Click here to switch to the map view.

The map label for this gene is emrY [C]

Identifier: 158317457

GI number: 158317457

Start: 6926442

End: 6928178

Strand: Direct

Name: emrY [C]

Synonym: Franean1_5709

Alternate gene names: 158317457

Gene position: 6926442-6928178 (Clockwise)

Preceding gene: 158317456

Following gene: 158317458

Centisome position: 77.11

GC content: 70.93

Gene sequence:

>1737_bases
ATGACGCCGCCCCCCGGCTTGCCGCCGGGCGGCCAACCGCACGCCGTGACCCGCGCACCGGGATCGGACCATGACTCAGC
CGAGGAGCGGCGCCAGCGCCGGGCCAGCCCGGCAGGCCTGACCCACCGCGAGACCATGCGGGCCCTCTCCGGCCTGCTGC
TGGCCCTGTTCGTATCGATGATCTCCTCCACCATCGTGACGAACGCGCTGCCCAGGATCGTCTCCGACCTGCACGGCAGC
TCGACCAGCTACACCTGGATGATCACGGCGACGCTGCTGGCGATGACCGCCACCACGCCGATCTGGGGCAAGCTGGCGGA
CCTGTTCAACCGTAAGGTGCTGGTCCAGACGGCCCTCGGGATCTTCGTGGGCGGATCCCTCCTGGCCGGGCTGTCGACGT
CCACGAGCATGCTCATCGCGTTCCGCGTGGTGCAGGGCGTCGGCGTCGGCGGGCTGTCGGCGCTGGTCCAGATCGCGATA
GCCGCGATGATCGCGCCGCGTGAACGCGGGCGCTACAACGGCTACCTGGGCGCGACCTTCGCCGTGTCGACCGTCAGCGG
CCCGCTCATCGGCGGCGTGATCGTCGACATCCCGGGCCTGGGCTGGCGCGGCTGCTTCTACCTGAGCCTGCCGATTGCCA
TTGTCGCGTTCGTCATTCTCCAGCGGACGCTGCAGCTGCCCACGGTGCGCCGCGAGATTTCCATCGACTACGCGGGCGCG
ACCCTGATCGCCGCCGGCGTGAGCGCCCTGCTGATCTGGACGTCGCTGGCGGGGTCGAGCTTCCCGTGGGCGTCCGCGCA
GACAGCACTGCTGCTCGGCGGGGGGCTGACGCTACTCGCCGTGGCCGTCTGGGTCGAGGCGCGCGCCACCGAGCCGATCG
TCCCGCTGCGGCTGTTCCGTAACCGGACGATCGTGCTGGCCGTGGCCGCGAGCGCCTGCCTCGGCACCGTCATGTACAGC
GCGAATCTGTTGTTCAGCCAGTACTTCCAGCTCGGCCGCGGGGAGAGCCCGGTGCTGTCGGGGCTGCTCACGGTGCCGAT
GGTGGGCGGCCTGGCCGTCTCGTCTCTGGTGGTGGGAGGTGCCATCAGCCGCACCGGCTACTGGAAGCGCTACCTGATCG
CCGGCACGATCCTGATCGGGACGGGCCTCGTCCTGCTGAGCACAATCAGCGAGCACACGAACCTCGTCGCGGTGTCGGTG
TTCGCGAGCCTGGTGGGAGCCGGACTGGGCATGACCCAGCAGAACCTGGTGCTCGCCGCGCAGAACTCCGCCGACGCCGC
CGATCTCGGGGTGACCAGCTCCACCGTGGCGTTCTTCCGCAGCGTCGGCGGGACGAGCGGCGTCGCGGCACTCGGCGCGC
TACTCGCCCATCGCGTCAGCGTGTCGTCCGTCTCCGGACTGCGCTCGCACGGCCTGCCAGCCGACACTCTTGGGGACGGC
CGCTCCGTGCCCGATCCCACAGCGCTGCCCGGCCCGGTCGCCGACGTCGTGCACCACGCGTACGGGCTCGGAGTGTCCGA
CGTGTTCCTCGCCAGCGCGCCACTCGCGCTGCTCGCGCTGGTAGCGGTGCTGTTCGTGCCGGCCACACGGCTGCGTTCCA
GCGCGGGGGTTGCGGGCGGCGAGCGTGTAACGCCCGAGCGCGCCCACCCCGGAGGGGCCGTGACGGACCTCGACGAGGAT
GTGGAACGGACCGCGTGGCGGGCAGCCGCCGGTGTCTCGGCCGAACCTGCACCATAA

Upstream 100 bases:

>100_bases
ACTCCCCAGCACCCCTCACCCCATGCTTTACTAAAACTTAGTTGTAACAACCAATCAACAGGCGAACCAGTCAACAGGGG
AGCAGGCCACGTCGACCTCG

Downstream 100 bases:

>100_bases
TCAAGGGGTGACACGCAGCCGTCGGCCCGAACAGACGGCCGATACCCGACAGGCACTGCTGGCCGCGGCAAGGCGCCGGT
TCGCCGAACAGGGCTATGCC

Product: major facilitator transporter

Products: Proton [Cytoplasm]; multidrug [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 578; Mature: 577

Protein sequence:

>578_residues
MTPPPGLPPGGQPHAVTRAPGSDHDSAEERRQRRASPAGLTHRETMRALSGLLLALFVSMISSTIVTNALPRIVSDLHGS
STSYTWMITATLLAMTATTPIWGKLADLFNRKVLVQTALGIFVGGSLLAGLSTSTSMLIAFRVVQGVGVGGLSALVQIAI
AAMIAPRERGRYNGYLGATFAVSTVSGPLIGGVIVDIPGLGWRGCFYLSLPIAIVAFVILQRTLQLPTVRREISIDYAGA
TLIAAGVSALLIWTSLAGSSFPWASAQTALLLGGGLTLLAVAVWVEARATEPIVPLRLFRNRTIVLAVAASACLGTVMYS
ANLLFSQYFQLGRGESPVLSGLLTVPMVGGLAVSSLVVGGAISRTGYWKRYLIAGTILIGTGLVLLSTISEHTNLVAVSV
FASLVGAGLGMTQQNLVLAAQNSADAADLGVTSSTVAFFRSVGGTSGVAALGALLAHRVSVSSVSGLRSHGLPADTLGDG
RSVPDPTALPGPVADVVHHAYGLGVSDVFLASAPLALLALVAVLFVPATRLRSSAGVAGGERVTPERAHPGGAVTDLDED
VERTAWRAAAGVSAEPAP

Sequences:

>Translated_578_residues
MTPPPGLPPGGQPHAVTRAPGSDHDSAEERRQRRASPAGLTHRETMRALSGLLLALFVSMISSTIVTNALPRIVSDLHGS
STSYTWMITATLLAMTATTPIWGKLADLFNRKVLVQTALGIFVGGSLLAGLSTSTSMLIAFRVVQGVGVGGLSALVQIAI
AAMIAPRERGRYNGYLGATFAVSTVSGPLIGGVIVDIPGLGWRGCFYLSLPIAIVAFVILQRTLQLPTVRREISIDYAGA
TLIAAGVSALLIWTSLAGSSFPWASAQTALLLGGGLTLLAVAVWVEARATEPIVPLRLFRNRTIVLAVAASACLGTVMYS
ANLLFSQYFQLGRGESPVLSGLLTVPMVGGLAVSSLVVGGAISRTGYWKRYLIAGTILIGTGLVLLSTISEHTNLVAVSV
FASLVGAGLGMTQQNLVLAAQNSADAADLGVTSSTVAFFRSVGGTSGVAALGALLAHRVSVSSVSGLRSHGLPADTLGDG
RSVPDPTALPGPVADVVHHAYGLGVSDVFLASAPLALLALVAVLFVPATRLRSSAGVAGGERVTPERAHPGGAVTDLDED
VERTAWRAAAGVSAEPAP
>Mature_577_residues
TPPPGLPPGGQPHAVTRAPGSDHDSAEERRQRRASPAGLTHRETMRALSGLLLALFVSMISSTIVTNALPRIVSDLHGSS
TSYTWMITATLLAMTATTPIWGKLADLFNRKVLVQTALGIFVGGSLLAGLSTSTSMLIAFRVVQGVGVGGLSALVQIAIA
AMIAPRERGRYNGYLGATFAVSTVSGPLIGGVIVDIPGLGWRGCFYLSLPIAIVAFVILQRTLQLPTVRREISIDYAGAT
LIAAGVSALLIWTSLAGSSFPWASAQTALLLGGGLTLLAVAVWVEARATEPIVPLRLFRNRTIVLAVAASACLGTVMYSA
NLLFSQYFQLGRGESPVLSGLLTVPMVGGLAVSSLVVGGAISRTGYWKRYLIAGTILIGTGLVLLSTISEHTNLVAVSVF
ASLVGAGLGMTQQNLVLAAQNSADAADLGVTSSTVAFFRSVGGTSGVAALGALLAHRVSVSSVSGLRSHGLPADTLGDGR
SVPDPTALPGPVADVVHHAYGLGVSDVFLASAPLALLALVAVLFVPATRLRSSAGVAGGERVTPERAHPGGAVTDLDEDV
ERTAWRAAAGVSAEPAP

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. TCR/tet family [H]

Homologues:

Organism=Escherichia coli, GI1788710, Length=435, Percent_Identity=25.9770114942529, Blast_Score=99, Evalue=1e-21,
Organism=Escherichia coli, GI1789042, Length=301, Percent_Identity=29.9003322259136, Blast_Score=94, Evalue=3e-20,
Organism=Escherichia coli, GI87081983, Length=430, Percent_Identity=26.7441860465116, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI1790195, Length=399, Percent_Identity=26.5664160401003, Blast_Score=86, Evalue=6e-18,
Organism=Escherichia coli, GI1788392, Length=334, Percent_Identity=28.4431137724551, Blast_Score=70, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6322958, Length=538, Percent_Identity=26.5799256505576, Blast_Score=119, Evalue=1e-27,
Organism=Saccharomyces cerevisiae, GI6323735, Length=331, Percent_Identity=29.0030211480363, Blast_Score=105, Evalue=2e-23,
Organism=Saccharomyces cerevisiae, GI6325455, Length=515, Percent_Identity=23.8834951456311, Blast_Score=95, Evalue=3e-20,
Organism=Saccharomyces cerevisiae, GI6319770, Length=382, Percent_Identity=26.4397905759162, Blast_Score=89, Evalue=2e-18,
Organism=Saccharomyces cerevisiae, GI6321663, Length=547, Percent_Identity=23.217550274223, Blast_Score=86, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR005829
- InterPro:   IPR001958
- InterPro:   IPR011991 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 59306; Mature: 59174

Theoretical pI: Translated: 9.88; Mature: 9.88

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPPPGLPPGGQPHAVTRAPGSDHDSAEERRQRRASPAGLTHRETMRALSGLLLALFVSM
CCCCCCCCCCCCCCCEEECCCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHH
ISSTIVTNALPRIVSDLHGSSTSYTWMITATLLAMTATTPIWGKLADLFNRKVLVQTALG
HHHHHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHCCCHHHHHHHHHCCHHHHHHHHH
IFVGGSLLAGLSTSTSMLIAFRVVQGVGVGGLSALVQIAIAAMIAPRERGRYNGYLGATF
HHHHHHHHHCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCHHHCCCCCCEECHHE
AVSTVSGPLIGGVIVDIPGLGWRGCFYLSLPIAIVAFVILQRTLQLPTVRREISIDYAGA
EEHHCCCCHHCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHEEECCCH
TLIAAGVSALLIWTSLAGSSFPWASAQTALLLGGGLTLLAVAVWVEARATEPIVPLRLFR
HHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHCCCCCCHHHHHHC
NRTIVLAVAASACLGTVMYSANLLFSQYFQLGRGESPVLSGLLTVPMVGGLAVSSLVVGG
CCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCC
AISRTGYWKRYLIAGTILIGTGLVLLSTISEHTNLVAVSVFASLVGAGLGMTQQNLVLAA
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCEEEEE
QNSADAADLGVTSSTVAFFRSVGGTSGVAALGALLAHRVSVSSVSGLRSHGLPADTLGDG
CCCCCHHHCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
RSVPDPTALPGPVADVVHHAYGLGVSDVFLASAPLALLALVAVLFVPATRLRSSAGVAGG
CCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHCCCCCC
ERVTPERAHPGGAVTDLDEDVERTAWRAAAGVSAEPAP
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
TPPPGLPPGGQPHAVTRAPGSDHDSAEERRQRRASPAGLTHRETMRALSGLLLALFVSM
CCCCCCCCCCCCCCEEECCCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHH
ISSTIVTNALPRIVSDLHGSSTSYTWMITATLLAMTATTPIWGKLADLFNRKVLVQTALG
HHHHHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHCCCHHHHHHHHHCCHHHHHHHHH
IFVGGSLLAGLSTSTSMLIAFRVVQGVGVGGLSALVQIAIAAMIAPRERGRYNGYLGATF
HHHHHHHHHCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCHHHCCCCCCEECHHE
AVSTVSGPLIGGVIVDIPGLGWRGCFYLSLPIAIVAFVILQRTLQLPTVRREISIDYAGA
EEHHCCCCHHCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHEEECCCH
TLIAAGVSALLIWTSLAGSSFPWASAQTALLLGGGLTLLAVAVWVEARATEPIVPLRLFR
HHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHCCCCCCHHHHHHC
NRTIVLAVAASACLGTVMYSANLLFSQYFQLGRGESPVLSGLLTVPMVGGLAVSSLVVGG
CCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCC
AISRTGYWKRYLIAGTILIGTGLVLLSTISEHTNLVAVSVFASLVGAGLGMTQQNLVLAA
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCEEEEE
QNSADAADLGVTSSTVAFFRSVGGTSGVAALGALLAHRVSVSSVSGLRSHGLPADTLGDG
CCCCCHHHCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
RSVPDPTALPGPVADVVHHAYGLGVSDVFLASAPLALLALVAVLFVPATRLRSSAGVAGG
CCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHCCCCCC
ERVTPERAHPGGAVTDLDEDVERTAWRAAAGVSAEPAP
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; multidrug [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + multidrug [Cytoplasm] = Proton [Cytoplasm] + multidrug [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]