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The map label for this gene is nuoF [H]

Identifier: 158317831

GI number: 158317831

Start: 7413262

End: 7414605

Strand: Reverse

Name: nuoF [H]

Synonym: Franean1_6089

Alternate gene names: 158317831

Gene position: 7414605-7413262 (Counterclockwise)

Preceding gene: 158317832

Following gene: 158317830

Centisome position: 82.55

GC content: 72.17

Gene sequence:

>1344_bases
ATGCCTGTCACCCCGGTCCTCACCCGGCGCTGGACGGCGCCCGAGTCGTGGACGCTGGCGACCTACGAGCGCCTTGACGG
CTACCAGGGCCTGCGCCGGGCGCTGGCGCAGAGCCCGGACGACCTGATCAAGCTGGTCAAGGACTCCGGCCTGCGCGGTC
GCGGCGGCGCGGGCTTCCCCACCGGTATGAAGTGGGGCTTCATCCCGCAGGGCGACGGCAAACCGCACTACCTCGTCATC
AACGCCGACGAGGGCGAGCCGGGCACCTGCAAGGACGCCCCGCTGATGAAGGCCGACCCGCACTCGCTGATCGAGGGCAT
CGTGATCGCCGCCTACGCGGTGCGCGCGAACCGGGCCTTCATCTACCTGCGCGGCGAGCTGATCCACGCCGGCCGGCGGC
TGCGCGCCGCCGTCGCCGAGGCGTACCGCGCCGGCTACCTGGGACGCGACATCCTCGGTAGCGGGTTCGACCTCGACCTG
GTGGTGCACTCCGGCGCCGGCGCGTACATCTGCGGCGAGGAGACGGCGCTGCTGGACTCGCTGGAGGGCCGGCGCGGCCA
GCCGCGGCTGCGCCCGCCGTTCCCGGCGACCCACGGCCTGTACGCGTCCCCCACGGTCGTGAACAACGTCGAGACGATCG
CCACCGTTCCCTTCATCGTGAACTACGGCGTCGACTGGTTCCGGTCGATGGGCCGCGAGCGCGCCCCGGGCCCGAAGATC
TACAGCCTCTCCGGCCACGTGACCCACCCCGGCCAGTACGAGGCGCCGATGGGCACGACGCTGCGCGAGCTGCTCGACAT
GGCGGGCGGCGTCCTCGGCGGCCGCAAGCTCAAGGCGTGGACCCCGGGCGGCTCGTCGACGCCGCTGCTGACCGCCGACC
ACCTTGACGTCCCGCTGGACTTCGAGGGCGTGCAGGAGGCCGGCTCGCTGCTCGGCACGGCCGCCCTCATGATCATGGAC
GACTCGGTCGACATGCTCAAGATCGTGCGGCGGCTGACCCAGTTCTACGCGCACGAGTCGTGCGGCAAGTGCACCCCGTG
CCGGGAGGGCACCACCTGGATGGTGCAGATCCTGTCCCGGATGGAGCGCGGCCAGGGCGACCCCGACGACGTCGACACCC
TCGTCGACGCCTGCGACAACATCTTCGGACGCGCCTTCTGCGCGCTCGCGGACGGCGCCACCTCGCCGATCGTCTCCGGG
ATCAAGTTCTTCCGGAACGAGTTCCTCCCGATCACCCCGGTGGGGCCGTCGGGTTCCACCACGTCGGTAGCCGGCTCGGC
GAACGGCGCGGCCGCGGGTGGCGCGGCCGCGGGCACGCCGGGCGCCTACGCGGGAGCGCACTGA

Upstream 100 bases:

>100_bases
CGGCGTCGAGCAGCCCCGCATCGTCGAGCGCCGCCGCCCCGGCGAGCCCGGCGCCCGCGCCGGGGACGCCCGGCGTCCCG
CAGACGAAGGTGAACTGACC

Downstream 100 bases:

>100_bases
GATCATGACCGTCGCCCCAGAGAAGCCGGCCGCGCCGGCCGCCCCCAACCACGTCACGCTCACCGTGGACGGGCTCGAGG
TGAGCGTGCCGAAGGGCACC

Product: NADH-quinone oxidoreductase subunit F

Products: NA

Alternate protein names: NADH dehydrogenase I subunit F; NDH-1 subunit F [H]

Number of amino acids: Translated: 447; Mature: 446

Protein sequence:

>447_residues
MPVTPVLTRRWTAPESWTLATYERLDGYQGLRRALAQSPDDLIKLVKDSGLRGRGGAGFPTGMKWGFIPQGDGKPHYLVI
NADEGEPGTCKDAPLMKADPHSLIEGIVIAAYAVRANRAFIYLRGELIHAGRRLRAAVAEAYRAGYLGRDILGSGFDLDL
VVHSGAGAYICGEETALLDSLEGRRGQPRLRPPFPATHGLYASPTVVNNVETIATVPFIVNYGVDWFRSMGRERAPGPKI
YSLSGHVTHPGQYEAPMGTTLRELLDMAGGVLGGRKLKAWTPGGSSTPLLTADHLDVPLDFEGVQEAGSLLGTAALMIMD
DSVDMLKIVRRLTQFYAHESCGKCTPCREGTTWMVQILSRMERGQGDPDDVDTLVDACDNIFGRAFCALADGATSPIVSG
IKFFRNEFLPITPVGPSGSTTSVAGSANGAAAGGAAAGTPGAYAGAH

Sequences:

>Translated_447_residues
MPVTPVLTRRWTAPESWTLATYERLDGYQGLRRALAQSPDDLIKLVKDSGLRGRGGAGFPTGMKWGFIPQGDGKPHYLVI
NADEGEPGTCKDAPLMKADPHSLIEGIVIAAYAVRANRAFIYLRGELIHAGRRLRAAVAEAYRAGYLGRDILGSGFDLDL
VVHSGAGAYICGEETALLDSLEGRRGQPRLRPPFPATHGLYASPTVVNNVETIATVPFIVNYGVDWFRSMGRERAPGPKI
YSLSGHVTHPGQYEAPMGTTLRELLDMAGGVLGGRKLKAWTPGGSSTPLLTADHLDVPLDFEGVQEAGSLLGTAALMIMD
DSVDMLKIVRRLTQFYAHESCGKCTPCREGTTWMVQILSRMERGQGDPDDVDTLVDACDNIFGRAFCALADGATSPIVSG
IKFFRNEFLPITPVGPSGSTTSVAGSANGAAAGGAAAGTPGAYAGAH
>Mature_446_residues
PVTPVLTRRWTAPESWTLATYERLDGYQGLRRALAQSPDDLIKLVKDSGLRGRGGAGFPTGMKWGFIPQGDGKPHYLVIN
ADEGEPGTCKDAPLMKADPHSLIEGIVIAAYAVRANRAFIYLRGELIHAGRRLRAAVAEAYRAGYLGRDILGSGFDLDLV
VHSGAGAYICGEETALLDSLEGRRGQPRLRPPFPATHGLYASPTVVNNVETIATVPFIVNYGVDWFRSMGRERAPGPKIY
SLSGHVTHPGQYEAPMGTTLRELLDMAGGVLGGRKLKAWTPGGSSTPLLTADHLDVPLDFEGVQEAGSLLGTAALMIMDD
SVDMLKIVRRLTQFYAHESCGKCTPCREGTTWMVQILSRMERGQGDPDDVDTLVDACDNIFGRAFCALADGATSPIVSGI
KFFRNEFLPITPVGPSGSTTSVAGSANGAAAGGAAAGTPGAYAGAH

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be menaquinone. Couples the redox reaction to proton transloca

COG id: COG1894

COG function: function code C; NADH:ubiquinone oxidoreductase, NADH-binding (51 kD) subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I 51 kDa subunit family [H]

Homologues:

Organism=Homo sapiens, GI20149568, Length=397, Percent_Identity=49.1183879093199, Blast_Score=390, Evalue=1e-108,
Organism=Homo sapiens, GI260656005, Length=397, Percent_Identity=49.1183879093199, Blast_Score=390, Evalue=1e-108,
Organism=Escherichia coli, GI1788620, Length=394, Percent_Identity=52.5380710659898, Blast_Score=427, Evalue=1e-121,
Organism=Caenorhabditis elegans, GI17531727, Length=385, Percent_Identity=49.3506493506493, Blast_Score=390, Evalue=1e-109,
Organism=Drosophila melanogaster, GI19920794, Length=396, Percent_Identity=48.4848484848485, Blast_Score=394, Evalue=1e-110,
Organism=Drosophila melanogaster, GI45550452, Length=394, Percent_Identity=48.9847715736041, Blast_Score=384, Evalue=1e-106,
Organism=Drosophila melanogaster, GI24653819, Length=376, Percent_Identity=40.9574468085106, Blast_Score=284, Evalue=8e-77,
Organism=Drosophila melanogaster, GI24653817, Length=347, Percent_Identity=39.193083573487, Blast_Score=251, Evalue=1e-66,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001949
- InterPro:   IPR019575
- InterPro:   IPR011537
- InterPro:   IPR011538
- InterPro:   IPR019554 [H]

Pfam domain/function: PF01512 Complex1_51K; PF10589 NADH_4Fe-4S; PF10531 SLBB [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 47500; Mature: 47368

Theoretical pI: Translated: 6.67; Mature: 6.67

Prosite motif: PS00644 COMPLEX1_51K_1 ; PS00645 COMPLEX1_51K_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPVTPVLTRRWTAPESWTLATYERLDGYQGLRRALAQSPDDLIKLVKDSGLRGRGGAGFP
CCCCCCHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCC
TGMKWGFIPQGDGKPHYLVINADEGEPGTCKDAPLMKADPHSLIEGIVIAAYAVRANRAF
CCCCCCCEECCCCCCEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCEEE
IYLRGELIHAGRRLRAAVAEAYRAGYLGRDILGSGFDLDLVVHSGAGAYICGEETALLDS
EEEECHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCEEEEEECCCCEEEECCHHHHHHH
LEGRRGQPRLRPPFPATHGLYASPTVVNNVETIATVPFIVNYGVDWFRSMGRERAPGPKI
HCCCCCCCCCCCCCCCCCCCCCCCHHHCCCHHHHHHHHHHHCCHHHHHHCCCCCCCCCCE
YSLSGHVTHPGQYEAPMGTTLRELLDMAGGVLGGRKLKAWTPGGSSTPLLTADHLDVPLD
EEECCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCEEEECCCCCCCC
FEGVQEAGSLLGTAALMIMDDSVDMLKIVRRLTQFYAHESCGKCTPCREGTTWMVQILSR
HHHHHHHHHHHHHEEEEEECCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHH
MERGQGDPDDVDTLVDACDNIFGRAFCALADGATSPIVSGIKFFRNEFLPITPVGPSGST
HHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCEEEECCCCCCC
TSVAGSANGAAAGGAAAGTPGAYAGAH
CEECCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
PVTPVLTRRWTAPESWTLATYERLDGYQGLRRALAQSPDDLIKLVKDSGLRGRGGAGFP
CCCCCHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCC
TGMKWGFIPQGDGKPHYLVINADEGEPGTCKDAPLMKADPHSLIEGIVIAAYAVRANRAF
CCCCCCCEECCCCCCEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCEEE
IYLRGELIHAGRRLRAAVAEAYRAGYLGRDILGSGFDLDLVVHSGAGAYICGEETALLDS
EEEECHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCEEEEEECCCCEEEECCHHHHHHH
LEGRRGQPRLRPPFPATHGLYASPTVVNNVETIATVPFIVNYGVDWFRSMGRERAPGPKI
HCCCCCCCCCCCCCCCCCCCCCCCHHHCCCHHHHHHHHHHHCCHHHHHHCCCCCCCCCCE
YSLSGHVTHPGQYEAPMGTTLRELLDMAGGVLGGRKLKAWTPGGSSTPLLTADHLDVPLD
EEECCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCEEEECCCCCCCC
FEGVQEAGSLLGTAALMIMDDSVDMLKIVRRLTQFYAHESCGKCTPCREGTTWMVQILSR
HHHHHHHHHHHHHEEEEEECCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHH
MERGQGDPDDVDTLVDACDNIFGRAFCALADGATSPIVSGIKFFRNEFLPITPVGPSGST
HHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCEEEECCCCCCC
TSVAGSANGAAAGGAAAGTPGAYAGAH
CEECCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]