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The map label for this gene is yycR [H]

Identifier: 158313410

GI number: 158313410

Start: 1878602

End: 1879735

Strand: Direct

Name: yycR [H]

Synonym: Franean1_1573

Alternate gene names: 158313410

Gene position: 1878602-1879735 (Clockwise)

Preceding gene: 158313409

Following gene: 158313413

Centisome position: 20.92

GC content: 72.13

Gene sequence:

>1134_bases
ATGCGCGCAGTCGTCTACCGGGAACCGTTCCAGGTGGCCGTGGCGGACGTCCCCGACCCGCGCGTCGAGCATCCGCAGGA
CGCGATCGTGCGGGTCTCCTCGACGAGCATCTGCGGTTCCGATCTGCACGTGTACGAGGGACGTACCAGTGTGCGGCCCG
GCACGGTTCTCGGCCACGAGAACATGGGCACGGTCGTCGACCGCGGGTCGGCGGTGAGCCACGTCCAGCTCGGCGACCGG
GTCTCCGTTCCCTGCACCGTCTCCTGCGGGACGTGCGCGAACTGCGAGCGGGGCCGGACAGAGTTCTGCCTGCGCACCAA
CCCCGACCCGCACCGGGCCGGAGCGGCGTACGGCTGCCCGGACATGGGCCCCTACCTCGGCGGGCAGGCCGAGTACCTCC
GGGTGCCGTTCGCCGACTTCAACCTGCTGCGGCTGCCGCCGGGCGACGACCAGGAGCTCGACTTCGCAACCCTCTCCGAC
GTCTTCCCCACCGGCTTCCACGGCACCGAGCTGGCCGACGTCCAGGCCGGGAACACGGTTGTCGTGTTCGGCGCAGGGCC
GGTCGGCCTGCTGGCGGCGTACTCGGCCGCCCTGCGCGGCGCCACCGCGCTGGTGGTCGATCCCGTGCCCTCCCGGCTCC
GCCTGTGCGAGCGGATCGGCGCCACCGGGATCGACTCGTCCACCGAGGACGCCGCGGAACGGGTGCGGGAGGAGACACGC
GGCCGCGGCGTCGACTGCGGCATCGACGCCGTCGGCTACCAGGCCAGGACGGCGTCCGGCGAGGAGCAGGCCGGCCTCGT
CCTGAACCAGCTCGTCGACTGCGTGCGCTGGACGGGCTCGATCGGTGTCCTCGGCGTGTACCCCACCCGCGACCCCGGTG
CCGCCGACGAGAGCGGCGCACGCGGCCGACTCCCGTTCGACATGGGCGCCTTCTTCGCGAAGGGGCTGCGGATGGGCAGC
GGGCCGGCCAATGTGAAACGGTACAACCGGTTCCTGCGCGATCTCATCATCACCGGCCGGGCGCAGCCGTCCTGCGTCAT
GTCCCATCAGCTGCCGCTGGCCGACGCACCCGACGCCTACGCCCGCTTCGACCACCGGGACGCGGGCTGGATCAAGATCA
CCCTCCAGCCCTGA

Upstream 100 bases:

>100_bases
GGATCACCTACACCGCCACCGGGGTCGTGCTCGACCTGCTCGACCGGATCGACGAGCTCGAGCGGCTGCTGCGGCAACCC
CAGCGGGGAAGGTGAGCGCC

Downstream 100 bases:

>100_bases
CTCCGGCCGGCCCGGCCCGGCCTGGCGAAGTGCGGCGCGTGAGTGAGTCCTGGGTGTCACTCGCCCGCCACACTTCTCAG
CCCAGGAGCTGGCTGGTCAC

Product: alcohol dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 377; Mature: 377

Protein sequence:

>377_residues
MRAVVYREPFQVAVADVPDPRVEHPQDAIVRVSSTSICGSDLHVYEGRTSVRPGTVLGHENMGTVVDRGSAVSHVQLGDR
VSVPCTVSCGTCANCERGRTEFCLRTNPDPHRAGAAYGCPDMGPYLGGQAEYLRVPFADFNLLRLPPGDDQELDFATLSD
VFPTGFHGTELADVQAGNTVVVFGAGPVGLLAAYSAALRGATALVVDPVPSRLRLCERIGATGIDSSTEDAAERVREETR
GRGVDCGIDAVGYQARTASGEEQAGLVLNQLVDCVRWTGSIGVLGVYPTRDPGAADESGARGRLPFDMGAFFAKGLRMGS
GPANVKRYNRFLRDLIITGRAQPSCVMSHQLPLADAPDAYARFDHRDAGWIKITLQP

Sequences:

>Translated_377_residues
MRAVVYREPFQVAVADVPDPRVEHPQDAIVRVSSTSICGSDLHVYEGRTSVRPGTVLGHENMGTVVDRGSAVSHVQLGDR
VSVPCTVSCGTCANCERGRTEFCLRTNPDPHRAGAAYGCPDMGPYLGGQAEYLRVPFADFNLLRLPPGDDQELDFATLSD
VFPTGFHGTELADVQAGNTVVVFGAGPVGLLAAYSAALRGATALVVDPVPSRLRLCERIGATGIDSSTEDAAERVREETR
GRGVDCGIDAVGYQARTASGEEQAGLVLNQLVDCVRWTGSIGVLGVYPTRDPGAADESGARGRLPFDMGAFFAKGLRMGS
GPANVKRYNRFLRDLIITGRAQPSCVMSHQLPLADAPDAYARFDHRDAGWIKITLQP
>Mature_377_residues
MRAVVYREPFQVAVADVPDPRVEHPQDAIVRVSSTSICGSDLHVYEGRTSVRPGTVLGHENMGTVVDRGSAVSHVQLGDR
VSVPCTVSCGTCANCERGRTEFCLRTNPDPHRAGAAYGCPDMGPYLGGQAEYLRVPFADFNLLRLPPGDDQELDFATLSD
VFPTGFHGTELADVQAGNTVVVFGAGPVGLLAAYSAALRGATALVVDPVPSRLRLCERIGATGIDSSTEDAAERVREETR
GRGVDCGIDAVGYQARTASGEEQAGLVLNQLVDCVRWTGSIGVLGVYPTRDPGAADESGARGRLPFDMGAFFAKGLRMGS
GPANVKRYNRFLRDLIITGRAQPSCVMSHQLPLADAPDAYARFDHRDAGWIKITLQP

Specific function: Unknown

COG id: COG1063

COG function: function code ER; Threonine dehydrogenase and related Zn-dependent dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI156627571, Length=264, Percent_Identity=28.030303030303, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI4501933, Length=259, Percent_Identity=26.2548262548263, Blast_Score=68, Evalue=1e-11,
Organism=Homo sapiens, GI34577061, Length=259, Percent_Identity=26.2548262548263, Blast_Score=68, Evalue=2e-11,
Organism=Homo sapiens, GI4501939, Length=292, Percent_Identity=23.972602739726, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI156523966, Length=292, Percent_Identity=23.972602739726, Blast_Score=67, Evalue=3e-11,
Organism=Escherichia coli, GI1786825, Length=403, Percent_Identity=36.7245657568238, Blast_Score=215, Evalue=3e-57,
Organism=Escherichia coli, GI1790045, Length=284, Percent_Identity=31.3380281690141, Blast_Score=116, Evalue=2e-27,
Organism=Escherichia coli, GI226510992, Length=341, Percent_Identity=28.4457478005865, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI87082125, Length=373, Percent_Identity=28.9544235924933, Blast_Score=103, Evalue=3e-23,
Organism=Escherichia coli, GI1788073, Length=255, Percent_Identity=30.1960784313725, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1788075, Length=329, Percent_Identity=26.4437689969605, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1787863, Length=387, Percent_Identity=24.031007751938, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1788407, Length=242, Percent_Identity=28.5123966942149, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI87081918, Length=247, Percent_Identity=29.9595141700405, Blast_Score=78, Evalue=8e-16,
Organism=Escherichia coli, GI1786552, Length=229, Percent_Identity=29.2576419213974, Blast_Score=62, Evalue=7e-11,
Organism=Caenorhabditis elegans, GI17562876, Length=273, Percent_Identity=28.5714285714286, Blast_Score=94, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17562878, Length=223, Percent_Identity=29.1479820627803, Blast_Score=87, Evalue=2e-17,
Organism=Saccharomyces cerevisiae, GI6322619, Length=369, Percent_Identity=29.2682926829268, Blast_Score=109, Evalue=6e-25,
Organism=Saccharomyces cerevisiae, GI6319955, Length=369, Percent_Identity=28.9972899728997, Blast_Score=107, Evalue=4e-24,
Organism=Saccharomyces cerevisiae, GI6323099, Length=231, Percent_Identity=32.4675324675325, Blast_Score=103, Evalue=4e-23,
Organism=Saccharomyces cerevisiae, GI6319258, Length=286, Percent_Identity=25.8741258741259, Blast_Score=83, Evalue=7e-17,
Organism=Saccharomyces cerevisiae, GI6320033, Length=274, Percent_Identity=31.021897810219, Blast_Score=82, Evalue=1e-16,
Organism=Saccharomyces cerevisiae, GI6319257, Length=316, Percent_Identity=25.9493670886076, Blast_Score=82, Evalue=1e-16,
Organism=Saccharomyces cerevisiae, GI6323729, Length=251, Percent_Identity=26.2948207171315, Blast_Score=67, Evalue=3e-12,
Organism=Drosophila melanogaster, GI17137530, Length=239, Percent_Identity=29.7071129707113, Blast_Score=90, Evalue=2e-18,
Organism=Drosophila melanogaster, GI17737897, Length=238, Percent_Identity=29.4117647058824, Blast_Score=86, Evalue=3e-17,
Organism=Drosophila melanogaster, GI221457811, Length=200, Percent_Identity=27.5, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI45550770, Length=200, Percent_Identity=27.5, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI45551930, Length=200, Percent_Identity=27.5, Blast_Score=70, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR002328
- InterPro:   IPR011032
- InterPro:   IPR014184
- InterPro:   IPR016040 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: NA

Molecular weight: Translated: 40230; Mature: 40230

Theoretical pI: Translated: 5.64; Mature: 5.64

Prosite motif: PS00059 ADH_ZINC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.9 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
2.9 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRAVVYREPFQVAVADVPDPRVEHPQDAIVRVSSTSICGSDLHVYEGRTSVRPGTVLGHE
CCEEEEECCCEEEEECCCCCCCCCCCCCEEEEECCCCCCCCEEEECCCCCCCCCEEECCC
NMGTVVDRGSAVSHVQLGDRVSVPCTVSCGTCANCERGRTEFCLRTNPDPHRAGAAYGCP
CCCCEEECCCCEEEEECCCCCCCCEEEECCCCCCCCCCCCEEEEECCCCHHHCCCCCCCC
DMGPYLGGQAEYLRVPFADFNLLRLPPGDDQELDFATLSDVFPTGFHGTELADVQAGNTV
CCCCCCCCCCEEEEECCCCCEEEECCCCCCCCCCHHHHHHHCCCCCCCCEEEEECCCCEE
VVFGAGPVGLLAAYSAALRGATALVVDPVPSRLRLCERIGATGIDSSTEDAAERVREETR
EEECCCHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHC
GRGVDCGIDAVGYQARTASGEEQAGLVLNQLVDCVRWTGSIGVLGVYPTRDPGAADESGA
CCCCCCCCCCCCCEEECCCCCHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCC
RGRLPFDMGAFFAKGLRMGSGPANVKRYNRFLRDLIITGRAQPSCVMSHQLPLADAPDAY
CCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCCHHH
ARFDHRDAGWIKITLQP
HHCCCCCCCEEEEEECC
>Mature Secondary Structure
MRAVVYREPFQVAVADVPDPRVEHPQDAIVRVSSTSICGSDLHVYEGRTSVRPGTVLGHE
CCEEEEECCCEEEEECCCCCCCCCCCCCEEEEECCCCCCCCEEEECCCCCCCCCEEECCC
NMGTVVDRGSAVSHVQLGDRVSVPCTVSCGTCANCERGRTEFCLRTNPDPHRAGAAYGCP
CCCCEEECCCCEEEEECCCCCCCCEEEECCCCCCCCCCCCEEEEECCCCHHHCCCCCCCC
DMGPYLGGQAEYLRVPFADFNLLRLPPGDDQELDFATLSDVFPTGFHGTELADVQAGNTV
CCCCCCCCCCEEEEECCCCCEEEECCCCCCCCCCHHHHHHHCCCCCCCCEEEEECCCCEE
VVFGAGPVGLLAAYSAALRGATALVVDPVPSRLRLCERIGATGIDSSTEDAAERVREETR
EEECCCHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHC
GRGVDCGIDAVGYQARTASGEEQAGLVLNQLVDCVRWTGSIGVLGVYPTRDPGAADESGA
CCCCCCCCCCCCCEEECCCCCHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCC
RGRLPFDMGAFFAKGLRMGSGPANVKRYNRFLRDLIITGRAQPSCVMSHQLPLADAPDAY
CCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCCHHH
ARFDHRDAGWIKITLQP
HHCCCCCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: Zn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]