Click here to switch to the map view.

The map label for this gene is tag [H]

Identifier: 158317674

GI number: 158317674

Start: 7205230

End: 7205856

Strand: Reverse

Name: tag [H]

Synonym: Franean1_5932

Alternate gene names: 158317674

Gene position: 7205856-7205230 (Counterclockwise)

Preceding gene: 158317675

Following gene: 158317671

Centisome position: 80.23

GC content: 74.64

Gene sequence:

>627_bases
GTGACCGGGTTGTCCGACCTGGCAGCCGGGGTGGACGGGCGGTCGCGGTGTCCCTGGGGGCTGTCGACGCCGCTGTACGT
CGAGTACCACGACACCGAGTGGGGCCGGCCCGTTCGGGACACTGTCGGCCTGTTCGAGCGGATGACGCTGGAGGCGTTCC
AGTCCGGGCTGTCGTGGCTGACGATCCTGCGCAAGCGTCCGGCGTTCCGGGCGGCGTTCGCGGGGTTCGATCCGGCCGCC
GTCGCCGCGTTCGGCGCGGGCACGGTCGAGGAACTTCTCCTGGACGCCGGCATCGTCCGCAACCGGCGCAAGATCGAGGC
GACGATCGCGAACGCCCGCGCGGTGCTCGCCCTGACCGAGCCGCTGGAGGAGCTGGTCTGGTCGTTCGCGCCGCCGTCCC
GTCCGGCCCCGGTCCGGCTCGCCGACGTCCCGGCGGTGACCGCCGAGTCCAAGGCGCTGGCGAAGGCGCTGCGGGGGCAC
GGCTTCGTCTTCGTCGGCCCGACCACCGCGTATGCGCTCATGCAGGCGTGCGGGCTGGTGAACGACCACCTCGCCGGCTG
CGCGGCGCGGGACGCGGCCGTCGAGCCCGCCGCCCAGGCCGCCGGGCTGACCGCGCCTGCGGGCTGA

Upstream 100 bases:

>100_bases
GGCTGACCGTGAACGCGATGAAGTCTGCCTTCCTCCCATTTGACCAGCGTCTCGCGCTGATCAACGAGGTCATCAAGCCC
GGCTTCGAGGGGCTCGTCCC

Downstream 100 bases:

>100_bases
CCGCATCCCCGGCAGCCCGCCGGGTCAGGTCATCCAGCTGCGGGGGCCGAAGGTCTGGACGGAGCGGGCGGCGACCCGTG
AGGCCTCGCCGAGGGCTCCG

Product: DNA-3-methyladenine glycosylase I

Products: NA

Alternate protein names: 3-methyladenine-DNA glycosylase I, constitutive; TAG I; DNA-3-methyladenine glycosidase I; DNA-3-methyladenine glycosylase I [H]

Number of amino acids: Translated: 208; Mature: 207

Protein sequence:

>208_residues
MTGLSDLAAGVDGRSRCPWGLSTPLYVEYHDTEWGRPVRDTVGLFERMTLEAFQSGLSWLTILRKRPAFRAAFAGFDPAA
VAAFGAGTVEELLLDAGIVRNRRKIEATIANARAVLALTEPLEELVWSFAPPSRPAPVRLADVPAVTAESKALAKALRGH
GFVFVGPTTAYALMQACGLVNDHLAGCAARDAAVEPAAQAAGLTAPAG

Sequences:

>Translated_208_residues
MTGLSDLAAGVDGRSRCPWGLSTPLYVEYHDTEWGRPVRDTVGLFERMTLEAFQSGLSWLTILRKRPAFRAAFAGFDPAA
VAAFGAGTVEELLLDAGIVRNRRKIEATIANARAVLALTEPLEELVWSFAPPSRPAPVRLADVPAVTAESKALAKALRGH
GFVFVGPTTAYALMQACGLVNDHLAGCAARDAAVEPAAQAAGLTAPAG
>Mature_207_residues
TGLSDLAAGVDGRSRCPWGLSTPLYVEYHDTEWGRPVRDTVGLFERMTLEAFQSGLSWLTILRKRPAFRAAFAGFDPAAV
AAFGAGTVEELLLDAGIVRNRRKIEATIANARAVLALTEPLEELVWSFAPPSRPAPVRLADVPAVTAESKALAKALRGHG
FVFVGPTTAYALMQACGLVNDHLAGCAARDAAVEPAAQAAGLTAPAG

Specific function: Hydrolysis of the deoxyribose N-glycosidic bond to excise 3-methyladenine from the damaged DNA polymer formed by alkylation lesions [H]

COG id: COG2818

COG function: function code L; 3-methyladenine DNA glycosylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1789971, Length=180, Percent_Identity=50, Blast_Score=187, Evalue=3e-49,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005019
- InterPro:   IPR011257
- InterPro:   IPR004597 [H]

Pfam domain/function: PF03352 Adenine_glyco [H]

EC number: =3.2.2.20 [H]

Molecular weight: Translated: 21897; Mature: 21766

Theoretical pI: Translated: 6.78; Mature: 6.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTGLSDLAAGVDGRSRCPWGLSTPLYVEYHDTEWGRPVRDTVGLFERMTLEAFQSGLSWL
CCCHHHHHHCCCCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
TILRKRPAFRAAFAGFDPAAVAAFGAGTVEELLLDAGIVRNRRKIEATIANARAVLALTE
HHHHHCCHHHHHHCCCCHHHHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHCCHHEEHHHH
PLEELVWSFAPPSRPAPVRLADVPAVTAESKALAKALRGHGFVFVGPTTAYALMQACGLV
HHHHHHHHCCCCCCCCCEEEECCCCCCHHHHHHHHHHHCCCEEEECCHHHHHHHHHHHHH
NDHLAGCAARDAAVEPAAQAAGLTAPAG
HHHHHHHHHHHHHCCHHHHHCCCCCCCC
>Mature Secondary Structure 
TGLSDLAAGVDGRSRCPWGLSTPLYVEYHDTEWGRPVRDTVGLFERMTLEAFQSGLSWL
CCHHHHHHCCCCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
TILRKRPAFRAAFAGFDPAAVAAFGAGTVEELLLDAGIVRNRRKIEATIANARAVLALTE
HHHHHCCHHHHHHCCCCHHHHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHCCHHEEHHHH
PLEELVWSFAPPSRPAPVRLADVPAVTAESKALAKALRGHGFVFVGPTTAYALMQACGLV
HHHHHHHHCCCCCCCCCEEEECCCCCCHHHHHHHHHHHCCCEEEECCHHHHHHHHHHHHH
NDHLAGCAARDAAVEPAAQAAGLTAPAG
HHHHHHHHHHHHHCCHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3536912; 3520491; 8041620; 9278503 [H]