Click here to switch to the map view.

The map label for this gene is argG [H]

Identifier: 158313579

GI number: 158313579

Start: 2082694

End: 2083896

Strand: Direct

Name: argG [H]

Synonym: Franean1_1743

Alternate gene names: 158313579

Gene position: 2082694-2083896 (Clockwise)

Preceding gene: 158313578

Following gene: 158313580

Centisome position: 23.19

GC content: 70.91

Gene sequence:

>1203_bases
GTGACCGAACGCGTCGTGCTTGCCTACTCGGGCGGCCTCGACACGTCCGTGGCCATCGGCTGGATCGGTGCCGAGACCGG
CGCCGAGGTCATCGCCCTGGCCGTCGACGTGGGCCAGGGCGGCGAGGACCTCGAGGCGATCCGCCAGCGCGCCTTCACCT
GCGGCGCCGTCGAGTCGATCGTCGTCGACGCCCGCGAGGAGTTCGCGGCATCCTTCGTCGCCCCGGCGATCCGCGCCAAC
GCCCTGTACATGGACCGCTACCCGCTCATCTCCTCGCTGTCCCGGCCGATCATCGTGAAGCACCTGGTCGAGGCCGCCAA
ACAGCACGGGGCGGACGCGATCTCGCACGGCTGCACGGGCAAGGGCAACGACCAGGTCCGCTTCGAGGTCGGCGTGATGG
CACTGGCCCCGGGCCTGCGCGTGCTGGCCCCGGTGCGCGACTCGGGCATGACCCGGGACAAGGCGATCGCCTTCGCCGAG
GAGCGTGGCCTGCCGATCGACGTCTCGAAGAAGTCCCCGTACTCGATCGACCAGAACCTGTGGGGCCGCACGGCCGAGTG
CGGGGTCCTCGAGGACCCGTGGGCGCAGCCGCCGGAGGACGTCTTCGTCTACACGGCCGACCCGACGGTCTCCCGGCCGT
CCGACGAGGTCACGATCTCGTTCACCGACGGCCTGCCGACCGGGCTGGACGGGCGGGCACTGTCGCTGGTGGACCTCGTC
GCCGAGCTCAACACCCGGGCGGGTGCCCAGGGCGTCGGTCGCATCGACATGATCGAGGACCGGCTCGTCGGCATCAAGAG
CCGGGAGATCTACGAGTGCCCAGCGGCGATCACGCTGCTGACCGCGCACCGTGACCTGGAGGACCTCACCCTCGAGCGGG
ACGTCGCCCGGTTCAAGCGGGGCATCGACCAGCGCTGGGGCGAAATCGTCTATGACGGGCTGTGGTTCTCGCCGTTGCGG
GCAGCCCTCGACGCCTTCGTGGACTCGGCCAGTGTCGGTGTCACCGGCGACGTCCGGATCCGGCTGGCGGGCGGCGTCGC
CCAGGTCGTGGGCCGTCGCAGCCCGGGCAGTCTCTACGACCACGCGCTGGCCACCTACGATGCCGGCGACCAGTTCGACC
AGACCGACGCGCGGGGATTCATCGAGCTGTGGGGCCTGCCCACCAAGGTCTGGGCGGCCCGCGAACAGCGGCTCAACCCG
TGA

Upstream 100 bases:

>100_bases
ACCGGCGCGGGCGCCGGCTGAGGACCAGGCGGGGCAGACCTCCCGTCCACCGGCGTCATGAACGACCACGTGAACCGAGA
ATCAACTAAGGAGTGACTCC

Downstream 100 bases:

>100_bases
CGTCGATCCGGTCGGTGGCGACTGGGAGTCACCCAGCGGCCGACGAGGAGCAGGAACGGATGGATCCCGAACGGGCACAG
GGCGACGTCGCGCGCACGGA

Product: argininosuccinate synthase

Products: NA

Alternate protein names: Citrulline--aspartate ligase [H]

Number of amino acids: Translated: 400; Mature: 399

Protein sequence:

>400_residues
MTERVVLAYSGGLDTSVAIGWIGAETGAEVIALAVDVGQGGEDLEAIRQRAFTCGAVESIVVDAREEFAASFVAPAIRAN
ALYMDRYPLISSLSRPIIVKHLVEAAKQHGADAISHGCTGKGNDQVRFEVGVMALAPGLRVLAPVRDSGMTRDKAIAFAE
ERGLPIDVSKKSPYSIDQNLWGRTAECGVLEDPWAQPPEDVFVYTADPTVSRPSDEVTISFTDGLPTGLDGRALSLVDLV
AELNTRAGAQGVGRIDMIEDRLVGIKSREIYECPAAITLLTAHRDLEDLTLERDVARFKRGIDQRWGEIVYDGLWFSPLR
AALDAFVDSASVGVTGDVRIRLAGGVAQVVGRRSPGSLYDHALATYDAGDQFDQTDARGFIELWGLPTKVWAAREQRLNP

Sequences:

>Translated_400_residues
MTERVVLAYSGGLDTSVAIGWIGAETGAEVIALAVDVGQGGEDLEAIRQRAFTCGAVESIVVDAREEFAASFVAPAIRAN
ALYMDRYPLISSLSRPIIVKHLVEAAKQHGADAISHGCTGKGNDQVRFEVGVMALAPGLRVLAPVRDSGMTRDKAIAFAE
ERGLPIDVSKKSPYSIDQNLWGRTAECGVLEDPWAQPPEDVFVYTADPTVSRPSDEVTISFTDGLPTGLDGRALSLVDLV
AELNTRAGAQGVGRIDMIEDRLVGIKSREIYECPAAITLLTAHRDLEDLTLERDVARFKRGIDQRWGEIVYDGLWFSPLR
AALDAFVDSASVGVTGDVRIRLAGGVAQVVGRRSPGSLYDHALATYDAGDQFDQTDARGFIELWGLPTKVWAAREQRLNP
>Mature_399_residues
TERVVLAYSGGLDTSVAIGWIGAETGAEVIALAVDVGQGGEDLEAIRQRAFTCGAVESIVVDAREEFAASFVAPAIRANA
LYMDRYPLISSLSRPIIVKHLVEAAKQHGADAISHGCTGKGNDQVRFEVGVMALAPGLRVLAPVRDSGMTRDKAIAFAEE
RGLPIDVSKKSPYSIDQNLWGRTAECGVLEDPWAQPPEDVFVYTADPTVSRPSDEVTISFTDGLPTGLDGRALSLVDLVA
ELNTRAGAQGVGRIDMIEDRLVGIKSREIYECPAAITLLTAHRDLEDLTLERDVARFKRGIDQRWGEIVYDGLWFSPLRA
ALDAFVDSASVGVTGDVRIRLAGGVAQVVGRRSPGSLYDHALATYDAGDQFDQTDARGFIELWGLPTKVWAAREQRLNP

Specific function: Arginine biosynthesis; seventh step. [C]

COG id: COG0137

COG function: function code E; Argininosuccinate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the argininosuccinate synthase family. Type 1 subfamily [H]

Homologues:

Organism=Homo sapiens, GI53759107, Length=405, Percent_Identity=39.5061728395062, Blast_Score=286, Evalue=3e-77,
Organism=Homo sapiens, GI16950633, Length=405, Percent_Identity=39.5061728395062, Blast_Score=286, Evalue=3e-77,
Organism=Escherichia coli, GI1789563, Length=397, Percent_Identity=30.2267002518892, Blast_Score=132, Evalue=3e-32,
Organism=Saccharomyces cerevisiae, GI6324514, Length=411, Percent_Identity=36.4963503649635, Blast_Score=258, Evalue=1e-69,
Organism=Drosophila melanogaster, GI21358151, Length=396, Percent_Identity=38.3838383838384, Blast_Score=272, Evalue=2e-73,

Paralogues:

None

Copy number: 380 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001518
- InterPro:   IPR018223
- InterPro:   IPR014729 [H]

Pfam domain/function: PF00764 Arginosuc_synth [H]

EC number: =6.3.4.5 [H]

Molecular weight: Translated: 43164; Mature: 43033

Theoretical pI: Translated: 4.58; Mature: 4.58

Prosite motif: PS00564 ARGININOSUCCIN_SYN_1 ; PS00565 ARGININOSUCCIN_SYN_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTERVVLAYSGGLDTSVAIGWIGAETGAEVIALAVDVGQGGEDLEAIRQRAFTCGAVESI
CCCEEEEEECCCCCCEEEEEEEECCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHH
VVDAREEFAASFVAPAIRANALYMDRYPLISSLSRPIIVKHLVEAAKQHGADAISHGCTG
HHHHHHHHHHHHHHHHHHCCEEEECCCHHHHHCCCHHHHHHHHHHHHHCCCHHHHCCCCC
KGNDQVRFEVGVMALAPGLRVLAPVRDSGMTRDKAIAFAEERGLPIDVSKKSPYSIDQNL
CCCCEEEEEEEEEECCCCCEEEEECCCCCCCHHHHEEEHHHCCCEEEECCCCCCCCCHHH
WGRTAECGVLEDPWAQPPEDVFVYTADPTVSRPSDEVTISFTDGLPTGLDGRALSLVDLV
CCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCEEEEECCCCCCCCCCCHHHHHHHH
AELNTRAGAQGVGRIDMIEDRLVGIKSREIYECPAAITLLTAHRDLEDLTLERDVARFKR
HHHHHCCCCCCCCCHHHHHHHHHCCCCCCCEECCCCEEEEEHHCCHHHHHHHHHHHHHHH
GIDQRWGEIVYDGLWFSPLRAALDAFVDSASVGVTGDVRIRLAGGVAQVVGRRSPGSLYD
HHHHHHHHHEECCCCHHHHHHHHHHHHCCCCCCCCCCEEEEEECCHHHHHCCCCCCCHHH
HALATYDAGDQFDQTDARGFIELWGLPTKVWAAREQRLNP
HHHHCCCCCCCCCCCCCCCEEEECCCCHHHHHHHHHCCCC
>Mature Secondary Structure 
TERVVLAYSGGLDTSVAIGWIGAETGAEVIALAVDVGQGGEDLEAIRQRAFTCGAVESI
CCEEEEEECCCCCCEEEEEEEECCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHH
VVDAREEFAASFVAPAIRANALYMDRYPLISSLSRPIIVKHLVEAAKQHGADAISHGCTG
HHHHHHHHHHHHHHHHHHCCEEEECCCHHHHHCCCHHHHHHHHHHHHHCCCHHHHCCCCC
KGNDQVRFEVGVMALAPGLRVLAPVRDSGMTRDKAIAFAEERGLPIDVSKKSPYSIDQNL
CCCCEEEEEEEEEECCCCCEEEEECCCCCCCHHHHEEEHHHCCCEEEECCCCCCCCCHHH
WGRTAECGVLEDPWAQPPEDVFVYTADPTVSRPSDEVTISFTDGLPTGLDGRALSLVDLV
CCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCEEEEECCCCCCCCCCCHHHHHHHH
AELNTRAGAQGVGRIDMIEDRLVGIKSREIYECPAAITLLTAHRDLEDLTLERDVARFKR
HHHHHCCCCCCCCCHHHHHHHHHCCCCCCCEECCCCEEEEEHHCCHHHHHHHHHHHHHHH
GIDQRWGEIVYDGLWFSPLRAALDAFVDSASVGVTGDVRIRLAGGVAQVVGRRSPGSLYD
HHHHHHHHHEECCCCHHHHHHHHHHHHCCCCCCCCCCEEEEEECCHHHHHCCCCCCCHHH
HALATYDAGDQFDQTDARGFIELWGLPTKVWAAREQRLNP
HHHHCCCCCCCCCCCCCCCEEEECCCCHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA