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The map label for this gene is trxB [H]

Identifier: 158319045

GI number: 158319045

Start: 8963979

End: 8965025

Strand: Direct

Name: trxB [H]

Synonym: Franean1_7328

Alternate gene names: 158319045

Gene position: 8963979-8965025 (Clockwise)

Preceding gene: 158319044

Following gene: 158319046

Centisome position: 99.8

GC content: 71.35

Gene sequence:

>1047_bases
GTGACAGCCCAGGGCAAGGACCAGGCCGGTCAGGCCGCCGGAGCGGAGCGTTCCGGCGAGCGCGTCCTGGACGTCGTCAT
CATCGGGTCGGGGCCGGCCGGCTACACCGCGGCGATCTACACCGCCCGGGCGAACCTGAAGCCGGTCGTCTTCGAGGGCG
CGGTATCCGCGGGCGGCGCGCTGATGACCACGACCGAGGTGGAGAACTTCCCGGGCTTCCCCGAGGGCATCCAGGGGCCG
GAGCTCATGGAGAACCTGCGCGCCCAGGCGGAGCGGTTCGGCGCCGAGCTCATCGCGGACGACGTCACCGAAGTCGACCT
GGCCGCGGATCCGAAGGTGGTCAAGGTGGGCGACGAGACCTACCTGGCCCGCTCGGTCATCGTCGCGACCGGCTCGGCCT
ACAAGAAGCTCGGCGTCGAGCACGAGGACCGGCTGCTCGGCCGGGGCGTGTCGGCCTGCGCGACCTGTGACGGCTTCTTC
TTCCGGGACCAGGACATCGCGGTCGTCGGCGGCGGCGACTCGGCGCTGGAGGAGGCGACCTTCCTCACCCGGTTCGCGAA
GTCGGTGACGATCGTGCACCGGCGCGACAGGCTGCGCGCCAGCGCGATCATGCAGGAGCGGGCGTTCGCCAACCCGAAGG
TCCGGTTCCGGTGGAACGCCGTGGTCGAGGAGGTCCTCGGCGAGGACAAGGTCACCGGCGTCCGGCTGCGTGACACGGTC
ACCGACAAGACGGACGAGCTGGCGATCACCGGCCTGTTCGTGGCGATCGGCCACCTCCCCCGCACGGATCTGATCCACGA
CCAGCTCGAGCTGGACGGCGAGGGCTACATCAAGGTGACGCACCCGACCACCCAGACCAACATCGCGGGTGTGTTCGCCT
GCGGTGACGTCGTCGACCACACCTACCGCCAGGCGATCACCGCGGCCGGCACCGGGTGCTCCGCCGCCCTCGACGCCGAG
CGCTACATCGCCGGCCTGGAGGGCGCCGCTGACAGCGCCGCCGAGGCGCCCCGGGTACCGGCACCGGAGCTCGCCGCGAC
GACCTGA

Upstream 100 bases:

>100_bases
CCGCGGTCCGCGACGGTTATGGGGGCAGACATCACGTCGGCGGGGCCAACGATCGACAGAATCGGCGAAGCCTCGTACGA
CAGTCGTGAAGGGAGTGGGT

Downstream 100 bases:

>100_bases
CGCGGACCAACCTGTGCTGTGGCGGGAGCCCCGCCACAGCACAGCCGTCAGCCACCAGTCCAAAGACACAAGAGCGCAAA
CCCTGAGGAGAACGCCATGG

Product: thioredoxin reductase

Products: NA

Alternate protein names: TRXR [H]

Number of amino acids: Translated: 348; Mature: 347

Protein sequence:

>348_residues
MTAQGKDQAGQAAGAERSGERVLDVVIIGSGPAGYTAAIYTARANLKPVVFEGAVSAGGALMTTTEVENFPGFPEGIQGP
ELMENLRAQAERFGAELIADDVTEVDLAADPKVVKVGDETYLARSVIVATGSAYKKLGVEHEDRLLGRGVSACATCDGFF
FRDQDIAVVGGGDSALEEATFLTRFAKSVTIVHRRDRLRASAIMQERAFANPKVRFRWNAVVEEVLGEDKVTGVRLRDTV
TDKTDELAITGLFVAIGHLPRTDLIHDQLELDGEGYIKVTHPTTQTNIAGVFACGDVVDHTYRQAITAAGTGCSAALDAE
RYIAGLEGAADSAAEAPRVPAPELAATT

Sequences:

>Translated_348_residues
MTAQGKDQAGQAAGAERSGERVLDVVIIGSGPAGYTAAIYTARANLKPVVFEGAVSAGGALMTTTEVENFPGFPEGIQGP
ELMENLRAQAERFGAELIADDVTEVDLAADPKVVKVGDETYLARSVIVATGSAYKKLGVEHEDRLLGRGVSACATCDGFF
FRDQDIAVVGGGDSALEEATFLTRFAKSVTIVHRRDRLRASAIMQERAFANPKVRFRWNAVVEEVLGEDKVTGVRLRDTV
TDKTDELAITGLFVAIGHLPRTDLIHDQLELDGEGYIKVTHPTTQTNIAGVFACGDVVDHTYRQAITAAGTGCSAALDAE
RYIAGLEGAADSAAEAPRVPAPELAATT
>Mature_347_residues
TAQGKDQAGQAAGAERSGERVLDVVIIGSGPAGYTAAIYTARANLKPVVFEGAVSAGGALMTTTEVENFPGFPEGIQGPE
LMENLRAQAERFGAELIADDVTEVDLAADPKVVKVGDETYLARSVIVATGSAYKKLGVEHEDRLLGRGVSACATCDGFFF
RDQDIAVVGGGDSALEEATFLTRFAKSVTIVHRRDRLRASAIMQERAFANPKVRFRWNAVVEEVLGEDKVTGVRLRDTVT
DKTDELAITGLFVAIGHLPRTDLIHDQLELDGEGYIKVTHPTTQTNIAGVFACGDVVDHTYRQAITAAGTGCSAALDAER
YIAGLEGAADSAAEAPRVPAPELAATT

Specific function: Component of the thioredoxin-thioredoxin reductase system which may be involved in biosynthesis of penicillins and cephalosporins and may be important in determining the thiol- disulfide redox balance [H]

COG id: COG0492

COG function: function code O; Thioredoxin reductase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI1787114, Length=311, Percent_Identity=51.7684887459807, Blast_Score=303, Evalue=1e-83,
Organism=Escherichia coli, GI87081763, Length=331, Percent_Identity=32.02416918429, Blast_Score=140, Evalue=1e-34,
Organism=Saccharomyces cerevisiae, GI6320560, Length=314, Percent_Identity=46.4968152866242, Blast_Score=291, Evalue=1e-79,
Organism=Saccharomyces cerevisiae, GI6321898, Length=314, Percent_Identity=45.859872611465, Blast_Score=283, Evalue=3e-77,

Paralogues:

None

Copy number: 808 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR008255
- InterPro:   IPR001327
- InterPro:   IPR000103
- InterPro:   IPR005982 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: =1.8.1.9 [H]

Molecular weight: Translated: 36795; Mature: 36663

Theoretical pI: Translated: 4.57; Mature: 4.57

Prosite motif: PS00573 PYRIDINE_REDOX_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAQGKDQAGQAAGAERSGERVLDVVIIGSGPAGYTAAIYTARANLKPVVFEGAVSAGGA
CCCCCCCCCCCCCCCCCCCCEEEEEEEECCCCCCCEEEEEEECCCCCEEEEECCCCCCCE
LMTTTEVENFPGFPEGIQGPELMENLRAQAERFGAELIADDVTEVDLAADPKVVKVGDET
EEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCEEEECCCH
YLARSVIVATGSAYKKLGVEHEDRLLGRGVSACATCDGFFFRDQDIAVVGGGDSALEEAT
HHHHEEEEECCCHHHHHCCCHHHHHHHCCCHHHHHCCCCEEECCCEEEECCCCHHHHHHH
FLTRFAKSVTIVHRRDRLRASAIMQERAFANPKVRFRWNAVVEEVLGEDKVTGVRLRDTV
HHHHHHHHHHEEHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHCCCCCCCEEEECCC
TDKTDELAITGLFVAIGHLPRTDLIHDQLELDGEGYIKVTHPTTQTNIAGVFACGDVVDH
CCCCCCCHHHHHHHHHCCCCCHHHHHHHHEECCCCEEEEECCCCCCCCEEEEEHHHHHHH
TYRQAITAAGTGCSAALDAERYIAGLEGAADSAAEAPRVPAPELAATT
HHHHHHHHCCCCCCHHHCHHHHHHHCCCCCCCHHCCCCCCCCCCCCCC
>Mature Secondary Structure 
TAQGKDQAGQAAGAERSGERVLDVVIIGSGPAGYTAAIYTARANLKPVVFEGAVSAGGA
CCCCCCCCCCCCCCCCCCCEEEEEEEECCCCCCCEEEEEEECCCCCEEEEECCCCCCCE
LMTTTEVENFPGFPEGIQGPELMENLRAQAERFGAELIADDVTEVDLAADPKVVKVGDET
EEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCEEEECCCH
YLARSVIVATGSAYKKLGVEHEDRLLGRGVSACATCDGFFFRDQDIAVVGGGDSALEEAT
HHHHEEEEECCCHHHHHCCCHHHHHHHCCCHHHHHCCCCEEECCCEEEECCCCHHHHHHH
FLTRFAKSVTIVHRRDRLRASAIMQERAFANPKVRFRWNAVVEEVLGEDKVTGVRLRDTV
HHHHHHHHHHEEHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHCCCCCCCEEEECCC
TDKTDELAITGLFVAIGHLPRTDLIHDQLELDGEGYIKVTHPTTQTNIAGVFACGDVVDH
CCCCCCCHHHHHHHHHCCCCCHHHHHHHHEECCCCEEEEECCCCCCCCEEEEEHHHHHHH
TYRQAITAAGTGCSAALDAERYIAGLEGAADSAAEAPRVPAPELAATT
HHHHHHHHCCCCCCHHHCHHHHHHHCCCCCCCHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8349555; 8423136 [H]