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The map label for this gene is nreB [H]

Identifier: 158318941

GI number: 158318941

Start: 8820081

End: 8821865

Strand: Direct

Name: nreB [H]

Synonym: Franean1_7224

Alternate gene names: 158318941

Gene position: 8820081-8821865 (Clockwise)

Preceding gene: 158318938

Following gene: 158318942

Centisome position: 98.2

GC content: 72.44

Gene sequence:

>1785_bases
GTGCCACATCCGTTCCTGCCGCGGCCCCTGACCCGAATGGCCGCCAGGCACCGTTCCGCCGCCCTGACCATCACGGGCAT
CACGACGGTCGCGATCACCGTCGCGGCCCAGTGGCCGGCGTGGTCCACGACGCCGTTCGCCGCCGCGCTGAACGTCTTCG
TCTCCCTCACCTTCGTCCTCACCGGGCTCCTGCTCCTGGACGAGGACGCCCTCGACAGCGTGAGCAGCGCGTTCGTCCTC
GGCGGGGTGCTGTGGACGGCGTCCTGGGCGGCGACCTGGGAGGCCGGCCCGTCCGCTGTGCTCTCCTCGTTCGCCTACAC
CCACTTCTGGGTCTGCCTCGGGTGGGGCGTGCTTCGATACCCGTCAGGACGTCTGCACGACAACAGCGAACGAGTGCTGC
TCGGCACCGCCGTCGCGGTGATCCCGGTGGGCAACCTCGTGCTGATCGCACTGTCCCGCCCGGAGTCCTTCGGCTACGCC
CCCGGCGTGTGGTGGTACGGCTCCGCGATCGACCCGGGCGTGTTCGACATCGTCGTGCACACCCTCGACGCACTGACCCT
CGCGGTCGTCGTCGCCTTCGGCCTGGCCATCGCCCGGCGCTACCGGCGGGCCTCCGCGCTGGAGCGGCGCACCCTCGGGC
CGGTCTCCCTCGGCGTGCTCGCCGCGTTCGCCATAGCCGCGGTGGTGAACCTGTTCGTCTACTACCCGCAGGGCGCCGAG
ATCGATCCGATCTTCATCCCGATAGCACTGGCACTGTTCGCGATCCCGGTGGCATTCGCCGTGGCCGCCGTGCGCCGCCA
TCTCGCCCGGGCCCGCATCGCCCAGCTGCTGAGCGGGCTGAGCACGCCGCCGACGCCGGCGGCCGTCCGCGAGGTGCTGC
GGGCGGCGGTCGGCGACGACGGCGCGGAGCTCTACCTGTGGATGCCCGAACGCGGCTTCCACGTGGACGCCGACGGCCTG
CCGGCCGTCCCGCCCACGGCGGGAGGCACCCAGCTCGCGCTGCCGGTCCGCACCACGGCCGGCGCGCCGCTGGCCGTGCT
CTCCGCGCGCTCGTCGCTGGAACGCGACCGCGACCTGGTCGAGGTCGCGCTGAACGCCAGCGCCATCGCGCTGGAGAACG
CGCGGCTGCACGCCACGGTGACCGCCCAGCTCGACGCCGTCCGCGCGACCCGGACCCGACTCGTCGAGGCCGGGCTCGCC
GAACGCCGGCGGATCGAGCGCGACCTGCACGACGGCGCGCAGCAGCGGCTGCTGGCGCTCTCGGCCCGGCTCGGACTCGC
CCGGGAGCAGTCCACCGACCAGGCCACCGTCGCCGCCCTCGAGGGAGCCCGGGAGGACCTGCGCGCGGCGCTCGCCGAGC
TGCGCGGACTCGCCCGCGGCATCCATCCGCCCGTGCTGAGCGAGAGCGGGCTGAAAGCGGCACTCGAGAATGTCACCGAG
GCCCTCCCCGTGGATGTCGACCTTGATGTGCCTGACGATCGATTCGATACCACGCTGGAGACCACGGCGTACTACACCGT
GAGCGAGGCTCTGGCGAATACCGTCAAACACGCGGATGCCAGCCATGTGCGGGTAACGGTCAAAATGCTCGGCGGCCAGT
TCCTCATCCAGGTGACCGACGACGGGAAGGGCGGTGCGACCATCAGCGGCGGCGGCGGAATCGCCGGCCTCGGCGACCGG
GTCCGCGCACTCGGCGGCGAGTTCACGCTGTCGAGCCCGGAGCGCTGCGGCACCCGGTTGACGGCGAGCATCCCGTGGAG
CAGCGACGCGCGAGGTGGGTGGTGA

Upstream 100 bases:

>100_bases
GGTAGTTCCCACCTTGACGCCTGGGGGGTAACCCTCAGGCCGAAGGGCCTGGTGTGTAACCCTTGTCGAGTGAGATCGTC
GCGATCGGTGGTGGCCTGAG

Downstream 100 bases:

>100_bases
CATGCGGGTAGCGATAGCGGACGATTCAGCGCTGTTCCGGGAAGGCCTCGCGATGCTGCTCAACGCGGCAGGCGTGCAGG
TCATCGCGCAGGCCGCCGAA

Product: integral membrane sensor signal transduction histidine kinase

Products: NA

Alternate protein names: Nitrogen regulation protein B [H]

Number of amino acids: Translated: 594; Mature: 593

Protein sequence:

>594_residues
MPHPFLPRPLTRMAARHRSAALTITGITTVAITVAAQWPAWSTTPFAAALNVFVSLTFVLTGLLLLDEDALDSVSSAFVL
GGVLWTASWAATWEAGPSAVLSSFAYTHFWVCLGWGVLRYPSGRLHDNSERVLLGTAVAVIPVGNLVLIALSRPESFGYA
PGVWWYGSAIDPGVFDIVVHTLDALTLAVVVAFGLAIARRYRRASALERRTLGPVSLGVLAAFAIAAVVNLFVYYPQGAE
IDPIFIPIALALFAIPVAFAVAAVRRHLARARIAQLLSGLSTPPTPAAVREVLRAAVGDDGAELYLWMPERGFHVDADGL
PAVPPTAGGTQLALPVRTTAGAPLAVLSARSSLERDRDLVEVALNASAIALENARLHATVTAQLDAVRATRTRLVEAGLA
ERRRIERDLHDGAQQRLLALSARLGLAREQSTDQATVAALEGAREDLRAALAELRGLARGIHPPVLSESGLKAALENVTE
ALPVDVDLDVPDDRFDTTLETTAYYTVSEALANTVKHADASHVRVTVKMLGGQFLIQVTDDGKGGATISGGGGIAGLGDR
VRALGGEFTLSSPERCGTRLTASIPWSSDARGGW

Sequences:

>Translated_594_residues
MPHPFLPRPLTRMAARHRSAALTITGITTVAITVAAQWPAWSTTPFAAALNVFVSLTFVLTGLLLLDEDALDSVSSAFVL
GGVLWTASWAATWEAGPSAVLSSFAYTHFWVCLGWGVLRYPSGRLHDNSERVLLGTAVAVIPVGNLVLIALSRPESFGYA
PGVWWYGSAIDPGVFDIVVHTLDALTLAVVVAFGLAIARRYRRASALERRTLGPVSLGVLAAFAIAAVVNLFVYYPQGAE
IDPIFIPIALALFAIPVAFAVAAVRRHLARARIAQLLSGLSTPPTPAAVREVLRAAVGDDGAELYLWMPERGFHVDADGL
PAVPPTAGGTQLALPVRTTAGAPLAVLSARSSLERDRDLVEVALNASAIALENARLHATVTAQLDAVRATRTRLVEAGLA
ERRRIERDLHDGAQQRLLALSARLGLAREQSTDQATVAALEGAREDLRAALAELRGLARGIHPPVLSESGLKAALENVTE
ALPVDVDLDVPDDRFDTTLETTAYYTVSEALANTVKHADASHVRVTVKMLGGQFLIQVTDDGKGGATISGGGGIAGLGDR
VRALGGEFTLSSPERCGTRLTASIPWSSDARGGW
>Mature_593_residues
PHPFLPRPLTRMAARHRSAALTITGITTVAITVAAQWPAWSTTPFAAALNVFVSLTFVLTGLLLLDEDALDSVSSAFVLG
GVLWTASWAATWEAGPSAVLSSFAYTHFWVCLGWGVLRYPSGRLHDNSERVLLGTAVAVIPVGNLVLIALSRPESFGYAP
GVWWYGSAIDPGVFDIVVHTLDALTLAVVVAFGLAIARRYRRASALERRTLGPVSLGVLAAFAIAAVVNLFVYYPQGAEI
DPIFIPIALALFAIPVAFAVAAVRRHLARARIAQLLSGLSTPPTPAAVREVLRAAVGDDGAELYLWMPERGFHVDADGLP
AVPPTAGGTQLALPVRTTAGAPLAVLSARSSLERDRDLVEVALNASAIALENARLHATVTAQLDAVRATRTRLVEAGLAE
RRRIERDLHDGAQQRLLALSARLGLAREQSTDQATVAALEGAREDLRAALAELRGLARGIHPPVLSESGLKAALENVTEA
LPVDVDLDVPDDRFDTTLETTAYYTVSEALANTVKHADASHVRVTVKMLGGQFLIQVTDDGKGGATISGGGGIAGLGDRV
RALGGEFTLSSPERCGTRLTASIPWSSDARGGW

Specific function: Member of the two-component regulatory system nreB/nreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. NreB functions as a direct oxygen sensor histidine kinase which is autophosphorylated, in the absence of oxyg

COG id: COG4564

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI87082311, Length=220, Percent_Identity=26.3636363636364, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1787474, Length=228, Percent_Identity=28.9473684210526, Blast_Score=64, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR011712
- InterPro:   IPR005467
- InterPro:   IPR017203 [H]

Pfam domain/function: PF02518 HATPase_c; PF07730 HisKA_3 [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 62819; Mature: 62687

Theoretical pI: Translated: 6.66; Mature: 6.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
0.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPHPFLPRPLTRMAARHRSAALTITGITTVAITVAAQWPAWSTTPFAAALNVFVSLTFVL
CCCCCCCCHHHHHHHHHCCCEEEEEEHEEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHH
TGLLLLDEDALDSVSSAFVLGGVLWTASWAATWEAGPSAVLSSFAYTHFWVCLGWGVLRY
HHHHHCCCHHHHHHHHHHHHHHHHHHCCHHEECCCCHHHHHHHHHHHHHHHHHHCHHHCC
PSGRLHDNSERVLLGTAVAVIPVGNLVLIALSRPESFGYAPGVWWYGSAIDPGVFDIVVH
CCCCCCCCCCEEEEEEHEEEEECCCEEEEEEECCCCCCCCCCCEEECCCCCCHHHHHHHH
TLDALTLAVVVAFGLAIARRYRRASALERRTLGPVSLGVLAAFAIAAVVNLFVYYPQGAE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHEECCCCCC
IDPIFIPIALALFAIPVAFAVAAVRRHLARARIAQLLSGLSTPPTPAAVREVLRAAVGDD
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCC
GAELYLWMPERGFHVDADGLPAVPPTAGGTQLALPVRTTAGAPLAVLSARSSLERDRDLV
CCEEEEEECCCCCEECCCCCCCCCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHH
EVALNASAIALENARLHATVTAQLDAVRATRTRLVEAGLAERRRIERDLHDGAQQRLLAL
HHHHCCCEEEEECCEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SARLGLAREQSTDQATVAALEGAREDLRAALAELRGLARGIHPPVLSESGLKAALENVTE
HHHHCCHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHH
ALPVDVDLDVPDDRFDTTLETTAYYTVSEALANTVKHADASHVRVTVKMLGGQFLIQVTD
HCCCCEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCEEEEEEEC
DGKGGATISGGGGIAGLGDRVRALGGEFTLSSPERCGTRLTASIPWSSDARGGW
CCCCCEEECCCCCCCCCHHHHHHCCCCCCCCCHHHCCCEEEEECCCCCCCCCCC
>Mature Secondary Structure 
PHPFLPRPLTRMAARHRSAALTITGITTVAITVAAQWPAWSTTPFAAALNVFVSLTFVL
CCCCCCCHHHHHHHHHCCCEEEEEEHEEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHH
TGLLLLDEDALDSVSSAFVLGGVLWTASWAATWEAGPSAVLSSFAYTHFWVCLGWGVLRY
HHHHHCCCHHHHHHHHHHHHHHHHHHCCHHEECCCCHHHHHHHHHHHHHHHHHHCHHHCC
PSGRLHDNSERVLLGTAVAVIPVGNLVLIALSRPESFGYAPGVWWYGSAIDPGVFDIVVH
CCCCCCCCCCEEEEEEHEEEEECCCEEEEEEECCCCCCCCCCCEEECCCCCCHHHHHHHH
TLDALTLAVVVAFGLAIARRYRRASALERRTLGPVSLGVLAAFAIAAVVNLFVYYPQGAE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHEECCCCCC
IDPIFIPIALALFAIPVAFAVAAVRRHLARARIAQLLSGLSTPPTPAAVREVLRAAVGDD
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCC
GAELYLWMPERGFHVDADGLPAVPPTAGGTQLALPVRTTAGAPLAVLSARSSLERDRDLV
CCEEEEEECCCCCEECCCCCCCCCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHH
EVALNASAIALENARLHATVTAQLDAVRATRTRLVEAGLAERRRIERDLHDGAQQRLLAL
HHHHCCCEEEEECCEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SARLGLAREQSTDQATVAALEGAREDLRAALAELRGLARGIHPPVLSESGLKAALENVTE
HHHHCCHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHH
ALPVDVDLDVPDDRFDTTLETTAYYTVSEALANTVKHADASHVRVTVKMLGGQFLIQVTD
HCCCCEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCEEEEEEEC
DGKGGATISGGGGIAGLGDRVRALGGEFTLSSPERCGTRLTASIPWSSDARGGW
CCCCCEEECCCCCCCCCHHHHHHCCCCCCCCCHHHCCCEEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA