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The map label for this gene is lrhA [H]

Identifier: 158313857

GI number: 158313857

Start: 2430453

End: 2431334

Strand: Direct

Name: lrhA [H]

Synonym: Franean1_2022

Alternate gene names: 158313857

Gene position: 2430453-2431334 (Clockwise)

Preceding gene: 158313852

Following gene: 158313859

Centisome position: 27.06

GC content: 76.76

Gene sequence:

>882_bases
ATGGCTGCCGTGTCCAACACGCTGGATCTGACGGCGCTGCGCAGTCTCGTGGCCATCGCCGACTGCGGTGGATTCCGCCG
CGCGGCCGAGGCGTTGTGCATCTCCCAGTCGGCGGTGAGCCAGCACGTGCGCCGCCTGGAGAAGGTGGTGGGCCGGCCCC
TGGTCGAGCTGGTCGGCCGCGGCTCCCGGTTCACCCCCGACGGCGAGCTGCTGCTCTCCGCCGGGCGGCGCATCCTCGCC
ACCCACGACGACGCGCTGGAGCTGCTCGGAGTGGGCGCGTCCGTCCTACAGCGCCTGATCACCGTCGGCTCGACCGAGCA
CGCCGCCGACCACCTGATCCCCCGGGTGATGGCCGTGCTCACCGAGCAGTTCCCGGACGTCGAGGTCAGGTTCCGCCTCG
ACCGCGGCGCCCGGCTCGCCCACGCCCTCGACCGCGGCACGCTGGACGTCGCCGTCCTGGTCGGGACGGGCGGAAGCCCC
GCGGGGCGCCCGGCCGGGCTGCTCCCGCTGGCGTGGTACTCGGCCCCCGGCTGGCTCGTCCCGCCGCCGGACCGCCCGCT
GCCCCTGGTCGCGGTCGACGACCCGTGCACGATCCGCACCCAGGCCCTGACGACCCTCGCCCGCGCCGGCCGGGTCGCGT
CGGTCGTCGGCGAGTCCGGCTACCTGGCCGGGGTCCTGCACGCGGCGCGGGCCGGCGTCGGAGTCGCCCTGCTGGCGGAC
GTCGGCCCGCCGCCGCAGGGCCTCGAGCGGCGGGCCGACCTTCCCGCGGTCGACCCCGAGCCCATGCAGGTCCGGCTACG
CCGCGGAGCCTCCCCACAGCTGGCCAGCCTCATCGCCGACGCAGTCGCATGCACCCTCGCCGCCGGCCGCGCCCCCGCCT
GA

Upstream 100 bases:

>100_bases
CACATTGCCCAGCATGTGCATCAGGATGGTTGGAAAATCGGGCAGTGTAAAGCCGCTCCGAGTGATCAAACCGATCGCAA
AACGTGATAGATCACATAGA

Downstream 100 bases:

>100_bases
CCACCCCCGCGGGCCGCTCACGGTCGCAGCGGGATGGCGAATCTGCCAGGTCGAAGTGGCCGGGTGGTGGAAGTGACTGC
TAGGAAACCGGTTCCAGGAC

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 293; Mature: 292

Protein sequence:

>293_residues
MAAVSNTLDLTALRSLVAIADCGGFRRAAEALCISQSAVSQHVRRLEKVVGRPLVELVGRGSRFTPDGELLLSAGRRILA
THDDALELLGVGASVLQRLITVGSTEHAADHLIPRVMAVLTEQFPDVEVRFRLDRGARLAHALDRGTLDVAVLVGTGGSP
AGRPAGLLPLAWYSAPGWLVPPPDRPLPLVAVDDPCTIRTQALTTLARAGRVASVVGESGYLAGVLHAARAGVGVALLAD
VGPPPQGLERRADLPAVDPEPMQVRLRRGASPQLASLIADAVACTLAAGRAPA

Sequences:

>Translated_293_residues
MAAVSNTLDLTALRSLVAIADCGGFRRAAEALCISQSAVSQHVRRLEKVVGRPLVELVGRGSRFTPDGELLLSAGRRILA
THDDALELLGVGASVLQRLITVGSTEHAADHLIPRVMAVLTEQFPDVEVRFRLDRGARLAHALDRGTLDVAVLVGTGGSP
AGRPAGLLPLAWYSAPGWLVPPPDRPLPLVAVDDPCTIRTQALTTLARAGRVASVVGESGYLAGVLHAARAGVGVALLAD
VGPPPQGLERRADLPAVDPEPMQVRLRRGASPQLASLIADAVACTLAAGRAPA
>Mature_292_residues
AAVSNTLDLTALRSLVAIADCGGFRRAAEALCISQSAVSQHVRRLEKVVGRPLVELVGRGSRFTPDGELLLSAGRRILAT
HDDALELLGVGASVLQRLITVGSTEHAADHLIPRVMAVLTEQFPDVEVRFRLDRGARLAHALDRGTLDVAVLVGTGGSPA
GRPAGLLPLAWYSAPGWLVPPPDRPLPLVAVDDPCTIRTQALTTLARAGRVASVVGESGYLAGVLHAARAGVGVALLADV
GPPPQGLERRADLPAVDPEPMQVRLRRGASPQLASLIADAVACTLAAGRAPA

Specific function: Not known, does not seem to act on the proton translocating NADH dehydrogenase genes (nuoA-N) which are part of the lrhA operon [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1788626, Length=234, Percent_Identity=35.042735042735, Blast_Score=117, Evalue=1e-27,
Organism=Escherichia coli, GI1790399, Length=267, Percent_Identity=28.0898876404494, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI1788748, Length=305, Percent_Identity=26.5573770491803, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI157672245, Length=155, Percent_Identity=30.3225806451613, Blast_Score=61, Evalue=1e-10,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 30452; Mature: 30320

Theoretical pI: Translated: 8.36; Mature: 8.36

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAAVSNTLDLTALRSLVAIADCGGFRRAAEALCISQSAVSQHVRRLEKVVGRPLVELVGR
CCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCC
GSRFTPDGELLLSAGRRILATHDDALELLGVGASVLQRLITVGSTEHAADHLIPRVMAVL
CCCCCCCHHHHHHCCCEEEECCHHHHHHHHCCHHHHHHHHHCCCCHHHHHHHHHHHHHHH
TEQFPDVEVRFRLDRGARLAHALDRGTLDVAVLVGTGGSPAGRPAGLLPLAWYSAPGWLV
HHCCCCEEEEEEECCCCHHHHHHCCCCEEEEEEEECCCCCCCCCCCCCEEHEECCCCCCC
PPPDRPLPLVAVDDPCTIRTQALTTLARAGRVASVVGESGYLAGVLHAARAGVGVALLAD
CCCCCCEEEEEECCCCCHHHHHHHHHHHHCHHHHHHCCCCHHHHHHHHHHHCCCEEEEEC
VGPPPQGLERRADLPAVDPEPMQVRLRRGASPQLASLIADAVACTLAAGRAPA
CCCCCHHHHHHCCCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
AAVSNTLDLTALRSLVAIADCGGFRRAAEALCISQSAVSQHVRRLEKVVGRPLVELVGR
CCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCC
GSRFTPDGELLLSAGRRILATHDDALELLGVGASVLQRLITVGSTEHAADHLIPRVMAVL
CCCCCCCHHHHHHCCCEEEECCHHHHHHHHCCHHHHHHHHHCCCCHHHHHHHHHHHHHHH
TEQFPDVEVRFRLDRGARLAHALDRGTLDVAVLVGTGGSPAGRPAGLLPLAWYSAPGWLV
HHCCCCEEEEEEECCCCHHHHHHCCCCEEEEEEEECCCCCCCCCCCCCEEHEECCCCCCC
PPPDRPLPLVAVDDPCTIRTQALTTLARAGRVASVVGESGYLAGVLHAARAGVGVALLAD
CCCCCCEEEEEECCCCCHHHHHHHHHHHHCHHHHHHCCCCHHHHHHHHHHHCCCEEEEEC
VGPPPQGLERRADLPAVDPEPMQVRLRRGASPQLASLIADAVACTLAAGRAPA
CCCCCHHHHHHCCCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]