| Definition | Frankia sp. EAN1pec chromosome, complete genome. |
|---|---|
| Accession | NC_009921 |
| Length | 8,982,042 |
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The map label for this gene is kduD [H]
Identifier: 158318822
GI number: 158318822
Start: 8664103
End: 8664873
Strand: Direct
Name: kduD [H]
Synonym: Franean1_7096
Alternate gene names: 158318822
Gene position: 8664103-8664873 (Clockwise)
Preceding gene: 158318821
Following gene: 158318823
Centisome position: 96.46
GC content: 70.82
Gene sequence:
>771_bases GTGAGGGATCGGTTCGCGCTCGATGGTCAGGTTGCCGTCATCACCGGCGGGGGCACCGGCATCGGCCGGGGTGCGGCGCT CGCGCTCGCCGAGTACGGGGCCGATGTCGTGCTCGCCGCGCGCCGGGTGGAGCCGCTGGAGTCCACGGCCAAGGAGGTCC AGGCGGCGGGCCGGCGAGCGCTTTCGCTGCCGACGGACGTGACCAGCGCGCAGCAGTGCCAGCAGCTCGTTGACACCACG GTGGCAGAGTTCGGGCGGTTCGACATCCTCGTCAACTGTGCCGGCGGTGCGGAGACGAAGTCGATCCGGCGATGGACTGA GGAGGAGTGGCACCAGGTCCTGGCGCTCAACCTCGGCAGCGTGTGGTTCCTCTCCCGTGCAGCCTCGGTGCCGATGCTTC AGCAGGGCAGGGGCGCGATCGTGAACATCTCCTCGGGTGCCAGCCTGCTCGCGATGCCGCAGGCCGCGCCGTACGGCGCG GCGAAGGCCGGGGTCAACAGCCTCACCCGCTCCATGGCCGCTGCCTGGACCGGTAAGGGGATCCGGGTCAACGCCATCGC CGTCGGAGCTGTCCGGGCCGCCACCCTGACCGACGACGCCGCCCGCTATGGGCTCGACCCGGAGGCGATCGGCCTGACCA ACGCCTCGGGCCGCCTCGGGGAACCTGACGAGATCGGCAACGCCGTCCTGTTCTTCGCCTCCGACGCCGCCAGCTTCTGC TCTGGCCAAACCCTTTATGTCCATGGCGGCCCTGGCCCGGCTGGGGTCTGA
Upstream 100 bases:
>100_bases GTACGGGCGACGACATCGCGGCGGTCTGCGCGTTCCTGTGCACCGAGGAGGCCGGCTACCTCACTGGTCAGGTCATCGCT GTCAATGGAGGAGCGGTCAC
Downstream 100 bases:
>100_bases TGCCTTCGCGTATCCGTGACCCATGCCAGATCGGTGCACGCGTCTGAGAAGGAAGCCGTCCTGTGAAGAAGCGGTCTGGC CTCCAAGGGCGGCACGCAGG
Product: short-chain dehydrogenase/reductase SDR
Products: NA
Alternate protein names: 2-keto-3-deoxygluconate 5-dehydrogenase; 2-keto-3-deoxygluconate oxidoreductase; KDG oxidoreductase [H]
Number of amino acids: Translated: 256; Mature: 256
Protein sequence:
>256_residues MRDRFALDGQVAVITGGGTGIGRGAALALAEYGADVVLAARRVEPLESTAKEVQAAGRRALSLPTDVTSAQQCQQLVDTT VAEFGRFDILVNCAGGAETKSIRRWTEEEWHQVLALNLGSVWFLSRAASVPMLQQGRGAIVNISSGASLLAMPQAAPYGA AKAGVNSLTRSMAAAWTGKGIRVNAIAVGAVRAATLTDDAARYGLDPEAIGLTNASGRLGEPDEIGNAVLFFASDAASFC SGQTLYVHGGPGPAGV
Sequences:
>Translated_256_residues MRDRFALDGQVAVITGGGTGIGRGAALALAEYGADVVLAARRVEPLESTAKEVQAAGRRALSLPTDVTSAQQCQQLVDTT VAEFGRFDILVNCAGGAETKSIRRWTEEEWHQVLALNLGSVWFLSRAASVPMLQQGRGAIVNISSGASLLAMPQAAPYGA AKAGVNSLTRSMAAAWTGKGIRVNAIAVGAVRAATLTDDAARYGLDPEAIGLTNASGRLGEPDEIGNAVLFFASDAASFC SGQTLYVHGGPGPAGV >Mature_256_residues MRDRFALDGQVAVITGGGTGIGRGAALALAEYGADVVLAARRVEPLESTAKEVQAAGRRALSLPTDVTSAQQCQQLVDTT VAEFGRFDILVNCAGGAETKSIRRWTEEEWHQVLALNLGSVWFLSRAASVPMLQQGRGAIVNISSGASLLAMPQAAPYGA AKAGVNSLTRSMAAAWTGKGIRVNAIAVGAVRAATLTDDAARYGLDPEAIGLTNASGRLGEPDEIGNAVLFFASDAASFC SGQTLYVHGGPGPAGV
Specific function: Catalyzes the reduction of 2,5-diketo-3-deoxygluconate (DKII or 4,6-dihydroxy-2,5-dioxohexanoate) into 2-keto-3- deoxygluconate (KDG or 2-dehydro-3-deoxygluconate) with a concomitant oxidation of NADH [H]
COG id: COG1028
COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI19923817, Length=250, Percent_Identity=34.8, Blast_Score=148, Evalue=5e-36, Organism=Homo sapiens, GI10190704, Length=249, Percent_Identity=32.9317269076305, Blast_Score=113, Evalue=2e-25, Organism=Homo sapiens, GI32483357, Length=254, Percent_Identity=31.496062992126, Blast_Score=107, Evalue=1e-23, Organism=Homo sapiens, GI59889578, Length=228, Percent_Identity=33.3333333333333, Blast_Score=102, Evalue=2e-22, Organism=Homo sapiens, GI15277342, Length=256, Percent_Identity=30.078125, Blast_Score=97, Evalue=2e-20, Organism=Homo sapiens, GI66933014, Length=248, Percent_Identity=30.6451612903226, Blast_Score=93, Evalue=3e-19, Organism=Homo sapiens, GI40254992, Length=241, Percent_Identity=29.8755186721992, Blast_Score=91, Evalue=2e-18, Organism=Homo sapiens, GI31542939, Length=197, Percent_Identity=35.5329949238579, Blast_Score=87, Evalue=1e-17, Organism=Homo sapiens, GI126723750, Length=257, Percent_Identity=27.2373540856031, Blast_Score=86, Evalue=4e-17, Organism=Homo sapiens, GI4503301, Length=253, Percent_Identity=29.2490118577075, Blast_Score=85, Evalue=5e-17, Organism=Homo sapiens, GI4504505, Length=221, Percent_Identity=30.7692307692308, Blast_Score=85, Evalue=6e-17, Organism=Homo sapiens, GI5031737, Length=248, Percent_Identity=27.8225806451613, Blast_Score=84, Evalue=1e-16, Organism=Homo sapiens, GI4758504, Length=261, Percent_Identity=31.4176245210728, Blast_Score=81, Evalue=9e-16, Organism=Homo sapiens, GI7705925, Length=248, Percent_Identity=30.241935483871, Blast_Score=81, Evalue=1e-15, Organism=Homo sapiens, GI209862901, Length=239, Percent_Identity=29.2887029288703, Blast_Score=80, Evalue=2e-15, Organism=Homo sapiens, GI19923983, Length=239, Percent_Identity=29.2887029288703, Blast_Score=80, Evalue=2e-15, Organism=Homo sapiens, GI7706318, Length=209, Percent_Identity=29.1866028708134, Blast_Score=78, Evalue=6e-15, Organism=Homo sapiens, GI40254986, Length=190, Percent_Identity=31.0526315789474, Blast_Score=76, Evalue=4e-14, Organism=Homo sapiens, GI4557649, Length=190, Percent_Identity=30, Blast_Score=75, Evalue=4e-14, Organism=Homo sapiens, GI33667109, Length=188, Percent_Identity=29.7872340425532, Blast_Score=75, Evalue=5e-14, Organism=Homo sapiens, GI126723191, Length=196, Percent_Identity=29.0816326530612, Blast_Score=75, Evalue=7e-14, Organism=Homo sapiens, GI224922801, Length=172, Percent_Identity=34.8837209302326, Blast_Score=74, Evalue=9e-14, Organism=Homo sapiens, GI83715985, Length=180, Percent_Identity=33.3333333333333, Blast_Score=71, Evalue=9e-13, Organism=Homo sapiens, GI109715829, Length=249, Percent_Identity=26.9076305220884, Blast_Score=69, Evalue=6e-12, Organism=Homo sapiens, GI4503817, Length=174, Percent_Identity=29.8850574712644, Blast_Score=68, Evalue=7e-12, Organism=Homo sapiens, GI142976729, Length=232, Percent_Identity=22.8448275862069, Blast_Score=66, Evalue=3e-11, Organism=Escherichia coli, GI1789208, Length=250, Percent_Identity=40, Blast_Score=152, Evalue=1e-38, Organism=Escherichia coli, GI1787335, Length=247, Percent_Identity=35.2226720647773, Blast_Score=130, Evalue=8e-32, Organism=Escherichia coli, GI1790717, Length=254, Percent_Identity=31.496062992126, Blast_Score=127, Evalue=1e-30, Organism=Escherichia coli, GI1787905, Length=251, Percent_Identity=36.6533864541833, Blast_Score=123, Evalue=1e-29, Organism=Escherichia coli, GI1788459, Length=244, Percent_Identity=31.9672131147541, Blast_Score=110, Evalue=1e-25, Organism=Escherichia coli, GI87082100, Length=251, Percent_Identity=32.2709163346614, Blast_Score=108, Evalue=3e-25, Organism=Escherichia coli, GI1789378, Length=253, Percent_Identity=30.0395256916996, Blast_Score=102, Evalue=3e-23, Organism=Escherichia coli, GI1786812, Length=252, Percent_Identity=31.7460317460317, Blast_Score=100, Evalue=1e-22, Organism=Escherichia coli, GI87082160, Length=249, Percent_Identity=28.9156626506024, Blast_Score=97, Evalue=1e-21, Organism=Escherichia coli, GI1789057, Length=253, Percent_Identity=28.4584980237154, Blast_Score=83, Evalue=2e-17, Organism=Escherichia coli, GI2367175, Length=250, Percent_Identity=29.2, Blast_Score=80, Evalue=1e-16, Organism=Escherichia coli, GI1787526, Length=251, Percent_Identity=25.0996015936255, Blast_Score=74, Evalue=1e-14, Organism=Escherichia coli, GI1787820, Length=182, Percent_Identity=26.3736263736264, Blast_Score=61, Evalue=7e-11, Organism=Caenorhabditis elegans, GI17551412, Length=278, Percent_Identity=34.5323741007194, Blast_Score=125, Evalue=3e-29, Organism=Caenorhabditis elegans, GI17562906, Length=262, Percent_Identity=33.206106870229, Blast_Score=123, Evalue=8e-29, Organism=Caenorhabditis elegans, GI17559104, Length=262, Percent_Identity=36.2595419847328, Blast_Score=123, Evalue=8e-29, Organism=Caenorhabditis elegans, GI71994604, Length=252, Percent_Identity=32.5396825396825, Blast_Score=120, Evalue=6e-28, Organism=Caenorhabditis elegans, GI17562904, Length=269, Percent_Identity=33.0855018587361, Blast_Score=117, Evalue=6e-27, Organism=Caenorhabditis elegans, GI17536651, Length=250, Percent_Identity=30.4, Blast_Score=117, Evalue=6e-27, Organism=Caenorhabditis elegans, GI17555706, Length=247, Percent_Identity=33.1983805668016, Blast_Score=117, Evalue=7e-27, Organism=Caenorhabditis elegans, GI17536025, Length=250, Percent_Identity=32, Blast_Score=114, Evalue=4e-26, Organism=Caenorhabditis elegans, GI71994600, Length=251, Percent_Identity=31.8725099601594, Blast_Score=112, Evalue=2e-25, Organism=Caenorhabditis elegans, GI25147288, Length=250, Percent_Identity=33.2, Blast_Score=111, Evalue=4e-25, Organism=Caenorhabditis elegans, GI17560150, Length=267, Percent_Identity=31.8352059925094, Blast_Score=111, Evalue=4e-25, Organism=Caenorhabditis elegans, GI17562908, Length=265, Percent_Identity=31.6981132075472, Blast_Score=110, Evalue=5e-25, Organism=Caenorhabditis elegans, GI17560220, Length=266, Percent_Identity=31.5789473684211, Blast_Score=110, Evalue=8e-25, Organism=Caenorhabditis elegans, GI17562910, Length=269, Percent_Identity=31.5985130111524, Blast_Score=110, Evalue=1e-24, Organism=Caenorhabditis elegans, GI193204405, Length=266, Percent_Identity=31.5789473684211, Blast_Score=109, Evalue=1e-24, Organism=Caenorhabditis elegans, GI17538480, Length=270, Percent_Identity=32.962962962963, Blast_Score=109, Evalue=1e-24, Organism=Caenorhabditis elegans, GI17560676, Length=250, Percent_Identity=30.8, Blast_Score=108, Evalue=3e-24, Organism=Caenorhabditis elegans, GI17562990, Length=267, Percent_Identity=31.4606741573034, Blast_Score=108, Evalue=3e-24, Organism=Caenorhabditis elegans, GI17544670, Length=275, Percent_Identity=31.2727272727273, Blast_Score=107, Evalue=4e-24, Organism=Caenorhabditis elegans, GI17538486, Length=261, Percent_Identity=32.183908045977, Blast_Score=107, Evalue=9e-24, Organism=Caenorhabditis elegans, GI17560332, Length=261, Percent_Identity=34.0996168582375, Blast_Score=106, Evalue=9e-24, Organism=Caenorhabditis elegans, GI17531453, Length=273, Percent_Identity=30.03663003663, Blast_Score=104, Evalue=4e-23, Organism=Caenorhabditis elegans, GI17561402, Length=252, Percent_Identity=27.7777777777778, Blast_Score=103, Evalue=1e-22, Organism=Caenorhabditis elegans, GI17565030, Length=269, Percent_Identity=32.3420074349442, Blast_Score=98, Evalue=5e-21, Organism=Caenorhabditis elegans, GI115534694, Length=244, Percent_Identity=32.3770491803279, Blast_Score=96, Evalue=2e-20, Organism=Caenorhabditis elegans, GI17561272, Length=257, Percent_Identity=31.1284046692607, Blast_Score=94, Evalue=5e-20, Organism=Caenorhabditis elegans, GI17563726, Length=263, Percent_Identity=28.8973384030418, Blast_Score=93, Evalue=1e-19, Organism=Caenorhabditis elegans, GI72000259, Length=265, Percent_Identity=28.6792452830189, Blast_Score=92, Evalue=2e-19, Organism=Caenorhabditis elegans, GI17538182, Length=258, Percent_Identity=28.2945736434109, Blast_Score=80, Evalue=9e-16, Organism=Caenorhabditis elegans, GI17568967, Length=182, Percent_Identity=30.7692307692308, Blast_Score=78, Evalue=5e-15, Organism=Caenorhabditis elegans, GI17555612, Length=206, Percent_Identity=30.0970873786408, Blast_Score=78, Evalue=6e-15, Organism=Caenorhabditis elegans, GI193203115, Length=166, Percent_Identity=29.5180722891566, Blast_Score=77, Evalue=7e-15, Organism=Caenorhabditis elegans, GI193203117, Length=166, Percent_Identity=29.5180722891566, Blast_Score=77, Evalue=8e-15, Organism=Caenorhabditis elegans, GI71997099, Length=218, Percent_Identity=29.3577981651376, Blast_Score=74, Evalue=5e-14, Organism=Caenorhabditis elegans, GI17564282, Length=161, Percent_Identity=29.1925465838509, Blast_Score=74, Evalue=6e-14, Organism=Caenorhabditis elegans, GI86565303, Length=267, Percent_Identity=27.7153558052434, Blast_Score=70, Evalue=8e-13, Organism=Caenorhabditis elegans, GI71982365, Length=188, Percent_Identity=27.1276595744681, Blast_Score=65, Evalue=3e-11, Organism=Saccharomyces cerevisiae, GI6322861, Length=196, Percent_Identity=32.6530612244898, Blast_Score=88, Evalue=1e-18, Organism=Saccharomyces cerevisiae, GI6324126, Length=249, Percent_Identity=28.9156626506024, Blast_Score=81, Evalue=2e-16, Organism=Saccharomyces cerevisiae, GI6323882, Length=192, Percent_Identity=30.7291666666667, Blast_Score=74, Evalue=2e-14, Organism=Drosophila melanogaster, GI28571526, Length=249, Percent_Identity=38.1526104417671, Blast_Score=146, Evalue=1e-35, Organism=Drosophila melanogaster, GI21357041, Length=253, Percent_Identity=35.5731225296443, Blast_Score=141, Evalue=4e-34, Organism=Drosophila melanogaster, GI24644339, Length=250, Percent_Identity=35.2, Blast_Score=138, Evalue=4e-33, Organism=Drosophila melanogaster, GI23397609, Length=251, Percent_Identity=34.6613545816733, Blast_Score=119, Evalue=2e-27, Organism=Drosophila melanogaster, GI24639444, Length=251, Percent_Identity=31.8725099601594, Blast_Score=108, Evalue=3e-24, Organism=Drosophila melanogaster, GI21355319, Length=250, Percent_Identity=30.8, Blast_Score=104, Evalue=6e-23, Organism=Drosophila melanogaster, GI24644337, Length=248, Percent_Identity=33.4677419354839, Blast_Score=101, Evalue=4e-22, Organism=Drosophila melanogaster, GI24580925, Length=178, Percent_Identity=35.3932584269663, Blast_Score=91, Evalue=1e-18, Organism=Drosophila melanogaster, GI17737361, Length=236, Percent_Identity=31.7796610169492, Blast_Score=85, Evalue=4e-17, Organism=Drosophila melanogaster, GI24584752, Length=190, Percent_Identity=33.6842105263158, Blast_Score=84, Evalue=7e-17, Organism=Drosophila melanogaster, GI21357673, Length=220, Percent_Identity=30.9090909090909, Blast_Score=82, Evalue=3e-16, Organism=Drosophila melanogaster, GI18859837, Length=194, Percent_Identity=30.9278350515464, Blast_Score=82, Evalue=5e-16, Organism=Drosophila melanogaster, GI21358495, Length=236, Percent_Identity=29.2372881355932, Blast_Score=82, Evalue=5e-16, Organism=Drosophila melanogaster, GI24643142, Length=247, Percent_Identity=30.7692307692308, Blast_Score=81, Evalue=6e-16, Organism=Drosophila melanogaster, GI24649181, Length=166, Percent_Identity=30.7228915662651, Blast_Score=73, Evalue=2e-13, Organism=Drosophila melanogaster, GI24640492, Length=159, Percent_Identity=28.3018867924528, Blast_Score=73, Evalue=2e-13, Organism=Drosophila melanogaster, GI21355631, Length=167, Percent_Identity=29.940119760479, Blast_Score=72, Evalue=4e-13, Organism=Drosophila melanogaster, GI24584744, Length=211, Percent_Identity=28.436018957346, Blast_Score=68, Evalue=7e-12, Organism=Drosophila melanogaster, GI28574402, Length=211, Percent_Identity=28.436018957346, Blast_Score=67, Evalue=8e-12, Organism=Drosophila melanogaster, GI281364892, Length=170, Percent_Identity=30.5882352941176, Blast_Score=67, Evalue=8e-12, Organism=Drosophila melanogaster, GI24584748, Length=203, Percent_Identity=27.5862068965517, Blast_Score=66, Evalue=3e-11, Organism=Drosophila melanogaster, GI161076933, Length=203, Percent_Identity=27.5862068965517, Blast_Score=65, Evalue=3e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR011286 - InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 - InterPro: IPR020904 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: =1.1.1.127 [H]
Molecular weight: Translated: 26313; Mature: 26313
Theoretical pI: Translated: 5.83; Mature: 5.83
Prosite motif: PS00061 ADH_SHORT
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.2 %Cys (Translated Protein) 1.6 %Met (Translated Protein) 2.7 %Cys+Met (Translated Protein) 1.2 %Cys (Mature Protein) 1.6 %Met (Mature Protein) 2.7 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MRDRFALDGQVAVITGGGTGIGRGAALALAEYGADVVLAARRVEPLESTAKEVQAAGRRA CCCCEECCCEEEEEECCCCCCCCHHHHHHHHHCCCEEEHHHHCCHHHHHHHHHHHHCCCE LSLPTDVTSAQQCQQLVDTTVAEFGRFDILVNCAGGAETKSIRRWTEEEWHQVLALNLGS ECCCCCCCCHHHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCH VWFLSRAASVPMLQQGRGAIVNISSGASLLAMPQAAPYGAAKAGVNSLTRSMAAAWTGKG HHHHHHHCCCCHHHCCCCEEEEECCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHCCCC IRVNAIAVGAVRAATLTDDAARYGLDPEAIGLTNASGRLGEPDEIGNAVLFFASDAASFC EEEEEEEEEEEEEEHCCCHHHHHCCCCHHEEECCCCCCCCCCHHHCCEEEEEECCHHHHH SGQTLYVHGGPGPAGV CCCEEEEECCCCCCCC >Mature Secondary Structure MRDRFALDGQVAVITGGGTGIGRGAALALAEYGADVVLAARRVEPLESTAKEVQAAGRRA CCCCEECCCEEEEEECCCCCCCCHHHHHHHHHCCCEEEHHHHCCHHHHHHHHHHHHCCCE LSLPTDVTSAQQCQQLVDTTVAEFGRFDILVNCAGGAETKSIRRWTEEEWHQVLALNLGS ECCCCCCCCHHHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCH VWFLSRAASVPMLQQGRGAIVNISSGASLLAMPQAAPYGAAKAGVNSLTRSMAAAWTGKG HHHHHHHCCCCHHHCCCCEEEEECCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHCCCC IRVNAIAVGAVRAATLTDDAARYGLDPEAIGLTNASGRLGEPDEIGNAVLFFASDAASFC EEEEEEEEEEEEEEHCCCHHHHHCCCCHHEEECCCCCCCCCCHHHCCEEEEEECCHHHHH SGQTLYVHGGPGPAGV CCCEEEEECCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 9278503; 2836407; 1766386 [H]