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The map label for this gene is aes [C]

Identifier: 158333316

GI number: 158333316

Start: 92204

End: 93379

Strand: Direct

Name: aes [C]

Synonym: AM1_0086

Alternate gene names: 158333316

Gene position: 92204-93379 (Clockwise)

Preceding gene: 158333314

Following gene: 158333318

Centisome position: 1.42

GC content: 47.11

Gene sequence:

>1176_bases
ATGTTCTATCGATTGTTACAACTTCTCATTGGGATCGGGCTATTTCTCAGTCTCTGGATAGTCGTTCCAGCTCCCACATT
TTCGTTACTTCCCCTGGGAGTTGGAGCCCCTGAAATTAGTCCAGCGTTAATGGTACTAAATGCGATAGCACTCTTGCTCA
CGCTGTTTTACCACAGCCGCAAGACCGCCTTTCGGATCATGATGGTAGGAGGCCTGTTGGGATTAGTGTTGAGTAGCTTG
CCCCTGATTCAACTTCCTAGGGCCATTCAACAAGCGAATGGGGCAATGCAAACCAACCTAGGCAAAGATTATTTAGCTAA
ATTATCGCCAGCCCAGCAAGCCCAACTCCGCCCCCATCCTTTTAGTCTTCTCGACTTTATTCGCCAAATCCCCCTGGGAG
ATATCCGTCAAGATTTGGGGATTCCCTTTGCTCAGCCCGATGGACAGACCCTAAAACTCAATCTTTACCGCCCTCCCCAG
CCAGGGCTCTATCCAGGCATTGTTGTGATTTACGGAGGGGCATGGCGGACAGGGAGCCCTAACAGCAACAGCCAATTCAG
TCAGTATCTCGCAGCTCGGGGTTACGTCGTTTGGGCCATTTCCTATCGACATGCCCCCCACTACAAATTTCCTGCTCAAC
TGGAAGATGTGCAAACAGCTCTCACTTTTATCAAAGATCACGCATTGGATTACGAGACAGATCCAAATCGAGTGGCATTA
TTGGGGCGCTCTGCTGGGGGTCACCTGGCAACATTGGCTGCTTTTAAGAACAGCGATCTTCCTATTCGAGCAGTAGTTAG
TTATTACAGTCCTGTCGAATTAGCAAAAAGCTATTATGATCCCCCTTTCCCGGACCCTATTGATGTCAAATCAGTGTTGA
GGTCGTTCATTGGAGGTGATCCCAAACAATTTCCTGAGAAATACAGACAAGCCTCACCTATTCATGCCGTCAAGCCCAAT
CTTCCTCCTACTTTGCTAGTTTATGGAGCGCAAGATCATCTTGTAGAAGTAAAATATGGTCGAAAAATGCTCAAAAAACT
TCAATCCGAGAAAAATATAGTTGTCATGCTTGACATTCCATGGGCAGAGCACGCATTTGATGCAGTTTTTAGTGGTGTTA
GCAACCAGTTTGCCCTCTACTATACGGAACGTTTTTTAGCTTGGGCGCTACTCTAA

Upstream 100 bases:

>100_bases
TCGATTTATCTCTCCATGCTAAATCACCCTAAGATCATTGAACCGATCCCCTTTGGGCATTTTGCCTCATTTCACTTTTA
ACCTCATTTCAGAGACAACT

Downstream 100 bases:

>100_bases
CAGTTATTGGCATTATCAGCACTTACAATCAATTAGTGCATAGCCAAGAACAAAGTTTGGATTGGATTGTAATCAGTTCA
ATCCATTAAATGGCAGCGAA

Product: esterase/lipase/thioesterase

Products: alcohol; a carboxylate [C]

Alternate protein names: Alpha/Beta Hydrolase Fold-3 Domain Protein; Lipase/Esterase; Esterase; Lipase; Esterase/Lipase; Esterase/Lipase-Like Protein; Esterase/Lipase/Thioesterase; Alpha/Beta Hydrolase Fold-3 Domain-Containing Protein; Alpha/Beta Hydrolase Fold Domain Protein; Alpha/Beta Hydrolase; Esterase/Lipase/Thioesterase Family Protein; Carboxylesterase Family Protein; Hydrolase; Alpha/Beta Hydrolase Fold Protein-3 Domain Protein; Peptidase S9 Prolyl Oligopeptidase; Carboxylesterase; Esterase LipC; Esterase LipO; Pectinesterase; Esterase/Lipase-Like; Dienelactone Hydrolase; Peptidase; Peptidase S; Lipoprotein; Membrane-Bound Esterase LipM; Acetyl Esterase; Alpha/Beta Hydrolase Fold; Alpha/Beta Hydrolase Fold Protein; Membrane-Anchored Peptidase; Alpha/Beta Hydrolase Fold Family Protein; Carboxylesterase Type B; Coagulation Factor 5/8 Type Domain Protein; Lipase/Esterase Protein; Carboxylesterase LipQ; Alpha/Beta Fold Family Hydrolase; Alpha/Beta Hydrolase Family Protein; Lipase LipA; Peptidase S9A/B/C Families; Para-Nitrobenzyl Esterase; Esterase LipM

Number of amino acids: Translated: 391; Mature: 391

Protein sequence:

>391_residues
MFYRLLQLLIGIGLFLSLWIVVPAPTFSLLPLGVGAPEISPALMVLNAIALLLTLFYHSRKTAFRIMMVGGLLGLVLSSL
PLIQLPRAIQQANGAMQTNLGKDYLAKLSPAQQAQLRPHPFSLLDFIRQIPLGDIRQDLGIPFAQPDGQTLKLNLYRPPQ
PGLYPGIVVIYGGAWRTGSPNSNSQFSQYLAARGYVVWAISYRHAPHYKFPAQLEDVQTALTFIKDHALDYETDPNRVAL
LGRSAGGHLATLAAFKNSDLPIRAVVSYYSPVELAKSYYDPPFPDPIDVKSVLRSFIGGDPKQFPEKYRQASPIHAVKPN
LPPTLLVYGAQDHLVEVKYGRKMLKKLQSEKNIVVMLDIPWAEHAFDAVFSGVSNQFALYYTERFLAWALL

Sequences:

>Translated_391_residues
MFYRLLQLLIGIGLFLSLWIVVPAPTFSLLPLGVGAPEISPALMVLNAIALLLTLFYHSRKTAFRIMMVGGLLGLVLSSL
PLIQLPRAIQQANGAMQTNLGKDYLAKLSPAQQAQLRPHPFSLLDFIRQIPLGDIRQDLGIPFAQPDGQTLKLNLYRPPQ
PGLYPGIVVIYGGAWRTGSPNSNSQFSQYLAARGYVVWAISYRHAPHYKFPAQLEDVQTALTFIKDHALDYETDPNRVAL
LGRSAGGHLATLAAFKNSDLPIRAVVSYYSPVELAKSYYDPPFPDPIDVKSVLRSFIGGDPKQFPEKYRQASPIHAVKPN
LPPTLLVYGAQDHLVEVKYGRKMLKKLQSEKNIVVMLDIPWAEHAFDAVFSGVSNQFALYYTERFLAWALL
>Mature_391_residues
MFYRLLQLLIGIGLFLSLWIVVPAPTFSLLPLGVGAPEISPALMVLNAIALLLTLFYHSRKTAFRIMMVGGLLGLVLSSL
PLIQLPRAIQQANGAMQTNLGKDYLAKLSPAQQAQLRPHPFSLLDFIRQIPLGDIRQDLGIPFAQPDGQTLKLNLYRPPQ
PGLYPGIVVIYGGAWRTGSPNSNSQFSQYLAARGYVVWAISYRHAPHYKFPAQLEDVQTALTFIKDHALDYETDPNRVAL
LGRSAGGHLATLAAFKNSDLPIRAVVSYYSPVELAKSYYDPPFPDPIDVKSVLRSFIGGDPKQFPEKYRQASPIHAVKPN
LPPTLLVYGAQDHLVEVKYGRKMLKKLQSEKNIVVMLDIPWAEHAFDAVFSGVSNQFALYYTERFLAWALL

Specific function: Has An Esterase Activity. Triacetyl Glycerol (Triacetin) Is A Substrate Of The Enzyme. [C]

COG id: COG0657

COG function: function code I; Esterase/lipase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 3.1.1.- [C]

Molecular weight: Translated: 43481; Mature: 43481

Theoretical pI: Translated: 9.79; Mature: 9.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFYRLLQLLIGIGLFLSLWIVVPAPTFSLLPLGVGAPEISPALMVLNAIALLLTLFYHSR
CHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHH
KTAFRIMMVGGLLGLVLSSLPLIQLPRAIQQANGAMQTNLGKDYLAKLSPAQQAQLRPHP
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHCCCHHHHHHCCCHHHCCCCCCC
FSLLDFIRQIPLGDIRQDLGIPFAQPDGQTLKLNLYRPPQPGLYPGIVVIYGGAWRTGSP
HHHHHHHHHCCCHHHHHHHCCCCCCCCCCEEEEEEECCCCCCCCCCEEEEECCCCCCCCC
NSNSQFSQYLAARGYVVWAISYRHAPHYKFPAQLEDVQTALTFIKDHALDYETDPNRVAL
CCCHHHHHHHHHCCEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCEEEE
LGRSAGGHLATLAAFKNSDLPIRAVVSYYSPVELAKSYYDPPFPDPIDVKSVLRSFIGGD
EECCCCCCEEEEEHHCCCCCCHHHHHHHCCHHHHHHHHCCCCCCCCCCHHHHHHHHHCCC
PKQFPEKYRQASPIHAVKPNLPPTLLVYGAQDHLVEVKYGRKMLKKLQSEKNIVVMLDIP
HHHHHHHHHHCCCCCEECCCCCCEEEEECCCCCEEEEHHHHHHHHHHHCCCCEEEEEECC
WAEHAFDAVFSGVSNQFALYYTERFLAWALL
CHHHHHHHHHHCCCCCEEEEHHHHHHHHHCC
>Mature Secondary Structure
MFYRLLQLLIGIGLFLSLWIVVPAPTFSLLPLGVGAPEISPALMVLNAIALLLTLFYHSR
CHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHH
KTAFRIMMVGGLLGLVLSSLPLIQLPRAIQQANGAMQTNLGKDYLAKLSPAQQAQLRPHP
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHCCCHHHHHHCCCHHHCCCCCCC
FSLLDFIRQIPLGDIRQDLGIPFAQPDGQTLKLNLYRPPQPGLYPGIVVIYGGAWRTGSP
HHHHHHHHHCCCHHHHHHHCCCCCCCCCCEEEEEEECCCCCCCCCCEEEEECCCCCCCCC
NSNSQFSQYLAARGYVVWAISYRHAPHYKFPAQLEDVQTALTFIKDHALDYETDPNRVAL
CCCHHHHHHHHHCCEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCEEEE
LGRSAGGHLATLAAFKNSDLPIRAVVSYYSPVELAKSYYDPPFPDPIDVKSVLRSFIGGD
EECCCCCCEEEEEHHCCCCCCHHHHHHHCCHHHHHHHHCCCCCCCCCCHHHHHHHHHCCC
PKQFPEKYRQASPIHAVKPNLPPTLLVYGAQDHLVEVKYGRKMLKKLQSEKNIVVMLDIP
HHHHHHHHHHCCCCCEECCCCCCEEEEECCCCCEEEEHHHHHHHHHHHCCCCEEEEEECC
WAEHAFDAVFSGVSNQFALYYTERFLAWALL
CHHHHHHHHHHCCCCCEEEEHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Carboxylic ester; H2O [C]

Specific reaction: Carboxylic ester + H2O = an alcohol + carboxylate [C]

General reaction: Hydrolase; Acting on ester bonds; Carboxylic ester hydrolases [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA