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The map label for this gene is lip2 [H]

Identifier: 158316516

GI number: 158316516

Start: 5672779

End: 5673777

Strand: Reverse

Name: lip2 [H]

Synonym: Franean1_4751

Alternate gene names: 158316516

Gene position: 5673777-5672779 (Counterclockwise)

Preceding gene: 158316517

Following gene: 158316515

Centisome position: 63.17

GC content: 75.68

Gene sequence:

>999_bases
ATGGCCGCCATCGACGTGCACAAACGGGTCGAGCCCGGGACCGTGGCGCTGCTCGATCGGCTGGCGCGCTGGGACCTGAC
GAGCATCGCGACGATCCGGCGCTCGTACGCGGCGGTCGGCCCGCCGTCCGCCCCCGAGGATCCGCGGGTCCGGCGTCGCG
ACCAGGTCATCCCGGGCACGGACGGCCGTCCCGACGTCCGGGTGCGCTGGTACCGCCCCGCCGACGCCCCCGCCGGGGCG
GCGCTGCCCTTCCTCCTCTGGCTGCACGGCGGCGCCTACATCATGGGGAACCTGGACGAGAACGACGACCGCCTCGACCG
GATGGTCATCGAGCTCGGCTGCGCCGTCGCCTCGGTCGACTGGCGGCTGGCCCCGGAGCACCCCTACCCGGCGGGCCTGG
AGGACGCGGAGACGGTCTGGCGCCGGGTCAGCGCGAACCCGGCCGACTTCGGGGTCGACCCGGCCCGACTGGTCCTGGGC
GGGGCGAGCGCGGGTGCCGGCCTGGCCGCCGGACTGTGCCTGCGGCTGCGGGACCTCGGCGTCCCCCAGCCGGTGCTGCA
GCTGCTGATCTACCCGATGCTCGACGACCGTGAGCTGACACCCTCGATCCGCGCGATCGAGGACCCGGGGCACTGGGGCC
TGTGGCATCTGCGGGCCAACCGGATGTGCTGGGCGGCCTATCTCGGGTCGCTCGACGGCGGCGAGGTCCCGCCCACCGCG
GCGCCGGCGCGGGCGGAGGACCTCACCGGGCTCGCGCCGGCCTTCCTCGGGATCGGCGACGTCGACGGGTTCGTGGACGA
GAACGTCGCCTACGCGGCACGCCTGTCGGCCGCGGGCGTGCCGATCGAGCTGCACGTGTACCCCGGGGTCATCCACGGCG
GGTTCGGCGCACCGCCGCGCACCCCGCGCACCGCGCAGTTCCTGCGGGACGTCTACGCGGCGCTGGCCGCCGCGTTCGTG
CCGGCGGACGGATCCCAGGAAGCCGGCGAGGGGCCCTGA

Upstream 100 bases:

>100_bases
TCCGGATGGCCCGCTTCTACACCCGGTTCACGGCGCTGCTGATCAAGGCGATCGAGGTCGGTGTCGAGCCGATGAACCCG
GACCGGGCCGACGGCAACTG

Downstream 100 bases:

>100_bases
TGGTCGGGGAGAACCTGGCGGACGTGGCGAACCTGGCGGACGTGGCTGGCCTGGCGGAGGTGGAGAGCAGGCTCCGGCGG
CTGGAGGCACGGCTGCGGTC

Product: alpha/beta hydrolase domain-containing protein

Products: NA

Alternate protein names: Triacylglycerol lipase [H]

Number of amino acids: Translated: 332; Mature: 331

Protein sequence:

>332_residues
MAAIDVHKRVEPGTVALLDRLARWDLTSIATIRRSYAAVGPPSAPEDPRVRRRDQVIPGTDGRPDVRVRWYRPADAPAGA
ALPFLLWLHGGAYIMGNLDENDDRLDRMVIELGCAVASVDWRLAPEHPYPAGLEDAETVWRRVSANPADFGVDPARLVLG
GASAGAGLAAGLCLRLRDLGVPQPVLQLLIYPMLDDRELTPSIRAIEDPGHWGLWHLRANRMCWAAYLGSLDGGEVPPTA
APARAEDLTGLAPAFLGIGDVDGFVDENVAYAARLSAAGVPIELHVYPGVIHGGFGAPPRTPRTAQFLRDVYAALAAAFV
PADGSQEAGEGP

Sequences:

>Translated_332_residues
MAAIDVHKRVEPGTVALLDRLARWDLTSIATIRRSYAAVGPPSAPEDPRVRRRDQVIPGTDGRPDVRVRWYRPADAPAGA
ALPFLLWLHGGAYIMGNLDENDDRLDRMVIELGCAVASVDWRLAPEHPYPAGLEDAETVWRRVSANPADFGVDPARLVLG
GASAGAGLAAGLCLRLRDLGVPQPVLQLLIYPMLDDRELTPSIRAIEDPGHWGLWHLRANRMCWAAYLGSLDGGEVPPTA
APARAEDLTGLAPAFLGIGDVDGFVDENVAYAARLSAAGVPIELHVYPGVIHGGFGAPPRTPRTAQFLRDVYAALAAAFV
PADGSQEAGEGP
>Mature_331_residues
AAIDVHKRVEPGTVALLDRLARWDLTSIATIRRSYAAVGPPSAPEDPRVRRRDQVIPGTDGRPDVRVRWYRPADAPAGAA
LPFLLWLHGGAYIMGNLDENDDRLDRMVIELGCAVASVDWRLAPEHPYPAGLEDAETVWRRVSANPADFGVDPARLVLGG
ASAGAGLAAGLCLRLRDLGVPQPVLQLLIYPMLDDRELTPSIRAIEDPGHWGLWHLRANRMCWAAYLGSLDGGEVPPTAA
PARAEDLTGLAPAFLGIGDVDGFVDENVAYAARLSAAGVPIELHVYPGVIHGGFGAPPRTPRTAQFLRDVYAALAAAFVP
ADGSQEAGEGP

Specific function: Has An Esterase Activity. Triacetyl Glycerol (Triacetin) Is A Substrate Of The Enzyme. [C]

COG id: COG0657

COG function: function code I; Esterase/lipase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'GDXG' lipolytic enzyme family [H]

Homologues:

Organism=Homo sapiens, GI157041239, Length=161, Percent_Identity=30.4347826086957, Blast_Score=66, Evalue=6e-11,
Organism=Escherichia coli, GI1786682, Length=266, Percent_Identity=27.0676691729323, Blast_Score=82, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI17567059, Length=273, Percent_Identity=27.8388278388278, Blast_Score=94, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17540028, Length=151, Percent_Identity=30.4635761589404, Blast_Score=75, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI72001146, Length=170, Percent_Identity=31.1764705882353, Blast_Score=75, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI71996133, Length=158, Percent_Identity=29.1139240506329, Blast_Score=74, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013094
- InterPro:   IPR002168 [H]

Pfam domain/function: PF07859 Abhydrolase_3 [H]

EC number: =3.1.1.3 [H]

Molecular weight: Translated: 35468; Mature: 35336

Theoretical pI: Translated: 4.94; Mature: 4.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAAIDVHKRVEPGTVALLDRLARWDLTSIATIRRSYAAVGPPSAPEDPRVRRRDQVIPGT
CCCCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHCCCCCCC
DGRPDVRVRWYRPADAPAGAALPFLLWLHGGAYIMGNLDENDDRLDRMVIELGCAVASVD
CCCCCEEEEEECCCCCCCCHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHHHHHHEECC
WRLAPEHPYPAGLEDAETVWRRVSANPADFGVDPARLVLGGASAGAGLAAGLCLRLRDLG
CEECCCCCCCCCCCHHHHHHHHHCCCCCCCCCCHHHEEEECCCCCHHHHHHHHHHHHHCC
VPQPVLQLLIYPMLDDRELTPSIRAIEDPGHWGLWHLRANRMCWAAYLGSLDGGEVPPTA
CCHHHHHHHHHCCCCCCCCCCCCEEECCCCCCEEEEEECCCEEHHHHHCCCCCCCCCCCC
APARAEDLTGLAPAFLGIGDVDGFVDENVAYAARLSAAGVPIELHVYPGVIHGGFGAPPR
CCCCHHHHCCHHHHHHCCCCCCCHHCCCHHHHHHHHHCCCCEEEEEECCEEECCCCCCCC
TPRTAQFLRDVYAALAAAFVPADGSQEAGEGP
CCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure 
AAIDVHKRVEPGTVALLDRLARWDLTSIATIRRSYAAVGPPSAPEDPRVRRRDQVIPGT
CCCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHCCCCCCC
DGRPDVRVRWYRPADAPAGAALPFLLWLHGGAYIMGNLDENDDRLDRMVIELGCAVASVD
CCCCCEEEEEECCCCCCCCHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHHHHHHEECC
WRLAPEHPYPAGLEDAETVWRRVSANPADFGVDPARLVLGGASAGAGLAAGLCLRLRDLG
CEECCCCCCCCCCCHHHHHHHHHCCCCCCCCCCHHHEEEECCCCCHHHHHHHHHHHHHCC
VPQPVLQLLIYPMLDDRELTPSIRAIEDPGHWGLWHLRANRMCWAAYLGSLDGGEVPPTA
CCHHHHHHHHHCCCCCCCCCCCCEEECCCCCCEEEEEECCCEEHHHHHCCCCCCCCCCCC
APARAEDLTGLAPAFLGIGDVDGFVDENVAYAARLSAAGVPIELHVYPGVIHGGFGAPPR
CCCCHHHHCCHHHHHHCCCCCCCHHCCCHHHHHHHHHCCCCEEEEEECCEEECCCCCCCC
TPRTAQFLRDVYAALAAAFVPADGSQEAGEGP
CCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1907455 [H]