Click here to switch to the map view.

The map label for this gene is uidA [H]

Identifier: 158315059

GI number: 158315059

Start: 3851938

End: 3853734

Strand: Direct

Name: uidA [H]

Synonym: Franean1_3255

Alternate gene names: 158315059

Gene position: 3851938-3853734 (Clockwise)

Preceding gene: 158315058

Following gene: 158315063

Centisome position: 42.88

GC content: 68.61

Gene sequence:

>1797_bases
ATGTTGCGTCCCCGGGACACTGCCACGCGTGAGCGCAGGAACCTGAGCGGGTTGTGGGCGTTCCGCCTCGACCCGGCCGG
GGTCGGGCGCGAGGCGGGCTGGTGGCAGGGCCGCCTGCCCGAGGCACGCGAGATGCCCGTGCCGGCCAGCTACAACGACG
TCCTCGTCGACGCGGGGGTACGGGACCACATCGGTGACGCCTGGTATCAGACGACGGTGCGTGTCCCGCGGGGCTGGGCG
GGACAGCGGGTCGTGCTGCGTTTCGACTCGGCGACCCACCGCGCGGTGGTCTGGGTGGACGACGTGGAGGTCGCCAGCCA
CGAGGGTGGCTACACCCCGTTCGAGGCGGACATCACCGCGTACGCGCGGCCGGGCCGGGAGATCCGGGTGACAGCGGTGG
TGAACAACGAGCTGACCTGGCAGTCGGTACCGCCGGGAGTGGTCGAGGACACCCCCTCCGGCCGCCGGCAGAACTACTTC
CACGACTTCTTCAACTACGCAGGCCTGCACCGGCCGGTCTGGCTCTACTGCACCTCGCCGGACCACATTGACGACATCAC
CGTCGTGACCGGACTCGACGGAGCCGTCGGCACTGTCGACTACCGCGTCGAGGTGGCTGGTGCCGGCGAGGCCGCCGGCG
ACGCGGTCCGGCAGATTCGCGCGGTGCTCGAGGACGCGGAGGGAGCCGAGGTGGCGCGGTCCACCGGCGCCTCGGGTGTC
CTGACGGTCGAGGGCGTGCGGCCGTGGCAGCCGGGTGCGGGATACCTCTACACCCTGCGGGTGGAACTAGCCGACGGCGG
CGAGCTGGTCGACGACTACACCCTGGCGGTCGGCATCCGCACGGTGGAGATCGACGGCACGAATTTCCTGATCAACGGCG
AGCCGTTCTATTTCACCGGGTTCGGCAAGCACGAGGATCTGCCGATCCGGGGCAAGGGCCATGACGACGTTTTCCTGGTC
CACGACTTCGCCCTGATGGAGTGGATCGGCGCGAACTCGTTCCGGACGTCGCACTATCCGTACGCCGAGGAGGTGCTCGA
CCACGCCGATCGCCACGGGATCGTCGTGATCGACGAGACGGCGGCCGTCGGCCAGAACACCGGGGTCGGCGGCGGCATCG
TCGGGTCGCGCCCGTATCCGACCTTCTCGCCGGAGACGATCAACGATGCCAGCCGCGACGTCCATGCCCAGGCCATCCGG
GAACTCGTCGCCCGGGACAAGAACCATCCGTGCGTCGTGCTCTGGAGCGTCGCCAACGAGCCGGAGTCGACCACCGAGGC
GTCCCGGGACTACTTCGAGCCGTTGTTCGCGCTCACCCGCGAACTCGACCCGACCCGGCCGGTGGGCTTCGTGAACATGT
TGCTGGCGCGGCCCGGGATGGACCTGGTCATGCAGTTCTCCGATGTGATCATGCTCAACCGGTACTACGGCTGGTACCTG
AACACCGGTGACCTGGCAGGTGCGGAGACGGCCTGGCAGGCCGAACTCGAGGGCTGGGCGGCCGAGGGCAAGCCGATCAT
CATCACCGAGTACGGGGCCGACACCATCACCGGCCTCCACCAGGTCACGCCGCAGCCGTGGAGCGAGGAGTACCAGGCCG
AGTACCTGGAGATGAACCACCGCGTCTTCGACCGGATCGACGCCGTGATCGGCGAGCATGTGTGGAACTTCGCCGACTTC
GCCACGAAGTCGGCGATCTTCCGGGTGGACGGGAACAAGAAGGGAGTCTTCACCCGGGACCGCCACCCGAAGTCCGCCGC
CCACACACTGCGCCGCCGCTGGCGCGGCAAGAACTGA

Upstream 100 bases:

>100_bases
CTTCGCGCGGGCGGTGAAGCCGTCGGCGCGCTGGCTCGGCGCGGTCGCGCGCGCCAACGGACTCGTCTGACGGCCCAGGA
AAAAAGAAGGAAGGAAGTTC

Downstream 100 bases:

>100_bases
GGCCGGCGCGGGCCGGGCCACCGGGGCGGTGGCCGGTCCGTGTGCGCCGGCCGGTACCGGTCCTCAGGATGCCCCGGCGC
GGGGCGCCACCGCGGCGACC

Product: beta-D-glucuronidase

Products: NA

Alternate protein names: GUS; Beta-D-glucuronoside glucuronosohydrolase [H]

Number of amino acids: Translated: 598; Mature: 598

Protein sequence:

>598_residues
MLRPRDTATRERRNLSGLWAFRLDPAGVGREAGWWQGRLPEAREMPVPASYNDVLVDAGVRDHIGDAWYQTTVRVPRGWA
GQRVVLRFDSATHRAVVWVDDVEVASHEGGYTPFEADITAYARPGREIRVTAVVNNELTWQSVPPGVVEDTPSGRRQNYF
HDFFNYAGLHRPVWLYCTSPDHIDDITVVTGLDGAVGTVDYRVEVAGAGEAAGDAVRQIRAVLEDAEGAEVARSTGASGV
LTVEGVRPWQPGAGYLYTLRVELADGGELVDDYTLAVGIRTVEIDGTNFLINGEPFYFTGFGKHEDLPIRGKGHDDVFLV
HDFALMEWIGANSFRTSHYPYAEEVLDHADRHGIVVIDETAAVGQNTGVGGGIVGSRPYPTFSPETINDASRDVHAQAIR
ELVARDKNHPCVVLWSVANEPESTTEASRDYFEPLFALTRELDPTRPVGFVNMLLARPGMDLVMQFSDVIMLNRYYGWYL
NTGDLAGAETAWQAELEGWAAEGKPIIITEYGADTITGLHQVTPQPWSEEYQAEYLEMNHRVFDRIDAVIGEHVWNFADF
ATKSAIFRVDGNKKGVFTRDRHPKSAAHTLRRRWRGKN

Sequences:

>Translated_598_residues
MLRPRDTATRERRNLSGLWAFRLDPAGVGREAGWWQGRLPEAREMPVPASYNDVLVDAGVRDHIGDAWYQTTVRVPRGWA
GQRVVLRFDSATHRAVVWVDDVEVASHEGGYTPFEADITAYARPGREIRVTAVVNNELTWQSVPPGVVEDTPSGRRQNYF
HDFFNYAGLHRPVWLYCTSPDHIDDITVVTGLDGAVGTVDYRVEVAGAGEAAGDAVRQIRAVLEDAEGAEVARSTGASGV
LTVEGVRPWQPGAGYLYTLRVELADGGELVDDYTLAVGIRTVEIDGTNFLINGEPFYFTGFGKHEDLPIRGKGHDDVFLV
HDFALMEWIGANSFRTSHYPYAEEVLDHADRHGIVVIDETAAVGQNTGVGGGIVGSRPYPTFSPETINDASRDVHAQAIR
ELVARDKNHPCVVLWSVANEPESTTEASRDYFEPLFALTRELDPTRPVGFVNMLLARPGMDLVMQFSDVIMLNRYYGWYL
NTGDLAGAETAWQAELEGWAAEGKPIIITEYGADTITGLHQVTPQPWSEEYQAEYLEMNHRVFDRIDAVIGEHVWNFADF
ATKSAIFRVDGNKKGVFTRDRHPKSAAHTLRRRWRGKN
>Mature_598_residues
MLRPRDTATRERRNLSGLWAFRLDPAGVGREAGWWQGRLPEAREMPVPASYNDVLVDAGVRDHIGDAWYQTTVRVPRGWA
GQRVVLRFDSATHRAVVWVDDVEVASHEGGYTPFEADITAYARPGREIRVTAVVNNELTWQSVPPGVVEDTPSGRRQNYF
HDFFNYAGLHRPVWLYCTSPDHIDDITVVTGLDGAVGTVDYRVEVAGAGEAAGDAVRQIRAVLEDAEGAEVARSTGASGV
LTVEGVRPWQPGAGYLYTLRVELADGGELVDDYTLAVGIRTVEIDGTNFLINGEPFYFTGFGKHEDLPIRGKGHDDVFLV
HDFALMEWIGANSFRTSHYPYAEEVLDHADRHGIVVIDETAAVGQNTGVGGGIVGSRPYPTFSPETINDASRDVHAQAIR
ELVARDKNHPCVVLWSVANEPESTTEASRDYFEPLFALTRELDPTRPVGFVNMLLARPGMDLVMQFSDVIMLNRYYGWYL
NTGDLAGAETAWQAELEGWAAEGKPIIITEYGADTITGLHQVTPQPWSEEYQAEYLEMNHRVFDRIDAVIGEHVWNFADF
ATKSAIFRVDGNKKGVFTRDRHPKSAAHTLRRRWRGKN

Specific function: Unknown

COG id: COG3250

COG function: function code G; Beta-galactosidase/beta-glucuronidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 2 family [H]

Homologues:

Organism=Homo sapiens, GI268834192, Length=629, Percent_Identity=44.9920508744038, Blast_Score=477, Evalue=1e-134,
Organism=Escherichia coli, GI1787903, Length=603, Percent_Identity=54.3946932006633, Blast_Score=662, Evalue=0.0,
Organism=Escherichia coli, GI48994920, Length=506, Percent_Identity=24.3083003952569, Blast_Score=115, Evalue=8e-27,
Organism=Escherichia coli, GI1786539, Length=481, Percent_Identity=27.2349272349272, Blast_Score=108, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI17510825, Length=626, Percent_Identity=36.4217252396166, Blast_Score=365, Evalue=1e-101,
Organism=Drosophila melanogaster, GI24655438, Length=620, Percent_Identity=43.3870967741936, Blast_Score=467, Evalue=1e-131,
Organism=Drosophila melanogaster, GI62471735, Length=620, Percent_Identity=43.3870967741936, Blast_Score=466, Evalue=1e-131,
Organism=Drosophila melanogaster, GI19922582, Length=620, Percent_Identity=43.3870967741936, Blast_Score=466, Evalue=1e-131,
Organism=Drosophila melanogaster, GI24651745, Length=625, Percent_Identity=40.96, Blast_Score=436, Evalue=1e-122,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008979
- InterPro:   IPR006101
- InterPro:   IPR013812
- InterPro:   IPR006104
- InterPro:   IPR006102
- InterPro:   IPR006103
- InterPro:   IPR017853
- InterPro:   IPR013781 [H]

Pfam domain/function: PF00703 Glyco_hydro_2; PF02836 Glyco_hydro_2_C; PF02837 Glyco_hydro_2_N [H]

EC number: =3.2.1.31 [H]

Molecular weight: Translated: 66582; Mature: 66582

Theoretical pI: Translated: 4.92; Mature: 4.92

Prosite motif: PS00719 GLYCOSYL_HYDROL_F2_1 ; PS00608 GLYCOSYL_HYDROL_F2_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLRPRDTATRERRNLSGLWAFRLDPAGVGREAGWWQGRLPEAREMPVPASYNDVLVDAGV
CCCCCCCHHHHHCCCCEEEEEEECCCCCCCCCCCCCCCCCCHHCCCCCCCCCCEEEECCC
RDHIGDAWYQTTVRVPRGWAGQRVVLRFDSATHRAVVWVDDVEVASHEGGYTPFEADITA
HHHCCCHHEEEEEECCCCCCCCEEEEEECCCCCEEEEEEECEEEECCCCCCCCCCCCEEE
YARPGREIRVTAVVNNELTWQSVPPGVVEDTPSGRRQNYFHDFFNYAGLHRPVWLYCTSP
EECCCCEEEEEEEECCCEEECCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCEEEEECCC
DHIDDITVVTGLDGAVGTVDYRVEVAGAGEAAGDAVRQIRAVLEDAEGAEVARSTGASGV
CCCCCEEEEECCCCCEEEEEEEEEEECCCCHHHHHHHHHHHHHHCCCCHHHHHHCCCCCE
LTVEGVRPWQPGAGYLYTLRVELADGGELVDDYTLAVGIRTVEIDGTNFLINGEPFYFTG
EEECCCCCCCCCCCEEEEEEEEECCCCCCCCCEEEEEEEEEEEECCCEEEECCCCEEEEC
FGKHEDLPIRGKGHDDVFLVHDFALMEWIGANSFRTSHYPYAEEVLDHADRHGIVVIDET
CCCCCCCCCCCCCCCCEEEEEHHHHHHHHCCCCCCCCCCCHHHHHHHHCCCCCEEEEECC
AAVGQNTGVGGGIVGSRPYPTFSPETINDASRDVHAQAIRELVARDKNHPCVVLWSVANE
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEECCCC
PESTTEASRDYFEPLFALTRELDPTRPVGFVNMLLARPGMDLVMQFSDVIMLNRYYGWYL
CCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCHHHHHHHHHEEEEECEEEEEE
NTGDLAGAETAWQAELEGWAAEGKPIIITEYGADTITGLHQVTPQPWSEEYQAEYLEMNH
ECCCCCCCCCHHHHHHCCCCCCCCEEEEEECCCHHHHHHHHCCCCCCCHHHHHHHHHHHH
RVFDRIDAVIGEHVWNFADFATKSAIFRVDGNKKGVFTRDRHPKSAAHTLRRRWRGKN
HHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCEECCCCCHHHHHHHHHHHCCCC
>Mature Secondary Structure
MLRPRDTATRERRNLSGLWAFRLDPAGVGREAGWWQGRLPEAREMPVPASYNDVLVDAGV
CCCCCCCHHHHHCCCCEEEEEEECCCCCCCCCCCCCCCCCCHHCCCCCCCCCCEEEECCC
RDHIGDAWYQTTVRVPRGWAGQRVVLRFDSATHRAVVWVDDVEVASHEGGYTPFEADITA
HHHCCCHHEEEEEECCCCCCCCEEEEEECCCCCEEEEEEECEEEECCCCCCCCCCCCEEE
YARPGREIRVTAVVNNELTWQSVPPGVVEDTPSGRRQNYFHDFFNYAGLHRPVWLYCTSP
EECCCCEEEEEEEECCCEEECCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCEEEEECCC
DHIDDITVVTGLDGAVGTVDYRVEVAGAGEAAGDAVRQIRAVLEDAEGAEVARSTGASGV
CCCCCEEEEECCCCCEEEEEEEEEEECCCCHHHHHHHHHHHHHHCCCCHHHHHHCCCCCE
LTVEGVRPWQPGAGYLYTLRVELADGGELVDDYTLAVGIRTVEIDGTNFLINGEPFYFTG
EEECCCCCCCCCCCEEEEEEEEECCCCCCCCCEEEEEEEEEEEECCCEEEECCCCEEEEC
FGKHEDLPIRGKGHDDVFLVHDFALMEWIGANSFRTSHYPYAEEVLDHADRHGIVVIDET
CCCCCCCCCCCCCCCCEEEEEHHHHHHHHCCCCCCCCCCCHHHHHHHHCCCCCEEEEECC
AAVGQNTGVGGGIVGSRPYPTFSPETINDASRDVHAQAIRELVARDKNHPCVVLWSVANE
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEECCCC
PESTTEASRDYFEPLFALTRELDPTRPVGFVNMLLARPGMDLVMQFSDVIMLNRYYGWYL
CCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCHHHHHHHHHEEEEECEEEEEE
NTGDLAGAETAWQAELEGWAAEGKPIIITEYGADTITGLHQVTPQPWSEEYQAEYLEMNH
ECCCCCCCCCHHHHHHCCCCCCCCEEEEEECCCHHHHHHHHCCCCCCCHHHHHHHHHHHH
RVFDRIDAVIGEHVWNFADFATKSAIFRVDGNKKGVFTRDRHPKSAAHTLRRRWRGKN
HHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCEECCCCCHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3534890; 8125312; 2103475; 9097039; 9278503 [H]