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The map label for this gene is groEL [H]

Identifier: 158317743

GI number: 158317743

Start: 7319731

End: 7321380

Strand: Reverse

Name: groEL [H]

Synonym: Franean1_6001

Alternate gene names: 158317743

Gene position: 7321380-7319731 (Counterclockwise)

Preceding gene: 158317744

Following gene: 158317740

Centisome position: 81.51

GC content: 70.24

Gene sequence:

>1650_bases
ATGCCGAAGATTCTGACGTTCAACGAGGACGCCCGCCGGTCGCTCGAGCGGGGCGTGAACGCCCTCGCGGACGCGGTCAA
GGTGACGATCGGTCCGCGCGGCCGCAACGTCGTCATCAACAAGTCGTACGGCGCGCCGACGATCACCAACGACGGTGTGA
CGATCGCGCGTGAGGTCGAGCTGGACGACCCTTACCAGAACCTGGGGGCGCAGCTCGCCAAGGAGGTCGCCACCAAGACC
AACGACGTCGCCGGCGACGGGACGACGACGGCCACGGTGCTGGCCCAGGAGATGGTCCGCCAGGGCCTGCGGCAGGTGAC
GGCCGGGGCCGCCCCGCTCTCGCTCAAGATCGGCATCGAGGCGGCGGTCGCCGCTGTCTCGTCGGCGCTGCTGGAAGCCG
CGATCGAGATCGGCTCGAAGGAGACCATCGCGCAGGTCGCTGCGATCTCGGCGCAGGACGCCCAGGTCGGCGAACTCATC
GCCGAGGCGATGGACAAGATCGGCAAGGACGGTGTGATCACCATCGAGGAGAGCCAGACCATGGGTCTGGACCTCGAGCT
CACCGAGGGGATGCAGTTCGACAAGGGCTACATCTCGCCGTACTTCGTGACCGACCAGGAGAGCATGGAGGCCGTCCTCG
AGGACGCCTACGTGCTGCTGCACCCTGGCAAGATCAGCGCGCTGAACGACATCCTGCCGATCCTCGAGCAGGTGGTGCAG
GAGCGTAAGCCGCTGCTGATCATCGCTGAGGACGTCGAGGGCGAGGCGCTGTCGACCCTGGTCGTCAACGCGGTGCGCAA
GACCTTCCAGGTCGTCGCGGTGAAGGCCCCCGGCTTCGGTGACCGCCGCAAGGCGATGCTGCAGGACCTCGCGGTCCTGA
CCGGTGGCCAGGTCGTCGCGACCGAGGTGGGTCTCAAGCTCGACTCGATCACGCTCGCCGAGCTCGGCCGGGCGCGGCGG
ATCGTCGTCGACAAGGACCTCACCACGATCGTCGACGGTGCCGGCGACGCCGACGCGGTCGCCGAGCGCGTCCGGCAGAT
GAAGGCGGAGATCGAACTCTCCGACTCGGACTGGGACCGCGAGAAGCTCCAGGAGCGCCTGGCCAAGCTGGCCGGCGGGG
TCGCCGTCATCCGCGTCGGCGCCGCCACCGAGGTCGAGCTCAAGGAGAAGAAGCACCGTCTCGAGGACGCCGTGTCGGCG
ACCCGGGCCGCGGTCGAGGAGGGCATCGTGGCGGGCGGCGGCAGCGCGCTCGTCCACGCGGCCAAGGTCCTCGACGGTGA
CCTCGGCCTGACCGGTGACGAGCGTTCCGGGGTGCGGGTCGTGCGCGCGGCGCTCGACGCGCCGCTCACCTGGATCGCGC
GCAACGCCGGCCTCGAGGGCGCGGTGATCGTGTCCAAGGTCCGCGAGGGCGACGTCGGCCGGGGCTTCAACGCGGCCACC
GGCGAGTACGTCGACCTGGTCGCGGCCGGCGTGGTCGACCCCGTGAAGGTCACCCGCTCCGCGGTGGCGAACGCGGCCTC
CATCGCCGCGCTGCTCATCACCACCGAGAGCCTGGTGGCGGAGAAGCCCGAGGAGGCCGAGGCCGGCCACGGCCACGACC
ACTCGCACGGCGGCCATGGCCACGGCCACTCGCACGGGCCGGGTTTCTGA

Upstream 100 bases:

>100_bases
GGCGTGTCCCACCGGTGGTCCCCTGGTTTCCGCCGGGGGGCCGCGGTGGGGCGCGCCCTTCTTGTTCCCGCCGGCAGCGG
TGTCGGGAGGACACACAGGT

Downstream 100 bases:

>100_bases
GCCGTCGGGTGAGCTGAGCCGTCGGGTGACCGGCGGTGCACGGCCCGGCACCTGTGGCGGGTAGTGCGGTGATTCGGCAG
GTGAGGCCCGGTCGGTCCGC

Product: chaperonin GroEL

Products: NA

Alternate protein names: GroEL protein 1; Protein Cpn60 1 [H]

Number of amino acids: Translated: 549; Mature: 548

Protein sequence:

>549_residues
MPKILTFNEDARRSLERGVNALADAVKVTIGPRGRNVVINKSYGAPTITNDGVTIAREVELDDPYQNLGAQLAKEVATKT
NDVAGDGTTTATVLAQEMVRQGLRQVTAGAAPLSLKIGIEAAVAAVSSALLEAAIEIGSKETIAQVAAISAQDAQVGELI
AEAMDKIGKDGVITIEESQTMGLDLELTEGMQFDKGYISPYFVTDQESMEAVLEDAYVLLHPGKISALNDILPILEQVVQ
ERKPLLIIAEDVEGEALSTLVVNAVRKTFQVVAVKAPGFGDRRKAMLQDLAVLTGGQVVATEVGLKLDSITLAELGRARR
IVVDKDLTTIVDGAGDADAVAERVRQMKAEIELSDSDWDREKLQERLAKLAGGVAVIRVGAATEVELKEKKHRLEDAVSA
TRAAVEEGIVAGGGSALVHAAKVLDGDLGLTGDERSGVRVVRAALDAPLTWIARNAGLEGAVIVSKVREGDVGRGFNAAT
GEYVDLVAAGVVDPVKVTRSAVANAASIAALLITTESLVAEKPEEAEAGHGHDHSHGGHGHGHSHGPGF

Sequences:

>Translated_549_residues
MPKILTFNEDARRSLERGVNALADAVKVTIGPRGRNVVINKSYGAPTITNDGVTIAREVELDDPYQNLGAQLAKEVATKT
NDVAGDGTTTATVLAQEMVRQGLRQVTAGAAPLSLKIGIEAAVAAVSSALLEAAIEIGSKETIAQVAAISAQDAQVGELI
AEAMDKIGKDGVITIEESQTMGLDLELTEGMQFDKGYISPYFVTDQESMEAVLEDAYVLLHPGKISALNDILPILEQVVQ
ERKPLLIIAEDVEGEALSTLVVNAVRKTFQVVAVKAPGFGDRRKAMLQDLAVLTGGQVVATEVGLKLDSITLAELGRARR
IVVDKDLTTIVDGAGDADAVAERVRQMKAEIELSDSDWDREKLQERLAKLAGGVAVIRVGAATEVELKEKKHRLEDAVSA
TRAAVEEGIVAGGGSALVHAAKVLDGDLGLTGDERSGVRVVRAALDAPLTWIARNAGLEGAVIVSKVREGDVGRGFNAAT
GEYVDLVAAGVVDPVKVTRSAVANAASIAALLITTESLVAEKPEEAEAGHGHDHSHGGHGHGHSHGPGF
>Mature_548_residues
PKILTFNEDARRSLERGVNALADAVKVTIGPRGRNVVINKSYGAPTITNDGVTIAREVELDDPYQNLGAQLAKEVATKTN
DVAGDGTTTATVLAQEMVRQGLRQVTAGAAPLSLKIGIEAAVAAVSSALLEAAIEIGSKETIAQVAAISAQDAQVGELIA
EAMDKIGKDGVITIEESQTMGLDLELTEGMQFDKGYISPYFVTDQESMEAVLEDAYVLLHPGKISALNDILPILEQVVQE
RKPLLIIAEDVEGEALSTLVVNAVRKTFQVVAVKAPGFGDRRKAMLQDLAVLTGGQVVATEVGLKLDSITLAELGRARRI
VVDKDLTTIVDGAGDADAVAERVRQMKAEIELSDSDWDREKLQERLAKLAGGVAVIRVGAATEVELKEKKHRLEDAVSAT
RAAVEEGIVAGGGSALVHAAKVLDGDLGLTGDERSGVRVVRAALDAPLTWIARNAGLEGAVIVSKVREGDVGRGFNAATG
EYVDLVAAGVVDPVKVTRSAVANAASIAALLITTESLVAEKPEEAEAGHGHDHSHGGHGHGHSHGPGF

Specific function: Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions [H]

COG id: COG0459

COG function: function code O; Chaperonin GroEL (HSP60 family)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the chaperonin (HSP60) family [H]

Homologues:

Organism=Homo sapiens, GI41399285, Length=525, Percent_Identity=45.9047619047619, Blast_Score=478, Evalue=1e-135,
Organism=Homo sapiens, GI31542947, Length=525, Percent_Identity=45.9047619047619, Blast_Score=478, Evalue=1e-135,
Organism=Homo sapiens, GI5453603, Length=135, Percent_Identity=33.3333333333333, Blast_Score=67, Evalue=5e-11,
Organism=Escherichia coli, GI1790586, Length=523, Percent_Identity=56.5965583173996, Blast_Score=578, Evalue=1e-166,
Organism=Caenorhabditis elegans, GI17555558, Length=526, Percent_Identity=46.5779467680608, Blast_Score=467, Evalue=1e-132,
Organism=Caenorhabditis elegans, GI193210679, Length=218, Percent_Identity=43.5779816513761, Blast_Score=180, Evalue=2e-45,
Organism=Saccharomyces cerevisiae, GI6323288, Length=519, Percent_Identity=49.9036608863198, Blast_Score=494, Evalue=1e-140,
Organism=Saccharomyces cerevisiae, GI6322524, Length=130, Percent_Identity=33.0769230769231, Blast_Score=68, Evalue=5e-12,
Organism=Drosophila melanogaster, GI24641193, Length=525, Percent_Identity=48, Blast_Score=491, Evalue=1e-139,
Organism=Drosophila melanogaster, GI24641191, Length=525, Percent_Identity=48, Blast_Score=491, Evalue=1e-139,
Organism=Drosophila melanogaster, GI45550936, Length=525, Percent_Identity=46.4761904761905, Blast_Score=473, Evalue=1e-133,
Organism=Drosophila melanogaster, GI45550132, Length=525, Percent_Identity=46.4761904761905, Blast_Score=473, Evalue=1e-133,
Organism=Drosophila melanogaster, GI45550935, Length=525, Percent_Identity=46.4761904761905, Blast_Score=473, Evalue=1e-133,
Organism=Drosophila melanogaster, GI17864606, Length=522, Percent_Identity=40.6130268199234, Blast_Score=398, Evalue=1e-111,
Organism=Drosophila melanogaster, GI24584129, Length=527, Percent_Identity=37.1916508538899, Blast_Score=295, Evalue=4e-80,
Organism=Drosophila melanogaster, GI19921262, Length=527, Percent_Identity=37.1916508538899, Blast_Score=295, Evalue=4e-80,
Organism=Drosophila melanogaster, GI24645179, Length=481, Percent_Identity=24.1164241164241, Blast_Score=71, Evalue=2e-12,
Organism=Drosophila melanogaster, GI28571140, Length=563, Percent_Identity=23.9786856127886, Blast_Score=68, Evalue=2e-11,
Organism=Drosophila melanogaster, GI18858175, Length=563, Percent_Identity=23.9786856127886, Blast_Score=68, Evalue=2e-11,

Paralogues:

None

Copy number: 2180 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 360 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 480 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). 15012 Molecules/Cell In: Growth Phase,

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018370
- InterPro:   IPR001844
- InterPro:   IPR002423 [H]

Pfam domain/function: PF00118 Cpn60_TCP1 [H]

EC number: NA

Molecular weight: Translated: 57513; Mature: 57382

Theoretical pI: Translated: 4.67; Mature: 4.67

Prosite motif: PS00296 CHAPERONINS_CPN60

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPKILTFNEDARRSLERGVNALADAVKVTIGPRGRNVVINKSYGAPTITNDGVTIAREVE
CCCEEECCHHHHHHHHHHHHHHHHHHEEEECCCCCEEEEECCCCCCEECCCCEEEEEEEC
LDDPYQNLGAQLAKEVATKTNDVAGDGTTTATVLAQEMVRQGLRQVTAGAAPLSLKIGIE
CCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEECHH
AAVAAVSSALLEAAIEIGSKETIAQVAAISAQDAQVGELIAEAMDKIGKDGVITIEESQT
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCEEEEECCCC
MGLDLELTEGMQFDKGYISPYFVTDQESMEAVLEDAYVLLHPGKISALNDILPILEQVVQ
CCCEEEECCCCCCCCCCCCCEEECCHHHHHHHHHCCEEEEECCCHHHHHHHHHHHHHHHH
ERKPLLIIAEDVEGEALSTLVVNAVRKTFQVVAVKAPGFGDRRKAMLQDLAVLTGGQVVA
CCCCEEEEEECCCCHHHHHHHHHHHHHHEEEEEEECCCCCHHHHHHHHHHHHHCCCEEEE
TEVGLKLDSITLAELGRARRIVVDKDLTTIVDGAGDADAVAERVRQMKAEIELSDSDWDR
EECCCEECCEEHHHHCCCCEEEEECCHHHHHCCCCCHHHHHHHHHHHHHHEEECCCCCCH
EKLQERLAKLAGGVAVIRVGAATEVELKEKKHRLEDAVSATRAAVEEGIVAGGGSALVHA
HHHHHHHHHHHCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHH
AKVLDGDLGLTGDERSGVRVVRAALDAPLTWIARNAGLEGAVIVSKVREGDVGRGFNAAT
HHHHCCCCCCCCCCCCCHHHHHHHHHCCHHHHHHCCCCCCHHEEHHHHCCCCCCCCCCCC
GEYVDLVAAGVVDPVKVTRSAVANAASIAALLITTESLVAEKPEEAEAGHGHDHSHGGHG
CHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCC
HGHSHGPGF
CCCCCCCCC
>Mature Secondary Structure 
PKILTFNEDARRSLERGVNALADAVKVTIGPRGRNVVINKSYGAPTITNDGVTIAREVE
CCEEECCHHHHHHHHHHHHHHHHHHEEEECCCCCEEEEECCCCCCEECCCCEEEEEEEC
LDDPYQNLGAQLAKEVATKTNDVAGDGTTTATVLAQEMVRQGLRQVTAGAAPLSLKIGIE
CCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEECHH
AAVAAVSSALLEAAIEIGSKETIAQVAAISAQDAQVGELIAEAMDKIGKDGVITIEESQT
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCEEEEECCCC
MGLDLELTEGMQFDKGYISPYFVTDQESMEAVLEDAYVLLHPGKISALNDILPILEQVVQ
CCCEEEECCCCCCCCCCCCCEEECCHHHHHHHHHCCEEEEECCCHHHHHHHHHHHHHHHH
ERKPLLIIAEDVEGEALSTLVVNAVRKTFQVVAVKAPGFGDRRKAMLQDLAVLTGGQVVA
CCCCEEEEEECCCCHHHHHHHHHHHHHHEEEEEEECCCCCHHHHHHHHHHHHHCCCEEEE
TEVGLKLDSITLAELGRARRIVVDKDLTTIVDGAGDADAVAERVRQMKAEIELSDSDWDR
EECCCEECCEEHHHHCCCCEEEEECCHHHHHCCCCCHHHHHHHHHHHHHHEEECCCCCCH
EKLQERLAKLAGGVAVIRVGAATEVELKEKKHRLEDAVSATRAAVEEGIVAGGGSALVHA
HHHHHHHHHHHCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHH
AKVLDGDLGLTGDERSGVRVVRAALDAPLTWIARNAGLEGAVIVSKVREGDVGRGFNAAT
HHHHCCCCCCCCCCCCCHHHHHHHHHCCHHHHHHCCCCCCHHEEHHHHCCCCCCCCCCCC
GEYVDLVAAGVVDPVKVTRSAVANAASIAALLITTESLVAEKPEEAEAGHGHDHSHGGHG
CHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCC
HGHSHGPGF
CCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA