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The map label for this gene is add5 [H]

Identifier: 158317675

GI number: 158317675

Start: 7205853

End: 7206947

Strand: Reverse

Name: add5 [H]

Synonym: Franean1_5933

Alternate gene names: 158317675

Gene position: 7206947-7205853 (Counterclockwise)

Preceding gene: 158317676

Following gene: 158317674

Centisome position: 80.24

GC content: 69.5

Gene sequence:

>1095_bases
GTGGACATCCCTGCTGGCCAGGCCAGCGAGAAGATCACTGAGGCTGCGATCCGCCGGGTTCCCAAGGTCCTGCTGCACGA
TCATCTTGATGGTGGCCTGCGGCCCGCGACCATCGTCGAGCTGGCTGACGCCACCGGGTACACCAGGCTGCCGACGACCG
ATGTCGACAAGCTCGGTACCTGGTTCCGCGGAGGTGCGCACACCGGGTCGCTCGTGCGGTACCTGGAGACGTTCAGCCAC
ACGGTGGGCGTCATGCAGACGCCCGAGGCCGTGGCCCGGGTGGCCCGCGAGTGCGCCGAGGATCTGGCCGCCGACGGGGT
CGTCTACGCGGAGGTCCGGTTCGCCCCGGAGCTCCACGTCGAGCAGGGCATGTCGCTCGACGAGGTGGTCGAGGCCGCGT
TGGACGGCTTCCGCGCCGGCTCGGCGGGAACCGGCCTGCACGTGCGCGCGCTGGTGACCGCCATGCGCCACCAGGCCCGC
TCGTTGGAGATCGCGGAGCTGGCCGTCCGGTGGCGGGAGGCCGGGGTGGTCGGGTTCGACATCGCCGGGGCGGAGGCGGG
CAACCCGCCGACCCGCCACCTGGACGCGTTCCAGTACATCCAGCGGGCGAACGGGCACTTCACGATCCACGCGGGTGAGG
CGTTCGGGCTGCCGTCGATCTGGGAGGCGCTGCAGTGGTGCAACGCCGACCGGCTGGGGCACGGCGTGCGCATCGTCGAC
GACATCACGGTCGACCCGGACGGAAACGCCACCCTCGGGGATCTGGCCGACTATGTGCGCGATGTCCGTGTCCCGCTGGA
GATGTGCCCGTCGTCGAACGTGCACACCGGGGCGGCGCCGAGCATCGAGCGCCATCCGATCGGTCTGCTGCGCAGGCTGC
ACTTCCGGGTCACGGTGAACACCGACAACCGGCTGATGAGCGGGGTGACGCTGTCCAGCGAGTTCGCGACCCTGGTCGAG
ACGTTCGGCTACGGCTGGTCCGACATCCGCTGGCTGACCGTGAACGCGATGAAGTCTGCCTTCCTCCCATTTGACCAGCG
TCTCGCGCTGATCAACGAGGTCATCAAGCCCGGCTTCGAGGGGCTCGTCCCGTGA

Upstream 100 bases:

>100_bases
AGGCGGTGCGGGTGCGGTGGATTGGGGCGCGGTGTCTGCTCGTCGTCATGTGGCGGACGGCGAACTGTCGGTGGGGTGGC
CTACCGTCAGGGAGGTGAGC

Downstream 100 bases:

>100_bases
CCGGGTTGTCCGACCTGGCAGCCGGGGTGGACGGGCGGTCGCGGTGTCCCTGGGGGCTGTCGACGCCGCTGTACGTCGAG
TACCACGACACCGAGTGGGG

Product: adenosine deaminase

Products: NA

Alternate protein names: Adenosine aminohydrolase 5 [H]

Number of amino acids: Translated: 364; Mature: 364

Protein sequence:

>364_residues
MDIPAGQASEKITEAAIRRVPKVLLHDHLDGGLRPATIVELADATGYTRLPTTDVDKLGTWFRGGAHTGSLVRYLETFSH
TVGVMQTPEAVARVARECAEDLAADGVVYAEVRFAPELHVEQGMSLDEVVEAALDGFRAGSAGTGLHVRALVTAMRHQAR
SLEIAELAVRWREAGVVGFDIAGAEAGNPPTRHLDAFQYIQRANGHFTIHAGEAFGLPSIWEALQWCNADRLGHGVRIVD
DITVDPDGNATLGDLADYVRDVRVPLEMCPSSNVHTGAAPSIERHPIGLLRRLHFRVTVNTDNRLMSGVTLSSEFATLVE
TFGYGWSDIRWLTVNAMKSAFLPFDQRLALINEVIKPGFEGLVP

Sequences:

>Translated_364_residues
MDIPAGQASEKITEAAIRRVPKVLLHDHLDGGLRPATIVELADATGYTRLPTTDVDKLGTWFRGGAHTGSLVRYLETFSH
TVGVMQTPEAVARVARECAEDLAADGVVYAEVRFAPELHVEQGMSLDEVVEAALDGFRAGSAGTGLHVRALVTAMRHQAR
SLEIAELAVRWREAGVVGFDIAGAEAGNPPTRHLDAFQYIQRANGHFTIHAGEAFGLPSIWEALQWCNADRLGHGVRIVD
DITVDPDGNATLGDLADYVRDVRVPLEMCPSSNVHTGAAPSIERHPIGLLRRLHFRVTVNTDNRLMSGVTLSSEFATLVE
TFGYGWSDIRWLTVNAMKSAFLPFDQRLALINEVIKPGFEGLVP
>Mature_364_residues
MDIPAGQASEKITEAAIRRVPKVLLHDHLDGGLRPATIVELADATGYTRLPTTDVDKLGTWFRGGAHTGSLVRYLETFSH
TVGVMQTPEAVARVARECAEDLAADGVVYAEVRFAPELHVEQGMSLDEVVEAALDGFRAGSAGTGLHVRALVTAMRHQAR
SLEIAELAVRWREAGVVGFDIAGAEAGNPPTRHLDAFQYIQRANGHFTIHAGEAFGLPSIWEALQWCNADRLGHGVRIVD
DITVDPDGNATLGDLADYVRDVRVPLEMCPSSNVHTGAAPSIERHPIGLLRRLHFRVTVNTDNRLMSGVTLSSEFATLVE
TFGYGWSDIRWLTVNAMKSAFLPFDQRLALINEVIKPGFEGLVP

Specific function: Unknown

COG id: COG1816

COG function: function code F; Adenosine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the adenosine and AMP deaminases family [H]

Homologues:

Organism=Homo sapiens, GI47078295, Length=353, Percent_Identity=29.4617563739377, Blast_Score=145, Evalue=8e-35,
Organism=Homo sapiens, GI61175224, Length=254, Percent_Identity=25.1968503937008, Blast_Score=72, Evalue=1e-12,
Organism=Escherichia coli, GI1787910, Length=337, Percent_Identity=30.2670623145401, Blast_Score=150, Evalue=1e-37,
Organism=Caenorhabditis elegans, GI32565969, Length=344, Percent_Identity=29.6511627906977, Blast_Score=122, Evalue=3e-28,
Organism=Caenorhabditis elegans, GI17538512, Length=344, Percent_Identity=29.6511627906977, Blast_Score=122, Evalue=3e-28,
Organism=Drosophila melanogaster, GI24645260, Length=353, Percent_Identity=25.2124645892351, Blast_Score=75, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001365
- InterPro:   IPR006330 [H]

Pfam domain/function: PF00962 A_deaminase [H]

EC number: =3.5.4.4 [H]

Molecular weight: Translated: 39599; Mature: 39599

Theoretical pI: Translated: 5.54; Mature: 5.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDIPAGQASEKITEAAIRRVPKVLLHDHLDGGLRPATIVELADATGYTRLPTTDVDKLGT
CCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHEECCCCCCCCCCCCCHHHHHH
WFRGGAHTGSLVRYLETFSHTVGVMQTPEAVARVARECAEDLAADGVVYAEVRFAPELHV
HHCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCEEEEEEEECCHHHH
EQGMSLDEVVEAALDGFRAGSAGTGLHVRALVTAMRHQARSLEIAELAVRWREAGVVGFD
HCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCEEEEE
IAGAEAGNPPTRHLDAFQYIQRANGHFTIHAGEAFGLPSIWEALQWCNADRLGHGVRIVD
ECCCCCCCCCHHHHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHCCHHHCCCCEEEEE
DITVDPDGNATLGDLADYVRDVRVPLEMCPSSNVHTGAAPSIERHPIGLLRRLHFRVTVN
EEEECCCCCCCHHHHHHHHHHHCCHHHHCCCCCCCCCCCCCCCCCHHHHHHHEEEEEEEC
TDNRLMSGVTLSSEFATLVETFGYGWSDIRWLTVNAMKSAFLPFDQRLALINEVIKPGFE
CCCHHHCCCCCHHHHHHHHHHHCCCCCCEEEEEHHHHHHHCCCHHHHHHHHHHHHCCCCC
GLVP
CCCC
>Mature Secondary Structure
MDIPAGQASEKITEAAIRRVPKVLLHDHLDGGLRPATIVELADATGYTRLPTTDVDKLGT
CCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHEECCCCCCCCCCCCCHHHHHH
WFRGGAHTGSLVRYLETFSHTVGVMQTPEAVARVARECAEDLAADGVVYAEVRFAPELHV
HHCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCEEEEEEEECCHHHH
EQGMSLDEVVEAALDGFRAGSAGTGLHVRALVTAMRHQARSLEIAELAVRWREAGVVGFD
HCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCEEEEE
IAGAEAGNPPTRHLDAFQYIQRANGHFTIHAGEAFGLPSIWEALQWCNADRLGHGVRIVD
ECCCCCCCCCHHHHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHCCHHHCCCCEEEEE
DITVDPDGNATLGDLADYVRDVRVPLEMCPSSNVHTGAAPSIERHPIGLLRRLHFRVTVN
EEEECCCCCCCHHHHHHHHHHHCCHHHHCCCCCCCCCCCCCCCCCHHHHHHHEEEEEEEC
TDNRLMSGVTLSSEFATLVETFGYGWSDIRWLTVNAMKSAFLPFDQRLALINEVIKPGFE
CCCHHHCCCCCHHHHHHHHHHHCCCCCCEEEEEHHHHHHHCCCHHHHHHHHHHHHCCCCC
GLVP
CCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12000953 [H]