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The map label for this gene is metG [H]

Identifier: 158317640

GI number: 158317640

Start: 7163126

End: 7164823

Strand: Reverse

Name: metG [H]

Synonym: Franean1_5898

Alternate gene names: 158317640

Gene position: 7164823-7163126 (Counterclockwise)

Preceding gene: 158317641

Following gene: 158317639

Centisome position: 79.77

GC content: 70.67

Gene sequence:

>1698_bases
ATGGCTGTGAGCACTCAGACTCCCGACACGGCGGCGCGGCACGGCAGCCGTCCCGTCCTTGTCGCCGTCGCGTGGCCGTA
TGCCAACGGGGCACCGCATCTCGGGCACATCGCCGGCGCCTACCTGCCCGCGGACATCTTCGCCCGCTACCAGCGCATGG
CGGGCAACCGGGTGCTGATGGTCTCGGGGTCCGACGCGCACGGCACCCCGATCACGGTCCGGGCGGACGAGGAGGGCGTC
TCCCCGCAGGAGATCGTCGACCGGTACCACCCGGAGTTCCTGCGCATCTGGTCCGAGCTCGGGATCAGCTTCGACCTTTT
CACGAGCACCCGGACGGACAACCACAGCGCGGTCGCCCAGGACGTGTTCACCCGCCTGCGCGAGGCCGGTTACATCTACG
CCAAGGAGACCTCGCAGTTCTACGACCCGGACGCGGGGCGCTTCCTGCCCGACCGGTACGTCGTCGGCACCTGCCCGCAC
TGCTCGTATCAGCAGGCGCGCGGCGACCAGTGCGAGAACTGCGGGCGCACCCTCGACCCGGAGCTGCTGATCGACCCGCG
CAGCAAGGTGACCGGGGCCGTCCCGGAGATGCGCCAGACGACGCACTTCTTCCTGCGGCTGTCGAGCCTGGCCGACCAGC
TCCTCGACTGGTTGCAGACCCGCCAGGGCTGGCGCCGGCACGTCCTGAACTGGTCGGTGCAGTTCGTCAAGGACGGCCTG
CACGACCGCGCGATCACCCGGGACCTGGACTGGGGCGTCCCGCTGCCGACCGACGAGCTCGGTCCGGGCAAGCGGCTCTA
CGTCTGGTTCGAGGCCGTGATCGGCTACCTGTCGGCGAGCAAGGAGTGGGCGGCCGCCTCGGGTGATCCGGAGGCATGGC
GGGCCTGGTGGGAGGACCCCGAGGCGGCGGCGTACTACTTCGTCGGCAAGGACAACATCCCCTTCCACACCGTCATCTGG
CCGGCGATGCTGATCGGCTACGGCGGCCTGAACCTGCCGACGGACGTCCCGGCGAACCAGTACGTCACCTTCGGCGGGGC
GAAGGCGTCGAAGTCGGCGGGCATCGGGCGCGGGGTGCGCGAGTACCTCGACCTGCTCCAGCCGGACGCGCTGCGCTTCG
CCCTGGCCTCGGTGCTGCCCGAGCAGAACGACACCGAGATCTCGGACGCGGACATCATCCGCCGGGTGAACGACGAGCTG
ATCGCCAACTGGGGCAACCTCGTCAACCGGGTCCTCGCCCAGATCAACAAGTTCTTCGACGGCGAGCTGCCGGAGACCGG
CGAGCTCGACGGCGTGCACGCGGCGCTGCTCGACTCGGTGGACGCCGGCCTCGTCCGGGTCGGCGAGCTGCTGGGCAAGG
TCGAGCAGCGGGCGGCGCTGCGGGCGGCGATGGAGATCTCCGCCGAGGTGAACGCCTACCTCTACCGCGAGGAGCCGTGG
AAGACCGTCAAGGTCGACCGGGCGGCCGCGGCGCGCAGCCTTGCGGTCTCCATCCAGGCGATCTCCGGCATCACCACCGC
GCTGGCCCCGTTCCTGCCGTTCAGCTCGGACCGGGTGGCCGAGGTGCTGGGCATCGACCTCGACGGCTGGGAGCGCCGAC
CCGTCCCGGCCGGTCGTCGCCTCGCGTGGTCCGGCGGCCTGTTCACCAAGCTGGACGTCGGCGCGCTGGACAAGGCCTCG
CTGGACGCCGACGCCTGA

Upstream 100 bases:

>100_bases
CCGGCACGGCCACTGCCACTGCCACGGGCCGCCCGGCCCTCGACCAAGCCGGGCACTCGTCGCCGGTGCCGATCTCGGCT
GACGTCCAGCGGGTAGCTTG

Downstream 100 bases:

>100_bases
CCTGGGCGGCCGCCGTGCCGGGGGCGCCGCCGAACGTGTCGGACCGGCCTGGGAGACTGTGGCGCAATGGCGAGCTCATC
GGGCCCGCCGCCCGTCCTGG

Product: methionyl-tRNA synthetase

Products: NA

Alternate protein names: Methionine--tRNA ligase; MetRS [H]

Number of amino acids: Translated: 565; Mature: 564

Protein sequence:

>565_residues
MAVSTQTPDTAARHGSRPVLVAVAWPYANGAPHLGHIAGAYLPADIFARYQRMAGNRVLMVSGSDAHGTPITVRADEEGV
SPQEIVDRYHPEFLRIWSELGISFDLFTSTRTDNHSAVAQDVFTRLREAGYIYAKETSQFYDPDAGRFLPDRYVVGTCPH
CSYQQARGDQCENCGRTLDPELLIDPRSKVTGAVPEMRQTTHFFLRLSSLADQLLDWLQTRQGWRRHVLNWSVQFVKDGL
HDRAITRDLDWGVPLPTDELGPGKRLYVWFEAVIGYLSASKEWAAASGDPEAWRAWWEDPEAAAYYFVGKDNIPFHTVIW
PAMLIGYGGLNLPTDVPANQYVTFGGAKASKSAGIGRGVREYLDLLQPDALRFALASVLPEQNDTEISDADIIRRVNDEL
IANWGNLVNRVLAQINKFFDGELPETGELDGVHAALLDSVDAGLVRVGELLGKVEQRAALRAAMEISAEVNAYLYREEPW
KTVKVDRAAAARSLAVSIQAISGITTALAPFLPFSSDRVAEVLGIDLDGWERRPVPAGRRLAWSGGLFTKLDVGALDKAS
LDADA

Sequences:

>Translated_565_residues
MAVSTQTPDTAARHGSRPVLVAVAWPYANGAPHLGHIAGAYLPADIFARYQRMAGNRVLMVSGSDAHGTPITVRADEEGV
SPQEIVDRYHPEFLRIWSELGISFDLFTSTRTDNHSAVAQDVFTRLREAGYIYAKETSQFYDPDAGRFLPDRYVVGTCPH
CSYQQARGDQCENCGRTLDPELLIDPRSKVTGAVPEMRQTTHFFLRLSSLADQLLDWLQTRQGWRRHVLNWSVQFVKDGL
HDRAITRDLDWGVPLPTDELGPGKRLYVWFEAVIGYLSASKEWAAASGDPEAWRAWWEDPEAAAYYFVGKDNIPFHTVIW
PAMLIGYGGLNLPTDVPANQYVTFGGAKASKSAGIGRGVREYLDLLQPDALRFALASVLPEQNDTEISDADIIRRVNDEL
IANWGNLVNRVLAQINKFFDGELPETGELDGVHAALLDSVDAGLVRVGELLGKVEQRAALRAAMEISAEVNAYLYREEPW
KTVKVDRAAAARSLAVSIQAISGITTALAPFLPFSSDRVAEVLGIDLDGWERRPVPAGRRLAWSGGLFTKLDVGALDKAS
LDADA
>Mature_564_residues
AVSTQTPDTAARHGSRPVLVAVAWPYANGAPHLGHIAGAYLPADIFARYQRMAGNRVLMVSGSDAHGTPITVRADEEGVS
PQEIVDRYHPEFLRIWSELGISFDLFTSTRTDNHSAVAQDVFTRLREAGYIYAKETSQFYDPDAGRFLPDRYVVGTCPHC
SYQQARGDQCENCGRTLDPELLIDPRSKVTGAVPEMRQTTHFFLRLSSLADQLLDWLQTRQGWRRHVLNWSVQFVKDGLH
DRAITRDLDWGVPLPTDELGPGKRLYVWFEAVIGYLSASKEWAAASGDPEAWRAWWEDPEAAAYYFVGKDNIPFHTVIWP
AMLIGYGGLNLPTDVPANQYVTFGGAKASKSAGIGRGVREYLDLLQPDALRFALASVLPEQNDTEISDADIIRRVNDELI
ANWGNLVNRVLAQINKFFDGELPETGELDGVHAALLDSVDAGLVRVGELLGKVEQRAALRAAMEISAEVNAYLYREEPWK
TVKVDRAAAARSLAVSIQAISGITTALAPFLPFSSDRVAEVLGIDLDGWERRPVPAGRRLAWSGGLFTKLDVGALDKASL
DADA

Specific function: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation [H]

COG id: COG0143

COG function: function code J; Methionyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily [H]

Homologues:

Organism=Homo sapiens, GI14043022, Length=556, Percent_Identity=36.5107913669065, Blast_Score=339, Evalue=3e-93,
Organism=Homo sapiens, GI24308436, Length=569, Percent_Identity=26.8892794376098, Blast_Score=160, Evalue=4e-39,
Organism=Escherichia coli, GI1788432, Length=555, Percent_Identity=34.0540540540541, Blast_Score=313, Evalue=1e-86,
Organism=Caenorhabditis elegans, GI17540794, Length=553, Percent_Identity=33.996383363472, Blast_Score=325, Evalue=3e-89,
Organism=Caenorhabditis elegans, GI212645096, Length=539, Percent_Identity=24.4897959183673, Blast_Score=144, Evalue=2e-34,
Organism=Caenorhabditis elegans, GI71992781, Length=439, Percent_Identity=23.4624145785877, Blast_Score=101, Evalue=1e-21,
Organism=Saccharomyces cerevisiae, GI6321704, Length=579, Percent_Identity=33.5060449050086, Blast_Score=348, Evalue=2e-96,
Organism=Saccharomyces cerevisiae, GI6321610, Length=539, Percent_Identity=23.5621521335807, Blast_Score=134, Evalue=4e-32,
Organism=Drosophila melanogaster, GI24655311, Length=567, Percent_Identity=34.2151675485009, Blast_Score=323, Evalue=2e-88,
Organism=Drosophila melanogaster, GI21358483, Length=531, Percent_Identity=24.8587570621469, Blast_Score=117, Evalue=2e-26,
Organism=Drosophila melanogaster, GI21355409, Length=209, Percent_Identity=28.7081339712919, Blast_Score=68, Evalue=2e-11,

Paralogues:

None

Copy number: 871 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015413
- InterPro:   IPR014758
- InterPro:   IPR014729
- InterPro:   IPR009080 [H]

Pfam domain/function: PF09334 tRNA-synt_1g [H]

EC number: =6.1.1.10 [H]

Molecular weight: Translated: 62332; Mature: 62201

Theoretical pI: Translated: 5.02; Mature: 5.02

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVSTQTPDTAARHGSRPVLVAVAWPYANGAPHLGHIAGAYLPADIFARYQRMAGNRVLM
CCCCCCCCCHHHHCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEE
VSGSDAHGTPITVRADEEGVSPQEIVDRYHPEFLRIWSELGISFDLFTSTRTDNHSAVAQ
EECCCCCCCCEEEECCCCCCCHHHHHHHHCHHHHHHHHHHCCEEEEEECCCCCCHHHHHH
DVFTRLREAGYIYAKETSQFYDPDAGRFLPDRYVVGTCPHCSYQQARGDQCENCGRTLDP
HHHHHHHHCCEEEEECCCCCCCCCCCCCCCCCCEEECCCCCCHHHHCCCHHHHCCCCCCC
ELLIDPRSKVTGAVPEMRQTTHFFLRLSSLADQLLDWLQTRQGWRRHVLNWSVQFVKDGL
CEEECCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
HDRAITRDLDWGVPLPTDELGPGKRLYVWFEAVIGYLSASKEWAAASGDPEAWRAWWEDP
HHHHHHCCCCCCCCCCCCCCCCCCEEEHHHHHHHHHHHCCCCCCCCCCCHHHHHHHCCCC
EAAAYYFVGKDNIPFHTVIWPAMLIGYGGLNLPTDVPANQYVTFGGAKASKSAGIGRGVR
CCEEEEEEECCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCEEEECCCCCCCCCCCHHHHH
EYLDLLQPDALRFALASVLPEQNDTEISDADIIRRVNDELIANWGNLVNRVLAQINKFFD
HHHHHHCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GELPETGELDGVHAALLDSVDAGLVRVGELLGKVEQRAALRAAMEISAEVNAYLYREEPW
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCC
KTVKVDRAAAARSLAVSIQAISGITTALAPFLPFSSDRVAEVLGIDLDGWERRPVPAGRR
CEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCCCCCCCCCCCCE
LAWSGGLFTKLDVGALDKASLDADA
EEECCCCEEEECCCCCCCCCCCCCC
>Mature Secondary Structure 
AVSTQTPDTAARHGSRPVLVAVAWPYANGAPHLGHIAGAYLPADIFARYQRMAGNRVLM
CCCCCCCCHHHHCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEE
VSGSDAHGTPITVRADEEGVSPQEIVDRYHPEFLRIWSELGISFDLFTSTRTDNHSAVAQ
EECCCCCCCCEEEECCCCCCCHHHHHHHHCHHHHHHHHHHCCEEEEEECCCCCCHHHHHH
DVFTRLREAGYIYAKETSQFYDPDAGRFLPDRYVVGTCPHCSYQQARGDQCENCGRTLDP
HHHHHHHHCCEEEEECCCCCCCCCCCCCCCCCCEEECCCCCCHHHHCCCHHHHCCCCCCC
ELLIDPRSKVTGAVPEMRQTTHFFLRLSSLADQLLDWLQTRQGWRRHVLNWSVQFVKDGL
CEEECCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
HDRAITRDLDWGVPLPTDELGPGKRLYVWFEAVIGYLSASKEWAAASGDPEAWRAWWEDP
HHHHHHCCCCCCCCCCCCCCCCCCEEEHHHHHHHHHHHCCCCCCCCCCCHHHHHHHCCCC
EAAAYYFVGKDNIPFHTVIWPAMLIGYGGLNLPTDVPANQYVTFGGAKASKSAGIGRGVR
CCEEEEEEECCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCEEEECCCCCCCCCCCHHHHH
EYLDLLQPDALRFALASVLPEQNDTEISDADIIRRVNDELIANWGNLVNRVLAQINKFFD
HHHHHHCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GELPETGELDGVHAALLDSVDAGLVRVGELLGKVEQRAALRAAMEISAEVNAYLYREEPW
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCC
KTVKVDRAAAARSLAVSIQAISGITTALAPFLPFSSDRVAEVLGIDLDGWERRPVPAGRR
CEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCCCCCCCCCCCCE
LAWSGGLFTKLDVGALDKASLDADA
EEECCCCEEEECCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA