BacMap

Definition	Frankia sp. EAN1pec chromosome, complete genome.
Accession	NC_009921
Length	8,982,042

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The map label for this gene is phbB [H]

Identifier: 158318821

GI number: 158318821

Start: 8663348

End: 8664106

Strand: Direct

Name: phbB [H]

Synonym: Franean1_7095

Alternate gene names: 158318821

Gene position: 8663348-8664106 (Clockwise)

Preceding gene: 158318817

Following gene: 158318822

Centisome position: 96.45

GC content: 69.04

Gene sequence:

>759_bases
ATGAGGAGGCGTAGGTTGAGTTGTGTCGCTGTCGTGACCGGCGGTGCGTCGGGGTTGGGCCTGTCGATCTGCGAGCATCT
CGCCCGGCAGGGACGGGACGTGGGCGTACTCGACCAGGACGTCGACGCCGCCGAGCGGGTGGCTGCCGGTCTGCAGTCGT
GGGGAACTAAGGCGGTAGCGGTCGGGGTCGACGTGGCTGACCGGGCCTCGGTCGCCAAGGCGTTCGATGCGGTGCGCGCC
GAACTCGGGCCGGTCGGGATCCTCGTGACCAGCGCCGGTGTCTCCGGGTTCGTGCCTTTCGAGGAACTGACGATCGACGT
CTGGTCGCGGACCATCGAGGTCAACCTGACGGGGACGTTCACCTGCGTGCAGGCGGCGATCGCGGACATGGTGGCTGCCG
GGTGGGGCCGTATCGTCACCATCTCGTCCGCGGCGGGTCAGACCGGCGTGGCCCGCCAGGCGCACTACGCGGCGTCGAAG
GGCGGCGTCATCGCGCTTACCAAGGCGCTGGCGCTCGAGTACGCGGCCAAGGGGATCACGGTGAACACGATCCCGCCATT
CACCGCCGACACGCCGCTGCTGCGCAGCATGCAGCAGGCGAAGTACCTACCGAGGGCCGAGACGCTGGCACGGATGATCC
CGGCCGGCCGGCTCGGTACGGGCGACGACATCGCGGCGGTCTGCGCGTTCCTGTGCACCGAGGAGGCCGGCTACCTCACT
GGTCAGGTCATCGCTGTCAATGGAGGAGCGGTCACGTGA

Upstream 100 bases:

>100_bases
GTACGTACAGGGCCACTGCAGTTGAGCTCCGAGGATCTTGCGAACCTGGTCCGCCGCCGCGGGGCGGGGCGCAAGGCCTG
CGTTACCGCAGGGACGAGGA

Downstream 100 bases:

>100_bases
GGGATCGGTTCGCGCTCGATGGTCAGGTTGCCGTCATCACCGGCGGGGGCACCGGCATCGGCCGGGGTGCGGCGCTCGCG
CTCGCCGAGTACGGGGCCGA

Product: short-chain dehydrogenase/reductase SDR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 252; Mature: 252

Protein sequence:

>252_residues
MRRRRLSCVAVVTGGASGLGLSICEHLARQGRDVGVLDQDVDAAERVAAGLQSWGTKAVAVGVDVADRASVAKAFDAVRA
ELGPVGILVTSAGVSGFVPFEELTIDVWSRTIEVNLTGTFTCVQAAIADMVAAGWGRIVTISSAAGQTGVARQAHYAASK
GGVIALTKALALEYAAKGITVNTIPPFTADTPLLRSMQQAKYLPRAETLARMIPAGRLGTGDDIAAVCAFLCTEEAGYLT
GQVIAVNGGAVT

Sequences:

>Translated_252_residues
MRRRRLSCVAVVTGGASGLGLSICEHLARQGRDVGVLDQDVDAAERVAAGLQSWGTKAVAVGVDVADRASVAKAFDAVRA
ELGPVGILVTSAGVSGFVPFEELTIDVWSRTIEVNLTGTFTCVQAAIADMVAAGWGRIVTISSAAGQTGVARQAHYAASK
GGVIALTKALALEYAAKGITVNTIPPFTADTPLLRSMQQAKYLPRAETLARMIPAGRLGTGDDIAAVCAFLCTEEAGYLT
GQVIAVNGGAVT
>Mature_252_residues
MRRRRLSCVAVVTGGASGLGLSICEHLARQGRDVGVLDQDVDAAERVAAGLQSWGTKAVAVGVDVADRASVAKAFDAVRA
ELGPVGILVTSAGVSGFVPFEELTIDVWSRTIEVNLTGTFTCVQAAIADMVAAGWGRIVTISSAAGQTGVARQAHYAASK
GGVIALTKALALEYAAKGITVNTIPPFTADTPLLRSMQQAKYLPRAETLARMIPAGRLGTGDDIAAVCAFLCTEEAGYLT
GQVIAVNGGAVT

Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI15277342, Length=258, Percent_Identity=34.8837209302326, Blast_Score=127, Evalue=9e-30,
Organism=Homo sapiens, GI40254992, Length=246, Percent_Identity=32.520325203252, Blast_Score=115, Evalue=5e-26,
Organism=Homo sapiens, GI32483357, Length=242, Percent_Identity=29.3388429752066, Blast_Score=105, Evalue=5e-23,
Organism=Homo sapiens, GI19923817, Length=250, Percent_Identity=28.8, Blast_Score=101, Evalue=5e-22,
Organism=Homo sapiens, GI7705925, Length=245, Percent_Identity=30.6122448979592, Blast_Score=97, Evalue=1e-20,
Organism=Homo sapiens, GI4758504, Length=253, Percent_Identity=31.6205533596838, Blast_Score=92, Evalue=3e-19,
Organism=Homo sapiens, GI66933014, Length=181, Percent_Identity=29.8342541436464, Blast_Score=91, Evalue=9e-19,
Organism=Homo sapiens, GI10190704, Length=261, Percent_Identity=28.735632183908, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI5031737, Length=245, Percent_Identity=31.4285714285714, Blast_Score=89, Evalue=4e-18,
Organism=Homo sapiens, GI31542939, Length=216, Percent_Identity=29.6296296296296, Blast_Score=84, Evalue=9e-17,
Organism=Homo sapiens, GI4503817, Length=187, Percent_Identity=31.5508021390374, Blast_Score=83, Evalue=2e-16,
Organism=Homo sapiens, GI126723750, Length=245, Percent_Identity=26.530612244898, Blast_Score=82, Evalue=4e-16,
Organism=Homo sapiens, GI59889578, Length=152, Percent_Identity=36.1842105263158, Blast_Score=82, Evalue=6e-16,
Organism=Homo sapiens, GI83715985, Length=253, Percent_Identity=29.6442687747036, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI226371731, Length=188, Percent_Identity=31.9148936170213, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI4503301, Length=196, Percent_Identity=29.0816326530612, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI7705855, Length=209, Percent_Identity=27.2727272727273, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI4504505, Length=188, Percent_Identity=33.5106382978723, Blast_Score=75, Evalue=7e-14,
Organism=Homo sapiens, GI40807363, Length=187, Percent_Identity=27.807486631016, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI142976729, Length=184, Percent_Identity=30.4347826086957, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI210032110, Length=172, Percent_Identity=26.7441860465116, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI224922801, Length=168, Percent_Identity=30.952380952381, Blast_Score=70, Evalue=1e-12,
Organism=Homo sapiens, GI25282469, Length=228, Percent_Identity=26.3157894736842, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI7706318, Length=183, Percent_Identity=30.0546448087432, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI33667109, Length=183, Percent_Identity=33.3333333333333, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI4504503, Length=181, Percent_Identity=29.2817679558011, Blast_Score=66, Evalue=4e-11,
Organism=Escherichia coli, GI1787335, Length=241, Percent_Identity=37.344398340249, Blast_Score=146, Evalue=2e-36,
Organism=Escherichia coli, GI1788459, Length=246, Percent_Identity=34.1463414634146, Blast_Score=126, Evalue=1e-30,
Organism=Escherichia coli, GI87082100, Length=247, Percent_Identity=34.412955465587, Blast_Score=124, Evalue=8e-30,
Organism=Escherichia coli, GI1790717, Length=239, Percent_Identity=28.4518828451883, Blast_Score=112, Evalue=2e-26,
Organism=Escherichia coli, GI2367175, Length=248, Percent_Identity=33.0645161290323, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI1789057, Length=257, Percent_Identity=31.5175097276265, Blast_Score=105, Evalue=3e-24,
Organism=Escherichia coli, GI1787905, Length=243, Percent_Identity=32.9218106995885, Blast_Score=100, Evalue=7e-23,
Organism=Escherichia coli, GI1789208, Length=247, Percent_Identity=34.0080971659919, Blast_Score=100, Evalue=9e-23,
Organism=Escherichia coli, GI1786812, Length=194, Percent_Identity=29.3814432989691, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1789378, Length=243, Percent_Identity=29.2181069958848, Blast_Score=81, Evalue=6e-17,
Organism=Escherichia coli, GI87082160, Length=243, Percent_Identity=27.9835390946502, Blast_Score=79, Evalue=2e-16,
Organism=Escherichia coli, GI2367365, Length=240, Percent_Identity=30.4166666666667, Blast_Score=79, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17555706, Length=245, Percent_Identity=34.2857142857143, Blast_Score=122, Evalue=1e-28,
Organism=Caenorhabditis elegans, GI25147288, Length=243, Percent_Identity=34.9794238683128, Blast_Score=110, Evalue=5e-25,
Organism=Caenorhabditis elegans, GI17538182, Length=263, Percent_Identity=34.6007604562738, Blast_Score=100, Evalue=6e-22,
Organism=Caenorhabditis elegans, GI17560676, Length=247, Percent_Identity=27.1255060728745, Blast_Score=97, Evalue=7e-21,
Organism=Caenorhabditis elegans, GI71994604, Length=249, Percent_Identity=28.5140562248996, Blast_Score=95, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI17561402, Length=250, Percent_Identity=28.4, Blast_Score=94, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI71994600, Length=254, Percent_Identity=29.5275590551181, Blast_Score=92, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI17562906, Length=257, Percent_Identity=26.8482490272374, Blast_Score=81, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI17536025, Length=255, Percent_Identity=25.8823529411765, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI193203115, Length=183, Percent_Identity=28.4153005464481, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17564282, Length=242, Percent_Identity=26.0330578512397, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17562910, Length=255, Percent_Identity=26.6666666666667, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI193203117, Length=183, Percent_Identity=28.4153005464481, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17567345, Length=187, Percent_Identity=25.668449197861, Blast_Score=78, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17561272, Length=234, Percent_Identity=27.7777777777778, Blast_Score=78, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17568967, Length=197, Percent_Identity=34.010152284264, Blast_Score=77, Evalue=7e-15,
Organism=Caenorhabditis elegans, GI17536651, Length=255, Percent_Identity=25.8823529411765, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17563726, Length=252, Percent_Identity=26.984126984127, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17559104, Length=260, Percent_Identity=26.1538461538462, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI72000259, Length=256, Percent_Identity=28.515625, Blast_Score=74, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI17538486, Length=260, Percent_Identity=26.1538461538462, Blast_Score=74, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI17544670, Length=264, Percent_Identity=24.2424242424242, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17562908, Length=271, Percent_Identity=26.5682656826568, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17560332, Length=263, Percent_Identity=27.3764258555133, Blast_Score=71, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI17560220, Length=258, Percent_Identity=26.7441860465116, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI193204405, Length=256, Percent_Identity=25, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17562990, Length=252, Percent_Identity=24.2063492063492, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17531453, Length=259, Percent_Identity=25.4826254826255, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17551412, Length=266, Percent_Identity=25.5639097744361, Blast_Score=68, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI17560150, Length=252, Percent_Identity=23.4126984126984, Blast_Score=68, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI17565030, Length=264, Percent_Identity=26.5151515151515, Blast_Score=68, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI17508895, Length=197, Percent_Identity=23.8578680203046, Blast_Score=68, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI17562904, Length=253, Percent_Identity=24.901185770751, Blast_Score=65, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI115534694, Length=249, Percent_Identity=27.710843373494, Blast_Score=65, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6324126, Length=246, Percent_Identity=30.0813008130081, Blast_Score=92, Evalue=8e-20,
Organism=Saccharomyces cerevisiae, GI6322861, Length=205, Percent_Identity=31.7073170731707, Blast_Score=80, Evalue=5e-16,
Organism=Saccharomyces cerevisiae, GI6320089, Length=172, Percent_Identity=26.1627906976744, Blast_Score=64, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24639444, Length=245, Percent_Identity=35.1020408163265, Blast_Score=110, Evalue=1e-24,
Organism=Drosophila melanogaster, GI21355319, Length=245, Percent_Identity=29.7959183673469, Blast_Score=102, Evalue=2e-22,
Organism=Drosophila melanogaster, GI23397609, Length=247, Percent_Identity=30.3643724696356, Blast_Score=90, Evalue=1e-18,
Organism=Drosophila melanogaster, GI17737361, Length=256, Percent_Identity=31.25, Blast_Score=90, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24644339, Length=248, Percent_Identity=29.0322580645161, Blast_Score=89, Evalue=2e-18,
Organism=Drosophila melanogaster, GI21357041, Length=248, Percent_Identity=29.0322580645161, Blast_Score=89, Evalue=3e-18,
Organism=Drosophila melanogaster, GI28571526, Length=244, Percent_Identity=27.4590163934426, Blast_Score=83, Evalue=2e-16,
Organism=Drosophila melanogaster, GI21356301, Length=204, Percent_Identity=28.4313725490196, Blast_Score=81, Evalue=8e-16,
Organism=Drosophila melanogaster, GI24640492, Length=211, Percent_Identity=26.5402843601896, Blast_Score=78, Evalue=5e-15,
Organism=Drosophila melanogaster, GI24649181, Length=183, Percent_Identity=34.4262295081967, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI18859837, Length=235, Percent_Identity=33.1914893617021, Blast_Score=75, Evalue=3e-14,
Organism=Drosophila melanogaster, GI116007236, Length=200, Percent_Identity=31, Blast_Score=75, Evalue=4e-14,
Organism=Drosophila melanogaster, GI24581726, Length=151, Percent_Identity=29.8013245033113, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI116007238, Length=176, Percent_Identity=31.25, Blast_Score=72, Evalue=5e-13,
Organism=Drosophila melanogaster, GI24643142, Length=247, Percent_Identity=27.9352226720648, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI281364892, Length=199, Percent_Identity=26.1306532663317, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI21358495, Length=182, Percent_Identity=29.1208791208791, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI221510726, Length=199, Percent_Identity=27.6381909547739, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24641232, Length=197, Percent_Identity=29.9492385786802, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24584744, Length=214, Percent_Identity=29.9065420560748, Blast_Score=65, Evalue=3e-11,
Organism=Drosophila melanogaster, GI221331218, Length=201, Percent_Identity=27.363184079602, Blast_Score=65, Evalue=3e-11,
Organism=Drosophila melanogaster, GI28574402, Length=214, Percent_Identity=29.9065420560748, Blast_Score=65, Evalue=4e-11,
Organism=Drosophila melanogaster, GI24665243, Length=201, Percent_Identity=27.363184079602, Blast_Score=65, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011283
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.36 [H]

Molecular weight: Translated: 25873; Mature: 25873

Theoretical pI: Translated: 7.25; Mature: 7.25

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRRRLSCVAVVTGGASGLGLSICEHLARQGRDVGVLDQDVDAAERVAAGLQSWGTKAVA
CCCCCEEEEEEEECCCCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCEEEE
VGVDVADRASVAKAFDAVRAELGPVGILVTSAGVSGFVPFEELTIDVWSRTIEVNLTGTF
EECCCHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCHHHHHHEEEEEEEEEEECCHH
TCVQAAIADMVAAGWGRIVTISSAAGQTGVARQAHYAASKGGVIALTKALALEYAAKGIT
HHHHHHHHHHHHCCCCEEEEEECCCCCCCCHHHHHHHCCCCCEEEHHHHHHHHHHHCCCE
VNTIPPFTADTPLLRSMQQAKYLPRAETLARMIPAGRLGTGDDIAAVCAFLCTEEAGYLT
EECCCCCCCCCHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCCEE
GQVIAVNGGAVT
EEEEEECCCCCC
>Mature Secondary Structure
MRRRRLSCVAVVTGGASGLGLSICEHLARQGRDVGVLDQDVDAAERVAAGLQSWGTKAVA
CCCCCEEEEEEEECCCCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCEEEE
VGVDVADRASVAKAFDAVRAELGPVGILVTSAGVSGFVPFEELTIDVWSRTIEVNLTGTF
EECCCHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCHHHHHHEEEEEEEEEEECCHH
TCVQAAIADMVAAGWGRIVTISSAAGQTGVARQAHYAASKGGVIALTKALALEYAAKGIT
HHHHHHHHHHHHCCCCEEEEEECCCCCCCCHHHHHHHCCCCCEEEHHHHHHHHHHHCCCE
VNTIPPFTADTPLLRSMQQAKYLPRAETLARMIPAGRLGTGDDIAAVCAFLCTEEAGYLT
EECCCCCCCCCHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCCEE
GQVIAVNGGAVT
EEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2670935 [H]