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The map label for this gene is hapE [H]

Identifier: 158316517

GI number: 158316517

Start: 5673777

End: 5675582

Strand: Reverse

Name: hapE [H]

Synonym: Franean1_4752

Alternate gene names: 158316517

Gene position: 5675582-5673777 (Counterclockwise)

Preceding gene: 158316518

Following gene: 158316516

Centisome position: 63.19

GC content: 69.05

Gene sequence:

>1806_bases
ATGAGCGAGACAGTGACCGAGACTTTAGAGAGCCCGGCCGAGGCGATCACCGCGCGGGACGCCGAGGACATCTTCGCCGG
ATGGCTCGCCGACTTCGCGGCGGCCCTGCGGAGCGGATCCACGTCCGACCTCGCCGCGCTCTTCCTCCCGGAGGCGACCT
GGCGTGACTTCATGGCCTTCCCCTGGGACTTCCACCACACGGTCGGGCGGGAGGAGACCGTCGCCCGGCTCACCGAGCTG
GCGAAGGCCTGGAACGCCGCCGACTTCCGGCCCAGCCGGGAGCAGCCGCCGGTCGTCACGGACGGCGCCATCAACGCGTT
CTTCGACTTCACCACCACGGACCGGATCGACCGTGGCTATGTGCTGCTCGTACCGAGCGCGGGGCATTTCGTGGTGTCGA
TCCTGCAGACCCAGGTGATAGGGCTGCAGGCCCATCCGGAACGGGTGCGTCACCATCGCCGGGACGGCAAGGTCTACGGG
ATCGTGCCCGACCGCACCCGGTGGTCGAGCGACCGCGAGAAGGAGATCGCCTTCGAGGACGGCGAGCCCGCGGTGCTCGT
GCTCGGCGCGGGGCACAACGGGCTGGCCATAGCGGCCCGGCTCGGCGCGCTCGACGTGCCGACGCTCGTCATCGACCGCG
AGGCGCGGGTCGGGGACACCTGGCGCAAGCGCTACGCGTCGCTGGCCCTGCACAGCACCGTCTTCGGGGACCATCTGCCC
TACCTGTCGCTGCCGCCCTCCTGGCCGGCGCACACCCCGAAGGACAAGTTCGCCGACTGGCTGGAGTCGTACGCGAACCT
GCTCGACCTCAACGTGTGGACGTCCACCACGTTCCTCGACGGGCACTTCGACGAGGACGCCCAGCGGTGGACGATCCGGG
TCCGGCGCGGGGACGGCTCGGTCCGGGAGCTGCACCCGCGGCACTTCGTCGTGGCGGGCGGCCTGTTCGGATCGCCGAAG
ATTCCCGCGATCAAGGGCCTCGAGACCTTCCCCGGCATGACGGCGCACTCGGACGAGTTCCAGTACGGCGCCGACTTCCA
GGGCAGGAGGGCGCTGGTGATCGGGGCCGGTGTTAGCGGCCACGAGATCGCGCACGACCTGTACGAGCACGGCGCGGACG
TCACGATGCTGCAGCGCAGTGCCACCTACGTGGTGAACTACACGTCCTACCACCGGTACTGGTCGACGCTGTTCACCGAG
GACATGCCCTACACCCCGGACTTCGCGGACCAGATGACCTACGCGCTGCCCAACGAGCGGGTCGACGAGCTCAACAAGAA
GCTGGTGAAGCTCGCTGCGGCGGCCGACCAGGATCTGCTCGACGGTCTCACCTCGCGGGGCTTCAAGCTCGAGTGGGGCC
CGGACGGCACCGGCATCATCGGCGCCCACATGTCCGGCAAGGACGCCTACCAGATCAACATCGGCGCGTCCGAACTGATC
GCGGACGGCCTGGTGCACCTCAAGCAGGGCGTCGAGGTGGCCGAGATCAGGGAGCGGACGGTGGTCTTCACCGACGGCTC
GACCCTCGACGTCGACCTGATCGTCTTCGCCACCGGCTACCACCAGTTCTGGGGCCACATCAAGCCGACGCTGGGCTCGG
CGGCGGACCGGATCGACAAGGCGTACGGCCGGGCCGCGGACGGCGAGTACGCGAACACGTGGCGTCGCTCCGCCCAGCCC
GGGCTGTGGTTCGGCACCGGGTTCATCCGGATGGCCCGCTTCTACACCCGGTTCACGGCGCTGCTGATCAAGGCGATCGA
GGTCGGTGTCGAGCCGATGAACCCGGACCGGGCCGACGGCAACTGA

Upstream 100 bases:

>100_bases
CGCGGCGGCGCGCGACCCGGCGTCCGGCGCCCGGTCGCCGGTCCTGAGTGAACGATCCGGAAGCTGACCCGAAGCCAGTA
GATCATCGGGAGTTGGGGCG

Downstream 100 bases:

>100_bases
TGGCCGCCATCGACGTGCACAAACGGGTCGAGCCCGGGACCGTGGCGCTGCTCGATCGGCTGGCGCGCTGGGACCTGACG
AGCATCGCGACGATCCGGCG

Product: putative dimethylaniline monooxygenase

Products: NA

Alternate protein names: HAPMO; Baeyer-Villiger monooxygenase; BVMO [H]

Number of amino acids: Translated: 601; Mature: 600

Protein sequence:

>601_residues
MSETVTETLESPAEAITARDAEDIFAGWLADFAAALRSGSTSDLAALFLPEATWRDFMAFPWDFHHTVGREETVARLTEL
AKAWNAADFRPSREQPPVVTDGAINAFFDFTTTDRIDRGYVLLVPSAGHFVVSILQTQVIGLQAHPERVRHHRRDGKVYG
IVPDRTRWSSDREKEIAFEDGEPAVLVLGAGHNGLAIAARLGALDVPTLVIDREARVGDTWRKRYASLALHSTVFGDHLP
YLSLPPSWPAHTPKDKFADWLESYANLLDLNVWTSTTFLDGHFDEDAQRWTIRVRRGDGSVRELHPRHFVVAGGLFGSPK
IPAIKGLETFPGMTAHSDEFQYGADFQGRRALVIGAGVSGHEIAHDLYEHGADVTMLQRSATYVVNYTSYHRYWSTLFTE
DMPYTPDFADQMTYALPNERVDELNKKLVKLAAAADQDLLDGLTSRGFKLEWGPDGTGIIGAHMSGKDAYQINIGASELI
ADGLVHLKQGVEVAEIRERTVVFTDGSTLDVDLIVFATGYHQFWGHIKPTLGSAADRIDKAYGRAADGEYANTWRRSAQP
GLWFGTGFIRMARFYTRFTALLIKAIEVGVEPMNPDRADGN

Sequences:

>Translated_601_residues
MSETVTETLESPAEAITARDAEDIFAGWLADFAAALRSGSTSDLAALFLPEATWRDFMAFPWDFHHTVGREETVARLTEL
AKAWNAADFRPSREQPPVVTDGAINAFFDFTTTDRIDRGYVLLVPSAGHFVVSILQTQVIGLQAHPERVRHHRRDGKVYG
IVPDRTRWSSDREKEIAFEDGEPAVLVLGAGHNGLAIAARLGALDVPTLVIDREARVGDTWRKRYASLALHSTVFGDHLP
YLSLPPSWPAHTPKDKFADWLESYANLLDLNVWTSTTFLDGHFDEDAQRWTIRVRRGDGSVRELHPRHFVVAGGLFGSPK
IPAIKGLETFPGMTAHSDEFQYGADFQGRRALVIGAGVSGHEIAHDLYEHGADVTMLQRSATYVVNYTSYHRYWSTLFTE
DMPYTPDFADQMTYALPNERVDELNKKLVKLAAAADQDLLDGLTSRGFKLEWGPDGTGIIGAHMSGKDAYQINIGASELI
ADGLVHLKQGVEVAEIRERTVVFTDGSTLDVDLIVFATGYHQFWGHIKPTLGSAADRIDKAYGRAADGEYANTWRRSAQP
GLWFGTGFIRMARFYTRFTALLIKAIEVGVEPMNPDRADGN
>Mature_600_residues
SETVTETLESPAEAITARDAEDIFAGWLADFAAALRSGSTSDLAALFLPEATWRDFMAFPWDFHHTVGREETVARLTELA
KAWNAADFRPSREQPPVVTDGAINAFFDFTTTDRIDRGYVLLVPSAGHFVVSILQTQVIGLQAHPERVRHHRRDGKVYGI
VPDRTRWSSDREKEIAFEDGEPAVLVLGAGHNGLAIAARLGALDVPTLVIDREARVGDTWRKRYASLALHSTVFGDHLPY
LSLPPSWPAHTPKDKFADWLESYANLLDLNVWTSTTFLDGHFDEDAQRWTIRVRRGDGSVRELHPRHFVVAGGLFGSPKI
PAIKGLETFPGMTAHSDEFQYGADFQGRRALVIGAGVSGHEIAHDLYEHGADVTMLQRSATYVVNYTSYHRYWSTLFTED
MPYTPDFADQMTYALPNERVDELNKKLVKLAAAADQDLLDGLTSRGFKLEWGPDGTGIIGAHMSGKDAYQINIGASELIA
DGLVHLKQGVEVAEIRERTVVFTDGSTLDVDLIVFATGYHQFWGHIKPTLGSAADRIDKAYGRAADGEYANTWRRSAQPG
LWFGTGFIRMARFYTRFTALLIKAIEVGVEPMNPDRADGN

Specific function: Catalyzes a Baeyer-Villiger oxidation reaction, i.e., the insertion of an oxygen atom into a carbon-carbon bond adjacent to a carbonyl, which converts ketones to esters. Can oxidize a wide range of acetophenone derivatives. Highest activity occurs with co

COG id: COG2072

COG function: function code P; Predicted flavoprotein involved in K+ transport

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAD-binding monooxygenase family [H]

Homologues:

Organism=Homo sapiens, GI4503759, Length=358, Percent_Identity=25.4189944134078, Blast_Score=79, Evalue=9e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR020946 [H]

Pfam domain/function: PF00743 FMO-like [H]

EC number: =1.14.13.84 [H]

Molecular weight: Translated: 66721; Mature: 66590

Theoretical pI: Translated: 5.55; Mature: 5.55

Prosite motif: PS00142 ZINC_PROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSETVTETLESPAEAITARDAEDIFAGWLADFAAALRSGSTSDLAALFLPEATWRDFMAF
CCCHHHHHHHCHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHCC
PWDFHHTVGREETVARLTELAKAWNAADFRPSREQPPVVTDGAINAFFDFTTTDRIDRGY
CCCHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCEEECCCCEEEEECCCCCCCCCCE
VLLVPSAGHFVVSILQTQVIGLQAHPERVRHHRRDGKVYGIVPDRTRWSSDREKEIAFED
EEEECCCCHHHHHHHHHHHHCCCCCHHHHHHHCCCCCEEEECCCCCCCCCCCCCCCEEEC
GEPAVLVLGAGHNGLAIAARLGALDVPTLVIDREARVGDTWRKRYASLALHSTVFGDHLP
CCCEEEEEECCCCCEEEEEECCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCC
YLSLPPSWPAHTPKDKFADWLESYANLLDLNVWTSTTFLDGHFDEDAQRWTIRVRRGDGS
CCCCCCCCCCCCCHHHHHHHHHHHHHHEEEEEEECEEEECCCCCCCCCEEEEEEECCCCC
VRELHPRHFVVAGGLFGSPKIPAIKGLETFPGMTAHSDEFQYGADFQGRRALVIGAGVSG
HHHCCCCEEEEECCCCCCCCCCCCCCCHHCCCCCCCCCCCCCCCCCCCCEEEEEECCCCH
HEIAHDLYEHGADVTMLQRSATYVVNYTSYHRYWSTLFTEDMPYTPDFADQMTYALPNER
HHHHHHHHHCCCCEEEEECCCEEEEECHHHHHHHHHHHCCCCCCCCCHHHHHHHCCCCHH
VDELNKKLVKLAAAADQDLLDGLTSRGFKLEWGPDGTGIIGAHMSGKDAYQINIGASELI
HHHHHHHHHHHHHHCCHHHHHHHHCCCEEEEECCCCCCEEEEECCCCCEEEEECCHHHHH
ADGLVHLKQGVEVAEIRERTVVFTDGSTLDVDLIVFATGYHQFWGHIKPTLGSAADRIDK
HHHHHHHHHCCCHHHHCCCEEEEECCCEEEEEEEEEECCHHHHHCCCCCHHHHHHHHHHH
AYGRAADGEYANTWRRSAQPGLWFGTGFIRMARFYTRFTALLIKAIEVGVEPMNPDRADG
HHCCCCCCCHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
N
C
>Mature Secondary Structure 
SETVTETLESPAEAITARDAEDIFAGWLADFAAALRSGSTSDLAALFLPEATWRDFMAF
CCHHHHHHHCHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHCC
PWDFHHTVGREETVARLTELAKAWNAADFRPSREQPPVVTDGAINAFFDFTTTDRIDRGY
CCCHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCEEECCCCEEEEECCCCCCCCCCE
VLLVPSAGHFVVSILQTQVIGLQAHPERVRHHRRDGKVYGIVPDRTRWSSDREKEIAFED
EEEECCCCHHHHHHHHHHHHCCCCCHHHHHHHCCCCCEEEECCCCCCCCCCCCCCCEEEC
GEPAVLVLGAGHNGLAIAARLGALDVPTLVIDREARVGDTWRKRYASLALHSTVFGDHLP
CCCEEEEEECCCCCEEEEEECCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCC
YLSLPPSWPAHTPKDKFADWLESYANLLDLNVWTSTTFLDGHFDEDAQRWTIRVRRGDGS
CCCCCCCCCCCCCHHHHHHHHHHHHHHEEEEEEECEEEECCCCCCCCCEEEEEEECCCCC
VRELHPRHFVVAGGLFGSPKIPAIKGLETFPGMTAHSDEFQYGADFQGRRALVIGAGVSG
HHHCCCCEEEEECCCCCCCCCCCCCCCHHCCCCCCCCCCCCCCCCCCCCEEEEEECCCCH
HEIAHDLYEHGADVTMLQRSATYVVNYTSYHRYWSTLFTEDMPYTPDFADQMTYALPNER
HHHHHHHHHCCCCEEEEECCCEEEEECHHHHHHHHHHHCCCCCCCCCHHHHHHHCCCCHH
VDELNKKLVKLAAAADQDLLDGLTSRGFKLEWGPDGTGIIGAHMSGKDAYQINIGASELI
HHHHHHHHHHHHHHCCHHHHHHHHCCCEEEEECCCCCCEEEEECCCCCEEEEECCHHHHH
ADGLVHLKQGVEVAEIRERTVVFTDGSTLDVDLIVFATGYHQFWGHIKPTLGSAADRIDK
HHHHHHHHHCCCHHHHCCCEEEEECCCEEEEEEEEEECCHHHHHCCCCCHHHHHHHHHHH
AYGRAADGEYANTWRRSAQPGLWFGTGFIRMARFYTRFTALLIKAIEVGVEPMNPDRADG
HHCCCCCCCHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
N
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11322873 [H]