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The map label for this gene is cocE [H]

Identifier: 158315034

GI number: 158315034

Start: 3815700

End: 3817466

Strand: Direct

Name: cocE [H]

Synonym: Franean1_3229

Alternate gene names: 158315034

Gene position: 3815700-3817466 (Clockwise)

Preceding gene: 158315033

Following gene: 158315046

Centisome position: 42.48

GC content: 68.14

Gene sequence:

>1767_bases
ATGAGTTACCGAGTCGAGAAGAACGTCATGGTTCCGATGCGGGACGACGTGACGTTATGCACGGATCTCTTCCTGCCGGA
AGGCGGGCCCGCGCCGGCGCTCATAATCCGGATGGGCTACAGCAAGGAGATGTTCGAGAAGTTGTCCCTGCCGCTGATCC
CGAACGTCCTCTCGCTGGTCGAGGCCGGCTACGCGATCGTTTACCAGGAGTGCCGCGGCACCTACGGCTCCGGGGGCGTC
TTCCGGCCGCTCGTGGATGACCCGGACGACGGCGTCGACACGCTCGAATGGACGGTGAAACAGCCGTGGTGCGACGGGAA
CGTCGGCAGCTACGGGCTGTCATACCACGGCATGACCCAGTGGGCGACGGCCTCACAGGCCCCCTCCGGGCTGAAGGCGA
TGGCAGTGGCGGCCTCGACGACGGACCTCTTCCGCGCCCCGTGGTACAGCGACGGCGGTGCCGTGTCCTGGCAGATGACT
CTGGGCTGGGTGGCGGCCCAGATCGTCACGCTGGGCCAGTACGCGCTCGAGCGCGGCACAGGTGACCTCGAGCCGCTGGT
CGACGCGGGCGCGATGATGCTCGACCTGGAGCCGCACCTGCGCAAGCTCCCGATCACCGATCAGCCAGCGCTGAACAAGC
ATGCGCCCTGGTGGAAGGAATGGTGGGAGCACCCCACCCGCGACGAGTTCTGGACCGGCCTGGCGACGGCCGAACACACC
CGGGACATGACGACTCCGGCGCTGCACATCGTCGGCTGGTTCGACTTCTTCGCGCCCGAGGCGACGCGTGCCTACACCCG
AATGCGTGCCCAGGCAGCCACGCCACAGGCACGGGAGGGCCAGCGGCTGATCGTAGGCCCCTGGGACCACACCTACCAGG
ATGCCGCCTACCGGTCCCGCGAGTTCGGCCAGCTGGCCGGCGCACCGTACGCCGACATCACCGGCGCGCACCTGCGGTTC
TTCGACCGGCACCTGCGCGGCAACAACAGCGCCGACGTCGGCGCAAGCCCAGTACGGATCTTCGTGATGGGTGTGGACCA
GTGGCGGGATGAGCAGGACTGGCCACTGCCCGACACCACCTACGTCGACTACTACCTGGACGGGCCCGGCCGCGCGAACA
CCGCCGACGGCGACGGCGTGCTCACGACCGAGGCCCCCACCACCGAGGCGGCCGAGTCCTACCGCTTCGACCCGCTCGAT
CCGGTGCCGACGCTGGGCGGCCGGCTCAACCAGATGGGTTTCGGTTTCTCCGCTCTGTACTCGGGGCCGGTCGACCAGCG
CCCAGTCGAAGAGCGCAACGACGTTCTGTGCTTCACCACGCCGGTGCTGGAGGAGCCGGTCGAGGTCACCGGGAACATAT
CGCTGGTGCTGCATGCGTCGAGCTCCGCGCTGGACACCGACTTCACCGGCAAGCTCGTCGACGTCCACCCCGACGGCCGG
GCGCTCTACCTGACCGACGGCATCCTGCGTGCCCGCTACCGCGAGTCGCTGGCCAACCCGAAGCCACTCGTGCCCGGCGA
GGTCTACGAGCTCATCCTCGACCTCGGCCTGACCTCCAACGTCTTCCTGCCTGGCCACCGCATCCGGCTCGAGGTCTCCT
CCAGCAACTTCCCGCGCTACGACCGGAACACAAATACCGGCAACGTGATCTCCTTCGACACGGCCACCCCGGTCGTCGCG
GGAAACCAGATCCTCCACGGCCCGGCGCATCCCAGCCGGCTCGTTCTGCCGATCATCCGGCGCCTGCGGACCGACCGACA
CGGCTGA

Upstream 100 bases:

>100_bases
CGCTGAGATCCGCCGGTTCTGCGCCGCTCACTGGGCGGCTGACGCGGCCTGATCGGGACCGCGTTTCATGACAATCCCGC
GAGCATGCAAAGGAGAAGCT

Downstream 100 bases:

>100_bases
GGAACCTAGCTCCCCGTGCTGTTGGCGCAGAGGCGTTCCCGGGTGACCTGGAACGCCGAGCCGGTCTGGTCGATCTGCAC
GAAGGCGTTGCATTCGAGGA

Product: X-Pro dipeptidyl-peptidase domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 588; Mature: 587

Protein sequence:

>588_residues
MSYRVEKNVMVPMRDDVTLCTDLFLPEGGPAPALIIRMGYSKEMFEKLSLPLIPNVLSLVEAGYAIVYQECRGTYGSGGV
FRPLVDDPDDGVDTLEWTVKQPWCDGNVGSYGLSYHGMTQWATASQAPSGLKAMAVAASTTDLFRAPWYSDGGAVSWQMT
LGWVAAQIVTLGQYALERGTGDLEPLVDAGAMMLDLEPHLRKLPITDQPALNKHAPWWKEWWEHPTRDEFWTGLATAEHT
RDMTTPALHIVGWFDFFAPEATRAYTRMRAQAATPQAREGQRLIVGPWDHTYQDAAYRSREFGQLAGAPYADITGAHLRF
FDRHLRGNNSADVGASPVRIFVMGVDQWRDEQDWPLPDTTYVDYYLDGPGRANTADGDGVLTTEAPTTEAAESYRFDPLD
PVPTLGGRLNQMGFGFSALYSGPVDQRPVEERNDVLCFTTPVLEEPVEVTGNISLVLHASSSALDTDFTGKLVDVHPDGR
ALYLTDGILRARYRESLANPKPLVPGEVYELILDLGLTSNVFLPGHRIRLEVSSSNFPRYDRNTNTGNVISFDTATPVVA
GNQILHGPAHPSRLVLPIIRRLRTDRHG

Sequences:

>Translated_588_residues
MSYRVEKNVMVPMRDDVTLCTDLFLPEGGPAPALIIRMGYSKEMFEKLSLPLIPNVLSLVEAGYAIVYQECRGTYGSGGV
FRPLVDDPDDGVDTLEWTVKQPWCDGNVGSYGLSYHGMTQWATASQAPSGLKAMAVAASTTDLFRAPWYSDGGAVSWQMT
LGWVAAQIVTLGQYALERGTGDLEPLVDAGAMMLDLEPHLRKLPITDQPALNKHAPWWKEWWEHPTRDEFWTGLATAEHT
RDMTTPALHIVGWFDFFAPEATRAYTRMRAQAATPQAREGQRLIVGPWDHTYQDAAYRSREFGQLAGAPYADITGAHLRF
FDRHLRGNNSADVGASPVRIFVMGVDQWRDEQDWPLPDTTYVDYYLDGPGRANTADGDGVLTTEAPTTEAAESYRFDPLD
PVPTLGGRLNQMGFGFSALYSGPVDQRPVEERNDVLCFTTPVLEEPVEVTGNISLVLHASSSALDTDFTGKLVDVHPDGR
ALYLTDGILRARYRESLANPKPLVPGEVYELILDLGLTSNVFLPGHRIRLEVSSSNFPRYDRNTNTGNVISFDTATPVVA
GNQILHGPAHPSRLVLPIIRRLRTDRHG
>Mature_587_residues
SYRVEKNVMVPMRDDVTLCTDLFLPEGGPAPALIIRMGYSKEMFEKLSLPLIPNVLSLVEAGYAIVYQECRGTYGSGGVF
RPLVDDPDDGVDTLEWTVKQPWCDGNVGSYGLSYHGMTQWATASQAPSGLKAMAVAASTTDLFRAPWYSDGGAVSWQMTL
GWVAAQIVTLGQYALERGTGDLEPLVDAGAMMLDLEPHLRKLPITDQPALNKHAPWWKEWWEHPTRDEFWTGLATAEHTR
DMTTPALHIVGWFDFFAPEATRAYTRMRAQAATPQAREGQRLIVGPWDHTYQDAAYRSREFGQLAGAPYADITGAHLRFF
DRHLRGNNSADVGASPVRIFVMGVDQWRDEQDWPLPDTTYVDYYLDGPGRANTADGDGVLTTEAPTTEAAESYRFDPLDP
VPTLGGRLNQMGFGFSALYSGPVDQRPVEERNDVLCFTTPVLEEPVEVTGNISLVLHASSSALDTDFTGKLVDVHPDGRA
LYLTDGILRARYRESLANPKPLVPGEVYELILDLGLTSNVFLPGHRIRLEVSSSNFPRYDRNTNTGNVISFDTATPVVAG
NQILHGPAHPSRLVLPIIRRLRTDRHG

Specific function: Hydrolyzes cocaine to benzoate and ecgonine methyl ester, endowing the bacteria with the ability to utilize cocaine as a sole source of carbon and energy for growth, as this bacterium lives in the rhizosphere of coca plants [H]

COG id: COG2936

COG function: function code R; Predicted acyl esterases

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the alpha/beta hydrolase family. Carboxylesterase subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005674
- InterPro:   IPR008979
- InterPro:   IPR013736
- InterPro:   IPR000383 [H]

Pfam domain/function: PF02129 Peptidase_S15; PF08530 PepX_C [H]

EC number: NA

Molecular weight: Translated: 65080; Mature: 64949

Theoretical pI: Translated: 4.83; Mature: 4.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSYRVEKNVMVPMRDDVTLCTDLFLPEGGPAPALIIRMGYSKEMFEKLSLPLIPNVLSLV
CCEEECCCEEEECCCCCEEHHHEECCCCCCCCEEEEEECCCHHHHHHCCCCHHHHHHHHH
EAGYAIVYQECRGTYGSGGVFRPLVDDPDDGVDTLEWTVKQPWCDGNVGSYGLSYHGMTQ
HCCHHEEEHHHCCCCCCCCEECCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCEECCCHH
WATASQAPSGLKAMAVAASTTDLFRAPWYSDGGAVSWQMTLGWVAAQIVTLGQYALERGT
HCCCCCCCCCCEEEEEEECCHHHHCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHCCC
GDLEPLVDAGAMMLDLEPHLRKLPITDQPALNKHAPWWKEWWEHPTRDEFWTGLATAEHT
CCCCHHHHCCEEEEECCHHHHCCCCCCCCCCCCCCCHHHHHHCCCCCHHHHHCCHHHHHH
RDMTTPALHIVGWFDFFAPEATRAYTRMRAQAATPQAREGQRLIVGPWDHTYQDAAYRSR
CCCCCCHHHEEHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCCHHHHHHHHH
EFGQLAGAPYADITGAHLRFFDRHLRGNNSADVGASPVRIFVMGVDQWRDEQDWPLPDTT
HHHHHCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCEEEEEEECHHHCCCCCCCCCCCE
YVDYYLDGPGRANTADGDGVLTTEAPTTEAAESYRFDPLDPVPTLGGRLNQMGFGFSALY
EEEEEECCCCCCCCCCCCCEEECCCCCCHHHHHCCCCCCCCCCCCCCCHHHCCCCHHHHH
SGPVDQRPVEERNDVLCFTTPVLEEPVEVTGNISLVLHASSSALDTDFTGKLVDVHPDGR
CCCCCCCCCHHCCCEEEEECHHHCCCCEECCCEEEEEEECCCCCCCCCCCCEEEECCCCC
ALYLTDGILRARYRESLANPKPLVPGEVYELILDLGLTSNVFLPGHRIRLEVSSSNFPRY
EEEEECHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCEECCCCEEEEEECCCCCCCC
DRNTNTGNVISFDTATPVVAGNQILHGPAHPSRLVLPIIRRLRTDRHG
CCCCCCCCEEEECCCCCEEECCCEEECCCCCCHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
SYRVEKNVMVPMRDDVTLCTDLFLPEGGPAPALIIRMGYSKEMFEKLSLPLIPNVLSLV
CEEECCCEEEECCCCCEEHHHEECCCCCCCCEEEEEECCCHHHHHHCCCCHHHHHHHHH
EAGYAIVYQECRGTYGSGGVFRPLVDDPDDGVDTLEWTVKQPWCDGNVGSYGLSYHGMTQ
HCCHHEEEHHHCCCCCCCCEECCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCEECCCHH
WATASQAPSGLKAMAVAASTTDLFRAPWYSDGGAVSWQMTLGWVAAQIVTLGQYALERGT
HCCCCCCCCCCEEEEEEECCHHHHCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHCCC
GDLEPLVDAGAMMLDLEPHLRKLPITDQPALNKHAPWWKEWWEHPTRDEFWTGLATAEHT
CCCCHHHHCCEEEEECCHHHHCCCCCCCCCCCCCCCHHHHHHCCCCCHHHHHCCHHHHHH
RDMTTPALHIVGWFDFFAPEATRAYTRMRAQAATPQAREGQRLIVGPWDHTYQDAAYRSR
CCCCCCHHHEEHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCCHHHHHHHHH
EFGQLAGAPYADITGAHLRFFDRHLRGNNSADVGASPVRIFVMGVDQWRDEQDWPLPDTT
HHHHHCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCEEEEEEECHHHCCCCCCCCCCCE
YVDYYLDGPGRANTADGDGVLTTEAPTTEAAESYRFDPLDPVPTLGGRLNQMGFGFSALY
EEEEEECCCCCCCCCCCCCEEECCCCCCHHHHHCCCCCCCCCCCCCCCHHHCCCCHHHHH
SGPVDQRPVEERNDVLCFTTPVLEEPVEVTGNISLVLHASSSALDTDFTGKLVDVHPDGR
CCCCCCCCCHHCCCEEEEECHHHCCCCEECCCEEEEEEECCCCCCCCCCCCEEEECCCCC
ALYLTDGILRARYRESLANPKPLVPGEVYELILDLGLTSNVFLPGHRIRLEVSSSNFPRY
EEEEECHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCEECCCCEEEEEECCCCCCCC
DRNTNTGNVISFDTATPVVAGNQILHGPAHPSRLVLPIIRRLRTDRHG
CCCCCCCCEEEECCCCCEEECCCEEECCCCCCHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10698749; 11742345; 12369817 [H]