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The map label for this gene is kinB [H]

Identifier: 158312962

GI number: 158312962

Start: 1325146

End: 1326888

Strand: Direct

Name: kinB [H]

Synonym: Franean1_1110

Alternate gene names: 158312962

Gene position: 1325146-1326888 (Clockwise)

Preceding gene: 158312959

Following gene: 158312965

Centisome position: 14.75

GC content: 73.38

Gene sequence:

>1743_bases
ATGTCCTCCGTCAGCCCCTCCATGCCCGAACGGGCGCGCCGCCGTCACGGCAGCGCCCACGTCGGGCGCGCCGCCCGGCG
GCTCGAGAAGTCTCGGTCGTCCCGGTCACCCGCGGCGGATGCCGGGCTGGCCGCGGCGACCGCCGACGCCGCGCTCCGCG
GTCCCGTCGCGTGGTTCCCCCGCGGCCGCGGCCTGCCGACCGAGGACTGGGCCGCCCGCCACGCGCTGATGTGCTGGGTT
CTGGCCCTGCACCTTCCGGCCATCGTCGGGTACGCGCTGTGGCGCGACCACAGCCTCCCGCACGGCCTGCTGGCGGCGAG
CCCGCCGGCGCTGCTGTTCGCGGCCGCGCTGGCCCCCGGCATGCGGCGGGTGCGTGCGCTGGCCGCGAGCCTCGGCCTGC
TGTGCTGCTCGGTCGTCTTCGTGCATCTCTCCGACGGCCTGACCCCGATGTACTTCCACTTCTTCGTGGTGGTCGCGCTC
ATCGCGCTCTACGAGGACTGGACCGTCTACCTGCTGGCCATCGCCTTCGTCTTCCTCGCCATCCTCGCGATCGGCGACCT
GATCACCGATGAGGCCGCGTCGCGGATGGACAACGCCCTGCTCCTGGCAGGGCTCCACGCCGGCTTCATCTTCGCCCTGG
CCGGTGCCCAGATGGTCTTCTGGCACTACAACGAGCAGTCCCGTCGGCGGGTGGAGGACTACCGCCAGCAGCTCTACGAG
GGCCAGCAGAGCCTCATGGCCCGGCTGGAGGAGACCGACCGCATCCGCAGCGACCTGGTCGCCACGGTCTCGCACGAGTT
CCGGACGCCGCTGACGGGCATCCGGGGGACCCTGCTCACGATCAGGCGCCGCCGGGACCGCCTCTCCGACGCCCAGCTCG
ACGACATGCTCGACTCGGCCGTCACCTACTCGGACCGCCTGTCCAGGCTGCTGGAGAACATGCTGACGGCTGCCACGGCC
ACCGGCACCGACGACACCACCGCCGCCGACCTGCCCGAGGTCGTGCGCGAGGTGATCGCGAGCCTGAACTACGCCGGCAG
CAGCGTGACGGTCGACCTGCCGCCCCAGCTCCCGGTGCGGATGGCCCGCCAGGCGCTGCACCAGGTCGTGGCGAACCTTG
TGGACAACGCGCTGGTGCACTCCTGGCCGGGCGCCCCGGTGCGGCTCATCGCGGGCCGGGTCGGCGACGAGGTCGTCCTG
CGGGTCCGCAACCCCGGTCCGGATCTCGACCCGGCGACCATCCGCCAGCTCTTCGAGCCGTTCACCCAGCGGGACGGAAC
GGCGACCCGGCAGACCGACGGCGCCGGCATGGGGCTCTACGTGGTGCGGCGGCTGGTGGAGGTCCACGGCGGCCGGCTGC
GGATGTCCTCCGAGAACGGTGAGATCATCGTCGAGGTCGACCTGTGGGCGGCGTCCACGACATCGGCCACCACCGGCACG
GCCGATCCGGCTCCGATGCCGGTACCGATGCCGCTGCCACGCAGCATGCGCAACCGGTCGGATCTGCCCGACCCGCCCGC
GCTGCCCGCCGGTTCCGGTGCGCTGCTCGGGCCGAGGGGCGGTCCCGCCGCGCCTGGTCACAGCGTGGCGGCGCCGACGC
CGGAACCCGCGAACTTCCCCCGCCCCGCCTCGACACCACACCCGGCCGCGCCACCGCACGCCGCGTCCCGGCACATGACG
CCGTCGCCCCGGCACTGGGGCTCGAGATCCTCGTCGTCCCTGCCCGCCGACTGGCTGCACTGA

Upstream 100 bases:

>100_bases
GTGGTACAGATGGCCTAGTCAAAGCTGGGCATAGTCGTCATACGACACCACCCTTGACAGCCATGGTGCTCCACGGCCGG
AACGGGAGAAACTTGCTCGG

Downstream 100 bases:

>100_bases
CCTCGGAATACGACGCCCGGGTTCGACGGCGATTCTGCGCAGCGCAGGCCCGGGTCCGGTTGGCACCCGGCGTCGGATGC
GGCGGGGGCCTGCGGTCACG

Product: integral membrane sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 580; Mature: 579

Protein sequence:

>580_residues
MSSVSPSMPERARRRHGSAHVGRAARRLEKSRSSRSPAADAGLAAATADAALRGPVAWFPRGRGLPTEDWAARHALMCWV
LALHLPAIVGYALWRDHSLPHGLLAASPPALLFAAALAPGMRRVRALAASLGLLCCSVVFVHLSDGLTPMYFHFFVVVAL
IALYEDWTVYLLAIAFVFLAILAIGDLITDEAASRMDNALLLAGLHAGFIFALAGAQMVFWHYNEQSRRRVEDYRQQLYE
GQQSLMARLEETDRIRSDLVATVSHEFRTPLTGIRGTLLTIRRRRDRLSDAQLDDMLDSAVTYSDRLSRLLENMLTAATA
TGTDDTTAADLPEVVREVIASLNYAGSSVTVDLPPQLPVRMARQALHQVVANLVDNALVHSWPGAPVRLIAGRVGDEVVL
RVRNPGPDLDPATIRQLFEPFTQRDGTATRQTDGAGMGLYVVRRLVEVHGGRLRMSSENGEIIVEVDLWAASTTSATTGT
ADPAPMPVPMPLPRSMRNRSDLPDPPALPAGSGALLGPRGGPAAPGHSVAAPTPEPANFPRPASTPHPAAPPHAASRHMT
PSPRHWGSRSSSSLPADWLH

Sequences:

>Translated_580_residues
MSSVSPSMPERARRRHGSAHVGRAARRLEKSRSSRSPAADAGLAAATADAALRGPVAWFPRGRGLPTEDWAARHALMCWV
LALHLPAIVGYALWRDHSLPHGLLAASPPALLFAAALAPGMRRVRALAASLGLLCCSVVFVHLSDGLTPMYFHFFVVVAL
IALYEDWTVYLLAIAFVFLAILAIGDLITDEAASRMDNALLLAGLHAGFIFALAGAQMVFWHYNEQSRRRVEDYRQQLYE
GQQSLMARLEETDRIRSDLVATVSHEFRTPLTGIRGTLLTIRRRRDRLSDAQLDDMLDSAVTYSDRLSRLLENMLTAATA
TGTDDTTAADLPEVVREVIASLNYAGSSVTVDLPPQLPVRMARQALHQVVANLVDNALVHSWPGAPVRLIAGRVGDEVVL
RVRNPGPDLDPATIRQLFEPFTQRDGTATRQTDGAGMGLYVVRRLVEVHGGRLRMSSENGEIIVEVDLWAASTTSATTGT
ADPAPMPVPMPLPRSMRNRSDLPDPPALPAGSGALLGPRGGPAAPGHSVAAPTPEPANFPRPASTPHPAAPPHAASRHMT
PSPRHWGSRSSSSLPADWLH
>Mature_579_residues
SSVSPSMPERARRRHGSAHVGRAARRLEKSRSSRSPAADAGLAAATADAALRGPVAWFPRGRGLPTEDWAARHALMCWVL
ALHLPAIVGYALWRDHSLPHGLLAASPPALLFAAALAPGMRRVRALAASLGLLCCSVVFVHLSDGLTPMYFHFFVVVALI
ALYEDWTVYLLAIAFVFLAILAIGDLITDEAASRMDNALLLAGLHAGFIFALAGAQMVFWHYNEQSRRRVEDYRQQLYEG
QQSLMARLEETDRIRSDLVATVSHEFRTPLTGIRGTLLTIRRRRDRLSDAQLDDMLDSAVTYSDRLSRLLENMLTAATAT
GTDDTTAADLPEVVREVIASLNYAGSSVTVDLPPQLPVRMARQALHQVVANLVDNALVHSWPGAPVRLIAGRVGDEVVLR
VRNPGPDLDPATIRQLFEPFTQRDGTATRQTDGAGMGLYVVRRLVEVHGGRLRMSSENGEIIVEVDLWAASTTSATTGTA
DPAPMPVPMPLPRSMRNRSDLPDPPALPAGSGALLGPRGGPAAPGHSVAAPTPEPANFPRPASTPHPAAPPHAASRHMTP
SPRHWGSRSSSSLPADWLH

Specific function: Member of the two-component regulatory system AlgB/KinB involved in regulation of alginate biosynthesis genes. KinB functions as a membrane-associated protein kinase that phosphorylates AlgB, probably in response to environmental signals [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI145693157, Length=327, Percent_Identity=26.9113149847095, Blast_Score=82, Evalue=8e-17,
Organism=Escherichia coli, GI1788393, Length=228, Percent_Identity=27.1929824561404, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI1786600, Length=234, Percent_Identity=27.7777777777778, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI1789808, Length=207, Percent_Identity=28.5024154589372, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI1786783, Length=238, Percent_Identity=26.4705882352941, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI1789149, Length=232, Percent_Identity=27.1551724137931, Blast_Score=73, Evalue=5e-14,
Organism=Escherichia coli, GI1790346, Length=200, Percent_Identity=28, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1788549, Length=218, Percent_Identity=24.3119266055046, Blast_Score=69, Evalue=8e-13,
Organism=Escherichia coli, GI1788713, Length=255, Percent_Identity=25.8823529411765, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI87081816, Length=249, Percent_Identity=28.5140562248996, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI1786912, Length=216, Percent_Identity=28.2407407407407, Blast_Score=66, Evalue=6e-12,
Organism=Escherichia coli, GI1790436, Length=291, Percent_Identity=25.7731958762887, Blast_Score=63, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR013656
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF08448 PAS_4 [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 62628; Mature: 62497

Theoretical pI: Translated: 8.80; Mature: 8.80

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSVSPSMPERARRRHGSAHVGRAARRLEKSRSSRSPAADAGLAAATADAALRGPVAWFP
CCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCHHHCHHHHHHHHHHCCCCEECC
RGRGLPTEDWAARHALMCWVLALHLPAIVGYALWRDHSLPHGLLAASPPALLFAAALAPG
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHCCCHHHHHHHHHHHH
MRRVRALAASLGLLCCSVVFVHLSDGLTPMYFHFFVVVALIALYEDWTVYLLAIAFVFLA
HHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ILAIGDLITDEAASRMDNALLLAGLHAGFIFALAGAQMVFWHYNEQSRRRVEDYRQQLYE
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCEEEEEECCHHHHHHHHHHHHHHHH
GQQSLMARLEETDRIRSDLVATVSHEFRTPLTGIRGTLLTIRRRRDRLSDAQLDDMLDSA
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
VTYSDRLSRLLENMLTAATATGTDDTTAADLPEVVREVIASLNYAGSSVTVDLPPQLPVR
HHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCHH
MARQALHQVVANLVDNALVHSWPGAPVRLIAGRVGDEVVLRVRNPGPDLDPATIRQLFEP
HHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCEEEEEECCCCCCCCHHHHHHHHHH
FTQRDGTATRQTDGAGMGLYVVRRLVEVHGGRLRMSSENGEIIVEVDLWAASTTSATTGT
HHHCCCCCCCCCCCCCHHHHHHHHHHHHCCCEEEEECCCCCEEEEEEEEECCCCCCCCCC
ADPAPMPVPMPLPRSMRNRSDLPDPPALPAGSGALLGPRGGPAAPGHSVAAPTPEPANFP
CCCCCCCCCCCCCHHHHCCCCCCCCCCCCCCCCCEECCCCCCCCCCCCCCCCCCCCCCCC
RPASTPHPAAPPHAASRHMTPSPRHWGSRSSSSLPADWLH
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHCCC
>Mature Secondary Structure 
SSVSPSMPERARRRHGSAHVGRAARRLEKSRSSRSPAADAGLAAATADAALRGPVAWFP
CCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCHHHCHHHHHHHHHHCCCCEECC
RGRGLPTEDWAARHALMCWVLALHLPAIVGYALWRDHSLPHGLLAASPPALLFAAALAPG
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHCCCHHHHHHHHHHHH
MRRVRALAASLGLLCCSVVFVHLSDGLTPMYFHFFVVVALIALYEDWTVYLLAIAFVFLA
HHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ILAIGDLITDEAASRMDNALLLAGLHAGFIFALAGAQMVFWHYNEQSRRRVEDYRQQLYE
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCEEEEEECCHHHHHHHHHHHHHHHH
GQQSLMARLEETDRIRSDLVATVSHEFRTPLTGIRGTLLTIRRRRDRLSDAQLDDMLDSA
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
VTYSDRLSRLLENMLTAATATGTDDTTAADLPEVVREVIASLNYAGSSVTVDLPPQLPVR
HHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCHH
MARQALHQVVANLVDNALVHSWPGAPVRLIAGRVGDEVVLRVRNPGPDLDPATIRQLFEP
HHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCEEEEEECCCCCCCCHHHHHHHHHH
FTQRDGTATRQTDGAGMGLYVVRRLVEVHGGRLRMSSENGEIIVEVDLWAASTTSATTGT
HHHCCCCCCCCCCCCCHHHHHHHHHHHHCCCEEEEECCCCCEEEEEEEEECCCCCCCCCC
ADPAPMPVPMPLPRSMRNRSDLPDPPALPAGSGALLGPRGGPAAPGHSVAAPTPEPANFP
CCCCCCCCCCCCCHHHHCCCCCCCCCCCCCCCCCEECCCCCCCCCCCCCCCCCCCCCCCC
RPASTPHPAAPPHAASRHMTPSPRHWGSRSSSSLPADWLH
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9218420 [H]