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The map label for this gene is yuxG [H]

Identifier: 158316437

GI number: 158316437

Start: 5579596

End: 5581635

Strand: Reverse

Name: yuxG [H]

Synonym: Franean1_4672

Alternate gene names: 158316437

Gene position: 5581635-5579596 (Counterclockwise)

Preceding gene: 158316438

Following gene: 158316436

Centisome position: 62.14

GC content: 74.07

Gene sequence:

>2040_bases
GTGAGCGGGAACCAGACCGTCGCCGAGCTCCTCGCCCGGTCGAACCGGCTCGGCGCCGACCCGCGCAACACCAACTACGC
GGGCGGCAACACCTCCGCCAAGGGCGTCGAGATCGATCCCGTCACGGGCCGCGACGTCGAGCTGCTGTGGGTCAAGGGGT
CGGGCGGCGACCTCGGCACGCTGACCGAGCCCGGCCTCGCCGTCCTCCGGCTGGACCGGCTGCGCGCGCTCGTGGACGTC
TACCCCGGCGAGGGCCGCGAGGACGAGATGGTCGCCGCCTTCGACTTCTGCCTGCACGGCCGGGGCGGTGCCGCGCCCTC
GATCGACACCGCCATGCACGGGCTCGTCGACGCCTCGCACGTCGACCACCTGCACCCGGACAGCGGCATCGCCCTCGCGA
CCGCCGCCGACGGCGAACAGCTCACGAAGGACGTCTTCGGCACGAAGGTCGCGTGGGTGCCGTGGCGGCGGCCGGGCTTC
CAGCTCGGCCTCGACATCGCGGCCGTGCGGCGGGACAACCCCGGCGCCGTCGGCTGCATCCTCGGCGGGCACGGCATCAC
CGCGTGGGGCGACACGAGCGAGGAGTCCGAGCGCAACTCCACCTGGATCATCGAGCAGGCGCGGCTCCACCTCGAGCGGC
ACGGGCGGCCGCGGCCCTTCGGCGCCGTGGCCGACGGCCGGCGCGCGCTGCCAGCCGGGCAACGGCGGGCCAGGGCCGCC
GTGCTCGCGCCCCACCTGCGTGCGGTCGCGTCCCGCGACCACCGCATGGTCGGCCACTTCACCGACAGCGACGCCGTCCT
GGAGTTCCTGGCCAGCGAGAAGCTGTTCGCCCTGGCCCGGCTCGGGACGTCCTGCCCCGACCACTTCCTGCGGACGAAGG
TCCGCCCGCTGGTGCTCGACCTGCCGGCCGCGGCGTCACCCGAGGAGTGCGTCCGGCGGCTCGCGGAGCTGCACGAGGCC
TACCGCGCCGACTACCGCGCGTACTACGAGCGGCATGCCACCGCCGACTCGCCGCCGATGCGCGGCGCGGACCCGGCGAT
CATCCTCGTGCCGGGCGTGGGCATGTTCTCCTACGGCCGGGACAAACAGACGGCACGGGTGGCCGGCGAGTTCTACGTCA
ACGCGATCAACGTGATGCGCGGTGCCGAGGCGGTCTCGTCCTACGCGCCGATCCCGGAGCGCGAGAAGTTCCGGATCGAG
TACTGGGCGTTGGAGGAGGCGAAGCTGCGCCGCCTACCGCCGCCCAAGCGGCACGCGGGCCGGGTCGCGCTGGTCACCGG
CGCGGCCAGCGGCATCGGCCGGGCCACCGCGTCCCGGCTCGCCGCCGACGGCGCCTGTGTGGTCGTCGCCGACCTCGACG
CGACCAGCGCCGTGTCGGCGGCGGGCGAGCTCGGCGGCGCCGACGTCGCGGTCGGCGTCGGCGCCGACGTGACGAAGGAG
GCCGAGGTCGCGGCCGCCGTCGCGGCGGCACTGCTCGCCTTCGGCGGGATCGACCTCGTCGTCAACAACGCGGGCCTGTC
CATCTCCAAACCGCTGCTGGAGACCACCGAGCGGGACTGGGACCTGCAGCACGACGTCATGGCGAAGGGAAGCTTCCTCG
TCGCGCGGGCCGCGGCGCGAGCCATGATCGACCAACGGCTCGGCGGTGACATCGTCTACATCGTCTCCAAGAACGCGCTG
TTCGCCGGGCCGAACAACGTCGCCTACGGCGCCGCGAAGGCCGACCAGGCGCACCAGGTCAGGCTGCTGGCGGCCGAGCT
CGGCGAGCACGGGATCCGGGTCAACGGCGTCAACCCGGATGGCGTCGTGCGTGGTAGCGGCATCTTCGCCGGCGGGTGGG
GAGCCCAGCGTGCGGCGGTCTACGGCATCCCCGAGGAGGAGCTCGGCGCCTTCTACGCCCGGCGGACGCTGCTCGGCCGG
GAGGTGCTGCCCGAGCACGTGGCCAACGCGGTCGCGGCCGTGTGCTCGACCGAGCTCAGCCACACGACCGGCCTGCTCGT
CCCCGTCGACGCCGGCGTCGCGGCCGCCTTCCTGCGCTGA

Upstream 100 bases:

>100_bases
GCGGGCTGCCCGCCGACCCCCTGGCGGCCTTCCAGTCCAGCGGTTACGCCGAGCGCGTCGCGGCCGAGCGGGTCGGTGGC
ACCCAGGCCGGGTGGGGCGC

Downstream 100 bases:

>100_bases
CGGCGACGCTGTGCTGACTGTGGCGTCCGCGCCGACGATGACGTCGGGCTGCCCATGACCGCCAGGGTGTTCGCCGCCGT
CGACATCGGGGCGTCCGGCG

Product: short chain dehydrogenase

Products: D-Gluconate; Nicotinamide adenine dinucleotide phosphate [C]

Alternate protein names: ORF2 [H]

Number of amino acids: Translated: 679; Mature: 678

Protein sequence:

>679_residues
MSGNQTVAELLARSNRLGADPRNTNYAGGNTSAKGVEIDPVTGRDVELLWVKGSGGDLGTLTEPGLAVLRLDRLRALVDV
YPGEGREDEMVAAFDFCLHGRGGAAPSIDTAMHGLVDASHVDHLHPDSGIALATAADGEQLTKDVFGTKVAWVPWRRPGF
QLGLDIAAVRRDNPGAVGCILGGHGITAWGDTSEESERNSTWIIEQARLHLERHGRPRPFGAVADGRRALPAGQRRARAA
VLAPHLRAVASRDHRMVGHFTDSDAVLEFLASEKLFALARLGTSCPDHFLRTKVRPLVLDLPAAASPEECVRRLAELHEA
YRADYRAYYERHATADSPPMRGADPAIILVPGVGMFSYGRDKQTARVAGEFYVNAINVMRGAEAVSSYAPIPEREKFRIE
YWALEEAKLRRLPPPKRHAGRVALVTGAASGIGRATASRLAADGACVVVADLDATSAVSAAGELGGADVAVGVGADVTKE
AEVAAAVAAALLAFGGIDLVVNNAGLSISKPLLETTERDWDLQHDVMAKGSFLVARAAARAMIDQRLGGDIVYIVSKNAL
FAGPNNVAYGAAKADQAHQVRLLAAELGEHGIRVNGVNPDGVVRGSGIFAGGWGAQRAAVYGIPEEELGAFYARRTLLGR
EVLPEHVANAVAAVCSTELSHTTGLLVPVDAGVAAAFLR

Sequences:

>Translated_679_residues
MSGNQTVAELLARSNRLGADPRNTNYAGGNTSAKGVEIDPVTGRDVELLWVKGSGGDLGTLTEPGLAVLRLDRLRALVDV
YPGEGREDEMVAAFDFCLHGRGGAAPSIDTAMHGLVDASHVDHLHPDSGIALATAADGEQLTKDVFGTKVAWVPWRRPGF
QLGLDIAAVRRDNPGAVGCILGGHGITAWGDTSEESERNSTWIIEQARLHLERHGRPRPFGAVADGRRALPAGQRRARAA
VLAPHLRAVASRDHRMVGHFTDSDAVLEFLASEKLFALARLGTSCPDHFLRTKVRPLVLDLPAAASPEECVRRLAELHEA
YRADYRAYYERHATADSPPMRGADPAIILVPGVGMFSYGRDKQTARVAGEFYVNAINVMRGAEAVSSYAPIPEREKFRIE
YWALEEAKLRRLPPPKRHAGRVALVTGAASGIGRATASRLAADGACVVVADLDATSAVSAAGELGGADVAVGVGADVTKE
AEVAAAVAAALLAFGGIDLVVNNAGLSISKPLLETTERDWDLQHDVMAKGSFLVARAAARAMIDQRLGGDIVYIVSKNAL
FAGPNNVAYGAAKADQAHQVRLLAAELGEHGIRVNGVNPDGVVRGSGIFAGGWGAQRAAVYGIPEEELGAFYARRTLLGR
EVLPEHVANAVAAVCSTELSHTTGLLVPVDAGVAAAFLR
>Mature_678_residues
SGNQTVAELLARSNRLGADPRNTNYAGGNTSAKGVEIDPVTGRDVELLWVKGSGGDLGTLTEPGLAVLRLDRLRALVDVY
PGEGREDEMVAAFDFCLHGRGGAAPSIDTAMHGLVDASHVDHLHPDSGIALATAADGEQLTKDVFGTKVAWVPWRRPGFQ
LGLDIAAVRRDNPGAVGCILGGHGITAWGDTSEESERNSTWIIEQARLHLERHGRPRPFGAVADGRRALPAGQRRARAAV
LAPHLRAVASRDHRMVGHFTDSDAVLEFLASEKLFALARLGTSCPDHFLRTKVRPLVLDLPAAASPEECVRRLAELHEAY
RADYRAYYERHATADSPPMRGADPAIILVPGVGMFSYGRDKQTARVAGEFYVNAINVMRGAEAVSSYAPIPEREKFRIEY
WALEEAKLRRLPPPKRHAGRVALVTGAASGIGRATASRLAADGACVVVADLDATSAVSAAGELGGADVAVGVGADVTKEA
EVAAAVAAALLAFGGIDLVVNNAGLSISKPLLETTERDWDLQHDVMAKGSFLVARAAARAMIDQRLGGDIVYIVSKNALF
AGPNNVAYGAAKADQAHQVRLLAAELGEHGIRVNGVNPDGVVRGSGIFAGGWGAQRAAVYGIPEEELGAFYARRTLLGRE
VLPEHVANAVAAVCSTELSHTTGLLVPVDAGVAAAFLR

Specific function: Catalyzes A Reversible Reduction Of 5-Ketoglutanate To Form D-Gluconate. Dependent On Nadp, Almost Inactive With NAD. [C]

COG id: COG3347

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI7705925, Length=264, Percent_Identity=33.7121212121212, Blast_Score=98, Evalue=3e-20,
Organism=Homo sapiens, GI4504505, Length=264, Percent_Identity=32.1969696969697, Blast_Score=92, Evalue=2e-18,
Organism=Homo sapiens, GI15277342, Length=261, Percent_Identity=34.0996168582375, Blast_Score=92, Evalue=2e-18,
Organism=Homo sapiens, GI32483357, Length=256, Percent_Identity=32.8125, Blast_Score=90, Evalue=5e-18,
Organism=Homo sapiens, GI19923817, Length=276, Percent_Identity=29.3478260869565, Blast_Score=89, Evalue=2e-17,
Organism=Homo sapiens, GI126723191, Length=200, Percent_Identity=33, Blast_Score=76, Evalue=9e-14,
Organism=Homo sapiens, GI5031737, Length=254, Percent_Identity=31.8897637795276, Blast_Score=74, Evalue=7e-13,
Organism=Homo sapiens, GI40254992, Length=179, Percent_Identity=34.6368715083799, Blast_Score=73, Evalue=1e-12,
Organism=Homo sapiens, GI40254986, Length=255, Percent_Identity=30.5882352941176, Blast_Score=73, Evalue=1e-12,
Organism=Homo sapiens, GI126723750, Length=262, Percent_Identity=30.5343511450382, Blast_Score=72, Evalue=2e-12,
Organism=Homo sapiens, GI33667109, Length=192, Percent_Identity=34.8958333333333, Blast_Score=69, Evalue=1e-11,
Organism=Homo sapiens, GI4758504, Length=193, Percent_Identity=34.1968911917098, Blast_Score=69, Evalue=2e-11,
Organism=Escherichia coli, GI1790717, Length=259, Percent_Identity=29.3436293436293, Blast_Score=92, Evalue=9e-20,
Organism=Escherichia coli, GI1789208, Length=254, Percent_Identity=29.9212598425197, Blast_Score=92, Evalue=1e-19,
Organism=Escherichia coli, GI1787905, Length=259, Percent_Identity=30.8880308880309, Blast_Score=89, Evalue=9e-19,
Organism=Escherichia coli, GI1789057, Length=255, Percent_Identity=30.1960784313725, Blast_Score=86, Evalue=6e-18,
Organism=Escherichia coli, GI87082100, Length=258, Percent_Identity=31.0077519379845, Blast_Score=84, Evalue=3e-17,
Organism=Escherichia coli, GI87082160, Length=185, Percent_Identity=34.0540540540541, Blast_Score=84, Evalue=3e-17,
Organism=Escherichia coli, GI1787335, Length=255, Percent_Identity=30.5882352941176, Blast_Score=81, Evalue=3e-16,
Organism=Escherichia coli, GI1788459, Length=258, Percent_Identity=30.2325581395349, Blast_Score=78, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI115534694, Length=264, Percent_Identity=29.5454545454545, Blast_Score=91, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17561402, Length=266, Percent_Identity=30.4511278195489, Blast_Score=88, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI71982365, Length=196, Percent_Identity=35.7142857142857, Blast_Score=83, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17559104, Length=237, Percent_Identity=31.2236286919831, Blast_Score=82, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI193204405, Length=202, Percent_Identity=30.1980198019802, Blast_Score=79, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17568967, Length=191, Percent_Identity=35.6020942408377, Blast_Score=78, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17538480, Length=255, Percent_Identity=31.3725490196078, Blast_Score=76, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI71994604, Length=262, Percent_Identity=30.1526717557252, Blast_Score=76, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI17544670, Length=211, Percent_Identity=32.2274881516588, Blast_Score=75, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI25147288, Length=259, Percent_Identity=30.5019305019305, Blast_Score=75, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17560332, Length=276, Percent_Identity=31.8840579710145, Blast_Score=74, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17563726, Length=249, Percent_Identity=29.718875502008, Blast_Score=72, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI17536025, Length=262, Percent_Identity=27.8625954198473, Blast_Score=72, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI17562904, Length=275, Percent_Identity=27.6363636363636, Blast_Score=72, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI17562906, Length=272, Percent_Identity=27.2058823529412, Blast_Score=71, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17531453, Length=271, Percent_Identity=28.7822878228782, Blast_Score=70, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI71994600, Length=263, Percent_Identity=29.277566539924, Blast_Score=70, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17536651, Length=258, Percent_Identity=26.3565891472868, Blast_Score=70, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17562908, Length=268, Percent_Identity=26.865671641791, Blast_Score=69, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI17555706, Length=256, Percent_Identity=28.515625, Blast_Score=69, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI72000259, Length=250, Percent_Identity=30.4, Blast_Score=69, Evalue=9e-12,
Organism=Caenorhabditis elegans, GI17560150, Length=275, Percent_Identity=26.9090909090909, Blast_Score=68, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17551412, Length=258, Percent_Identity=31.0077519379845, Blast_Score=68, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17562990, Length=280, Percent_Identity=26.7857142857143, Blast_Score=67, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17560676, Length=268, Percent_Identity=26.865671641791, Blast_Score=67, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6322861, Length=191, Percent_Identity=30.8900523560209, Blast_Score=67, Evalue=7e-12,
Organism=Drosophila melanogaster, GI24639444, Length=259, Percent_Identity=35.1351351351351, Blast_Score=114, Evalue=2e-25,
Organism=Drosophila melanogaster, GI24644339, Length=257, Percent_Identity=31.9066147859922, Blast_Score=94, Evalue=5e-19,
Organism=Drosophila melanogaster, GI28571526, Length=257, Percent_Identity=31.9066147859922, Blast_Score=92, Evalue=1e-18,
Organism=Drosophila melanogaster, GI23397609, Length=264, Percent_Identity=33.7121212121212, Blast_Score=92, Evalue=1e-18,
Organism=Drosophila melanogaster, GI18859837, Length=196, Percent_Identity=34.6938775510204, Blast_Score=92, Evalue=2e-18,
Organism=Drosophila melanogaster, GI21357041, Length=257, Percent_Identity=31.1284046692607, Blast_Score=92, Evalue=2e-18,
Organism=Drosophila melanogaster, GI21357673, Length=203, Percent_Identity=33.9901477832512, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI21355319, Length=267, Percent_Identity=30.3370786516854, Blast_Score=82, Evalue=1e-15,
Organism=Drosophila melanogaster, GI17737361, Length=189, Percent_Identity=37.037037037037, Blast_Score=82, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24640492, Length=217, Percent_Identity=30.4147465437788, Blast_Score=74, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24644337, Length=256, Percent_Identity=30.859375, Blast_Score=72, Evalue=1e-12,
Organism=Drosophila melanogaster, GI161076933, Length=221, Percent_Identity=30.316742081448, Blast_Score=68, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24584748, Length=221, Percent_Identity=30.316742081448, Blast_Score=67, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001303
- InterPro:   IPR013454
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040 [H]

Pfam domain/function: PF00106 adh_short; PF00596 Aldolase_II [H]

EC number: 1.1.1.69 [C]

Molecular weight: Translated: 71738; Mature: 71607

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGNQTVAELLARSNRLGADPRNTNYAGGNTSAKGVEIDPVTGRDVELLWVKGSGGDLGT
CCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCEEEEEEECCCCCCCC
LTEPGLAVLRLDRLRALVDVYPGEGREDEMVAAFDFCLHGRGGAAPSIDTAMHGLVDASH
CCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCEEEHHHHCCCCCCCCCHHHHHHHHHCHHH
VDHLHPDSGIALATAADGEQLTKDVFGTKVAWVPWRRPGFQLGLDIAAVRRDNPGAVGCI
CCCCCCCCCEEEEEECCHHHHHHHHHCCEEEEECCCCCCCEECCEEEEEECCCCCEEEEE
LGGHGITAWGDTSEESERNSTWIIEQARLHLERHGRPRPFGAVADGRRALPAGQRRARAA
EECCEEEECCCCCCCCCCCCEEEEHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHH
VLAPHLRAVASRDHRMVGHFTDSDAVLEFLASEKLFALARLGTSCPDHFLRTKVRPLVLD
HHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCEEEE
LPAAASPEECVRRLAELHEAYRADYRAYYERHATADSPPMRGADPAIILVPGVGMFSYGR
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCCCCCCC
DKQTARVAGEFYVNAINVMRGAEAVSSYAPIPEREKFRIEYWALEEAKLRRLPPPKRHAG
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEECHHHHHCCCCCCHHCC
RVALVTGAASGIGRATASRLAADGACVVVADLDATSAVSAAGELGGADVAVGVGADVTKE
CEEEEECCCCCCHHHHHHHHCCCCCEEEEEECCCHHHHHHHHCCCCCCEEEECCCCCCHH
AEVAAAVAAALLAFGGIDLVVNNAGLSISKPLLETTERDWDLQHDVMAKGSFLVARAAAR
HHHHHHHHHHHHHHCCEEEEEECCCCCCCCHHHHHCCCCCCCCHHHHHCCCHHHHHHHHH
AMIDQRLGGDIVYIVSKNALFAGPNNVAYGAAKADQAHQVRLLAAELGEHGIRVNGVNPD
HHHHHHCCCCEEEEEECCEEEECCCCCEECCCCCCCHHHHHHHHHHHCCCCEEEECCCCC
GVVRGSGIFAGGWGAQRAAVYGIPEEELGAFYARRTLLGREVLPEHVANAVAAVCSTELS
CEEECCCEEECCCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HTTGLLVPVDAGVAAAFLR
HCCCEEEEECCCHHHHHCC
>Mature Secondary Structure 
SGNQTVAELLARSNRLGADPRNTNYAGGNTSAKGVEIDPVTGRDVELLWVKGSGGDLGT
CCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCEEEEEEECCCCCCCC
LTEPGLAVLRLDRLRALVDVYPGEGREDEMVAAFDFCLHGRGGAAPSIDTAMHGLVDASH
CCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCEEEHHHHCCCCCCCCCHHHHHHHHHCHHH
VDHLHPDSGIALATAADGEQLTKDVFGTKVAWVPWRRPGFQLGLDIAAVRRDNPGAVGCI
CCCCCCCCCEEEEEECCHHHHHHHHHCCEEEEECCCCCCCEECCEEEEEECCCCCEEEEE
LGGHGITAWGDTSEESERNSTWIIEQARLHLERHGRPRPFGAVADGRRALPAGQRRARAA
EECCEEEECCCCCCCCCCCCEEEEHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHH
VLAPHLRAVASRDHRMVGHFTDSDAVLEFLASEKLFALARLGTSCPDHFLRTKVRPLVLD
HHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCEEEE
LPAAASPEECVRRLAELHEAYRADYRAYYERHATADSPPMRGADPAIILVPGVGMFSYGR
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCCCCCCC
DKQTARVAGEFYVNAINVMRGAEAVSSYAPIPEREKFRIEYWALEEAKLRRLPPPKRHAG
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEECHHHHHCCCCCCHHCC
RVALVTGAASGIGRATASRLAADGACVVVADLDATSAVSAAGELGGADVAVGVGADVTKE
CEEEEECCCCCCHHHHHHHHCCCCCEEEEEECCCHHHHHHHHCCCCCCEEEECCCCCCHH
AEVAAAVAAALLAFGGIDLVVNNAGLSISKPLLETTERDWDLQHDVMAKGSFLVARAAAR
HHHHHHHHHHHHHHCCEEEEEECCCCCCCCHHHHHCCCCCCCCHHHHHCCCHHHHHHHHH
AMIDQRLGGDIVYIVSKNALFAGPNNVAYGAAKADQAHQVRLLAAELGEHGIRVNGVNPD
HHHHHHCCCCEEEEEECCEEEECCCCCEECCCCCCCHHHHHHHHHHHCCCCEEEECCCCC
GVVRGSGIFAGGWGAQRAAVYGIPEEELGAFYARRTLLGREVLPEHVANAVAAVCSTELS
CEEECCCEEECCCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HTTGLLVPVDAGVAAAFLR
HCCCEEEEECCCHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NAD+; NADH; NADP+; NADPH [C]

Metal ions: Mn2+ [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): 0.006 {NADPH}} 0.9 {5-keto-D-gluconate}} 0.02 {NADP+}} 20 {D-gluconate}} [C]

Substrates: 5-Dehydro-D-gluconate; H+; Nicotinamide adenine dinucleotide phosphate - reduced [C]

Specific reaction: 5-Dehydro-D-gluconate + H+ + Nicotinamide adenine dinucleotide phosphate - reduced <==> D-Gluconate + Nicotinamide adenine dinucleotide phosphate [C]

General reaction: Redox reaction [C]

Inhibitor: Cd2+; Cs2+; Cu2+; Divalent metal ions; Hg2+; Ni2+; p-Chloromercuribenzoate; Sn2+; Sulfhydryl reagents [C]

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9274030; 9384377; 8188684 [H]