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The map label for this gene is 158319017

Identifier: 158319017

GI number: 158319017

Start: 8921025

End: 8922443

Strand: Direct

Name: 158319017

Synonym: Franean1_7300

Alternate gene names: NA

Gene position: 8921025-8922443 (Clockwise)

Preceding gene: 158319015

Following gene: 158319018

Centisome position: 99.32

GC content: 77.38

Gene sequence:

>1419_bases
GTGACCCCCGCCACCCCGGGCTCACCGGCTCCGGGCGCGGCCACGACGAACCGGGTAGGCATCGAGACCGAGTGGTTCGT
CGTCGACGTCGCGAACCCGCGCCGGCCCGTCCCCGCGGACGAGACCGCCGCGGCGTTGGAGAGCGTCCTCGCCCCCGGTG
ACCAGGGCCGGCAACCGGACCGAGGCCGGGAGAACCGAGGCCGGGAGAACGGCCAGGCCCGCGACGGCGGCCCGCCGGGC
ACCGACTCGGCCCTGCGGCTTCCCGGCGGCAGCCGGCTCACCTTCGAGCCGGGCGGCCAACTCGAGCTCTCGGGCCCTCC
GCTGGACCTGACCGCCGCCGTGGACGCGATGCGCGCCGACCTCGCGCTCGTCCGCGGCGCCCTCGCCCGGCGCAGGCTCG
GCCTGGTCGGCATGGGTGTCGACCCGCTGCGGACGCCCGTCCGCCACACCACCGCCTCCCGGTACGTGGCCATGGAGCAG
CACTTCCTGGCCCGGGACTGCGACGACGGCCGGACGATGATGTGCTCGACCGCCTCCGTCCAGGTCAACCTGGACATCGG
CACGGACACGGCGCAGGCCGTCGAGCGTTTCCGGCTCGCGCACGCGCTCGAGCCGGTGCTGATCGCCATGTTCGCCGCGT
CGCCGCTGGCCCACGGCCGGCAGATCTCCTGGCAGTCGGGTCGCCAGGCGGTCTGGGCCGGTATCGACGCGAGCCGCACC
GGGCCGGTCCTGCCCGACCCGGCGGCGCCGGCGACGGCGTGGCTCGCCCAGGCGGGCCCGGGCGGGCGCGGCGACGCCCC
CGGCGCGCCGCCCACCGGAGACGCCCAGCTGGCCTGGCTCTGGGCCCGCTACCTGCACGACGCGGACCTCATGATGGTCG
GCGAGCCGGACGGGCGGTACCAGCCGGTCCGGAACCGGACGACCTTCGGGGACTGGATGGCCGGGGCAGGGCCGGTGGCA
CGCCCCCCGACCGCCCAGGACCTCGGCTGGCACGCCACGACGCTGTTCCCGCCCGTCCGGCCACGTGGCTGGCTGGAGCT
GCGTTACCTGGATGCTCAGCCGTCCGACCTGTGGCCGGTGGCCGTCGCCGTGCCGGCGGTGCTCCTCGACGAGCCGGCCG
CCGCCCGGGCCGCGCTCGCCGCGTGCCTCCCGGTCGCCCGGCAGGGGCGGCTGGCGGCCCAGCTCGGCCTGCGGGACCCG
GCACTGCACCGTGCGGCGGTGCGGTGCGTCGACCTGGCCCTGGACACGCTCGCCCGGACGGGCGCCGATCCCGGGCTGCG
GGCCGCGGTGGAGGCCTTCGCCAACCGTTACACGCGGCGGGGGCGCTCCCCGGCCGACGACCTGAACGCGCGTTTCGAGG
CGCGCGGGCCGGCTGAGCTGCTGCGCGAGGAGGCGTCCCAGTGCGTTCCGGTGCCTTGA

Upstream 100 bases:

>100_bases
TCACACAGAGACCACTGTTCCTACTGCGGCTCCAACCGTGGTTGGAGCCGCGACTCCCATCGCCACCTTCGACGATCTCC
TGCGCCTCGCCGTCCGGGAC

Downstream 100 bases:

>100_bases
CCGGCGACCCGACCACCACCCGTGACCCTGCCGGCCCGACGGCCGCTCCTGCCCTCGACGCGGAGGCGCTGGCGGCGGGG
CTGGCGGCGGCCCGGGACCG

Product: glutamate--cysteine ligase GCS2

Products: NA

Alternate protein names: Glutamate/Cysteine Ligase Family Protein; Glutamylcysteine Synthetase; Glutamate-Cysteine Ligase GshA; Gamma-Glutamylcysteine Synthetase; Glutamate-Cysteine Ligase Gsha; Glutamate/Cysteine Ligase; Glutamate-Cysteine Ligase GSHA

Number of amino acids: Translated: 472; Mature: 471

Protein sequence:

>472_residues
MTPATPGSPAPGAATTNRVGIETEWFVVDVANPRRPVPADETAAALESVLAPGDQGRQPDRGRENRGRENGQARDGGPPG
TDSALRLPGGSRLTFEPGGQLELSGPPLDLTAAVDAMRADLALVRGALARRRLGLVGMGVDPLRTPVRHTTASRYVAMEQ
HFLARDCDDGRTMMCSTASVQVNLDIGTDTAQAVERFRLAHALEPVLIAMFAASPLAHGRQISWQSGRQAVWAGIDASRT
GPVLPDPAAPATAWLAQAGPGGRGDAPGAPPTGDAQLAWLWARYLHDADLMMVGEPDGRYQPVRNRTTFGDWMAGAGPVA
RPPTAQDLGWHATTLFPPVRPRGWLELRYLDAQPSDLWPVAVAVPAVLLDEPAAARAALAACLPVARQGRLAAQLGLRDP
ALHRAAVRCVDLALDTLARTGADPGLRAAVEAFANRYTRRGRSPADDLNARFEARGPAELLREEASQCVPVP

Sequences:

>Translated_472_residues
MTPATPGSPAPGAATTNRVGIETEWFVVDVANPRRPVPADETAAALESVLAPGDQGRQPDRGRENRGRENGQARDGGPPG
TDSALRLPGGSRLTFEPGGQLELSGPPLDLTAAVDAMRADLALVRGALARRRLGLVGMGVDPLRTPVRHTTASRYVAMEQ
HFLARDCDDGRTMMCSTASVQVNLDIGTDTAQAVERFRLAHALEPVLIAMFAASPLAHGRQISWQSGRQAVWAGIDASRT
GPVLPDPAAPATAWLAQAGPGGRGDAPGAPPTGDAQLAWLWARYLHDADLMMVGEPDGRYQPVRNRTTFGDWMAGAGPVA
RPPTAQDLGWHATTLFPPVRPRGWLELRYLDAQPSDLWPVAVAVPAVLLDEPAAARAALAACLPVARQGRLAAQLGLRDP
ALHRAAVRCVDLALDTLARTGADPGLRAAVEAFANRYTRRGRSPADDLNARFEARGPAELLREEASQCVPVP
>Mature_471_residues
TPATPGSPAPGAATTNRVGIETEWFVVDVANPRRPVPADETAAALESVLAPGDQGRQPDRGRENRGRENGQARDGGPPGT
DSALRLPGGSRLTFEPGGQLELSGPPLDLTAAVDAMRADLALVRGALARRRLGLVGMGVDPLRTPVRHTTASRYVAMEQH
FLARDCDDGRTMMCSTASVQVNLDIGTDTAQAVERFRLAHALEPVLIAMFAASPLAHGRQISWQSGRQAVWAGIDASRTG
PVLPDPAAPATAWLAQAGPGGRGDAPGAPPTGDAQLAWLWARYLHDADLMMVGEPDGRYQPVRNRTTFGDWMAGAGPVAR
PPTAQDLGWHATTLFPPVRPRGWLELRYLDAQPSDLWPVAVAVPAVLLDEPAAARAALAACLPVARQGRLAAQLGLRDPA
LHRAAVRCVDLALDTLARTGADPGLRAAVEAFANRYTRRGRSPADDLNARFEARGPAELLREEASQCVPVP

Specific function: Unknown

COG id: COG3572

COG function: function code H; Gamma-glutamylcysteine synthetase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 50015; Mature: 49884

Theoretical pI: Translated: 6.88; Mature: 6.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPATPGSPAPGAATTNRVGIETEWFVVDVANPRRPVPADETAAALESVLAPGDQGRQPD
CCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHCCCCCCCCCC
RGRENRGRENGQARDGGPPGTDSALRLPGGSRLTFEPGGQLELSGPPLDLTAAVDAMRAD
CCCHHCCCCCCCCCCCCCCCCCCEEECCCCCEEEECCCCEEEECCCCCCHHHHHHHHHHH
LALVRGALARRRLGLVGMGVDPLRTPVRHTTASRYVAMEQHFLARDCDDGRTMMCSTASV
HHHHHHHHHHHHCCEEECCCCHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEEE
QVNLDIGTDTAQAVERFRLAHALEPVLIAMFAASPLAHGRQISWQSGRQAVWAGIDASRT
EEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCHHCCCCEECCCCCCEEEEECCCCCCC
GPVLPDPAAPATAWLAQAGPGGRGDAPGAPPTGDAQLAWLWARYLHDADLMMVGEPDGRY
CCCCCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCEEEEECCCCCC
QPVRNRTTFGDWMAGAGPVARPPTAQDLGWHATTLFPPVRPRGWLELRYLDAQPSDLWPV
CCCCCCCCCCHHHCCCCCCCCCCCHHHCCCCEEECCCCCCCCCEEEEEEECCCCCCCCHH
AVAVPAVLLDEPAAARAALAACLPVARQGRLAAQLGLRDPALHRAAVRCVDLALDTLART
HHHHHHHHHCCCHHHHHHHHHHHHHHHCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHC
GADPGLRAAVEAFANRYTRRGRSPADDLNARFEARGPAELLREEASQCVPVP
CCCCHHHHHHHHHHHHHHHCCCCCHHHHCCCCCCCCHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
TPATPGSPAPGAATTNRVGIETEWFVVDVANPRRPVPADETAAALESVLAPGDQGRQPD
CCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHCCCCCCCCCC
RGRENRGRENGQARDGGPPGTDSALRLPGGSRLTFEPGGQLELSGPPLDLTAAVDAMRAD
CCCHHCCCCCCCCCCCCCCCCCCEEECCCCCEEEECCCCEEEECCCCCCHHHHHHHHHHH
LALVRGALARRRLGLVGMGVDPLRTPVRHTTASRYVAMEQHFLARDCDDGRTMMCSTASV
HHHHHHHHHHHHCCEEECCCCHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEEE
QVNLDIGTDTAQAVERFRLAHALEPVLIAMFAASPLAHGRQISWQSGRQAVWAGIDASRT
EEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCHHCCCCEECCCCCCEEEEECCCCCCC
GPVLPDPAAPATAWLAQAGPGGRGDAPGAPPTGDAQLAWLWARYLHDADLMMVGEPDGRY
CCCCCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCEEEEECCCCCC
QPVRNRTTFGDWMAGAGPVARPPTAQDLGWHATTLFPPVRPRGWLELRYLDAQPSDLWPV
CCCCCCCCCCHHHCCCCCCCCCCCHHHCCCCEEECCCCCCCCCEEEEEEECCCCCCCCHH
AVAVPAVLLDEPAAARAALAACLPVARQGRLAAQLGLRDPALHRAAVRCVDLALDTLART
HHHHHHHHHCCCHHHHHHHHHHHHHHHCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHC
GADPGLRAAVEAFANRYTRRGRSPADDLNARFEARGPAELLREEASQCVPVP
CCCCHHHHHHHHHHHHHHHCCCCCHHHHCCCCCCCCHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA