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The map label for this gene is hflX [H]

Identifier: 158313083

GI number: 158313083

Start: 1472802

End: 1474313

Strand: Direct

Name: hflX [H]

Synonym: Franean1_1231

Alternate gene names: 158313083

Gene position: 1472802-1474313 (Clockwise)

Preceding gene: 158313082

Following gene: 158313085

Centisome position: 16.4

GC content: 72.16

Gene sequence:

>1512_bases
ATGAGTCTTCGCGCTGACGCCGCTGTGGCGTCCACCCGGCATCTGAAACTGCACTCGGGCGAAAACGACGGCCACGACGG
CCACGACGGTCGTGACGGTCGCGCCGGCACCGCGCTCGCCCTGGCCGAGGCCGACGGGTTCTCGTTCTTCGACGAGGAGG
GCGACGGGCTCGACCTGGAGGACCGTGGCGCGCTGCGCCGTGTCCCGGGCCTCACCACCGAGCTCGAGGACGTCACCGAG
GTCGAGTACCGCCAGCTCCGGCTGGAACAGGTCGTTCTGATCGGGGTGTGGACGTCGGGCTCGCAGGTCGAGGCCGAGGC
GTCCATGGCGGAGCTGGCCGCGCTCGCCACCACCGCCGGCTCGGTCGTGCTCGACGCGCTCGTGCAGCGCCGGGACAGGC
CCGACGCAGCGACCTTCGTGGGCTCCGGCAAGGCCAAGGAGCTCGCCGAGATCGTACTGGCGACCGGCGCGGACACGGTG
ATCTGCGACGGCGAGCTGACCCCCGGCCAGCTGCGCCAGCTCGAGGAGGTCGTCAAGGTCAAGGTGATCGACCGGACGGC
GCTGATCCTCGACATCTTCGCCCAGCACGCGACGTCGCGCGAGGGCAAGGCGCAGGTCGAGCTCGCCCAGCTGCAGTACA
TGCTGCCGAGGCTGCGCGGCTGGGGTGAGTCGATGTCCCGGCAGGCCGCCAGCGGCGGCCGGGCGCCGATCGGTACCCGT
GGTCCCGGTGAGACGAAGATCGAGACGGACCGTCGCCGGCTGCGCGCGCGCATCACCAAGCTGCGCCGAGAGCTCACCGG
GATGGCCACCGTCCGGGCGACCAAGAGGTCGTCGCGCCGCCGCGGTGCCGTTCCCGCCGTCGCGATCGCCGGCTACACCA
ACGCCGGCAAGTCGTCGCTGCTCAACCGACTGACCGGGGCGGGCGTACTGGTCGAGGACGCGCTGTTCGCGACCCTCGAC
CCGACGGTGCGCCGGGCCACGCTGCCCGACGGCCGGATCTTCACCCTGGCCGACACGGTCGGCTTCGTGCGCCACCTGCC
GCACCAGATCGTCGAGGCGTTCCGCTCGACGCTCGAGGAGGTGGTGGACGCCGACCTCGTCCTGCACGTCGTCGACGGTT
CGGCCCCGGACCCGATGGGGCAGATCTCGGCTGTGCGCGAGGTGCTCGCCGAGATCGACGCGGCCGGGGTGCCCGAGCTC
ATCGTGGTCAACAAGGTGGACGCGGTCGACCCGACCACGCTCGCCGTCCTGCGCCAGGCGGTGCCGGACGCCATCTTCGT
CTCGGCGCGGTCCGGGGCGGGGCTGCAGGAGCTGGTGGAGGCGCTCTCGGCGCGGATACCGCACCCGGAGGTCGAGATGT
CCCTGCTGGTGCCCTACACCCGGGGCGATCTCGTCTCCCGCATCCACCAGATCGGCGAGGTGCTCCGAGTTGAGCACACC
GGCAAGGGCACCGAGGTCGCCGCGCGCGTGCCCGTGGGCCTGGCCGCCGAGCTGGAGCCGTTCCGCGCCTGA

Upstream 100 bases:

>100_bases
CATCGGCCGGGCGAACCCGGCTGATGGGGCGAAAGAGTGCCGTCCCGGCCGGGGCGGACTGGAATGACGCGGTCACCGTG
CCGCGTTGAGAACGGATGGT

Downstream 100 bases:

>100_bases
CGGCCCTGCCTGAACACCAGCCCCGACGGAACACCGCGAGCTGAACACCGCACCGGTCAGACGCCTGGCGTCTGACCGGT
GCCTGGCCTGCCCGGTGCGG

Product: small GTP-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 503; Mature: 502

Protein sequence:

>503_residues
MSLRADAAVASTRHLKLHSGENDGHDGHDGRDGRAGTALALAEADGFSFFDEEGDGLDLEDRGALRRVPGLTTELEDVTE
VEYRQLRLEQVVLIGVWTSGSQVEAEASMAELAALATTAGSVVLDALVQRRDRPDAATFVGSGKAKELAEIVLATGADTV
ICDGELTPGQLRQLEEVVKVKVIDRTALILDIFAQHATSREGKAQVELAQLQYMLPRLRGWGESMSRQAASGGRAPIGTR
GPGETKIETDRRRLRARITKLRRELTGMATVRATKRSSRRRGAVPAVAIAGYTNAGKSSLLNRLTGAGVLVEDALFATLD
PTVRRATLPDGRIFTLADTVGFVRHLPHQIVEAFRSTLEEVVDADLVLHVVDGSAPDPMGQISAVREVLAEIDAAGVPEL
IVVNKVDAVDPTTLAVLRQAVPDAIFVSARSGAGLQELVEALSARIPHPEVEMSLLVPYTRGDLVSRIHQIGEVLRVEHT
GKGTEVAARVPVGLAAELEPFRA

Sequences:

>Translated_503_residues
MSLRADAAVASTRHLKLHSGENDGHDGHDGRDGRAGTALALAEADGFSFFDEEGDGLDLEDRGALRRVPGLTTELEDVTE
VEYRQLRLEQVVLIGVWTSGSQVEAEASMAELAALATTAGSVVLDALVQRRDRPDAATFVGSGKAKELAEIVLATGADTV
ICDGELTPGQLRQLEEVVKVKVIDRTALILDIFAQHATSREGKAQVELAQLQYMLPRLRGWGESMSRQAASGGRAPIGTR
GPGETKIETDRRRLRARITKLRRELTGMATVRATKRSSRRRGAVPAVAIAGYTNAGKSSLLNRLTGAGVLVEDALFATLD
PTVRRATLPDGRIFTLADTVGFVRHLPHQIVEAFRSTLEEVVDADLVLHVVDGSAPDPMGQISAVREVLAEIDAAGVPEL
IVVNKVDAVDPTTLAVLRQAVPDAIFVSARSGAGLQELVEALSARIPHPEVEMSLLVPYTRGDLVSRIHQIGEVLRVEHT
GKGTEVAARVPVGLAAELEPFRA
>Mature_502_residues
SLRADAAVASTRHLKLHSGENDGHDGHDGRDGRAGTALALAEADGFSFFDEEGDGLDLEDRGALRRVPGLTTELEDVTEV
EYRQLRLEQVVLIGVWTSGSQVEAEASMAELAALATTAGSVVLDALVQRRDRPDAATFVGSGKAKELAEIVLATGADTVI
CDGELTPGQLRQLEEVVKVKVIDRTALILDIFAQHATSREGKAQVELAQLQYMLPRLRGWGESMSRQAASGGRAPIGTRG
PGETKIETDRRRLRARITKLRRELTGMATVRATKRSSRRRGAVPAVAIAGYTNAGKSSLLNRLTGAGVLVEDALFATLDP
TVRRATLPDGRIFTLADTVGFVRHLPHQIVEAFRSTLEEVVDADLVLHVVDGSAPDPMGQISAVREVLAEIDAAGVPELI
VVNKVDAVDPTTLAVLRQAVPDAIFVSARSGAGLQELVEALSARIPHPEVEMSLLVPYTRGDLVSRIHQIGEVLRVEHTG
KGTEVAARVPVGLAAELEPFRA

Specific function: Unknown

COG id: COG2262

COG function: function code R; GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI310124269, Length=213, Percent_Identity=38.0281690140845, Blast_Score=122, Evalue=8e-28,
Organism=Homo sapiens, GI310124267, Length=213, Percent_Identity=38.0281690140845, Blast_Score=122, Evalue=8e-28,
Organism=Homo sapiens, GI310124171, Length=213, Percent_Identity=38.0281690140845, Blast_Score=122, Evalue=8e-28,
Organism=Homo sapiens, GI310124169, Length=213, Percent_Identity=38.0281690140845, Blast_Score=122, Evalue=8e-28,
Organism=Homo sapiens, GI310133116, Length=220, Percent_Identity=37.2727272727273, Blast_Score=120, Evalue=4e-27,
Organism=Homo sapiens, GI310133118, Length=235, Percent_Identity=36.5957446808511, Blast_Score=120, Evalue=4e-27,
Organism=Escherichia coli, GI1790615, Length=386, Percent_Identity=45.3367875647668, Blast_Score=300, Evalue=2e-82,
Organism=Caenorhabditis elegans, GI17561038, Length=288, Percent_Identity=31.9444444444444, Blast_Score=136, Evalue=3e-32,
Organism=Drosophila melanogaster, GI24650079, Length=331, Percent_Identity=33.8368580060423, Blast_Score=128, Evalue=7e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009022
- InterPro:   IPR016496
- InterPro:   IPR006073
- InterPro:   IPR002917 [H]

Pfam domain/function: PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 53812; Mature: 53681

Theoretical pI: Translated: 5.41; Mature: 5.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLRADAAVASTRHLKLHSGENDGHDGHDGRDGRAGTALALAEADGFSFFDEEGDGLDLE
CCCCCCHHHHCCEEEEEECCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCC
DRGALRRVPGLTTELEDVTEVEYRQLRLEQVVLIGVWTSGSQVEAEASMAELAALATTAG
CCCCHHHCCCCCCHHHHHHHHHHHHHHHEEEEEEEEECCCCCCCHHHHHHHHHHHHHHHH
SVVLDALVQRRDRPDAATFVGSGKAKELAEIVLATGADTVICDGELTPGQLRQLEEVVKV
HHHHHHHHHHCCCCCHHHEECCCCHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHHH
KVIDRTALILDIFAQHATSREGKAQVELAQLQYMLPRLRGWGESMSRQAASGGRAPIGTR
HHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCC
GPGETKIETDRRRLRARITKLRRELTGMATVRATKRSSRRRGAVPAVAIAGYTNAGKSSL
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHH
LNRLTGAGVLVEDALFATLDPTVRRATLPDGRIFTLADTVGFVRHLPHQIVEAFRSTLEE
HHHHHCCCHHHHHHHHHHCCCHHHCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHH
VVDADLVLHVVDGSAPDPMGQISAVREVLAEIDAAGVPELIVVNKVDAVDPTTLAVLRQA
HHCHHEEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCHHHHHHHHHH
VPDAIFVSARSGAGLQELVEALSARIPHPEVEMSLLVPYTRGDLVSRIHQIGEVLRVEHT
CCCEEEEECCCCCCHHHHHHHHHHCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHCCC
GKGTEVAARVPVGLAAELEPFRA
CCCCEEEEECCCCCCCCCCCCCC
>Mature Secondary Structure 
SLRADAAVASTRHLKLHSGENDGHDGHDGRDGRAGTALALAEADGFSFFDEEGDGLDLE
CCCCCHHHHCCEEEEEECCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCC
DRGALRRVPGLTTELEDVTEVEYRQLRLEQVVLIGVWTSGSQVEAEASMAELAALATTAG
CCCCHHHCCCCCCHHHHHHHHHHHHHHHEEEEEEEEECCCCCCCHHHHHHHHHHHHHHHH
SVVLDALVQRRDRPDAATFVGSGKAKELAEIVLATGADTVICDGELTPGQLRQLEEVVKV
HHHHHHHHHHCCCCCHHHEECCCCHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHHH
KVIDRTALILDIFAQHATSREGKAQVELAQLQYMLPRLRGWGESMSRQAASGGRAPIGTR
HHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCC
GPGETKIETDRRRLRARITKLRRELTGMATVRATKRSSRRRGAVPAVAIAGYTNAGKSSL
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHH
LNRLTGAGVLVEDALFATLDPTVRRATLPDGRIFTLADTVGFVRHLPHQIVEAFRSTLEE
HHHHHCCCHHHHHHHHHHCCCHHHCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHH
VVDADLVLHVVDGSAPDPMGQISAVREVLAEIDAAGVPELIVVNKVDAVDPTTLAVLRQA
HHCHHEEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCHHHHHHHHHH
VPDAIFVSARSGAGLQELVEALSARIPHPEVEMSLLVPYTRGDLVSRIHQIGEVLRVEHT
CCCEEEEECCCCCCHHHHHHHHHHCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHCCC
GKGTEVAARVPVGLAAELEPFRA
CCCCEEEEECCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8248183; 7610040; 9278503; 2020545; 3040675 [H]