
CTAAACCTGTTCGTTCTCGACTATTAATCAAAGCTGTATATTTTACGGGGGATCATTTTCTCGGGGCATGATGGGGGTTG
TACTGAACTTGCGATCGCAT

Downstream 100 bases:

>100_bases
AAACTGGCAGCTTCCTAGACCTGGGGGGTAGAAGGGCATTGTTCCGTCTGTACAGCTTCTATTTTTAAAACCGTGATCGG
TGCAGGCAAGCTACCTTCTT

Product: phosphoglucomutase/phosphomannomutase family protein

Products: NA

Alternate protein names: PGM; Glucose phosphomutase [H]

Number of amino acids: Translated: 512; Mature: 511

Protein sequence:

>512_residues
MTLTAFNWPQLQNGSDIRGVALEGVEGEAVNLTPEIAQILGMAFVHWLSQTLNKSTSELTVGVGRDSRISGPTLMDAVLA
GITKMGSNGYNFGLASTPAMFKSTVTDGFNCDGAIMLTASHLPFNRNGLKFFTAQGGLGKGDITQILSLAAEQTFEKAAD
PGQVSEHNFIGVYAAELVSQIRAAVNHPDQFEQPLQGLHIVVDAGNGAGGFYAEQVLKPLGADITGSQFLDPDGTFPNHI
PNPENKEAMAAICQAVTEQQADFGIIFDTDVDRAAAVDHLGQDLNRNRLIALISAVVLREHPGSTIVTDSITSDGLSQFI
GDELGGVHHRFKRGYKNVINESVRLNQSGQESWLAIETSGHGAMKENYFLDDGAYLISKLLVELAKSKMAGRNITDLIAN
LTEPQESEEYRIKIQTDDFKAHGNSVISKLEEFAGQQTDWQIVPNNYEGIRIALNSPSEQGWLLLRLSLHDPVLPLNIES
NVEGGVASISAKLTSFFQSIDGLNLPPELISS

Sequences:

>Translated_512_residues
MTLTAFNWPQLQNGSDIRGVALEGVEGEAVNLTPEIAQILGMAFVHWLSQTLNKSTSELTVGVGRDSRISGPTLMDAVLA
GITKMGSNGYNFGLASTPAMFKSTVTDGFNCDGAIMLTASHLPFNRNGLKFFTAQGGLGKGDITQILSLAAEQTFEKAAD
PGQVSEHNFIGVYAAELVSQIRAAVNHPDQFEQPLQGLHIVVDAGNGAGGFYAEQVLKPLGADITGSQFLDPDGTFPNHI
PNPENKEAMAAICQAVTEQQADFGIIFDTDVDRAAAVDHLGQDLNRNRLIALISAVVLREHPGSTIVTDSITSDGLSQFI
GDELGGVHHRFKRGYKNVINESVRLNQSGQESWLAIETSGHGAMKENYFLDDGAYLISKLLVELAKSKMAGRNITDLIAN
LTEPQESEEYRIKIQTDDFKAHGNSVISKLEEFAGQQTDWQIVPNNYEGIRIALNSPSEQGWLLLRLSLHDPVLPLNIES
NVEGGVASISAKLTSFFQSIDGLNLPPELISS
>Mature_511_residues
TLTAFNWPQLQNGSDIRGVALEGVEGEAVNLTPEIAQILGMAFVHWLSQTLNKSTSELTVGVGRDSRISGPTLMDAVLAG
ITKMGSNGYNFGLASTPAMFKSTVTDGFNCDGAIMLTASHLPFNRNGLKFFTAQGGLGKGDITQILSLAAEQTFEKAADP
GQVSEHNFIGVYAAELVSQIRAAVNHPDQFEQPLQGLHIVVDAGNGAGGFYAEQVLKPLGADITGSQFLDPDGTFPNHIP
NPENKEAMAAICQAVTEQQADFGIIFDTDVDRAAAVDHLGQDLNRNRLIALISAVVLREHPGSTIVTDSITSDGLSQFIG
DELGGVHHRFKRGYKNVINESVRLNQSGQESWLAIETSGHGAMKENYFLDDGAYLISKLLVELAKSKMAGRNITDLIANL
TEPQESEEYRIKIQTDDFKAHGNSVISKLEEFAGQQTDWQIVPNNYEGIRIALNSPSEQGWLLLRLSLHDPVLPLNIESN
VEGGVASISAKLTSFFQSIDGLNLPPELISS

Specific function: This enzyme participates in both the breakdown and synthesis of glucose [H]

COG id: COG1109

COG function: function code G; Phosphomannomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphohexose mutase family [H]

Homologues:

Organism=Escherichia coli, GI1788361, Length=487, Percent_Identity=26.4887063655031, Blast_Score=106, Evalue=5e-24,
Organism=Escherichia coli, GI1789566, Length=476, Percent_Identity=24.5798319327731, Blast_Score=88, Evalue=1e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005844
- InterPro:   IPR016055
- InterPro:   IPR005845
- InterPro:   IPR005846
- InterPro:   IPR005843
- InterPro:   IPR016066
- InterPro:   IPR005841 [H]

Pfam domain/function: PF02878 PGM_PMM_I; PF02879 PGM_PMM_II; PF02880 PGM_PMM_III; PF00408 PGM_PMM_IV [H]

EC number: =5.4.2.2 [H]

Molecular weight: Translated: 55202; Mature: 55070

Theoretical pI: Translated: 4.54; Mature: 4.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLTAFNWPQLQNGSDIRGVALEGVEGEAVNLTPEIAQILGMAFVHWLSQTLNKSTSELT
CEEECCCCCCCCCCCCCCEEEEECCCCCEEECCHHHHHHHHHHHHHHHHHHHCCCCCEEE
VGVGRDSRISGPTLMDAVLAGITKMGSNGYNFGLASTPAMFKSTVTDGFNCDGAIMLTAS
EECCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHCCCCCCCCEEEEEEE
HLPFNRNGLKFFTAQGGLGKGDITQILSLAAEQTFEKAADPGQVSEHNFIGVYAAELVSQ
CCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHH
IRAAVNHPDQFEQPLQGLHIVVDAGNGAGGFYAEQVLKPLGADITGSQFLDPDGTFPNHI
HHHHHCCCHHHHHHHCCEEEEEECCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCC
PNPENKEAMAAICQAVTEQQADFGIIFDTDVDRAAAVDHLGQDLNRNRLIALISAVVLRE
CCCCCHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHC
HPGSTIVTDSITSDGLSQFIGDELGGVHHRFKRGYKNVINESVRLNQSGQESWLAIETSG
CCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECC
HGAMKENYFLDDGAYLISKLLVELAKSKMAGRNITDLIANLTEPQESEEYRIKIQTDDFK
CCCCCCCEEECCHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCEEEEEECCCCH
AHGNSVISKLEEFAGQQTDWQIVPNNYEGIRIALNSPSEQGWLLLRLSLHDPVLPLNIES
HHHHHHHHHHHHHCCCCCCEEECCCCCCCEEEEECCCCCCCEEEEEEECCCCEEEEEECC
NVEGGVASISAKLTSFFQSIDGLNLPPELISS
CCCCCHHHHHHHHHHHHHHHCCCCCCHHHHCC
>Mature Secondary Structure 
TLTAFNWPQLQNGSDIRGVALEGVEGEAVNLTPEIAQILGMAFVHWLSQTLNKSTSELT
EEECCCCCCCCCCCCCCEEEEECCCCCEEECCHHHHHHHHHHHHHHHHHHHCCCCCEEE
VGVGRDSRISGPTLMDAVLAGITKMGSNGYNFGLASTPAMFKSTVTDGFNCDGAIMLTAS
EECCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHCCCCCCCCEEEEEEE
HLPFNRNGLKFFTAQGGLGKGDITQILSLAAEQTFEKAADPGQVSEHNFIGVYAAELVSQ
CCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHH
IRAAVNHPDQFEQPLQGLHIVVDAGNGAGGFYAEQVLKPLGADITGSQFLDPDGTFPNHI
HHHHHCCCHHHHHHHCCEEEEEECCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCC
PNPENKEAMAAICQAVTEQQADFGIIFDTDVDRAAAVDHLGQDLNRNRLIALISAVVLRE
CCCCCHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHC
HPGSTIVTDSITSDGLSQFIGDELGGVHHRFKRGYKNVINESVRLNQSGQESWLAIETSG
CCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECC
HGAMKENYFLDDGAYLISKLLVELAKSKMAGRNITDLIANLTEPQESEEYRIKIQTDDFK
CCCCCCCEEECCHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCEEEEEECCCCH
AHGNSVISKLEEFAGQQTDWQIVPNNYEGIRIALNSPSEQGWLLLRLSLHDPVLPLNIES
HHHHHHHHHHHHHCCCCCCEEECCCCCCCEEEEECCCCCCCEEEEEEECCCCEEEEEECC
NVEGGVASISAKLTSFFQSIDGLNLPPELISS
CCCCCHHHHHHHHHHHHHHHCCCCCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8157643; 8188595 [H]