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The map label for this gene is degS [H]

Identifier: 158313274

GI number: 158313274

Start: 1728877

End: 1731072

Strand: Direct

Name: degS [H]

Synonym: Franean1_1434

Alternate gene names: 158313274

Gene position: 1728877-1731072 (Clockwise)

Preceding gene: 158313271

Following gene: 158313275

Centisome position: 19.25

GC content: 73.09

Gene sequence:

>2196_bases
GTGTTCGCTCAGGATCCGTCGCCGGCGCGGTCAGGGCGTCGACGGGCCGCGCACGTCCTGGCCCTGGCCGGGCTCGCGCT
GGCCGTCGCCGGCGGGGTGCTGGCCGTGGCCAACCGGCATGGGGATCTCACGCCGTCCGGGGACTCCGCGAGCATGGCGG
GCTGGACCCAGGTCGTCCTCGCGGTTCCGTTCGTGGCGGCCGGATGGCTGCTGGCAGTGCGCCGGCCGGAGGTTCCGTTT
GGTTGGTTGGCTCTGGCCGCCGCGATCGGCCACGGCGCGGCGGCCGCCGGCACAGGCTGGGCGGTGTTCACTGTGTTCGG
CGGGCGGGATCTGCCGGGGGCCGCGCCGGCGCTCCTCGCCGGCTCCACGTGTGGGGCGCTGGAGCCCCTCGTGCTGGTGA
TTATCTGGGCGACGTTCCCGCAGGGACGGTTCCCCCGCGGCTGGATCGGGCGGGTCGCGGCGGTCAGCGTCGGGTTGTGT
GCCGTGGGCTGGCTGAGCGGGCCGCTGTGGTCCTTCAGGTCCGGCGAGTCTCCGCCGGTCTATGCCGGTCTCACCAATCC
GATCGGGGTGGATGCCATCCCCGGTTGGCTGCCGGTCGCGCTGTTCTCCTCGGGCCTGCTGCTCGGGTCGGCCGTGATGG
TGGTCCGCTGGACGCGGGCGGACGGCGAGCTGCGCCAGGTGCTGCGCTGGCTGGCCGTGATCAACACGGCCGCGATCGTA
CTCACCCCCGTCGTCGTCGCGCTTCCTGCCGGAGAGCTGATCGGCAGTGTCGGCACCGTGGTCGAACTCGTCGTCGTCGT
CGCCGTGGTGCTCGCGAACCGTGTCTACGGCATCGAGGCGGTCCTCAACCGCACGCTCGTATACACGCTGCTCACCGCGT
TCGTGGCCGTCGTGTACGCGGCCGGCGTCGCGGTCCTCGCCGCGTTCGGCCAGCAGGTGGGCGGGACGTCCACGGTGCTC
GCCGCGGTCGGCGCGGCGTTCAGCCTCGCCCCGGCACGCGACCGGGTGCAACGCATGGTGAACCGCTTTCTCTACGGCGA
ACGCGACGAGCCGTACACCGTGGTGACCGGGGTGGCGGCGCGCCTGGAAGCGGCGGGCAGCGTACAGACCCTGCTGCCGG
GCCTGCTCGAAGCCCTGGTCGGGGCGCTGCGGCTGCCGTCTGCCGCGGTGGAGATGCGCGGCGACGACGGTTCCGCCCGT
TCCATCACCCACGGCGAGGCCGCGCGGCCGGGCGCGTCGGTCCGCTTCCCGCTGGTGCATCAGGGGCAGGACATCGGCGC
GCTCGTCGTCAGCCTGCGGGCCGGGCAGAACGCGCTGGCTCCGCGGGAGAACCGCCTGCTCACCGACATCGCCCGCCAGG
TCGCGGTGGCCGCCAGCAACGTGCAGCTCACCGAGGCGCTGATGCGCTCGCGCGAGCGCATCGTCAGCGCGGCGGAGGAG
GAACGCCGCCGGCTGCGCCACGACCTGCACGACGGTCTCGGACCCACGCTGACCGCCGCCGCGACCAAGGTGGACGCCGC
CGGCAACCTCGTCGACCGGGACGTGGCGCGGGCCAGGAACCTGCTCGACTCGGTCCGGCGGGACCTCACCTCGGCCCTCG
CCGACCTGCGCCGCCTGGTCTACGCCCTGAGGCCGCCCGTCCTCGACGAACTCGGGCTGCTGCCCGCGCTGCGCGAGCAG
CTTCGGCACGCCGCGGTCCCGGTCGTGGTGTCGGCGCCCGAATCCCTGCCGCCGCTGCCGGCGGCGGTGGAGATCGCCGC
TTACCGGATCATCACGGAAGCCATCACGAACGTCACCCGGCACGCCCGGGCGTCGTCCTGCGAAGTGTCGATCACCTGCG
TCGATCACCTGCGTGTCGAGATCCGCGACAACGGAACAGCCGGAGACGGCGCGACAGGAGACGGCGCGACAGGCGACACC
GCGACAGGCGGCACCGCGAGCGGGAGCGGGAGCGGAGCAACATGGGCACCCGGGGTCGGCCTGACCTCGATGCGGGAACG
GGCGACCGCGCTCGGTGGCAGCTGGATCGCCGGACCCACCGCTACCGGCGGCCGGGTCCTGGTAGAACTCCCCCTCTCCC
TCGCCGGAAGCGCGATACCCCGGTCCGCCGCCGTGGTCGCTCCAGAAAGGGATCACGGATCTTCTTCATCCGCGCACACC
GACGTCACCGGAATGCTCACGAGGAGCCAGCAGTGA

Upstream 100 bases:

>100_bases
AGGCGGACGGGATCAGCGGTCCCGCACACTGGGTCTCCACGGGGTGCGATCATGCGATCCTGCGCGCCCCACGGGTCTAG
GTGAGGGAGCTGGCTTGGAC

Downstream 100 bases:

>100_bases
CCGAACCCCCCGCCACCATTCGGGTGCTCCTCGCCGACGACCACCGCCTCGTGCTGGACGGCCTGTCCGCGCTGATCGAC
TCCGTCGACGGCCTCACCGT

Product: integral membrane sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 731; Mature: 731

Protein sequence:

>731_residues
MFAQDPSPARSGRRRAAHVLALAGLALAVAGGVLAVANRHGDLTPSGDSASMAGWTQVVLAVPFVAAGWLLAVRRPEVPF
GWLALAAAIGHGAAAAGTGWAVFTVFGGRDLPGAAPALLAGSTCGALEPLVLVIIWATFPQGRFPRGWIGRVAAVSVGLC
AVGWLSGPLWSFRSGESPPVYAGLTNPIGVDAIPGWLPVALFSSGLLLGSAVMVVRWTRADGELRQVLRWLAVINTAAIV
LTPVVVALPAGELIGSVGTVVELVVVVAVVLANRVYGIEAVLNRTLVYTLLTAFVAVVYAAGVAVLAAFGQQVGGTSTVL
AAVGAAFSLAPARDRVQRMVNRFLYGERDEPYTVVTGVAARLEAAGSVQTLLPGLLEALVGALRLPSAAVEMRGDDGSAR
SITHGEAARPGASVRFPLVHQGQDIGALVVSLRAGQNALAPRENRLLTDIARQVAVAASNVQLTEALMRSRERIVSAAEE
ERRRLRHDLHDGLGPTLTAAATKVDAAGNLVDRDVARARNLLDSVRRDLTSALADLRRLVYALRPPVLDELGLLPALREQ
LRHAAVPVVVSAPESLPPLPAAVEIAAYRIITEAITNVTRHARASSCEVSITCVDHLRVEIRDNGTAGDGATGDGATGDT
ATGGTASGSGSGATWAPGVGLTSMRERATALGGSWIAGPTATGGRVLVELPLSLAGSAIPRSAAVVAPERDHGSSSSAHT
DVTGMLTRSQQ

Sequences:

>Translated_731_residues
MFAQDPSPARSGRRRAAHVLALAGLALAVAGGVLAVANRHGDLTPSGDSASMAGWTQVVLAVPFVAAGWLLAVRRPEVPF
GWLALAAAIGHGAAAAGTGWAVFTVFGGRDLPGAAPALLAGSTCGALEPLVLVIIWATFPQGRFPRGWIGRVAAVSVGLC
AVGWLSGPLWSFRSGESPPVYAGLTNPIGVDAIPGWLPVALFSSGLLLGSAVMVVRWTRADGELRQVLRWLAVINTAAIV
LTPVVVALPAGELIGSVGTVVELVVVVAVVLANRVYGIEAVLNRTLVYTLLTAFVAVVYAAGVAVLAAFGQQVGGTSTVL
AAVGAAFSLAPARDRVQRMVNRFLYGERDEPYTVVTGVAARLEAAGSVQTLLPGLLEALVGALRLPSAAVEMRGDDGSAR
SITHGEAARPGASVRFPLVHQGQDIGALVVSLRAGQNALAPRENRLLTDIARQVAVAASNVQLTEALMRSRERIVSAAEE
ERRRLRHDLHDGLGPTLTAAATKVDAAGNLVDRDVARARNLLDSVRRDLTSALADLRRLVYALRPPVLDELGLLPALREQ
LRHAAVPVVVSAPESLPPLPAAVEIAAYRIITEAITNVTRHARASSCEVSITCVDHLRVEIRDNGTAGDGATGDGATGDT
ATGGTASGSGSGATWAPGVGLTSMRERATALGGSWIAGPTATGGRVLVELPLSLAGSAIPRSAAVVAPERDHGSSSSAHT
DVTGMLTRSQQ
>Mature_731_residues
MFAQDPSPARSGRRRAAHVLALAGLALAVAGGVLAVANRHGDLTPSGDSASMAGWTQVVLAVPFVAAGWLLAVRRPEVPF
GWLALAAAIGHGAAAAGTGWAVFTVFGGRDLPGAAPALLAGSTCGALEPLVLVIIWATFPQGRFPRGWIGRVAAVSVGLC
AVGWLSGPLWSFRSGESPPVYAGLTNPIGVDAIPGWLPVALFSSGLLLGSAVMVVRWTRADGELRQVLRWLAVINTAAIV
LTPVVVALPAGELIGSVGTVVELVVVVAVVLANRVYGIEAVLNRTLVYTLLTAFVAVVYAAGVAVLAAFGQQVGGTSTVL
AAVGAAFSLAPARDRVQRMVNRFLYGERDEPYTVVTGVAARLEAAGSVQTLLPGLLEALVGALRLPSAAVEMRGDDGSAR
SITHGEAARPGASVRFPLVHQGQDIGALVVSLRAGQNALAPRENRLLTDIARQVAVAASNVQLTEALMRSRERIVSAAEE
ERRRLRHDLHDGLGPTLTAAATKVDAAGNLVDRDVARARNLLDSVRRDLTSALADLRRLVYALRPPVLDELGLLPALREQ
LRHAAVPVVVSAPESLPPLPAAVEIAAYRIITEAITNVTRHARASSCEVSITCVDHLRVEIRDNGTAGDGATGDGATGDT
ATGGTASGSGSGATWAPGVGLTSMRERATALGGSWIAGPTATGGRVLVELPLSLAGSAIPRSAAVVAPERDHGSSSSAHT
DVTGMLTRSQQ

Specific function: Involved in a sensory transduction pathway that affect the production of enzymes that degrade polymeric carbon and nitrogen sources. DegS probably acts as a kinase that phosphorylates degU [H]

COG id: COG4585

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR008595
- InterPro:   IPR011712
- InterPro:   IPR005467
- InterPro:   IPR016381 [H]

Pfam domain/function: PF05384 DegS; PF02518 HATPase_c; PF07730 HisKA_3 [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 75318; Mature: 75318

Theoretical pI: Translated: 9.18; Mature: 9.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFAQDPSPARSGRRRAAHVLALAGLALAVAGGVLAVANRHGDLTPSGDSASMAGWTQVVL
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHEEECCCCCCCCCCCCCCHHHHHHHHH
AVPFVAAGWLLAVRRPEVPFGWLALAAAIGHGAAAAGTGWAVFTVFGGRDLPGAAPALLA
HHHHHHHHHHHEECCCCCCHHHHHHHHHHCCCCCCCCCCEEEEEEECCCCCCCCCHHHHC
GSTCGALEPLVLVIIWATFPQGRFPRGWIGRVAAVSVGLCAVGWLSGPLWSFRSGESPPV
CCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCE
YAGLTNPIGVDAIPGWLPVALFSSGLLLGSAVMVVRWTRADGELRQVLRWLAVINTAAIV
EECCCCCCCCCCCCHHHHHHHHHCCHHHHCEEEEEEEECCCHHHHHHHHHHHHHHHHHHH
LTPVVVALPAGELIGSVGTVVELVVVVAVVLANRVYGIEAVLNRTLVYTLLTAFVAVVYA
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AGVAVLAAFGQQVGGTSTVLAAVGAAFSLAPARDRVQRMVNRFLYGERDEPYTVVTGVAA
HHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCEEHHHHHHH
RLEAAGSVQTLLPGLLEALVGALRLPSAAVEMRGDDGSARSITHGEAARPGASVRFPLVH
HHHHCCCHHHHHHHHHHHHHHHHHCCCHHEEEECCCCCCCCCCCCCCCCCCCCEECCHHC
QGQDIGALVVSLRAGQNALAPRENRLLTDIARQVAVAASNVQLTEALMRSRERIVSAAEE
CCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
ERRRLRHDLHDGLGPTLTAAATKVDAAGNLVDRDVARARNLLDSVRRDLTSALADLRRLV
HHHHHHHHHHHCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YALRPPVLDELGLLPALREQLRHAAVPVVVSAPESLPPLPAAVEIAAYRIITEAITNVTR
HHHCCCHHHHHCCCHHHHHHHHHHCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHH
HARASSCEVSITCVDHLRVEIRDNGTAGDGATGDGATGDTATGGTASGSGSGATWAPGVG
HCCCCCCEEEEEEEEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
LTSMRERATALGGSWIAGPTATGGRVLVELPLSLAGSAIPRSAAVVAPERDHGSSSSAHT
HHHHHHHHHHCCCCCCCCCCCCCCEEEEEECHHHCCCCCCCCCEEECCCCCCCCCCCCCC
DVTGMLTRSQQ
CHHHHHCCCCC
>Mature Secondary Structure
MFAQDPSPARSGRRRAAHVLALAGLALAVAGGVLAVANRHGDLTPSGDSASMAGWTQVVL
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHEEECCCCCCCCCCCCCCHHHHHHHHH
AVPFVAAGWLLAVRRPEVPFGWLALAAAIGHGAAAAGTGWAVFTVFGGRDLPGAAPALLA
HHHHHHHHHHHEECCCCCCHHHHHHHHHHCCCCCCCCCCEEEEEEECCCCCCCCCHHHHC
GSTCGALEPLVLVIIWATFPQGRFPRGWIGRVAAVSVGLCAVGWLSGPLWSFRSGESPPV
CCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCE
YAGLTNPIGVDAIPGWLPVALFSSGLLLGSAVMVVRWTRADGELRQVLRWLAVINTAAIV
EECCCCCCCCCCCCHHHHHHHHHCCHHHHCEEEEEEEECCCHHHHHHHHHHHHHHHHHHH
LTPVVVALPAGELIGSVGTVVELVVVVAVVLANRVYGIEAVLNRTLVYTLLTAFVAVVYA
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AGVAVLAAFGQQVGGTSTVLAAVGAAFSLAPARDRVQRMVNRFLYGERDEPYTVVTGVAA
HHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCEEHHHHHHH
RLEAAGSVQTLLPGLLEALVGALRLPSAAVEMRGDDGSARSITHGEAARPGASVRFPLVH
HHHHCCCHHHHHHHHHHHHHHHHHCCCHHEEEECCCCCCCCCCCCCCCCCCCCEECCHHC
QGQDIGALVVSLRAGQNALAPRENRLLTDIARQVAVAASNVQLTEALMRSRERIVSAAEE
CCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
ERRRLRHDLHDGLGPTLTAAATKVDAAGNLVDRDVARARNLLDSVRRDLTSALADLRRLV
HHHHHHHHHHHCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YALRPPVLDELGLLPALREQLRHAAVPVVVSAPESLPPLPAAVEIAAYRIITEAITNVTR
HHHCCCHHHHHCCCHHHHHHHHHHCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHH
HARASSCEVSITCVDHLRVEIRDNGTAGDGATGDGATGDTATGGTASGSGSGATWAPGVG
HCCCCCCEEEEEEEEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
LTSMRERATALGGSWIAGPTATGGRVLVELPLSLAGSAIPRSAAVVAPERDHGSSSSAHT
HHHHHHHHHHCCCCCCCCCCCCCCEEEEEECHHHCCCCCCCCCEEECCCCCCCCCCCCCC
DVTGMLTRSQQ
CHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7765823 [H]