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The map label for this gene is rmlD [H]

Identifier: 158317641

GI number: 158317641

Start: 7164926

End: 7165891

Strand: Reverse

Name: rmlD [H]

Synonym: Franean1_5899

Alternate gene names: 158317641

Gene position: 7165891-7164926 (Counterclockwise)

Preceding gene: 158317643

Following gene: 158317640

Centisome position: 79.78

GC content: 73.71

Gene sequence:

>966_bases
ATGGCGACGTCACTGTCGGGGTGTCGCCGGCTGTTCGTATACGTCTGCCAGACTCGCGGGGTGCGCATCCTCGTCACTGG
TGCCGGTGGACAGCTCGGTAGCGACCTGTGTCGTCTCCTCGACGCTCAGTCGCAGGTTGACAACCCGCGAGTACGGGCCT
GGTGCGGGCTCGCCCGATCCGAACTCGACCTCGCCGACGCGGCCCAGGTGCGTGCGGTCATCGCTGACCAGGCCCGGCCG
GCGAAGATCCAGGGCGGGCTCGCCGTGATCAACACCGCCGCCTGGACGAACGTGGACGGCGCCGAGTCGGACGAGGCGGG
CGCGTACGCCGTGAACGCCACCGGCGCGGCCCATCTGGCCGCCGCGTGCGCCCAGGCCGGTGCGGCGCTCGTCCACCTTT
CCACCGACTACGTCTTCGACGGTGACGCGACCAAGCCCTACGAGACGGACGACCCGCCGGCGCCGGTGTCGGTGTACGGC
CGGACGAAGCTCGCGGGGGAGGAGGCCGTCCTGGCACTCTGCCCGGAGTCGTACGTCGTGCGGACGGCGTGGGTGTACGG
GCGTACCGGCGGCAACTTCGTGAAGACGATCGCCCGGCTGGCCCGGGAGCGCGACGAGCTCGCCGTCGTCGCGGACCAGC
ACGGCAGCCCGACCTGGTCGGTCGACCTCGCCGCCGGCCTGCTCGACCTGGTCACCGCGCGCCCGGCGCCCGGGGTGTAC
CACTGCACCGCGGCCGGGGAGACGACCTGGTACGGCTTCGCCCGCGCGATCGTCGCCGCGCTCGGCCAGGACCCGGCGAA
GGTCAGGCCGACGACGACGGAGGAGTTCCCCCGCCCGGCGCGCCGGCCGGCCTACTCGGTGCTCTCGGCCCGGTCCTGGC
TGGACGCCGGCCTGCGGCCGCTGCGCTCCTGGGACGACGGCTTCGCCGCCGCGTTCGCCGAGTTCGGCGCCGAGCTGCGG
GGCTGA

Upstream 100 bases:

>100_bases
CAGGTCGGGCTTTTCGGTCATTGGCGTCTCGGGCGTCACCGGGATCAGGGTAGCCGCACCCTTCTCGGGCCGGCCGGTGC
CGTCCGGCCGACTGCGCGTG

Downstream 100 bases:

>100_bases
CACCGGCACGGCCACTGCCACTGCCACGGGCCGCCCGGCCCTCGACCAAGCCGGGCACTCGTCGCCGGTGCCGATCTCGG
CTGACGTCCAGCGGGTAGCT

Product: dTDP-4-dehydrorhamnose reductase

Products: NA

Alternate protein names: dTDP-4-keto-L-rhamnose reductase; dTDP-6-deoxy-L-lyxo-4-hexulose reductase; dTDP-6-deoxy-L-mannose dehydrogenase; dTDP-L-rhamnose synthase [H]

Number of amino acids: Translated: 321; Mature: 320

Protein sequence:

>321_residues
MATSLSGCRRLFVYVCQTRGVRILVTGAGGQLGSDLCRLLDAQSQVDNPRVRAWCGLARSELDLADAAQVRAVIADQARP
AKIQGGLAVINTAAWTNVDGAESDEAGAYAVNATGAAHLAAACAQAGAALVHLSTDYVFDGDATKPYETDDPPAPVSVYG
RTKLAGEEAVLALCPESYVVRTAWVYGRTGGNFVKTIARLARERDELAVVADQHGSPTWSVDLAAGLLDLVTARPAPGVY
HCTAAGETTWYGFARAIVAALGQDPAKVRPTTTEEFPRPARRPAYSVLSARSWLDAGLRPLRSWDDGFAAAFAEFGAELR
G

Sequences:

>Translated_321_residues
MATSLSGCRRLFVYVCQTRGVRILVTGAGGQLGSDLCRLLDAQSQVDNPRVRAWCGLARSELDLADAAQVRAVIADQARP
AKIQGGLAVINTAAWTNVDGAESDEAGAYAVNATGAAHLAAACAQAGAALVHLSTDYVFDGDATKPYETDDPPAPVSVYG
RTKLAGEEAVLALCPESYVVRTAWVYGRTGGNFVKTIARLARERDELAVVADQHGSPTWSVDLAAGLLDLVTARPAPGVY
HCTAAGETTWYGFARAIVAALGQDPAKVRPTTTEEFPRPARRPAYSVLSARSWLDAGLRPLRSWDDGFAAAFAEFGAELR
G
>Mature_320_residues
ATSLSGCRRLFVYVCQTRGVRILVTGAGGQLGSDLCRLLDAQSQVDNPRVRAWCGLARSELDLADAAQVRAVIADQARPA
KIQGGLAVINTAAWTNVDGAESDEAGAYAVNATGAAHLAAACAQAGAALVHLSTDYVFDGDATKPYETDDPPAPVSVYGR
TKLAGEEAVLALCPESYVVRTAWVYGRTGGNFVKTIARLARERDELAVVADQHGSPTWSVDLAAGLLDLVTARPAPGVYH
CTAAGETTWYGFARAIVAALGQDPAKVRPTTTEEFPRPARRPAYSVLSARSWLDAGLRPLRSWDDGFAAAFAEFGAELRG

Specific function: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose. Involved in the biosynthesis of the dTDP-L-rhamnose which is a component of the critical linker, D-N-acetylglucosamine-L-rhamnose disaccharide, which connects the galacta

COG id: COG1091

COG function: function code M; dTDP-4-dehydrorhamnose reductase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dTDP-4-dehydrorhamnose reductase family [H]

Homologues:

Organism=Homo sapiens, GI11034825, Length=278, Percent_Identity=29.8561151079137, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI33519455, Length=268, Percent_Identity=30.2238805970149, Blast_Score=91, Evalue=2e-18,
Organism=Escherichia coli, GI1788352, Length=306, Percent_Identity=35.2941176470588, Blast_Score=162, Evalue=3e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005913
- InterPro:   IPR016040 [H]

Pfam domain/function: PF04321 RmlD_sub_bind [H]

EC number: =1.1.1.133 [H]

Molecular weight: Translated: 33878; Mature: 33747

Theoretical pI: Translated: 5.74; Mature: 5.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
0.3 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATSLSGCRRLFVYVCQTRGVRILVTGAGGQLGSDLCRLLDAQSQVDNPRVRAWCGLARS
CCCCHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
ELDLADAAQVRAVIADQARPAKIQGGLAVINTAAWTNVDGAESDEAGAYAVNATGAAHLA
HCCHHHHHHHHHHHHCCCCCCEECCCEEEEEEHHCCCCCCCCCCCCCEEEEECCCHHHHH
AACAQAGAALVHLSTDYVFDGDATKPYETDDPPAPVSVYGRTKLAGEEAVLALCPESYVV
HHHHHCCCEEEEEEECEEECCCCCCCCCCCCCCCCEEECCCCCCCCCCEEEEECCCCCEE
RTAWVYGRTGGNFVKTIARLARERDELAVVADQHGSPTWSVDLAAGLLDLVTARPAPGVY
EEEEEEECCCCHHHHHHHHHHHCCCCEEEEECCCCCCCEEHHHHHHHHHHHHCCCCCCEE
HCTAAGETTWYGFARAIVAALGQDPAKVRPTTTEEFPRPARRPAYSVLSARSWLDAGLRP
EEECCCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHCCCCCCCHHHHHHHHHHHHHHCCHH
LRSWDDGFAAAFAEFGAELRG
HHCCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
ATSLSGCRRLFVYVCQTRGVRILVTGAGGQLGSDLCRLLDAQSQVDNPRVRAWCGLARS
CCCHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
ELDLADAAQVRAVIADQARPAKIQGGLAVINTAAWTNVDGAESDEAGAYAVNATGAAHLA
HCCHHHHHHHHHHHHCCCCCCEECCCEEEEEEHHCCCCCCCCCCCCCEEEEECCCHHHHH
AACAQAGAALVHLSTDYVFDGDATKPYETDDPPAPVSVYGRTKLAGEEAVLALCPESYVV
HHHHHCCCEEEEEEECEEECCCCCCCCCCCCCCCCEEECCCCCCCCCCEEEEECCCCCEE
RTAWVYGRTGGNFVKTIARLARERDELAVVADQHGSPTWSVDLAAGLLDLVTARPAPGVY
EEEEEEECCCCHHHHHHHHHHHCCCCEEEEECCCCCCCEEHHHHHHHHHHHHCCCCCCEE
HCTAAGETTWYGFARAIVAALGQDPAKVRPTTTEEFPRPARRPAYSVLSARSWLDAGLRP
EEECCCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHCCCCCCCHHHHHHHHHHHHHHCCHH
LRSWDDGFAAAFAEFGAELRG
HHCCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA