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The map label for this gene is yccK [H]

Identifier: 158318311

GI number: 158318311

Start: 8000632

End: 8001681

Strand: Reverse

Name: yccK [H]

Synonym: Franean1_6576

Alternate gene names: 158318311

Gene position: 8001681-8000632 (Counterclockwise)

Preceding gene: 158318312

Following gene: 158318310

Centisome position: 89.09

GC content: 74.67

Gene sequence:

>1050_bases
ATGACCGCGCCAGCGACCCTGCGCACCACCCGACTGGGCCTGACCGACATGTCGATCACTCGGGTCGGGTTCGGCGCCTG
GGCCATCGGCGGGGCGGACTGGGCGTTCGGCTGGGGGCGCCAGGACGACGACGAGGCGGTCGAGGCCATCCGGGCCGCGG
TGCGGTCCGGGGTGAACTGGGTCGACACCGCCGCGGTCTACGGCCTCGGGCACTCCGAGGAGCTCGTCGGCCGGGCGCTG
GCCGGCATCCCCGCCGAGCAACGTCCCTACGTGTTCACCAAGTGCGGCCTGGTCTGGGACGAGAGCGACCCGACGCGGCC
CCCCCTGCGGGTCGGGGCGCCCGCCTCGATCCGCGCCGAGGTGGACGCGTCGCTGCGCCGGCTCGGGGTGGAGCGCATCG
ACCTCTACCAGCTCCACTGGCCGCCGCAGGACGGGACCCCGATCGCCGAGGTTGTCGGCGCCCTGCACGAGCTCCGCGCC
GCGGGCAAGATCCGCGCGGTCGGGGCGTCGAACTTCTCGGTCGCCCAGTTGGAGGCGGCGGCGACGGCGGGCGGTGTCGA
CGTCCTGCAGCCGCCGTTCTCTCTGGTCAACCGACTGGCGGCCGCCGACCTGCTGCCGTACTGCGCCATGCGTGACATCG
GTGTGATCGTCTACAGCCCGATGCAGTCCGGGCTGCTGACGGGCGGGTGGTCGGTGCAGCGCACCCGCGCGCTCGCCGAG
GACGACTGGCGGCGGACGGCGGCGGAGTTCAACCCGCCGGCCCTCGAGCGCAACCTGGCCCTGGTCGATGTGCTGCGTCC
GATAGCGGCCCGGCACGGCACGACGGTGGCCGCGGTGGCCGTCGCCTGGACGCTGGCCTTCGACGGGGTGACCGCCGCGA
TCGTCGGGGCCCGGCGCCCGGACCAGATCGACGCCTGGCTGCCCGCGGGCGGCGCGGTGGTCCTGACCGACCTCGACCTG
GACGAGATCGGCGTCGCGGTCGAACGTCTCGATGTGGGTGCGGGGCCGTCTCGGCAGGGCCCCGCGCTGCCTGGCAGCGC
CCTCGTGTGA

Upstream 100 bases:

>100_bases
CCCGGTAGCCCCGGCTCCGCGCCAGCACAGCCCTGCGCCAGCACAGCCGGCGCCAGCAGGGTCCCGTGCCAGCAGATCCC
CGCACCGTGAGGAGACTCCG

Downstream 100 bases:

>100_bases
GGACTCACAGCGTTCCTCCGGTCATCTGGAGAGGGTGTTCGGGGTGCGCGGTGGCTTCGGTGGAGTGGTCCGTGGCGCAC
CGGCGTGACGAAGTCGATGT

Product: aldo/keto reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 349; Mature: 348

Protein sequence:

>349_residues
MTAPATLRTTRLGLTDMSITRVGFGAWAIGGADWAFGWGRQDDDEAVEAIRAAVRSGVNWVDTAAVYGLGHSEELVGRAL
AGIPAEQRPYVFTKCGLVWDESDPTRPPLRVGAPASIRAEVDASLRRLGVERIDLYQLHWPPQDGTPIAEVVGALHELRA
AGKIRAVGASNFSVAQLEAAATAGGVDVLQPPFSLVNRLAAADLLPYCAMRDIGVIVYSPMQSGLLTGGWSVQRTRALAE
DDWRRTAAEFNPPALERNLALVDVLRPIAARHGTTVAAVAVAWTLAFDGVTAAIVGARRPDQIDAWLPAGGAVVLTDLDL
DEIGVAVERLDVGAGPSRQGPALPGSALV

Sequences:

>Translated_349_residues
MTAPATLRTTRLGLTDMSITRVGFGAWAIGGADWAFGWGRQDDDEAVEAIRAAVRSGVNWVDTAAVYGLGHSEELVGRAL
AGIPAEQRPYVFTKCGLVWDESDPTRPPLRVGAPASIRAEVDASLRRLGVERIDLYQLHWPPQDGTPIAEVVGALHELRA
AGKIRAVGASNFSVAQLEAAATAGGVDVLQPPFSLVNRLAAADLLPYCAMRDIGVIVYSPMQSGLLTGGWSVQRTRALAE
DDWRRTAAEFNPPALERNLALVDVLRPIAARHGTTVAAVAVAWTLAFDGVTAAIVGARRPDQIDAWLPAGGAVVLTDLDL
DEIGVAVERLDVGAGPSRQGPALPGSALV
>Mature_348_residues
TAPATLRTTRLGLTDMSITRVGFGAWAIGGADWAFGWGRQDDDEAVEAIRAAVRSGVNWVDTAAVYGLGHSEELVGRALA
GIPAEQRPYVFTKCGLVWDESDPTRPPLRVGAPASIRAEVDASLRRLGVERIDLYQLHWPPQDGTPIAEVVGALHELRAA
GKIRAVGASNFSVAQLEAAATAGGVDVLQPPFSLVNRLAAADLLPYCAMRDIGVIVYSPMQSGLLTGGWSVQRTRALAED
DWRRTAAEFNPPALERNLALVDVLRPIAARHGTTVAAVAVAWTLAFDGVTAAIVGARRPDQIDAWLPAGGAVVLTDLDLD
EIGVAVERLDVGAGPSRQGPALPGSALV

Specific function: Unknown

COG id: COG0667

COG function: function code C; Predicted oxidoreductases (related to aryl-alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldo/keto reductase 2 family [H]

Homologues:

Organism=Homo sapiens, GI27436964, Length=314, Percent_Identity=27.3885350318471, Blast_Score=83, Evalue=3e-16,
Organism=Homo sapiens, GI27436966, Length=303, Percent_Identity=27.3927392739274, Blast_Score=83, Evalue=5e-16,
Organism=Homo sapiens, GI27436962, Length=303, Percent_Identity=27.0627062706271, Blast_Score=83, Evalue=5e-16,
Organism=Homo sapiens, GI27436969, Length=314, Percent_Identity=24.203821656051, Blast_Score=75, Evalue=8e-14,
Organism=Homo sapiens, GI4504825, Length=314, Percent_Identity=24.203821656051, Blast_Score=75, Evalue=8e-14,
Organism=Homo sapiens, GI41152114, Length=203, Percent_Identity=29.064039408867, Blast_Score=75, Evalue=9e-14,
Organism=Homo sapiens, GI223718702, Length=203, Percent_Identity=28.5714285714286, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI27436971, Length=321, Percent_Identity=24.2990654205607, Blast_Score=69, Evalue=6e-12,
Organism=Homo sapiens, GI41327764, Length=128, Percent_Identity=31.25, Blast_Score=68, Evalue=1e-11,
Organism=Escherichia coli, GI1788070, Length=335, Percent_Identity=36.1194029850746, Blast_Score=192, Evalue=3e-50,
Organism=Escherichia coli, GI87081735, Length=311, Percent_Identity=30.8681672025724, Blast_Score=126, Evalue=2e-30,
Organism=Escherichia coli, GI1788081, Length=269, Percent_Identity=29.7397769516729, Blast_Score=95, Evalue=7e-21,
Organism=Escherichia coli, GI1789375, Length=303, Percent_Identity=29.042904290429, Blast_Score=90, Evalue=3e-19,
Organism=Escherichia coli, GI1789199, Length=326, Percent_Identity=24.8466257668712, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1786400, Length=256, Percent_Identity=26.953125, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI87082198, Length=335, Percent_Identity=24.7761194029851, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1787674, Length=233, Percent_Identity=25.7510729613734, Blast_Score=62, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI212645785, Length=318, Percent_Identity=24.5283018867925, Blast_Score=81, Evalue=8e-16,
Organism=Saccharomyces cerevisiae, GI6325169, Length=299, Percent_Identity=24.0802675585284, Blast_Score=80, Evalue=3e-16,
Organism=Saccharomyces cerevisiae, GI6323998, Length=307, Percent_Identity=26.0586319218241, Blast_Score=67, Evalue=6e-12,
Organism=Drosophila melanogaster, GI24646155, Length=225, Percent_Identity=29.3333333333333, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24646159, Length=178, Percent_Identity=33.1460674157303, Blast_Score=80, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR020471
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 36811; Mature: 36680

Theoretical pI: Translated: 4.83; Mature: 4.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAPATLRTTRLGLTDMSITRVGFGAWAIGGADWAFGWGRQDDDEAVEAIRAAVRSGVNW
CCCCCCEEEEECCCCCCCHHHCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHCCCCH
VDTAAVYGLGHSEELVGRALAGIPAEQRPYVFTKCGLVWDESDPTRPPLRVGAPASIRAE
HHHHHHHCCCCHHHHHHHHHHCCCCCCCCEEEEECCEEECCCCCCCCCEEECCCCCCHHH
VDASLRRLGVERIDLYQLHWPPQDGTPIAEVVGALHELRAAGKIRAVGASNFSVAQLEAA
HHHHHHHCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHCCCEEEECCCCCCHHHHHHH
ATAGGVDVLQPPFSLVNRLAAADLLPYCAMRDIGVIVYSPMQSGLLTGGWSVQRTRALAE
HCCCCCHHCCCCHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCCCCCCCCHHHHHHHHH
DDWRRTAAEFNPPALERNLALVDVLRPIAARHGTTVAAVAVAWTLAFDGVTAAIVGARRP
HHHHHHHHCCCCCHHHHCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCHHHHHHCCCCC
DQIDAWLPAGGAVVLTDLDLDEIGVAVERLDVGAGPSRQGPALPGSALV
CCCCEECCCCCEEEEEECCHHHHHHHHHHEECCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
TAPATLRTTRLGLTDMSITRVGFGAWAIGGADWAFGWGRQDDDEAVEAIRAAVRSGVNW
CCCCCEEEEECCCCCCCHHHCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHCCCCH
VDTAAVYGLGHSEELVGRALAGIPAEQRPYVFTKCGLVWDESDPTRPPLRVGAPASIRAE
HHHHHHHCCCCHHHHHHHHHHCCCCCCCCEEEEECCEEECCCCCCCCCEEECCCCCCHHH
VDASLRRLGVERIDLYQLHWPPQDGTPIAEVVGALHELRAAGKIRAVGASNFSVAQLEAA
HHHHHHHCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHCCCEEEECCCCCCHHHHHHH
ATAGGVDVLQPPFSLVNRLAAADLLPYCAMRDIGVIVYSPMQSGLLTGGWSVQRTRALAE
HCCCCCHHCCCCHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCCCCCCCCHHHHHHHHH
DDWRRTAAEFNPPALERNLALVDVLRPIAARHGTTVAAVAVAWTLAFDGVTAAIVGARRP
HHHHHHHHCCCCCHHHHCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCHHHHHHCCCCC
DQIDAWLPAGGAVVLTDLDLDEIGVAVERLDVGAGPSRQGPALPGSALV
CCCCEECCCCCEEEEEECCHHHHHHHHHHEECCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9274031; 9384377; 9106203 [H]