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The map label for this gene is pkn1 [H]

Identifier: 158319018

GI number: 158319018

Start: 8922425

End: 8923945

Strand: Direct

Name: pkn1 [H]

Synonym: Franean1_7301

Alternate gene names: 158319018

Gene position: 8922425-8923945 (Clockwise)

Preceding gene: 158319017

Following gene: 158319019

Centisome position: 99.34

GC content: 74.42

Gene sequence:

>1521_bases
GTGCGTTCCGGTGCCTTGACCGGCGACCCGACCACCACCCGTGACCCTGCCGGCCCGACGGCCGCTCCTGCCCTCGACGC
GGAGGCGCTGGCGGCGGGGCTGGCGGCGGCCCGGGACCGGTCGCTCGCCTACACCGACCTCACCGAGGACGACCTCCTGC
GCCAGCACTCGCCACTAATGTCACCGCTGGTCTGGGATCTCGCGCACATCGGCAACTACGAGGAGATCTGGCTGCTGCGC
GCCCTGACCGGCGCGGCCGAGCTGCGCCCCGGCCTGGACGACGTCTACGACGCCTTCCGGCACAGCCGGGCCAGCCGGAC
CGCGCTGCCGCTGCTCGGCCCGGACGAGGCCCGCGCGTACCTGCGGGACGTCCGCGGGCGGGCGATGGACGTCCTGACCG
GGCTGGACCCCGACCTGCTGCACGCCCCGGAGACGGCCGGCGAGGCCGCCGGACCCGAGGCCGGGAACGGGAACGAGAAC
GGGGCCGCGAGCAGGAACGGGGCCGCGAACGGGAACGGTGAGCGGGACGGCGGCGCGGCCGTCCACCGGCGTGCCCGGCT
GCTGTCGGGGTCGTTCGTCTACGGCATGGTGATCCAGCACGAGCACCAGCACGACGAGACGATGCTCGCGACGCTGCAGC
TGCGCGCGGGCCCGCCCGTCCTGGCCGACCCGCGGGCGGCGCCGCCATCCCCGGCCGGGCCGGTGGACGAGGCGGCCGAG
GTCCTGGTGCCGGCCGGCGAGTTCACCATGGGCACGTCGACCGAGCCGTGGGCGTACGACAACGAGCGGCCGGCGCACCG
GGTGTTCCTGCCCGCCTTCCGCCTCGGCCGCTACCCGGTCACCAACCGGGCCCACCTGGCGTTCATCGCGGACGGCGGCT
ACGCCGACGAGCGGCTCTGGTCCGCCGAGGGCTGGGCGTGGCGCTGCCAGGAGGGCCTGACGGCGCCGCTTTTCTGGTCA
CGCGACGGCGACGTCTGGACACGCCGCCGATTCGGGCGGGTCGAACCGGTGCCTCTCGACGAGCCCGTGCAGCACGTGTG
CTGGTATGAAGCCGAGGCCCACGCCCGCTGGGCCGGACGACGGCTGCCCACGGAGGCCGAGTGGGAGAAGGCGTGTGCGC
ACGACCCCGTCACCGGGCGTTCACGACGGTATCCATGGGGCGACACCGACCCGACTCCCGAGCTTGCGAACCTGGGGCAC
CGCACTGCGCGGCCCGCACCGGTGGGCGGCAGGCCGGCCGGCGCGAGCCCGTACGGCGCCGAACAGATGATCGGGGACGT
CTGGGAATGGACCGGCGGCGGGTTCACCCCTTATCCGGGCTTCGCGTCGTTCCCGTACCGGGAGTACAGCGAGGTCTTCT
ATCCTCGCGATGCGGCCCCGGCCCGGTTCCGGGTGCTGCGCGGCGGCTCCTGGGCGACCGATCCCAGCGCCGTCCGCTCC
ACGTTCCGCAACTGGGACTTTCCGATCCGACGGCAGATCTTCGCCGGGTTCCGGCTCGCCCGCGACGCCGACACCCCCTG
A

Upstream 100 bases:

>100_bases
CCAACCGTTACACGCGGCGGGGGCGCTCCCCGGCCGACGACCTGAACGCGCGTTTCGAGGCGCGCGGGCCGGCTGAGCTG
CTGCGCGAGGAGGCGTCCCA

Downstream 100 bases:

>100_bases
CCCCGCCGCTCCAAGCCCGCACCCGCGCCCGCACCCGAACCCGAACCCGAACCCGCCCGTACCGGTGTACCGGCGTCCCC
ACCTGTGCCCGTGGCCTGGC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 506; Mature: 506

Protein sequence:

>506_residues
MRSGALTGDPTTTRDPAGPTAAPALDAEALAAGLAAARDRSLAYTDLTEDDLLRQHSPLMSPLVWDLAHIGNYEEIWLLR
ALTGAAELRPGLDDVYDAFRHSRASRTALPLLGPDEARAYLRDVRGRAMDVLTGLDPDLLHAPETAGEAAGPEAGNGNEN
GAASRNGAANGNGERDGGAAVHRRARLLSGSFVYGMVIQHEHQHDETMLATLQLRAGPPVLADPRAAPPSPAGPVDEAAE
VLVPAGEFTMGTSTEPWAYDNERPAHRVFLPAFRLGRYPVTNRAHLAFIADGGYADERLWSAEGWAWRCQEGLTAPLFWS
RDGDVWTRRRFGRVEPVPLDEPVQHVCWYEAEAHARWAGRRLPTEAEWEKACAHDPVTGRSRRYPWGDTDPTPELANLGH
RTARPAPVGGRPAGASPYGAEQMIGDVWEWTGGGFTPYPGFASFPYREYSEVFYPRDAAPARFRVLRGGSWATDPSAVRS
TFRNWDFPIRRQIFAGFRLARDADTP

Sequences:

>Translated_506_residues
MRSGALTGDPTTTRDPAGPTAAPALDAEALAAGLAAARDRSLAYTDLTEDDLLRQHSPLMSPLVWDLAHIGNYEEIWLLR
ALTGAAELRPGLDDVYDAFRHSRASRTALPLLGPDEARAYLRDVRGRAMDVLTGLDPDLLHAPETAGEAAGPEAGNGNEN
GAASRNGAANGNGERDGGAAVHRRARLLSGSFVYGMVIQHEHQHDETMLATLQLRAGPPVLADPRAAPPSPAGPVDEAAE
VLVPAGEFTMGTSTEPWAYDNERPAHRVFLPAFRLGRYPVTNRAHLAFIADGGYADERLWSAEGWAWRCQEGLTAPLFWS
RDGDVWTRRRFGRVEPVPLDEPVQHVCWYEAEAHARWAGRRLPTEAEWEKACAHDPVTGRSRRYPWGDTDPTPELANLGH
RTARPAPVGGRPAGASPYGAEQMIGDVWEWTGGGFTPYPGFASFPYREYSEVFYPRDAAPARFRVLRGGSWATDPSAVRS
TFRNWDFPIRRQIFAGFRLARDADTP
>Mature_506_residues
MRSGALTGDPTTTRDPAGPTAAPALDAEALAAGLAAARDRSLAYTDLTEDDLLRQHSPLMSPLVWDLAHIGNYEEIWLLR
ALTGAAELRPGLDDVYDAFRHSRASRTALPLLGPDEARAYLRDVRGRAMDVLTGLDPDLLHAPETAGEAAGPEAGNGNEN
GAASRNGAANGNGERDGGAAVHRRARLLSGSFVYGMVIQHEHQHDETMLATLQLRAGPPVLADPRAAPPSPAGPVDEAAE
VLVPAGEFTMGTSTEPWAYDNERPAHRVFLPAFRLGRYPVTNRAHLAFIADGGYADERLWSAEGWAWRCQEGLTAPLFWS
RDGDVWTRRRFGRVEPVPLDEPVQHVCWYEAEAHARWAGRRLPTEAEWEKACAHDPVTGRSRRYPWGDTDPTPELANLGH
RTARPAPVGGRPAGASPYGAEQMIGDVWEWTGGGFTPYPGFASFPYREYSEVFYPRDAAPARFRVLRGGSWATDPSAVRS
TFRNWDFPIRRQIFAGFRLARDADTP

Specific function: Together with the serine/threonine kinase pknD, may play a role in the specific interactions with host proteins during intracellular growth [H]

COG id: COG1262

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 protein kinase domain [H]

Homologues:

Organism=Homo sapiens, GI257470975, Length=281, Percent_Identity=31.3167259786477, Blast_Score=95, Evalue=1e-19,
Organism=Homo sapiens, GI38202250, Length=289, Percent_Identity=30.4498269896194, Blast_Score=92, Evalue=1e-18,
Organism=Homo sapiens, GI257470977, Length=215, Percent_Identity=33.0232558139535, Blast_Score=83, Evalue=7e-16,
Organism=Homo sapiens, GI194248087, Length=294, Percent_Identity=29.9319727891156, Blast_Score=81, Evalue=3e-15,
Organism=Homo sapiens, GI194248088, Length=299, Percent_Identity=30.1003344481605, Blast_Score=79, Evalue=1e-14,
Organism=Homo sapiens, GI226437577, Length=183, Percent_Identity=35.5191256830601, Blast_Score=66, Evalue=9e-11,
Organism=Drosophila melanogaster, GI20130397, Length=222, Percent_Identity=29.2792792792793, Blast_Score=75, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016187
- InterPro:   IPR011009
- InterPro:   IPR000719
- InterPro:   IPR017442
- InterPro:   IPR005532 [H]

Pfam domain/function: PF03781 DUF323; PF00069 Pkinase [H]

EC number: =2.7.11.1 [H]

Molecular weight: Translated: 55349; Mature: 55349

Theoretical pI: Translated: 5.62; Mature: 5.62

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRSGALTGDPTTTRDPAGPTAAPALDAEALAAGLAAARDRSLAYTDLTEDDLLRQHSPLM
CCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCEEECCCCHHHHHHHHCHHH
SPLVWDLAHIGNYEEIWLLRALTGAAELRPGLDDVYDAFRHSRASRTALPLLGPDEARAY
HHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHH
LRDVRGRAMDVLTGLDPDLLHAPETAGEAAGPEAGNGNENGAASRNGAANGNGERDGGAA
HHHHHHHHHHHHHCCCHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHH
VHRRARLLSGSFVYGMVIQHEHQHDETMLATLQLRAGPPVLADPRAAPPSPAGPVDEAAE
HHHHHHHHCCCEEEEEEECCCCCCCCEEEEEEEECCCCCCCCCCCCCCCCCCCCHHHHHH
VLVPAGEFTMGTSTEPWAYDNERPAHRVFLPAFRLGRYPVTNRAHLAFIADGGYADERLW
HEECCCCEECCCCCCCCCCCCCCCCCEEEHHHHHHCCCCCCCCCEEEEEECCCCCHHHEE
SAEGWAWRCQEGLTAPLFWSRDGDVWTRRRFGRVEPVPLDEPVQHVCWYEAEAHARWAGR
CCCCCEEECCCCCCCCEEECCCCCHHHHHHCCCCCCCCCCHHHHHHHHCCHHHHHHHHCC
RLPTEAEWEKACAHDPVTGRSRRYPWGDTDPTPELANLGHRTARPAPVGGRPAGASPYGA
CCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHCCCCCCCCCCCCCCCCCCCCCCH
EQMIGDVWEWTGGGFTPYPGFASFPYREYSEVFYPRDAAPARFRVLRGGSWATDPSAVRS
HHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCEEEEEECCCCCCCHHHHHH
TFRNWDFPIRRQIFAGFRLARDADTP
HHHCCCCHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MRSGALTGDPTTTRDPAGPTAAPALDAEALAAGLAAARDRSLAYTDLTEDDLLRQHSPLM
CCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCEEECCCCHHHHHHHHCHHH
SPLVWDLAHIGNYEEIWLLRALTGAAELRPGLDDVYDAFRHSRASRTALPLLGPDEARAY
HHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHH
LRDVRGRAMDVLTGLDPDLLHAPETAGEAAGPEAGNGNENGAASRNGAANGNGERDGGAA
HHHHHHHHHHHHHCCCHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHH
VHRRARLLSGSFVYGMVIQHEHQHDETMLATLQLRAGPPVLADPRAAPPSPAGPVDEAAE
HHHHHHHHCCCEEEEEEECCCCCCCCEEEEEEEECCCCCCCCCCCCCCCCCCCCHHHHHH
VLVPAGEFTMGTSTEPWAYDNERPAHRVFLPAFRLGRYPVTNRAHLAFIADGGYADERLW
HEECCCCEECCCCCCCCCCCCCCCCCEEEHHHHHHCCCCCCCCCEEEEEECCCCCHHHEE
SAEGWAWRCQEGLTAPLFWSRDGDVWTRRRFGRVEPVPLDEPVQHVCWYEAEAHARWAGR
CCCCCEEECCCCCCCCEEECCCCCHHHHHHCCCCCCCCCCHHHHHHHHCCHHHHHHHHCC
RLPTEAEWEKACAHDPVTGRSRRYPWGDTDPTPELANLGHRTARPAPVGGRPAGASPYGA
CCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHCCCCCCCCCCCCCCCCCCCCCCH
EQMIGDVWEWTGGGFTPYPGFASFPYREYSEVFYPRDAAPARFRVLRGGSWATDPSAVRS
HHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCEEEEEECCCCCCCHHHHHH
TFRNWDFPIRRQIFAGFRLARDADTP
HHHCCCCHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10192388; 10684935; 10871362 [H]