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The map label for this gene is hsaB [H]

Identifier: 158317981

GI number: 158317981

Start: 7578618

End: 7579130

Strand: Direct

Name: hsaB [H]

Synonym: Franean1_6241

Alternate gene names: 158317981

Gene position: 7578618-7579130 (Clockwise)

Preceding gene: 158317980

Following gene: 158317982

Centisome position: 84.38

GC content: 68.62

Gene sequence:

>513_bases
ATGAGCGGCACACGGCCCCCGAACCACACCGACGACCACACGAACGCCTTCCGGAACGCGCTTGGAACGTTCGCGACGGG
AATCGTGGTCGTCACCGCGTCGCACCCGGCGGACGGTCCCGTGGGTCTCACGGCCAACTCGTTCAGCTCGGTGTCGCTCG
CTCCTCCGCTCGTGCTGTTCTGCGTGGCGCACACCTCCACCACGTGGCCGTCTATCCGGGCCGTGGGCCGGTTCTGCGTG
AACGTCCTCGCCGACGGCCAGGAGGAACTGTCACGCCGGTTCACCGTGCGGGGTGAGGATCGCTTCCGCGGCGTCCCCTG
GCGGCCCGCGCCGTCCGGCGCCCCGATCCTGCCCGGCGTCGCGTCATGGATCGACTGCCGCATCGAGACTCTCCACGAGG
CCGGCGACCACACCATCGTCGTCGGGAAGGTCTGCGATCTCGCGGTCGACGACAAGGGTGCTGCTCCGCTCCTCTACTAC
CGAAGCAGCTACGCCAGCCTGACCGTCAGATAA

Upstream 100 bases:

>100_bases
ACGAGTCACTCCTGGCCGACGGCGTCCACCCCGGCGACGACGGCCACGCGGTCATGGCCGACCGCCTGGAACCCGTCCTG
CGGAAGGCGGGGCCGGGGAC

Downstream 100 bases:

>100_bases
CCATTGATGGTCACGAATCGAACTGGAAGGAGCGTTCTGATGGACGGCGACACCGACCGGAACGGCGAAGAGGAGAGACC
TCGGCAGTTCTTCTTCGACG

Product: flavin reductase domain-containing protein

Products: NAD(+); reduced flavin [C]

Alternate protein names: Flavin:NADH reductase [H]

Number of amino acids: Translated: 170; Mature: 169

Protein sequence:

>170_residues
MSGTRPPNHTDDHTNAFRNALGTFATGIVVVTASHPADGPVGLTANSFSSVSLAPPLVLFCVAHTSTTWPSIRAVGRFCV
NVLADGQEELSRRFTVRGEDRFRGVPWRPAPSGAPILPGVASWIDCRIETLHEAGDHTIVVGKVCDLAVDDKGAAPLLYY
RSSYASLTVR

Sequences:

>Translated_170_residues
MSGTRPPNHTDDHTNAFRNALGTFATGIVVVTASHPADGPVGLTANSFSSVSLAPPLVLFCVAHTSTTWPSIRAVGRFCV
NVLADGQEELSRRFTVRGEDRFRGVPWRPAPSGAPILPGVASWIDCRIETLHEAGDHTIVVGKVCDLAVDDKGAAPLLYY
RSSYASLTVR
>Mature_169_residues
SGTRPPNHTDDHTNAFRNALGTFATGIVVVTASHPADGPVGLTANSFSSVSLAPPLVLFCVAHTSTTWPSIRAVGRFCVN
VLADGQEELSRRFTVRGEDRFRGVPWRPAPSGAPILPGVASWIDCRIETLHEAGDHTIVVGKVCDLAVDDKGAAPLLYYR
SSYASLTVR

Specific function: Catalyzes the reduction of free flavins (FMN or FAD) by NADH. Subsequently, the reduced flavins diffuse to the HsaA oxygenase subunit [H]

COG id: COG1853

COG function: function code R; Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the non-flavoprotein flavin reductase family [H]

Homologues:

Organism=Escherichia coli, GI87081819, Length=164, Percent_Identity=31.0975609756098, Blast_Score=77, Evalue=5e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002563
- InterPro:   IPR012349
- InterPro:   IPR009002 [H]

Pfam domain/function: PF01613 Flavin_Reduct [H]

EC number: 1.6.8.- [C]

Molecular weight: Translated: 18155; Mature: 18023

Theoretical pI: Translated: 7.55; Mature: 7.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGTRPPNHTDDHTNAFRNALGTFATGIVVVTASHPADGPVGLTANSFSSVSLAPPLVLF
CCCCCCCCCCCHHHHHHHHHHHHHHCEEEEEEECCCCCCCCEEECCCCCCCCCCCCEEEE
CVAHTSTTWPSIRAVGRFCVNVLADGQEELSRRFTVRGEDRFRGVPWRPAPSGAPILPGV
EECCCCCCCHHHHHHHHHHHHHHCCCHHHHHHEEECCCCHHCCCCCCCCCCCCCCCCCHH
ASWIDCRIETLHEAGDHTIVVGKVCDLAVDDKGAAPLLYYRSSYASLTVR
HHHHHHHHHHHHCCCCCEEEEEEEEEEEECCCCCCEEEEEECCCEEEEEC
>Mature Secondary Structure 
SGTRPPNHTDDHTNAFRNALGTFATGIVVVTASHPADGPVGLTANSFSSVSLAPPLVLF
CCCCCCCCCCHHHHHHHHHHHHHHCEEEEEEECCCCCCCCEEECCCCCCCCCCCCEEEE
CVAHTSTTWPSIRAVGRFCVNVLADGQEELSRRFTVRGEDRFRGVPWRPAPSGAPILPGV
EECCCCCCCHHHHHHHHHHHHHHCCCHHHHHHEEECCCCHHCCCCCCCCCCCCCCCCCHH
ASWIDCRIETLHEAGDHTIVVGKVCDLAVDDKGAAPLLYYRSSYASLTVR
HHHHHHHHHHHHCCCCCEEEEEEEEEEEECCCCCCEEEEEECCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NADH; flavin [C]

Specific reaction: NADH + flavin = NAD(+) + reduced flavin [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]