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The map label for this gene is nuoE [H]

Identifier: 158317832

GI number: 158317832

Start: 7414608

End: 7415429

Strand: Reverse

Name: nuoE [H]

Synonym: Franean1_6090

Alternate gene names: 158317832

Gene position: 7415429-7414608 (Counterclockwise)

Preceding gene: 158317833

Following gene: 158317831

Centisome position: 82.56

GC content: 73.72

Gene sequence:

>822_bases
ATGCCACTGACCGAACAGACCCGCGCCGCGGCCCGCGAGATCATCGCGCGCTACCCCGAGGGACGTTCCCGCTCGGCGCT
GCTGCCGATGCTGCACCTGGTGCAGTCCGAGCAGGGCGCGGTCACCGCGGAGGGCGTGGAGTTCTGCGCCGAGGAGCTCG
GCATCACCCACGCCGAGGTCAGCGCGGTCGCGACGTTCTACACGATGTACAAGCGCCGCCCGGTCGGCGACTGGCTGGTC
TCCGTCTGCACGAACCTCTCCTGCCTGTTGCGCGGCGGTGAGGAGGTCTACGAGCGCCTGTCGAAGAATCTCGGCGTCGG
GCACGACCAGACCACCGAGGACGGCACGATCACGCTGGAGCACGCCGAGTGCCTGGCGGCCTGTGACTACGCGCCGGTGA
TGACCGTCAACTACGAGTTCTACGACCAGGTCAACCCGGACTCGGCGGAGGAGATCGTCGAGGCCCTGCGGCGCGGCGAG
CGCCCGGCCCCGACCCGCGGCGGCCCGCTGTGTACGTTCGGCGAGTCCTCGTTCCAGCTCGCCGGCTTCGAGGACCCGCG
TCCGGAGGGCGTCGCCGGGCAGGGGGTGGGGACCCCGTCCCTGGCCGGCGTGCTGCTCGCCGAGGCCGCCGGCTGGAAGG
CGGAGGACGGTGTGGCCGGTGCCCCGCCGCTGACCCCGCTGCCCTCGAACGCGCCGCCCTCGGCTGCTTCGGCCCCGGCT
GCGCCGGCGTCGAGCAGCCCCGCATCGTCGAGCGCCGCCGCCCCGGCGAGCCCGGCGCCCGCGCCGGGGACGCCCGGCGT
CCCGCAGACGAAGGTGAACTGA

Upstream 100 bases:

>100_bases
ACCTGCAGGCCGTGCCCGCGCTGACGGAGGGCGGGCAGGTGGCCGACGTGATCGTCGGCGTCGCCTCCGTCGACCCGGTG
CTCGGGGGAGTTGATCGCTG

Downstream 100 bases:

>100_bases
CCATGCCTGTCACCCCGGTCCTCACCCGGCGCTGGACGGCGCCCGAGTCGTGGACGCTGGCGACCTACGAGCGCCTTGAC
GGCTACCAGGGCCTGCGCCG

Product: NADH dehydrogenase subunit E

Products: NA

Alternate protein names: NADH dehydrogenase I subunit E; NDH-1 subunit E [H]

Number of amino acids: Translated: 273; Mature: 272

Protein sequence:

>273_residues
MPLTEQTRAAAREIIARYPEGRSRSALLPMLHLVQSEQGAVTAEGVEFCAEELGITHAEVSAVATFYTMYKRRPVGDWLV
SVCTNLSCLLRGGEEVYERLSKNLGVGHDQTTEDGTITLEHAECLAACDYAPVMTVNYEFYDQVNPDSAEEIVEALRRGE
RPAPTRGGPLCTFGESSFQLAGFEDPRPEGVAGQGVGTPSLAGVLLAEAAGWKAEDGVAGAPPLTPLPSNAPPSAASAPA
APASSSPASSSAAAPASPAPAPGTPGVPQTKVN

Sequences:

>Translated_273_residues
MPLTEQTRAAAREIIARYPEGRSRSALLPMLHLVQSEQGAVTAEGVEFCAEELGITHAEVSAVATFYTMYKRRPVGDWLV
SVCTNLSCLLRGGEEVYERLSKNLGVGHDQTTEDGTITLEHAECLAACDYAPVMTVNYEFYDQVNPDSAEEIVEALRRGE
RPAPTRGGPLCTFGESSFQLAGFEDPRPEGVAGQGVGTPSLAGVLLAEAAGWKAEDGVAGAPPLTPLPSNAPPSAASAPA
APASSSPASSSAAAPASPAPAPGTPGVPQTKVN
>Mature_272_residues
PLTEQTRAAAREIIARYPEGRSRSALLPMLHLVQSEQGAVTAEGVEFCAEELGITHAEVSAVATFYTMYKRRPVGDWLVS
VCTNLSCLLRGGEEVYERLSKNLGVGHDQTTEDGTITLEHAECLAACDYAPVMTVNYEFYDQVNPDSAEEIVEALRRGER
PAPTRGGPLCTFGESSFQLAGFEDPRPEGVAGQGVGTPSLAGVLLAEAAGWKAEDGVAGAPPLTPLPSNAPPSAASAPAA
PASSSPASSSAAAPASPAPAPGTPGVPQTKVN

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be menaquinone. Couples the redox reaction to proton transloca

COG id: COG1905

COG function: function code C; NADH:ubiquinone oxidoreductase 24 kD subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I 24 kDa subunit family [H]

Homologues:

Organism=Homo sapiens, GI222080062, Length=151, Percent_Identity=39.0728476821192, Blast_Score=125, Evalue=5e-29,
Organism=Escherichia coli, GI1788621, Length=134, Percent_Identity=32.089552238806, Blast_Score=79, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17561328, Length=178, Percent_Identity=35.9550561797753, Blast_Score=128, Evalue=4e-30,
Organism=Drosophila melanogaster, GI21355353, Length=160, Percent_Identity=36.25, Blast_Score=122, Evalue=3e-28,
Organism=Drosophila melanogaster, GI18859877, Length=155, Percent_Identity=34.8387096774194, Blast_Score=122, Evalue=3e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002023
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF01257 Complex1_24kDa [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 28315; Mature: 28184

Theoretical pI: Translated: 4.36; Mature: 4.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPLTEQTRAAAREIIARYPEGRSRSALLPMLHLVQSEQGAVTAEGVEFCAEELGITHAEV
CCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCEEHHHHHHHHHHHCCCHHHH
SAVATFYTMYKRRPVGDWLVSVCTNLSCLLRGGEEVYERLSKNLGVGHDQTTEDGTITLE
HHHHHHHHHHHCCCHHHHHHHHHCCHHHHHCCCHHHHHHHHHHCCCCCCCCCCCCEEEEH
HAECLAACDYAPVMTVNYEFYDQVNPDSAEEIVEALRRGERPAPTRGGPLCTFGESSFQL
HHHHHHHCCCCCEEEEEHHHHCCCCCCCHHHHHHHHHCCCCCCCCCCCCEEEECCCCEEE
AGFEDPRPEGVAGQGVGTPSLAGVLLAEAAGWKAEDGVAGAPPLTPLPSNAPPSAASAPA
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
APASSSPASSSAAAPASPAPAPGTPGVPQTKVN
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
PLTEQTRAAAREIIARYPEGRSRSALLPMLHLVQSEQGAVTAEGVEFCAEELGITHAEV
CCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCEEHHHHHHHHHHHCCCHHHH
SAVATFYTMYKRRPVGDWLVSVCTNLSCLLRGGEEVYERLSKNLGVGHDQTTEDGTITLE
HHHHHHHHHHHCCCHHHHHHHHHCCHHHHHCCCHHHHHHHHHHCCCCCCCCCCCCEEEEH
HAECLAACDYAPVMTVNYEFYDQVNPDSAEEIVEALRRGERPAPTRGGPLCTFGESSFQL
HHHHHHHCCCCCEEEEEHHHHCCCCCCCHHHHHHHHHCCCCCCCCCCCCEEEECCCCEEE
AGFEDPRPEGVAGQGVGTPSLAGVLLAEAAGWKAEDGVAGAPPLTPLPSNAPPSAASAPA
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
APASSSPASSSAAAPASPAPAPGTPGVPQTKVN
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]