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The map label for this gene is mlhB [H]

Identifier: 158315033

GI number: 158315033

Start: 3814656

End: 3815651

Strand: Direct

Name: mlhB [H]

Synonym: Franean1_3228

Alternate gene names: 158315033

Gene position: 3814656-3815651 (Clockwise)

Preceding gene: 158315032

Following gene: 158315034

Centisome position: 42.47

GC content: 70.28

Gene sequence:

>996_bases
ATGAGCGCTGATATCGCGCAACCGGCGATGCGTGTGCCGGAAAGAGAGATCCCGGTGCCCCCGACGGTGAGTCCCGAGGG
CCAGGCGATGCTGGCACTGGGCATGGTAGGGCCGGAGCCGGAGTGGAACGGCGTCGAGCTCGACGCGGCCGGGTGGAAGA
AGCTGATCGCCGAGCGCGAGGCAGCTGTGATCGCCATGACCGGGGTGGGCGGTGCGTACGTCGGAGCCGAGGTCGAGGAG
GAGGACCTGGGTGGCTTCGTGGTCTTCAAGATTCGTCCGGACGGGGTGGCGGTGGACGATCGCCGGGTCTACCTCGACTT
CCACGGCGGCGGCTTCATTCAGGACGGCGGCCAGATCGCCTGCTCCCGTGCGGTCGACGAGGCCCGGCGCCTCGGGGCCG
CTGTCTGGTCGGTCGACTACCGGATGCCGCCCGACCACCCGTTCCCGGCCGGAGTCGACGACGGCGTAGCGGCCTACCGG
CGACTGCTCGAGGTGCGGCGGCCGGAGGAGATCGTCATCGGCGGTTCGTCGGCCGGCGGGAACCTGGCGGCGGCGACGAT
CCTCAAGGCCCGCGACGGGGGCCTGCCGCTGCCGGCGGCGGCGGTACTGAACACCCCCTGCACCGACCTGACGGAAAGCA
GCGACAGCTGGTGGACGAACGAGGGCGTCGACACCGTGCTGCGCGGCGGCTTCAAGCCCGCCTTCGAGCTCTGGGCGGGT
GGCCACGACCTGAGGAATCCCTATATCTCGGTGGTGTACGCCGACCTCACCAAGGGATTCCCACCGACCATTCTCACCAC
CGGTACCCGCGACAGGCTGCTGTCCGACACGGTGCGTTTCCACCGGGCCCTGCTCCGGGCCGGCATGCAGGCCGAACTGC
ACGTCTGGGAAGCCATGGGGCACGCCGGATTCCTTGGGACGTCGCCGGAGGACGCCGAGCGTGCCGCTGAGATCCGCCGG
TTCTGCGCCGCTCACTGGGCGGCTGACGCGGCCTGA

Upstream 100 bases:

>100_bases
CGGCGAGACCTCCGGGCCGGTGTGCGGGTGGCGGAGCGAGTGGCCGACACGCAGTGACAAGAGGCGTGAGGAACGAACCG
AAGAACAAGGAGAGCAGACG

Downstream 100 bases:

>100_bases
TCGGGACCGCGTTTCATGACAATCCCGCGAGCATGCAAAGGAGAAGCTATGAGTTACCGAGTCGAGAAGAACGTCATGGT
TCCGATGCGGGACGACGTGA

Product: alpha/beta hydrolase domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 331; Mature: 330

Protein sequence:

>331_residues
MSADIAQPAMRVPEREIPVPPTVSPEGQAMLALGMVGPEPEWNGVELDAAGWKKLIAEREAAVIAMTGVGGAYVGAEVEE
EDLGGFVVFKIRPDGVAVDDRRVYLDFHGGGFIQDGGQIACSRAVDEARRLGAAVWSVDYRMPPDHPFPAGVDDGVAAYR
RLLEVRRPEEIVIGGSSAGGNLAAATILKARDGGLPLPAAAVLNTPCTDLTESSDSWWTNEGVDTVLRGGFKPAFELWAG
GHDLRNPYISVVYADLTKGFPPTILTTGTRDRLLSDTVRFHRALLRAGMQAELHVWEAMGHAGFLGTSPEDAERAAEIRR
FCAAHWAADAA

Sequences:

>Translated_331_residues
MSADIAQPAMRVPEREIPVPPTVSPEGQAMLALGMVGPEPEWNGVELDAAGWKKLIAEREAAVIAMTGVGGAYVGAEVEE
EDLGGFVVFKIRPDGVAVDDRRVYLDFHGGGFIQDGGQIACSRAVDEARRLGAAVWSVDYRMPPDHPFPAGVDDGVAAYR
RLLEVRRPEEIVIGGSSAGGNLAAATILKARDGGLPLPAAAVLNTPCTDLTESSDSWWTNEGVDTVLRGGFKPAFELWAG
GHDLRNPYISVVYADLTKGFPPTILTTGTRDRLLSDTVRFHRALLRAGMQAELHVWEAMGHAGFLGTSPEDAERAAEIRR
FCAAHWAADAA
>Mature_330_residues
SADIAQPAMRVPEREIPVPPTVSPEGQAMLALGMVGPEPEWNGVELDAAGWKKLIAEREAAVIAMTGVGGAYVGAEVEEE
DLGGFVVFKIRPDGVAVDDRRVYLDFHGGGFIQDGGQIACSRAVDEARRLGAAVWSVDYRMPPDHPFPAGVDDGVAAYRR
LLEVRRPEEIVIGGSSAGGNLAAATILKARDGGLPLPAAAVLNTPCTDLTESSDSWWTNEGVDTVLRGGFKPAFELWAGG
HDLRNPYISVVYADLTKGFPPTILTTGTRDRLLSDTVRFHRALLRAGMQAELHVWEAMGHAGFLGTSPEDAERAAEIRRF
CAAHWAADAA

Specific function: Lactone hydrolase that is required for the degradation of monocyclic monoterpenes such as menthol and carvone. Catalyzes the ring opening of lactones formed during degradation of monocyclic monoterpenes. Can hydrolyze epsilon-caprolactone, the lactone der

COG id: COG0657

COG function: function code I; Esterase/lipase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'GDXG' lipolytic enzyme family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013094 [H]

Pfam domain/function: PF07859 Abhydrolase_3 [H]

EC number: =3.1.1.83 [H]

Molecular weight: Translated: 35394; Mature: 35263

Theoretical pI: Translated: 4.63; Mature: 4.63

Prosite motif: PS00226 IF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSADIAQPAMRVPEREIPVPPTVSPEGQAMLALGMVGPEPEWNGVELDAAGWKKLIAERE
CCCCCCCHHHHCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCEEECHHHHHHHHHHCC
AAVIAMTGVGGAYVGAEVEEEDLGGFVVFKIRPDGVAVDDRRVYLDFHGGGFIQDGGQIA
CEEEEEECCCCEEECCCCCCCCCCCEEEEEECCCCEEECCCEEEEEECCCCEEECCCCCH
CSRAVDEARRLGAAVWSVDYRMPPDHPFPAGVDDGVAAYRRLLEVRRPEEIVIGGSSAGG
HHHHHHHHHHHHHHHEEEECCCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCC
NLAAATILKARDGGLPLPAAAVLNTPCTDLTESSDSWWTNEGVDTVLRGGFKPAFELWAG
CEEEEEEEEECCCCCCCCHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHCCCCHHHHHHCC
GHDLRNPYISVVYADLTKGFPPTILTTGTRDRLLSDTVRFHRALLRAGMQAELHVWEAMG
CCHHCCCEEEEEEEHHHCCCCCCEEECCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHC
HAGFLGTSPEDAERAAEIRRFCAAHWAADAA
CCCCCCCCCHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SADIAQPAMRVPEREIPVPPTVSPEGQAMLALGMVGPEPEWNGVELDAAGWKKLIAERE
CCCCCCHHHHCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCEEECHHHHHHHHHHCC
AAVIAMTGVGGAYVGAEVEEEDLGGFVVFKIRPDGVAVDDRRVYLDFHGGGFIQDGGQIA
CEEEEEECCCCEEECCCCCCCCCCCEEEEEECCCCEEECCCEEEEEECCCCEEECCCCCH
CSRAVDEARRLGAAVWSVDYRMPPDHPFPAGVDDGVAAYRRLLEVRRPEEIVIGGSSAGG
HHHHHHHHHHHHHHHEEEECCCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCC
NLAAATILKARDGGLPLPAAAVLNTPCTDLTESSDSWWTNEGVDTVLRGGFKPAFELWAG
CEEEEEEEEECCCCCCCCHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHCCCCHHHHHHCC
GHDLRNPYISVVYADLTKGFPPTILTTGTRDRLLSDTVRFHRALLRAGMQAELHVWEAMG
CCHHCCCEEEEEEEHHHCCCCCCEEECCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHC
HAGFLGTSPEDAERAAEIRRFCAAHWAADAA
CCCCCCCCCHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA